Gene_Locus Report

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Gene_locus Report for: brume-BMEI1608

Brucella melitensis, Brucella suis, Brucella abortus, Brucella ceti, B. pinnipedialis, B. microti, B. canis, B. ovis, B. inopinata, proline iminopeptidase (EC 3.4.11.5)

Comment
Brucella pinnipedialis (B2/94; M163/99/10; M292/94/1), Brucella melitensis (bv. 1 Rev.1; bv. 2 63/9; biotype 1 16M / ATCC 23456 / NCTC 10094; M28; bv. 3 Ether; M5-90; biotype 2 ATCC 23457), Brucella ceti (Cudo; B1/94; M13/05/1; M490/95/1; M644/93/1), Brucella abortus (S19; bv. 5 B3196; NCTC 8038; bv. 3 Tulya; bv. 2 86/8/59; bv. 9 C68; bv. 6 870; 2308 A; bv. 4 292), Brucella suis (ATCC 23445 / NCTC 10510; bv. 5 513; biovar 1 1330;bv. 4 40; bv. 3 686), Brucella sp. (F5/99; 83/13; NVSL 07-0026; NF 2653; BO2), Brucella microti (CCM 4915), Brucella neotomae 5K33, Brucella canis (ATCC 23365 / NCTC 10854), Brucella ovis (ATCC 25840 / 63/290 / NCTC 10512), Brucella inopinata BO1


Relationship
Family|Proline_iminopeptidase
Block| X
Position in NCBI Life Tree|Brucella melitensis
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Bacteria: N E > Proteobacteria: N E > Alphaproteobacteria: N E > Rhizobiales: N E > Brucellaceae: N E > Brucella: N E > Brucella melitensis: N E
Warning: This entry is a compilation of different species or line or strain with more than 90% amino acid identity. You can retrieve all strain data


Molecular evidence
Database
No mutation
No structure
No kinetic





No Substrate
No inhibitor
>3 Genbank links 1 more: AE009596, AE014343, AE017223
>3 UniProt links 22 more: Q8YFB4, Q57F44, Q2YPG0
>3 UniProt links 22 more: Q8YFB4, Q57F44, Q2YPG0
>3 Interpro links 22 more: Q8YFB4, Q57F44, Q2YPG0
>3 Pfam links 22 more: Q8YFB4, Q57F44, Q2YPG0
>3 PIRSF links 22 more: Q8YFB4, Q57F44, Q2YPG0
>3 SUPERFAM links 22 more: Q8YFB4, Q57F44, Q2YPG0
Sequence
Graphical view for this peptide sequence: brume-BMEI1608
Colored MSA for Proline_iminopeptidase (raw)
MTHHRNATGGPILPAEGNKRHFMTRNTLYPEIEPFKEEMLQVSSLHRIHV
EQCGNPDGKPVIMIHGGPGGGITPTMRRLHDPKRYRIILFDQRGCGRSTP
HAELRENTTWDLVADMEHIRAHLGIDKWQVFGGSWGSTLGLAYAETHPER
VSELVLRGIFMVRRFEVDWMYSNGASIIFPDHFEAYQEHIPEAERGDMIA
AYYKRLTDRDPRVQLEAARRWARWEGSVISLLPDPARVDAFGEDQYAIAF
ARIECHYFQNRGFLESDDQLLRNVERIRHIPGVIVHGRYDICTPFINAWQ
LKKMWPEADLKIVEDSGHAVTEPGIMHELIEATKRFCE
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

MTHHRNATGGPILPAEGNKRHFMTRNTLYPEIEPFKEEMLQVSSLHRIHV
EQCGNPDGKPVIMIHGGPGGGITPTMRRLHDPKRYRIILFDQRGCGRSTP
HAELRENTTWDLVADMEHIRAHLGIDKWQVFGGSWGSTLGLAYAETHPER
VSELVLRGIFMVRRFEVDWMYSNGASIIFPDHFEAYQEHIPEAERGDMIA
AYYKRLTDRDPRVQLEAARRWARWEGSVISLLPDPARVDAFGEDQYAIAF
ARIECHYFQNRGFLESDDQLLRNVERIRHIPGVIVHGRYDICTPFINAWQ
LKKMWPEADLKIVEDSGHAVTEPGIMHELIEATKRFCE


References
6 more
    Title: Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis
    Halling SM, Peterson-Burch BD, Bricker BJ, Zuerner RL, Qing Z, Li LL, Kapur V, Alt DP, Olsen SC
    Ref: Journal of Bacteriology, 187:2715, 2005 : PubMed

            

    Title: The genome sequence of the facultative intracellular pathogen Brucella melitensis
    DelVecchio VG, Kapatral V, Redkar RJ, Patra G, Mujer C, Los T, Ivanova N, Anderson I, Bhattacharyya A and Overbeek R <15 more author(s)>
    Ref: Proc Natl Acad Sci U S A, 99:443, 2002 : PubMed

            

    Title: The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts
    Paulsen IT, Seshadri R, Nelson KE, Eisen JA, Heidelberg JF, Read TD, Dodson RJ, Umayam L, Brinkac LM and Fraser CM <21 more author(s)>
    Ref: Proc Natl Acad Sci U S A, 99:13148, 2002 : PubMed

            


Other Papers


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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