| Title : Gene therapy ameliorates bowel dysmotility and enteric neuron degeneration and extends survival in lysosomal storage disorder mouse models - Ziolkowska_2025_Sci.Transl.Med_17_eadj1445 |
| Author(s) : Ziolkowska EA , Jansen MJ , Williams LL , Wang SH , Eultgen EM , Takahashi K , Le SQ , Nelvagal HR , Sharma J , Sardiello M , DeBosch BJ , Dickson PI , Anderson JB , Sax SE , Wright CM , Bradley RP , Whiteman IT , Makita T , Grider JR , Sands MS , Heuckeroth RO , Cooper JD |
| Ref : Sci Transl Med , 17 :eadj1445 , 2025 |
| Abstract : |
| PubMedSearch : Ziolkowska_2025_Sci.Transl.Med_17_eadj1445 |
| PubMedID: 39813314 |
| Gene_locus related to this paper: mouse-ppt , human-PPT1 |
| Title : Cholinergic crisis in Lycoris radiata poisoning: A case of delayed onset and prolonged symptoms - Tsushima_2025_Am.J.Emerg.Med__ |
| Author(s) : Tsushima R , Satoh F , Sasaki C , Yamagata H , Nogaki A , Takahashi K |
| Ref : Am J Emerg Med , : , 2025 |
| Abstract : |
| PubMedSearch : Tsushima_2025_Am.J.Emerg.Med__ |
| PubMedID: 39904636 |
| Title : Ester derivatives of Dictyostelium differentiation-inducing factors exhibit antibacterial activity, possibly via a prodrug-like function - Takahashi_2025_BMC.Res.Notes_18_40 |
| Author(s) : Takahashi K , Kikuchi H , Nishimura T , Ishigaki H , Miura Y , Takahashi A , Kubohara Y |
| Ref : BMC Res Notes , 18 :40 , 2025 |
| Abstract : |
| PubMedSearch : Takahashi_2025_BMC.Res.Notes_18_40 |
| PubMedID: 39875997 |
| Title : Functional roles and localization of hydrolases in the Japanese mitten crab Eriocheir japonica - Takahashi_2023_Comp.Biochem.Physiol.B.Biochem.Mol.Biol_270_110932 |
| Author(s) : Takahashi M , Takahashi K , Yamaguchi T , Kohama T , Hosokawa M |
| Ref : Comparative Biochemistry & Physiology B Biochem Mol Biol , 270 :110932 , 2023 |
| Abstract : |
| PubMedSearch : Takahashi_2023_Comp.Biochem.Physiol.B.Biochem.Mol.Biol_270_110932 |
| PubMedID: 38097062 |
| Title : Glycaemic control efficacy of switching from dipeptidyl peptidase-4 inhibitors to oral semaglutide in subjects with type 2 diabetes: A multicentre, prospective, randomized, open-label, parallel-group comparison study (SWITCH-SEMA 2 study) - Furusawa_2023_Diabetes.Obes.Metab__ |
| Author(s) : Furusawa S , Nomoto H , Yokoyama H , Suzuki Y , Tsuzuki A , Takahashi K , Miya A , Kameda H , Cho KY , Takeuchi J , Nagai S , Taneda S , Kurihara Y , Nakamura A , Atsumi T |
| Ref : Diabetes Obes Metab , : , 2023 |
| Abstract : |
| PubMedSearch : Furusawa_2023_Diabetes.Obes.Metab__ |
| PubMedID: 38073422 |
| Title : Donepezil prevents olfactory dysfunction and alpha-synuclein aggregation in the olfactory bulb by enhancing autophagy in zinc sulfate-treated mice - Takahashi_2022_Behav.Brain.Res__114175 |
| Author(s) : Takahashi K , Tsuji M , Nakagawasai O , Katsuyama S , Hong L , Miyagawa K , Kurokawa K , Mochida-Saito A , Takeda H , Tadano T |
| Ref : Behavioural Brain Research , :114175 , 2022 |
| Abstract : |
| PubMedSearch : Takahashi_2022_Behav.Brain.Res__114175 |
| PubMedID: 36309244 |
| Title : Crystal structure and substrate recognition mechanism of the prolyl endoprotease PEP from Aspergillus niger - Miyazono_2022_Biochem.Biophys.Res.Commun_591_76 |
| Author(s) : Miyazono KI , Kubota K , Takahashi K , Tanokura M |
| Ref : Biochemical & Biophysical Research Communications , 591 :76 , 2022 |
| Abstract : |
| PubMedSearch : Miyazono_2022_Biochem.Biophys.Res.Commun_591_76 |
| PubMedID: 34999257 |
| Gene_locus related to this paper: aspnc-a2qr21 |
| Title : Activation of cholinergic system partially rescues olfactory dysfunction-induced learning and memory deficit in mice - Takahashi_2021_Behav.Brain.Res__113283 |
| Author(s) : Takahashi K , Tsuji M , Nakagawasai O , Katsuyama S , Miyagawa K , Kurokawa K , Mochida-Saito A , Iwasa M , Iwasa H , Takeda H , Tadano T |
| Ref : Behavioural Brain Research , :113283 , 2021 |
| Abstract : |
| PubMedSearch : Takahashi_2021_Behav.Brain.Res__113283 |
| PubMedID: 33819530 |
| Title : Autism-associated variants of neuroligin 4X impair synaptogenic activity by various molecular mechanisms - Yumoto_2020_Mol.Autism_11_68 |
| Author(s) : Yumoto T , Kimura M , Nagatomo R , Sato T , Utsunomiya S , Aoki N , Kitaura M , Takahashi K , Takemoto H , Watanabe H , Okano H , Yoshida F , Nao Y , Tomita T |
| Ref : Mol Autism , 11 :68 , 2020 |
| Abstract : |
| PubMedSearch : Yumoto_2020_Mol.Autism_11_68 |
| PubMedID: 32873342 |
| Title : Ingestion of difructose anhydride III partially suppresses the deconjugation and 7alpha-dehydroxylation of bile acids in rats fed with a cholic acid-supplemented diet - Lee_2019_Biosci.Biotechnol.Biochem__1 |
| Author(s) : Lee DG , Hori S , Kohmoto O , Kitta S , Yoshida R , Tanaka Y , Shimizu H , Takahashi K , Nagura T , Uchino H , Fukiya S , Yokota A , Ishizuka S |
| Ref : Biosci Biotechnol Biochem , :1 , 2019 |
| Abstract : |
| PubMedSearch : Lee_2019_Biosci.Biotechnol.Biochem__1 |
| PubMedID: 30912732 |
| Title : Leptin in hippocampus mediates benefits of mild exercise by an antioxidant on neurogenesis and memory - Yook_2019_Proc.Natl.Acad.Sci.U.S.A_116_10988 |
| Author(s) : Yook JS , Rakwal R , Shibato J , Takahashi K , Koizumi H , Shima T , Ikemoto MJ , Oharomari LK , McEwen BS , Soya H |
| Ref : Proc Natl Acad Sci U S A , 116 :10988 , 2019 |
| Abstract : |
| PubMedSearch : Yook_2019_Proc.Natl.Acad.Sci.U.S.A_116_10988 |
| PubMedID: 31085646 |
| Title : A bio-image sensor for simultaneous detection of multi-neurotransmitters - Lee_2018_Talanta_179_569 |
| Author(s) : Lee YN , Okumura K , Horio T , Iwata T , Takahashi K , Hattori T , Sawada K |
| Ref : Talanta , 179 :569 , 2018 |
| Abstract : |
| PubMedSearch : Lee_2018_Talanta_179_569 |
| PubMedID: 29310276 |
| Title : Chemical Landscape for Tissue Clearing Based on Hydrophilic Reagents - Tainaka_2018_Cell.Rep_24_2196 |
| Author(s) : Tainaka K , Murakami TC , Susaki EA , Shimizu C , Saito R , Takahashi K , Hayashi-Takagi A , Sekiya H , Arima Y , Nojima S , Ikemura M , Ushiku T , Shimizu Y , Murakami M , Tanaka KF , Iino M , Kasai H , Sasaoka T , Kobayashi K , Miyazono K , Morii E , Isa T , Fukayama M , Kakita A , Ueda HR |
| Ref : Cell Rep , 24 :2196 , 2018 |
| Abstract : |
| PubMedSearch : Tainaka_2018_Cell.Rep_24_2196 |
| PubMedID: 30134179 |
| Title : 123I-iomazenil whole-body imaging to detect hepatic carboxylesterase drug-metabolizing enzyme activity - Mizutani_2018_Nucl.Med.Commun_39_825 |
| Author(s) : Mizutani A , Kobayashi M , Fujita KI , Takahashi K , Hokama T , Takasu H , Nishi K , Nishii R , Shikano N , Fukuchi K , Kawai K |
| Ref : Nucl Med Commun , 39 :825 , 2018 |
| Abstract : |
| PubMedSearch : Mizutani_2018_Nucl.Med.Commun_39_825 |
| PubMedID: 29877992 |
| Title : Production of a Health-Beneficial Food Emulsifier by Enzymatic Partial Hydrolysis of Phospholipids Obtained from the Head of Autumn Chum Salmon - Shah_2017_J.Oleo.Sci_66_147 |
| Author(s) : Shah AK , Nagao T , Kurihara H , Takahashi K |
| Ref : J Oleo Sci , 66 :147 , 2017 |
| Abstract : |
| PubMedSearch : Shah_2017_J.Oleo.Sci_66_147 |
| PubMedID: 28100887 |
| Title : Platelet transfusion improves liver function in patients with chronic liver disease and cirrhosis - Maruyama_2013_Tohoku.J.Exp.Med_229_213 |
| Author(s) : Maruyama T , Murata S , Takahashi K , Tamura T , Nozaki R , Ikeda N , Fukunaga K , Oda T , Sasaki R , Ohkohchi N |
| Ref : Tohoku J Exp Med , 229 :213 , 2013 |
| Abstract : |
| PubMedSearch : Maruyama_2013_Tohoku.J.Exp.Med_229_213 |
| PubMedID: 23459612 |
| Title : Pralidoxime inhibits paraoxon-induced depression of rocuronium-neuromuscular block in a time-dependent fashion - Narimatsu_2012_Am.J.Emerg.Med_30_901 |
| Author(s) : Narimatsu E , Niiya T , Takahashi K , Yamauchi M , Yamakage M |
| Ref : Am J Emerg Med , 30 :901 , 2012 |
| Abstract : |
| PubMedSearch : Narimatsu_2012_Am.J.Emerg.Med_30_901 |
| PubMedID: 21871755 |
| Title : Ectopic expression of an esterase, which is a candidate for the unidentified plant cutinase, causes cuticular defects in Arabidopsis thaliana - Takahashi_2010_Plant.Cell.Physiol_51_123 |
| Author(s) : Takahashi K , Shimada T , Kondo M , Tamai A , Mori M , Nishimura M , Hara-Nishimura I |
| Ref : Plant Cell Physiol , 51 :123 , 2010 |
| Abstract : |
| PubMedSearch : Takahashi_2010_Plant.Cell.Physiol_51_123 |
| PubMedID: 19996150 |
| Title : Blocking histamine H(1) improves learning and mnemonic dysfunction in mice with social isolation plus repeated methamphetamine injection - Jia_2008_J.Pharmacol.Sci_107_167 |
| Author(s) : Jia F , Mobarakeh JI , Dai H , Kato M , Xu A , Okuda T , Sakurai E , Okamura N , Takahashi K , Yanai K |
| Ref : J Pharmacol Sci , 107 :167 , 2008 |
| Abstract : |
| PubMedSearch : Jia_2008_J.Pharmacol.Sci_107_167 |
| PubMedID: 18544893 |
| Title : Cerebral acetylcholinesterase imaging: development of the radioprobes - Kikuchi_2007_Curr.Top.Med.Chem_7_1790 |
| Author(s) : Kikuchi T , Okamura T , Fukushi K , Takahashi K , Toyohara J , Okada M , Zhang MR , Irie T |
| Ref : Curr Top Med Chem , 7 :1790 , 2007 |
| Abstract : |
| PubMedSearch : Kikuchi_2007_Curr.Top.Med.Chem_7_1790 |
| PubMedID: 17979787 |
| Title : Interaction between valproic acid and carbapenem antibiotics - Mori_2007_Drug.Metab.Rev_39_647 |
| Author(s) : Mori H , Takahashi K , Mizutani T |
| Ref : Drug Metabolism Reviews , 39 :647 , 2007 |
| Abstract : |
| PubMedSearch : Mori_2007_Drug.Metab.Rev_39_647 |
| PubMedID: 18058328 |
| Title : Catalytically inactive lipoprotein lipase overexpression increases insulin sensitivity in mice - Shibasaki_2006_Horm.Metab.Res_38_491 |
| Author(s) : Shibasaki M , Bujo H , Takahashi K , Murakami K , Unoki H , Saito Y |
| Ref : Hormone & Metabolic Research , 38 :491 , 2006 |
| Abstract : |
| PubMedSearch : Shibasaki_2006_Horm.Metab.Res_38_491 |
| PubMedID: 16941273 |
| Title : Interfacial behavior of fatty-acylated sericin prepared by lipase-catalyzed solid-phase synthesis - Ogino_2006_Biosci.Biotechnol.Biochem_70_66 |
| Author(s) : Ogino M , Tanaka R , Hattori M , Yoshida T , Yokote Y , Takahashi K |
| Ref : Biosci Biotechnol Biochem , 70 :66 , 2006 |
| Abstract : |
| PubMedSearch : Ogino_2006_Biosci.Biotechnol.Biochem_70_66 |
| PubMedID: 16428822 |
| Title : Mutational analysis of a feruloyl esterase from Aspergillus awamori involved in substrate discrimination and pH dependence - Koseki_2005_Biochim.Biophys.Acta_1722_200 |
| Author(s) : Koseki T , Takahashi K , Fushinobu S , Iefuji H , Iwano K , Hashizume K , Matsuzawa H |
| Ref : Biochimica & Biophysica Acta , 1722 :200 , 2005 |
| Abstract : |
| PubMedSearch : Koseki_2005_Biochim.Biophys.Acta_1722_200 |
| PubMedID: 15716038 |
| Gene_locus related to this paper: aspaw-AXE1 |
| Title : Expression of Ndrg2 in the rat frontal cortex after antidepressant and electroconvulsive treatment - Takahashi_2005_Int.J.Neuropsychopharmacol_8_381 |
| Author(s) : Takahashi K , Yamada M , Ohata H , Momose K , Higuchi T , Honda K |
| Ref : Int J Neuropsychopharmacol , 8 :381 , 2005 |
| Abstract : |
| PubMedSearch : Takahashi_2005_Int.J.Neuropsychopharmacol_8_381 |
| PubMedID: 15769300 |
| Gene_locus related to this paper: ratno-NDRG2 |
| Title : Ndrg2 promotes neurite outgrowth of NGF-differentiated PC12 cells - Takahashi_2005_Neurosci.Lett_388_157 |
| Author(s) : Takahashi K , Yamada M , Ohata H , Honda K |
| Ref : Neuroscience Letters , 388 :157 , 2005 |
| Abstract : |
| PubMedSearch : Takahashi_2005_Neurosci.Lett_388_157 |
| PubMedID: 16039777 |
| Gene_locus related to this paper: ratno-NDRG2 |
| Title : Genetic polymorphisms of the multidrug resistance-associated protein 2 gene (ABCC2) and Irinotecan toxicity - Kitagawa_2004_J.Clin.Oncol_22_2009 |
| Author(s) : Kitagawa C , Ando M , Ando Y , Sekido Y , Usui M , Takahashi K , Shimokata K , Hasegawa Y |
| Ref : J Clin Oncol , 22 :2009 , 2004 |
| Abstract : |
| PubMedSearch : Kitagawa_2004_J.Clin.Oncol_22_2009 |
| PubMedID: 28015787 |
| Title : Mutations in Japanese subjects with primary hyperlipidemia--results from the Research Committee of the Ministry of Health and Welfare of Japan since 1996 - Maruyama_2004_J.Atheroscler.Thromb_11_131 |
| Author(s) : Maruyama T , Yamashita S , Matsuzawa Y , Bujo H , Takahashi K , Saito Y , Ishibashi S , Ohashi K , Shionoiri F , Gotoda T , Yamada N , Kita T |
| Ref : J Atheroscler Thromb , 11 :131 , 2004 |
| Abstract : |
| PubMedSearch : Maruyama_2004_J.Atheroscler.Thromb_11_131 |
| PubMedID: 15256764 |
| Title : Biological evaluation of sphingomyelin analogues as inhibitors of sphingomyelinase - Taguchi_2003_Bioorg.Med.Chem.Lett_13_3681 |
| Author(s) : Taguchi M , Goda K , Sugimoto K , Akama T , Yamamoto K , Suzuki T , Tomishima Y , Nishiguchi M , Arai K , Takahashi K , Kobori T |
| Ref : Bioorganic & Medicinal Chemistry Lett , 13 :3681 , 2003 |
| Abstract : |
| PubMedSearch : Taguchi_2003_Bioorg.Med.Chem.Lett_13_3681 |
| PubMedID: 14552757 |
| Title : Mechanism of 7,12-dimethylbenz[a]anthracene-induced immunotoxicity: role of metabolic activation at the target organ - Miyata_2001_Jpn.J.Pharmacol_86_302 |
| Author(s) : Miyata M , Furukawa M , Takahashi K , Gonzalez FJ , Yamazoe Y |
| Ref : Japanese Journal of Pharmacology , 86 :302 , 2001 |
| Abstract : |
| PubMedSearch : Miyata_2001_Jpn.J.Pharmacol_86_302 |
| PubMedID: 11488430 |
| Title : Evaluation of PET ligands (+)N-[(11)C]ethyl-3-piperidyl benzilate and (+)N-[(11)C]propyl-3-piperidyl benzilate for muscarinic cholinergic receptors: a PET study with microdialysis in comparison with (+)N-[(11)C]methyl-3-piperidyl benzilate in the conscious monkey brain - Nishiyama_2001_Synapse_40_159 |
| Author(s) : Nishiyama S , Tsukada H , Sato K , Kakiuchi T , Ohba H , Harada N , Takahashi K |
| Ref : Synapse , 40 :159 , 2001 |
| Abstract : |
| PubMedSearch : Nishiyama_2001_Synapse_40_159 |
| PubMedID: 11304753 |
| Title : Identification of the cleavage sites of oxidized protein that are susceptible to oxidized protein hydrolase (OPH) in the primary and tertiary structures of the protein - Fujino_2000_J.Biochem.(Tokyo)_127_1087 |
| Author(s) : Fujino T , Kojima M , Beppu M , Kikugawa K , Yasuda H , Takahashi K |
| Ref : J Biochem (Tokyo) , 127 :1087 , 2000 |
| Abstract : |
| PubMedSearch : Fujino_2000_J.Biochem.(Tokyo)_127_1087 |
| PubMedID: 10833279 |
| Title : Properties of a Poly(3-hydroxybutyrate) Depolymerase from Penicillium funiculosum - Miyazaki_2000_J.Polym.Environ_8_175 |
| Author(s) : Miyazaki S , Takahashi K , Shiraki M , Saito T , Tezuka Y , Kasuya KI |
| Ref : J. Polym. Environ , 8 :175 , 2000 |
| Abstract : |
| PubMedSearch : Miyazaki_2000_J.Polym.Environ_8_175 |
| PubMedID: |
| Gene_locus related to this paper: penfu-PHAZ |
| Title : Purification and characterization of two isoforms of serine proteinase from the microsomal membranes of rat liver - Tamanoue_1993_J.Biochem_113_229 |
| Author(s) : Tamanoue Y , Takahashi T , Takahashi K |
| Ref : J Biochem , 113 :229 , 1993 |
| Abstract : |
| PubMedSearch : Tamanoue_1993_J.Biochem_113_229 |
| PubMedID: 8468329 |
| Title : The nucleotide and deduced amino acid sequences of porcine liver proline- beta-naphthylamidase. Evidence for the identity with carboxylesterase - Matsushima_1991_FEBS.Lett_293_37 |
| Author(s) : Matsushima M , Inoue H , Ichinose M , Tsukada S , Miki K , Kurokawa K , Takahashi T , Takahashi K |
| Ref : FEBS Letters , 293 :37 , 1991 |
| Abstract : |
| PubMedSearch : Matsushima_1991_FEBS.Lett_293_37 |
| PubMedID: 1959668 |
| Gene_locus related to this paper: pig-EST1 |
| Title : Ester synthesis at extraordinarily low temperature of -3 degrees C by modified lipase in benzene - Takahashi_1985_Biochem.Int_10_627 |
| Author(s) : Takahashi K , Yoshimoto T , Tamaura Y , Saito Y , Inada Y |
| Ref : Biochemistry International , 10 :627 , 1985 |
| Abstract : |
| PubMedSearch : Takahashi_1985_Biochem.Int_10_627 |
| PubMedID: 3927919 |
| Title : Ester synthesis catalyzed by polyethylene glycol-modified lipase in benzene - Inada_1984_Biochem.Biophys.Res.Commun_122_845 |
| Author(s) : Inada Y , Nishimura H , Takahashi K , Yoshimoto T , Saha AR , Saito Y |
| Ref : Biochemical & Biophysical Research Communications , 122 :845 , 1984 |
| Abstract : |
| PubMedSearch : Inada_1984_Biochem.Biophys.Res.Commun_122_845 |
| PubMedID: 6431976 |
| Title : Effect of light on the acetylcholine concentrations of the suprachiasmatic nucleus in the rat - Murakami_1984_Brain.Res_311_358 |
| Author(s) : Murakami N , Takahashi K , Kawashima K |
| Ref : Brain Research , 311 :358 , 1984 |
| Abstract : |
| PubMedSearch : Murakami_1984_Brain.Res_311_358 |
| PubMedID: 6541956 |
| Title : A study of the novel synthetic analog (+\/-)-depentylperhydrohistrionicotoxin on the nicotinic receptor-ion channel complex - Maleque_1984_J.Pharmacol.Exp.Ther_230_619 |
| Author(s) : Maleque MA , Takahashi K , Witkop B , Brossi A , Albuquerque EX |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 230 :619 , 1984 |
| Abstract : |
| PubMedSearch : Maleque_1984_J.Pharmacol.Exp.Ther_230_619 |
| PubMedID: 6088758 |
| Title : The ionic channel of the nicotinic acetylcholine receptor is unable to differentiate between the optical antipodes of perhydrohistrionicotoxin - Spivak_1983_FEBS.Lett_163_189 |
| Author(s) : Spivak CE , Maleque MA , Takahashi K , Brossi A , Albuquerque EX |
| Ref : FEBS Letters , 163 :189 , 1983 |
| Abstract : |
| PubMedSearch : Spivak_1983_FEBS.Lett_163_189 |
| PubMedID: 6315487 |
| Title : (+\/-)-2-Depentylperhydrohistrionicotoxin: a new probe for a regulatory site on the nicotinic acetylcholine receptor-channel - Takahashi_1982_J.Med.Chem_25_919 |
| Author(s) : Takahashi K , Jacobson AE , Mak CP , Witkop B , Brossi A , Albuquerque EX , Warnick JE , Maleque MA , Bavoso A , Silverton JV |
| Ref : Journal of Medicinal Chemistry , 25 :919 , 1982 |
| Abstract : |
| PubMedSearch : Takahashi_1982_J.Med.Chem_25_919 |
| PubMedID: 6288946 |