Wehle S

General

Full name : Wehle Sarah

First name : Sarah

Mail : Pharmaceutical and Medicinal Chemistry, Institute of Pharmacy and Food Chemistry, Julius-Maximilians-University Wurzburg, Am Hubland, D97074 Wurzburg

Zip Code :

City :

Country : Germany

Email : sarah.wehle@uni-wuerzburg.de

Phone :

Fax :

Website :

Directory :

References (6)

Title : Synthesis and Biological Assessment of Racemic Benzochromenopyrimidinimines as Antioxidant, Cholinesterase, and Abeta1-42 Aggregation Inhibitors for Alzheimer's Disease Therapy - Dgachi_2016_ChemMedChem_11_1318
Author(s) : Dgachi Y , Ismaili L , Knez D , Benchekroun M , Martin H , Szalaj N , Wehle S , Bautista-Aguilera OM , Luzet V , Bonnet A , Malawska B , Gobec S , Chioua M , Decker M , Chabchoub F , Marco-Contelles J
Ref : ChemMedChem , 11 :1318 , 2016
Abstract :
PubMedSearch : Dgachi_2016_ChemMedChem_11_1318
PubMedID: 26804623

Title : Discovery of Highly Selective and Nanomolar Carbamate-Based Butyrylcholinesterase Inhibitors by Rational Investigation into Their Inhibition Mode - Sawatzky_2016_J.Med.Chem_59_2067
Author(s) : Sawatzky E , Wehle S , Kling B , Wendrich J , Bringmann G , Sotriffer CA , Heilmann J , Decker M
Ref : Journal of Medicinal Chemistry , 59 :2067 , 2016
Abstract :
PubMedSearch : Sawatzky_2016_J.Med.Chem_59_2067
PubMedID: 26886849

Title : Novel tacrine-grafted ugi adducts as multipotent anti-Alzheimer drugs: a synthetic renewal in tacrine-ferulic Acid hybrids - Benchekroun_2015_ChemMedChem_10_523
Author(s) : Benchekroun M , Bartolini M , Egea J , Romero A , Soriano E , Pudlo M , Luzet V , Andrisano V , Jimeno ML , Lopez MG , Wehle S , Gharbi T , Refouvelet B , de Andres L , Herrera-Arozamena C , Monti B , Bolognesi ML , Rodriguez-Franco MI , Decker M , Marco-Contelles J , Ismaili L
Ref : ChemMedChem , 10 :523 , 2015
Abstract :
PubMedSearch : Benchekroun_2015_ChemMedChem_10_523
PubMedID: 25537267

Title : Amine substitution of quinazolinones leads to selective nanomolar AChE inhibitors with 'inverted' binding mode - Darras_2014_Bioorg.Med.Chem_22_4867
Author(s) : Darras FH , Wehle S , Huang G , Sotriffer CA , Decker M
Ref : Bioorganic & Medicinal Chemistry , 22 :4867 , 2014
Abstract :
PubMedSearch : Darras_2014_Bioorg.Med.Chem_22_4867
PubMedID: 25047936

Title : Synthesis, Biological Evaluation, and Computational Studies of Tri- and Tetracyclic Nitrogen-Bridgehead Compounds as Potent Dual-Acting AChE Inhibitors and hH3 Receptor Antagonists - Darras_2014_ACS.Chem.Neurosci_5_225
Author(s) : Darras FH , Pockes S , Huang G , Wehle S , Strasser A , Wittmann HJ , Nimczick M , Sotriffer CA , Decker M
Ref : ACS Chem Neurosci , 5 :225 , 2014
Abstract :
PubMedSearch : Darras_2014_ACS.Chem.Neurosci_5_225
PubMedID: 24422467

Title : Acetylcholinesterase inhibitors with photoswitchable inhibition of beta-amyloid aggregation - Chen_2014_ACS.Chem.Neurosci_5_377
Author(s) : Chen X , Wehle S , Kuzmanovic N , Merget B , Holzgrabe U , Konig B , Sotriffer CA , Decker M
Ref : ACS Chem Neurosci , 5 :377 , 2014
Abstract :
PubMedSearch : Chen_2014_ACS.Chem.Neurosci_5_377
PubMedID: 24628027