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| Title : Enzymatic and solid-phase synthesis of new donepezil-based L- and d-glutamic acid derivatives and their pharmacological evaluation in models related to Alzheimer's disease and cerebral ischemia - Monjas_2017_Eur.J.Med.Chem_130_60 |
| Author(s) : Monjas L , Arce MP , Leon R , Egea J , Perez C , Villarroya M , Lopez MG , Gil C , Conde S , Rodriguez-Franco MI |
| Ref : Eur Journal of Medicinal Chemistry , 130 :60 , 2017 |
| Abstract : Monjas_2017_Eur.J.Med.Chem_130_60 |
| ESTHER : Monjas_2017_Eur.J.Med.Chem_130_60 |
| PubMedSearch : Monjas_2017_Eur.J.Med.Chem_130_60 |
| PubMedID: 28242552 |
| Title : New melatonin-N,N-dibenzyl(N-methyl)amine hybrids: potent neurogenic agents with antioxidant, cholinergic, and neuroprotective properties as innovative drugs for Alzheimer's disease - Lopez-Iglesias_2014_J.Med.Chem_57_3773 |
| Author(s) : Lopez-Iglesias B , Perez C , Morales-Garcia JA , Alonso-Gil S , Perez-Castillo A , Romero A , Lopez MG , Villarroya M , Conde S , Rodriguez-Franco MI |
| Ref : Journal of Medicinal Chemistry , 57 :3773 , 2014 |
| Abstract : Lopez-Iglesias_2014_J.Med.Chem_57_3773 |
| ESTHER : Lopez-Iglesias_2014_J.Med.Chem_57_3773 |
| PubMedSearch : Lopez-Iglesias_2014_J.Med.Chem_57_3773 |
| PubMedID: 24738476 |
| Title : PP2A ligand ITH12246 protects against memory impairment and focal cerebral ischemia in mice - Lorrio_2013_ACS.Chem.Neurosci_4_1267 |
| Author(s) : Lorrio S , Romero A , Gonzalez-Lafuente L , Lajarin-Cuesta R , Martinez-Sanz FJ , Estrada M , Samadi A , Marco-Contelles J , Rodriguez-Franco MI , Villarroya M , Lopez MG , de los Rios C |
| Ref : ACS Chem Neurosci , 4 :1267 , 2013 |
| Abstract : Lorrio_2013_ACS.Chem.Neurosci_4_1267 |
| ESTHER : Lorrio_2013_ACS.Chem.Neurosci_4_1267 |
| PubMedSearch : Lorrio_2013_ACS.Chem.Neurosci_4_1267 |
| PubMedID: 23763493 |
| Title : N-acylaminophenothiazines: neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease - Gonzalez-Munoz_2011_Eur.J.Med.Chem_46_2224 |
| Author(s) : Gonzalez-Munoz GC , Arce MP , Lopez B , Perez C , Romero A , Del Barrio L , Martin-de-Saavedra MD , Egea J , Leon R , Villarroya M , Lopez MG , Garcia AG , Conde S , Rodriguez-Franco MI |
| Ref : Eur Journal of Medicinal Chemistry , 46 :2224 , 2011 |
| Abstract : Gonzalez-Munoz_2011_Eur.J.Med.Chem_46_2224 |
| ESTHER : Gonzalez-Munoz_2011_Eur.J.Med.Chem_46_2224 |
| PubMedSearch : Gonzalez-Munoz_2011_Eur.J.Med.Chem_46_2224 |
| PubMedID: 21420206 |
| Title : Synthesis and pharmacological assessment of diversely substituted pyrazolo[3,4-b]quinoline, and benzo[b]pyrazolo[4,3-g][1,8]naphthyridine derivatives - Silva_2011_Eur.J.Med.Chem_46_4676 |
| Author(s) : Silva D , Chioua M , Samadi A , Carmo Carreiras M , Jimeno ML , Mendes E , Rios Cde L , Romero A , Villarroya M , Lopez MG , Marco-Contelles J |
| Ref : Eur Journal of Medicinal Chemistry , 46 :4676 , 2011 |
| Abstract : Silva_2011_Eur.J.Med.Chem_46_4676 |
| ESTHER : Silva_2011_Eur.J.Med.Chem_46_4676 |
| PubMedSearch : Silva_2011_Eur.J.Med.Chem_46_4676 |
| PubMedID: 21715067 |
| Title : Old phenothiazine and dibenzothiadiazepine derivatives for tomorrow's neuroprotective therapies against neurodegenerative diseases - Gonzalez-Munoz_2010_Eur.J.Med.Chem_45_6152 |
| Author(s) : Gonzalez-Munoz GC , Arce MP , Lopez B , Perez C , Villarroya M , Lopez MG , Garcia AG , Conde S , Rodriguez-Franco MI |
| Ref : Eur Journal of Medicinal Chemistry , 45 :6152 , 2010 |
| Abstract : Gonzalez-Munoz_2010_Eur.J.Med.Chem_45_6152 |
| ESTHER : Gonzalez-Munoz_2010_Eur.J.Med.Chem_45_6152 |
| PubMedSearch : Gonzalez-Munoz_2010_Eur.J.Med.Chem_45_6152 |
| PubMedID: 20926162 |
| Title : Multipotent drugs with cholinergic and neuroprotective properties for the treatment of Alzheimer and neuronal vascular diseases. I. Synthesis, biological assessment, and molecular modeling of simple and readily available 2-aminopyridine-, and 2-chloropyridine-3,5-dicarbonitriles - Samadi_2010_Bioorg.Med.Chem_18_5861 |
| Author(s) : Samadi A , Marco-Contelles J , Soriano E , Alvarez-Perez M , Chioua M , Romero A , Gonzalez-Lafuente L , Gandia L , Roda JM , Lopez MG , Villarroya M , Garcia AG , Rios Cde L |
| Ref : Bioorganic & Medicinal Chemistry , 18 :5861 , 2010 |
| Abstract : Samadi_2010_Bioorg.Med.Chem_18_5861 |
| ESTHER : Samadi_2010_Bioorg.Med.Chem_18_5861 |
| PubMedSearch : Samadi_2010_Bioorg.Med.Chem_18_5861 |
| PubMedID: 20656495 |
| Title : Synthesis, inhibitory activity of cholinesterases, and neuroprotective profile of novel 1,8-naphthyridine derivatives - de Los Rios_2010_J.Med.Chem_53_5129 |
| Author(s) : de los Rios C , Egea J , Marco-Contelles J , Leon R , Samadi A , Iriepa I , Moraleda I , Galvez E , Garcia AG , Lopez MG , Villarroya M , Romero A |
| Ref : Journal of Medicinal Chemistry , 53 :5129 , 2010 |
| Abstract : de Los Rios_2010_J.Med.Chem_53_5129 |
| ESTHER : de Los Rios_2010_J.Med.Chem_53_5129 |
| PubMedSearch : de Los Rios_2010_J.Med.Chem_53_5129 |
| PubMedID: 20575555 |
| Title : Novel tacrine-8-hydroxyquinoline hybrids as multifunctional agents for the treatment of Alzheimer's disease, with neuroprotective, cholinergic, antioxidant, and copper-complexing properties - Fernandez-Bachiller_2010_J.Med.Chem_53_4927 |
| Author(s) : Fernandez-Bachiller MI , Perez C , Gonzalez-Munoz GC , Conde S , Lopez MG , Villarroya M , Garcia AG , Rodriguez-Franco MI |
| Ref : Journal of Medicinal Chemistry , 53 :4927 , 2010 |
| Abstract : Fernandez-Bachiller_2010_J.Med.Chem_53_4927 |
| ESTHER : Fernandez-Bachiller_2010_J.Med.Chem_53_4927 |
| PubMedSearch : Fernandez-Bachiller_2010_J.Med.Chem_53_4927 |
| PubMedID: 20545360 |
| Title : Tacrine-melatonin hybrids as multifunctional agents for Alzheimer's disease, with cholinergic, antioxidant, and neuroprotective properties - Fernandez-Bachiller_2009_ChemMedChem_4_828 |
| Author(s) : Fernandez-Bachiller MI , Perez C , Campillo NE , Paez JA , Gonzalez-Munoz GC , Usan P , Garcia-Palomero E , Lopez MG , Villarroya M , Garcia AG , Martinez A , Rodriguez-Franco MI |
| Ref : ChemMedChem , 4 :828 , 2009 |
| Abstract : Fernandez-Bachiller_2009_ChemMedChem_4_828 |
| ESTHER : Fernandez-Bachiller_2009_ChemMedChem_4_828 |
| PubMedSearch : Fernandez-Bachiller_2009_ChemMedChem_4_828 |
| PubMedID: 19308922 |
| Title : Neuroprotective and cholinergic properties of multifunctional glutamic acid derivatives for the treatment of Alzheimer's disease - Arce_2009_J.Med.Chem_52_7249 |
| Author(s) : Arce MP , Rodriguez-Franco MI , Gonzalez-Munoz GC , Perez C , Lopez B , Villarroya M , Lopez MG , Garcia AG , Conde S |
| Ref : Journal of Medicinal Chemistry , 52 :7249 , 2009 |
| Abstract : Arce_2009_J.Med.Chem_52_7249 |
| ESTHER : Arce_2009_J.Med.Chem_52_7249 |
| PubMedSearch : Arce_2009_J.Med.Chem_52_7249 |
| PubMedID: 19856923 |
| Title : New tacrine-dihydropyridine hybrids that inhibit acetylcholinesterase, calcium entry, and exhibit neuroprotection properties - Leon_2008_Bioorg.Med.Chem_16_7759 |
| Author(s) : Leon R , de los Rios C , Marco-Contelles J , Huertas O , Barril X , Luque FJ , Lopez MG , Garcia AG , Villarroya M |
| Ref : Bioorganic & Medicinal Chemistry , 16 :7759 , 2008 |
| Abstract : Leon_2008_Bioorg.Med.Chem_16_7759 |
| ESTHER : Leon_2008_Bioorg.Med.Chem_16_7759 |
| PubMedSearch : Leon_2008_Bioorg.Med.Chem_16_7759 |
| PubMedID: 18640842 |
| Title : An update on the pharmacology of galantamine - Villarroya_2007_Expert.Opin.Investig.Drugs_16_1987 |
| Author(s) : Villarroya M , Garcia AG , Marco-Contelles J , Lopez MG |
| Ref : Expert Opin Investig Drugs , 16 :1987 , 2007 |
| Abstract : Villarroya_2007_Expert.Opin.Investig.Drugs_16_1987 |
| ESTHER : Villarroya_2007_Expert.Opin.Investig.Drugs_16_1987 |
| PubMedSearch : Villarroya_2007_Expert.Opin.Investig.Drugs_16_1987 |
| PubMedID: 18042006 |
| Title : Captan and fenitrothion dissipation in field-treated cauliflowers and effect of household processing - Fernandez-Cruz_2006_Pest.Manag.Sci_62_637 |
| Author(s) : Fernandez-Cruz ML , Barreda M , Villarroya M , Peruga A , Llanos S , Garcia-Baudan JM |
| Ref : Pest Manag Sci , 62 :637 , 2006 |
| Abstract : Fernandez-Cruz_2006_Pest.Manag.Sci_62_637 |
| ESTHER : Fernandez-Cruz_2006_Pest.Manag.Sci_62_637 |
| PubMedSearch : Fernandez-Cruz_2006_Pest.Manag.Sci_62_637 |
| PubMedID: 16718745 |
| Title : Novel multipotent tacrine-dihydropyridine hybrids with improved acetylcholinesterase inhibitory and neuroprotective activities as potential drugs for the treatment of Alzheimer's disease - Marco-Contelles_2006_J.Med.Chem_49_7607 |
| Author(s) : Marco-Contelles J , Leon R , de los Rios C , Guglietta A , Terencio J , Lopez MG , Garcia AG , Villarroya M |
| Ref : Journal of Medicinal Chemistry , 49 :7607 , 2006 |
| Abstract : Marco-Contelles_2006_J.Med.Chem_49_7607 |
| ESTHER : Marco-Contelles_2006_J.Med.Chem_49_7607 |
| PubMedSearch : Marco-Contelles_2006_J.Med.Chem_49_7607 |
| PubMedID: 17181144 |
| Title : Synthesis and biological evaluation of new 4H-pyrano[2,3-b]quinoline derivatives that block acetylcholinesterase and cell calcium signals, and cause neuroprotection against calcium overload and free radicals - Marco-Contelles_2006_Eur.J.Med.Chem_41_1464 |
| Author(s) : Marco-Contelles J , Leon R , Lopez MG , Garcia AG , Villarroya M |
| Ref : Eur Journal of Medicinal Chemistry , 41 :1464 , 2006 |
| Abstract : Marco-Contelles_2006_Eur.J.Med.Chem_41_1464 |
| ESTHER : Marco-Contelles_2006_Eur.J.Med.Chem_41_1464 |
| PubMedSearch : Marco-Contelles_2006_Eur.J.Med.Chem_41_1464 |
| PubMedID: 17030484 |
| Title : Unequal neuroprotection afforded by the acetylcholinesterase inhibitors galantamine, donepezil, and rivastigmine in SH-SY5Y neuroblastoma cells: role of nicotinic receptors - Arias_2005_J.Pharmacol.Exp.Ther_315_1346 |
| Author(s) : Arias E , Gallego-Sandin S , Villarroya M , Garcia AG , Lopez MG |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 315 :1346 , 2005 |
| Abstract : Arias_2005_J.Pharmacol.Exp.Ther_315_1346 |
| ESTHER : Arias_2005_J.Pharmacol.Exp.Ther_315_1346 |
| PubMedSearch : Arias_2005_J.Pharmacol.Exp.Ther_315_1346 |
| PubMedID: 16144975 |
| Title : Synthesis, acetylcholinesterase inhibition and neuroprotective activity of new tacrine analogues - Leon_2005_Bioorg.Med.Chem_13_1167 |
| Author(s) : Leon R , Marco-Contelles J , Garcia AG , Villarroya M |
| Ref : Bioorganic & Medicinal Chemistry , 13 :1167 , 2005 |
| Abstract : Leon_2005_Bioorg.Med.Chem_13_1167 |
| ESTHER : Leon_2005_Bioorg.Med.Chem_13_1167 |
| PubMedSearch : Leon_2005_Bioorg.Med.Chem_13_1167 |
| PubMedID: 15670925 |
| Title : Galantamine prevents apoptosis induced by beta-amyloid and thapsigargin: involvement of nicotinic acetylcholine receptors - Arias_2004_Neuropharmacol_46_103 |
| Author(s) : Arias E , Ales E , Gabilan NH , Cano-Abad MF , Villarroya M , Garcia AG , Lopez MG |
| Ref : Neuropharmacology , 46 :103 , 2004 |
| Abstract : Arias_2004_Neuropharmacol_46_103 |
| ESTHER : Arias_2004_Neuropharmacol_46_103 |
| PubMedSearch : Arias_2004_Neuropharmacol_46_103 |
| PubMedID: 14654102 |
| Title : ITH4012 (ethyl 5-amino-6,7,8,9-tetrahydro-2-methyl-4-phenylbenzol[1,8]naphthyridine-3-carboxylat e), a novel acetylcholinesterase inhibitor with calcium promotor and neuroprotective properties - Orozco_2004_J.Pharmacol.Exp.Ther_310_987 |
| Author(s) : Orozco C , de los Rios C , Arias E , Leon R , Garcia AG , Marco JL , Villarroya M , Lopez MG |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 310 :987 , 2004 |
| Abstract : Orozco_2004_J.Pharmacol.Exp.Ther_310_987 |
| ESTHER : Orozco_2004_J.Pharmacol.Exp.Ther_310_987 |
| PubMedSearch : Orozco_2004_J.Pharmacol.Exp.Ther_310_987 |
| PubMedID: 15111641 |
| Title : Synthesis, biological evaluation and molecular modelling of diversely functionalized heterocyclic derivatives as inhibitors of acetylcholinesterase\/butyrylcholinesterase and modulators of Ca2+ channels and nicotinic receptors - Marco_2004_Bioorg.Med.Chem_12_2199 |
| Author(s) : Marco JL , de los Rios C , Garcia AG , Villarroya M , Carreiras MC , Martins C , Eleuterio A , Morreale A , Orozco M , Luque FJ |
| Ref : Bioorganic & Medicinal Chemistry , 12 :2199 , 2004 |
| Abstract : Marco_2004_Bioorg.Med.Chem_12_2199 |
| ESTHER : Marco_2004_Bioorg.Med.Chem_12_2199 |
| PubMedSearch : Marco_2004_Bioorg.Med.Chem_12_2199 |
| PubMedID: 15080920 |
| Title : New classes of AChE inhibitors with additional pharmacological effects of interest for the treatment of Alzheimer's disease - Villarroya_2004_Curr.Pharm.Des_10_3177 |
| Author(s) : Villarroya M , Garcia AG , Marco JL |
| Ref : Curr Pharm Des , 10 :3177 , 2004 |
| Abstract : Villarroya_2004_Curr.Pharm.Des_10_3177 |
| ESTHER : Villarroya_2004_Curr.Pharm.Des_10_3177 |
| PubMedSearch : Villarroya_2004_Curr.Pharm.Des_10_3177 |
| PubMedID: 15544507 |
| Title : Novel tacrine derivatives that block neuronal calcium channels - de los Rios_2002_Bioorg.Med.Chem_10_2077 |
| Author(s) : de los Rios C , Marco JL , Carreiras MD , Chinchon PM , Garcia AG , Villarroya M |
| Ref : Bioorganic & Medicinal Chemistry , 10 :2077 , 2002 |
| Abstract : de los Rios_2002_Bioorg.Med.Chem_10_2077 |
| ESTHER : de los Rios_2002_Bioorg.Med.Chem_10_2077 |
| PubMedSearch : de los Rios_2002_Bioorg.Med.Chem_10_2077 |
| PubMedID: 11937366 |