Monocaprin
the 1-monoglyceride of capric acid (monocaprin) with microbicidal activities obtained by trans esterification using lipases from different sources
General
Type : Acyl-Glycerol, Monoacylglycerol, Fatty acid ester, Water-insoluble medium and long chain ester
Chemical_Nomenclature : 2,3-dihydroxypropyl decanoate
Canonical SMILES : CCCCCCCCCC(=O)OCC(CO)O
InChI : InChI=1S\/C13H26O4\/c1-2-3-4-5-6-7-8-9-13(16)17-11-12(15)10-14\/h12,14-15H,2-11H2,1H3
InChIKey : LKUNXBRZDFMZOK-UHFFFAOYSA-N
Other name(s) : 1-C10-MAG || 2,3-Dihydroxypropyl decanoate || Glyceryl caprate || 1-Monocaprin || 1-Monodecanoyl Glycerol || rac-glycerol 1-monodecanoate || RefChem:663493 || Glyceryl monocaprate || Decanoic acid, 2,3-dihydroxypropyl ester || CHEMBL1595008 || MG 10:0 || rac-1-decanoylglycerol || rac-1-monocaprylglycerol || SCHEMBL25295 || CHEBI:75547 || CHEBI:75551 || MAG 10:0 || MAG-C10:0
MW : 246.34
Formula : C13H26O4
CAS_number : 26402-22-2
PubChem : 92926
UniChem : LKUNXBRZDFMZOK-UHFFFAOYSA-N
Target
Structures : No structure
Families : Acidic_Lipase, abh_upf0017, Carb_B_Chordata, Lipase_3, BCHE, ABHD6-Lip, ABHD12-PHARC, Monoglyceridelipase_lysophospholip
References (10)
| Title : Biochemical characterization of the PHARC-associated serine hydrolase ABHD12 reveals its preference for very-long-chain lipids - Joshi_2018_J.Biol.Chem_293_16953 |
| Author(s) : Joshi A , Shaikh M , Singh S , Rajendran A , Mhetre A , Kamat SS |
| Ref : Journal of Biological Chemistry , 293 :16953 , 2018 |
| Abstract : |
| PubMedSearch : Joshi_2018_J.Biol.Chem_293_16953 |
| PubMedID: 30237167 |
| Gene_locus related to this paper: human-ABHD12 |
| Title : Selective production of 1-monocaprin by porcine liver carboxylesterase-catalyzed esterification: Its enzyme kinetics and catalytic performance - Park_2016_Enzyme.Microb.Technol_82_51 |
| Author(s) : Park KM , Lee JH , Hong SC , Kwon CW , Jo M , Choi SJ , Kim K , Chang PS |
| Ref : Enzyme Microb Technol , 82 :51 , 2016 |
| Abstract : |
| PubMedSearch : Park_2016_Enzyme.Microb.Technol_82_51 |
| PubMedID: 26672448 |
| Gene_locus related to this paper: pig-EST1 |
| Title : Mutation of cys242 of human monoacylglycerol lipase disrupts balanced hydrolysis of 1- and 2-monoacylglycerols and selectively impairs inhibitor potency - Laitinen_2014_Mol.Pharmacol_85_510 |
| Author(s) : Laitinen T , Navia-Paldanius D , Rytilahti R , Marjamaa JJ , Karizkova J , Parkkari T , Pantsar T , Poso A , Laitinen JT , Savinainen JR |
| Ref : Molecular Pharmacology , 85 :510 , 2014 |
| Abstract : |
| PubMedSearch : Laitinen_2014_Mol.Pharmacol_85_510 |
| PubMedID: 24368842 |
| Gene_locus related to this paper: human-MGLL |
| Title : Biochemical and pharmacological characterization of human alpha\/beta-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12) - Navia-Paldanius_2012_J.Lipid.Res_53_2413 |
| Author(s) : Navia-Paldanius D , Savinainen JR , Laitinen JT |
| Ref : J Lipid Res , 53 :2413 , 2012 |
| Abstract : |
| PubMedSearch : Navia-Paldanius_2012_J.Lipid.Res_53_2413 |
| PubMedID: 22969151 |
| Gene_locus related to this paper: human-ABHD6 , human-ABHD12 |
| Title : Characterization and optimization of carboxylesterase-catalyzed esterification between capric acid and glycerol for the production of 1-monocaprin in reversed micellar system - Park_2010_N.Biotechnol_27_46 |
| Author(s) : Park KM , Kwon OT , Ahn SM , Lee J , Chang PS |
| Ref : N Biotechnol , 27 :46 , 2010 |
| Abstract : |
| PubMedSearch : Park_2010_N.Biotechnol_27_46 |
| PubMedID: 19931658 |
| Gene_locus related to this paper: pig-EST1 |
| Title : Purification and biochemical characterization of a broad substrate specificity thermostable alkaline protease from Aspergillus nidulans - Pena-Montes_2008_Appl.Microbiol.Biotechnol_78_603 |
| Author(s) : Pena-Montes C , Gonzalez A , Castro-Ochoa D , Farres A |
| Ref : Applied Microbiology & Biotechnology , 78 :603 , 2008 |
| Abstract : |
| PubMedSearch : Pena-Montes_2008_Appl.Microbiol.Biotechnol_78_603 |
| PubMedID: 18224318 |
| Title : Characterization of an exported monoglyceride lipase from Mycobacterium tuberculosis possibly involved in the metabolism of host cell membrane lipids - Cotes_2007_Biochem.J_408_417 |
| Author(s) : Cotes K , Dhouib R , Douchet I , Chahinian H , de Caro A , Carriere F , Canaan S |
| Ref : Biochemical Journal , 408 :417 , 2007 |
| Abstract : |
| PubMedSearch : Cotes_2007_Biochem.J_408_417 |
| PubMedID: 17784850 |
| Gene_locus related to this paper: myctu-rv0183 |
| Title : Lipase-catalyzed reactions at different surfaces - Reis_2006_Langmuir_22_8169 |
| Author(s) : Reis P , Holmberg K , Debeche T , Folmer B , Fauconnot L , Watzke H |
| Ref : Langmuir , 22 :8169 , 2006 |
| Abstract : |
| PubMedSearch : Reis_2006_Langmuir_22_8169 |
| PubMedID: 16952258 |
| Title : Synthesis of monocaprin catalyzed by lipase - Da Silva_2003_Appl.Biochem.Biotechnol_105-108_757 |
| Author(s) : da Silva MA , Medeiros VC , Langone MA , Freire DM |
| Ref : Appl Biochem Biotechnol , 105 -108 :757 , 2003 |
| Abstract : |
| PubMedSearch : Da Silva_2003_Appl.Biochem.Biotechnol_105-108_757 |
| PubMedID: 12721413 |