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plafa-MAL6P1.135

Plasmodium falciparum (isolate 3D7) PF3D7_0629300 Phosphatidylcholine-sterol acyltransferase, putative (EC 2.3.1.43) PfPL

Comment

long region of repeats non homologous in N-term

Relationship

Family : PC-sterol_acyltransferase

Block : L

Position in NCBI Life Tree : Plasmodium falciparum

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Eukaryota N E > Alveolata N E > Apicomplexa N E > Aconoidasida N E > Haemosporida N E > Plasmodiidae N E > Plasmodium N E > Plasmodium (Laverania) N E > Plasmodium falciparum N E

Molecular evidence

No mutation

No structure

No kinetic

No disease

No substrate

No inhibitor

Database

Sequence

Peptide

KPTTYLLPGL GGSTLIAEYK NATIHSCSRY LLNSKPFRIW ISLSRLLSIQ SNIYCTFDTI RLKYDEKKNI YYNQPGVFID VEKFGNLKGI EYLDYFNNTG IGITKYFNVV GQYFTSHGYV DGESIIGAPY DWRYPLSQQN YKILKEHIEY IYEKRNGTKV NLIGHSLGGL YLNFFLSRVV SKKWKQKHLS KIIFISTPFK GSVKTIRALI QSRKDFISFR ITKLIKLSIP ESMMKALGNS LGSLFDILPY REYYKRDQVV ILINMSNTPI DEDHVQYLVT LCGIYKPECY RNRADVNLKV YTLKNWHELL DDKLKAKYEN YKLYRERYYN KDHGVPIYCL YSTINKKETE YLLYFETQNT REEPTIYYGT GDGTVGTESL QACSNFYNTV LTHHFSDTSH VGILYTNETA KYIYDIVESP N

References (4)

Title : Activity-based protein profiling of human and plasmodium serine hydrolases and interrogation of potential antimalarial targets - Davison_2022_iScience_25_104996
Author(s) : Davison D , Howell S , Snijders AP , Deu E
Ref : iScience , 25 :104996 , 2022
Abstract :
PubMedSearch : Davison_2022_iScience_25_104996
PubMedID: 3610559
Gene_locus related to this paper: plafa-MAL6P1.135 , plafa-PF11.0211 , plafa-PF11.0441 , plafa-PF13.0153 , plafa-PF14.0737 , plafa-PF14.0738 , plafa-PFD0185C

Title : Functional annotation of serine hydrolases in the asexual erythrocytic stage of Plasmodium falciparum - Elahi_2019_Sci.Rep_9_17532
Author(s) : Elahi R , Ray WK , Dapper C , Dalal S , Helm RF , Klemba M
Ref : Sci Rep , 9 :17532 , 2019
Abstract :
PubMedSearch : Elahi_2019_Sci.Rep_9_17532
PubMedID: 31772212
Gene_locus related to this paper: plafa-a0a143zya4 , plaf7-c0h4q4 , plaf7-q8i5y6 , plaf7-q8ibz1 , plaf7-q8iik5 , plafa-MAL3P8.11 , plafa-MAL6P1.135 , plafa-MAL7P1.156 , plafa-MAL8P1.38 , plafa-MAL8P1.138 , plafa-PF07.0005 , plafa-PF07.0040 , plafa-PF08.0022 , plafa-PF10.0020 , plafa-PF10.0379 , plafa-PF11.0211 , plafa-PF11.0276 , plafa-PF11.0441 , plafa-PF13.0153 , plafa-PF14.0015 , plafa-w7jws4 , plafa-PF14.0017 , plafa-PF14.0099 , plafa-PF14.0250 , plafa-PF14.0395 , plafa-PF14.0737 , plafa-PF14.0738 , plafa-PFC0950C , plafa-PFD0185C , plafa-PFI1775W , plafa-PFI1800W , plafa-PFL2530W

Title : A Plasmodium phospholipase is involved in disruption of the liver stage parasitophorous vacuole membrane - Burda_2015_PLoS.Pathog_11_e1004760
Author(s) : Burda PC , Roelli MA , Schaffner M , Khan SM , Janse CJ , Heussler VT
Ref : PLoS Pathog , 11 :e1004760 , 2015
Abstract :
PubMedSearch : Burda_2015_PLoS.Pathog_11_e1004760
PubMedID: 25786000
Gene_locus related to this paper: plaba-q4z5z8 , plafa-MAL6P1.135 , plafa-PF10.0018

Title : Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13 - Hall_2002_Nature_419_527
Author(s) : Hall N , Pain A , Berriman M , Churcher C , Harris B , Harris D , Mungall K , Bowman S , Atkin R , Baker S , Barron A , Brooks K , Buckee CO , Burrows C , Cherevach I , Chillingworth C , Chillingworth T , Christodoulou Z , Clark L , Clark R , Corton C , Cronin A , Davies R , Davis P , Dear P , Dearden F , Doggett J , Feltwell T , Goble A , Goodhead I , Gwilliam R , Hamlin N , Hance Z , Harper D , Hauser H , Hornsby T , Holroyd S , Horrocks P , Humphray S , Jagels K , James KD , Johnson D , Kerhornou A , Knights A , Konfortov B , Kyes S , Larke N , Lawson D , Lennard N , Line A , Maddison M , McLean J , Mooney P , Moule S , Murphy L , Oliver K , Ormond D , Price C , Quail MA , Rabbinowitsch E , Rajandream MA , Rutter S , Rutherford KM , Sanders M , Simmonds M , Seeger K , Sharp S , Smith R , Squares R , Squares S , Stevens K , Taylor K , Tivey A , Unwin L , Whitehead S , Woodward J , Sulston JE , Craig A , Newbold C , Barrell BG
Ref : Nature , 419 :527 , 2002
Abstract :
PubMedSearch : Hall_2002_Nature_419_527
PubMedID: 12368867
Gene_locus related to this paper: plaf7-c0h4q4 , plafa-MAL6P1.135 , plafa-PFD0185C , plafa-PFI1775W , plafa-PFI1800W