5DYW-5hf-C11
General
Type : Piperidine, Derivative of Donepezil, Sulfur Compound, Sulfonamide, PET probe, Naphthalen
Chemical_Nomenclature : N-[(1-benzylpiperidin-3-yl)methyl]-N-(2-methoxyethyl)naphthalene-2-sulfonamide
Canonical SMILES : COCCN(CC1CCCN(C1)CC2=CC=CC=C2)S(=O)(=O)C3=CC4=CC=CC=C4C=C3
InChI : InChI=1S\/C26H32N2O3S\/c1-31-17-16-28(32(29,30)26-14-13-24-11-5-6-12-25(24)18-26)21-23-10-7-15-27(20-23)19-22-8-3-2-4-9-22\/h2-6,8-9,11-14,18,23H,7,10,15-17,19-21H2,1H3
InChIKey : NIHBOOKOQZGYSF-UHFFFAOYSA-N
Other name(s) : [11C]BChE_OMe || (+\/-)[11C]N-((1-Benzylpiperidin-3-yl)methyl)-N-(2-methoxyethyl)naphthalene-2-sulfonamide || CHEMBL4105611 || SCHEMBL18105284 || BDBM50246979
MW : 452.6
Formula : C26H32N2O3S
CAS_number :
PubChem : 122581936
UniChem : NIHBOOKOQZGYSF-UHFFFAOYSA-N
Target
Families : 5DYW-5hf-C11 ligand of proteins in family
BCHE
Protein :
human-BCHE
References (1)
| Title : Longitudinal evaluation of a novel BChE PET tracer as an early in vivo biomarker in the brain of a mouse model for Alzheimer disease - Rejc_2021_Theranostics_11_6542 |
| Author(s) : Rejc L , Gomez-Vallejo V , Joya A , Moreno O , Egimendia A , Castellnou P , Rios-Anglada X , Cossio U , Baz Z , Passannante R , Tobalina-Larrea I , Ramos-Cabrer P , Giralt A , Sastre M , Capetillo-Zarate E , Kosak U , Knez D , Gobec S , Marder M , Martin A , Llop J |
| Ref : Theranostics , 11 :6542 , 2021 |
| Abstract : |
| PubMedSearch : Rejc_2021_Theranostics_11_6542 |
| PubMedID: 33995675 |