Steroid

A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration. Steroids have two principal biological functions: as important components of cell membranes which alter membrane fluidity\; and as signaling molecules. Steroids ae not normaly targets of alpha\/beta hydrolases but esters and derivatives can be inhibitors or substrates of some enzymes in the family
Substrate Main targeted enzyme families Type Structure
Linolenic-acid-stigmasterol-ester Fungal-Bact_LIP Steroid Fatty acid ester Phenanthrene Water-insoluble medium and long chain ester
Beclomethasone-dipropionate Arylacetamide_deacetylase Drug Pro-Drug Not AlphaBeta Hydrolase target Steroid Propionate Phenanthrene Organochlorine
Cholesterol PC-sterol_acyltransferase Bacterial_lip_FamI.6 Natural Steroid Phenanthrene
Cholesterol-acetate Steryl_acetyl_hydrolase Hormone-sensitive_lipase_like Cholesterylester Steroid Acetate Phenanthrene
Methylprednisolone-acetate BCHE Acetate Steroid Phenanthrene Drug
Cholesteryl-linoleate Fungal_carboxylesterase_lipase Cholesterylester Steroid Phenanthrene Linoleate
Cholesteryl-oleate Carboxylesterase Acidic_Lipase Carb_B_Chordata Hormone-sensitive_lipase_like Cholesterol_esterase LIDHydrolase Fungal_carboxylesterase_lipase Arylacetamide_deacetylase Cholesterylester Steroid Oleate Phenanthrene
Linolenic-acid-stigmasterol-ester Fungal-Bact_LIP Steroid Fatty acid ester Phenanthrene Water-insoluble medium and long chain ester
Beclomethasone-dipropionate Arylacetamide_deacetylase Drug Pro-Drug Not AlphaBeta Hydrolase target Steroid Propionate Phenanthrene Organochlorine
Cholesterol PC-sterol_acyltransferase Bacterial_lip_FamI.6 Natural Steroid Phenanthrene
Cholesterol-acetate Steryl_acetyl_hydrolase Hormone-sensitive_lipase_like Cholesterylester Steroid Acetate Phenanthrene
Methylprednisolone-acetate BCHE Acetate Steroid Phenanthrene Drug
Cholesteryl-linoleate Fungal_carboxylesterase_lipase Cholesterylester Steroid Phenanthrene Linoleate
Cholesteryl-oleate Carboxylesterase Acidic_Lipase Carb_B_Chordata Hormone-sensitive_lipase_like Cholesterol_esterase LIDHydrolase Fungal_carboxylesterase_lipase Arylacetamide_deacetylase Cholesterylester Steroid Oleate Phenanthrene
Linolenic-acid-stigmasterol-ester Fungal-Bact_LIP Steroid Fatty acid ester Phenanthrene Water-insoluble medium and long chain ester
Beclomethasone-dipropionate Arylacetamide_deacetylase Drug Pro-Drug Not AlphaBeta Hydrolase target Steroid Propionate Phenanthrene Organochlorine
Cholesterol PC-sterol_acyltransferase Bacterial_lip_FamI.6 Natural Steroid Phenanthrene
Cholesterol-acetate Steryl_acetyl_hydrolase Hormone-sensitive_lipase_like Cholesterylester Steroid Acetate Phenanthrene
Methylprednisolone-acetate BCHE Acetate Steroid Phenanthrene Drug
Cholesteryl-linoleate Fungal_carboxylesterase_lipase Cholesterylester Steroid Phenanthrene Linoleate
Cholesteryl-oleate Carboxylesterase Acidic_Lipase Carb_B_Chordata Hormone-sensitive_lipase_like Cholesterol_esterase LIDHydrolase Fungal_carboxylesterase_lipase Arylacetamide_deacetylase Cholesterylester Steroid Oleate Phenanthrene