Dibutyl-phthalate
Dibutyl phthalate is a plasticizer used in most plastics and found in water, air, soil, plants and animals. It may have some adverse effects with long-term exposure.
General
Type : Aryl ester, Phthalate
Chemical_Nomenclature : dibutyl benzene-1,2-dicarboxylate
Canonical SMILES : CCCCOC(=O)C1=CC=CC=C1C(=O)OCCCC
InChI : InChI=1S\/C16H22O4\/c1-3-5-11-19-15(17)13-9-7-8-10-14(13)16(18)20-12-6-4-2\/h7-10H,3-6,11-12H2,1-2H3
InChIKey : DOIRQSBPFJWKBE-UHFFFAOYSA-N
Other name(s) : Dibutyl phthalate || Dibutylphthalate || Di-n-butyl phthalate || N-Butyl phthalate || Butyl phthalate || Celluflex DBP || DBP || C6H4(COOC4H9)2
MW : 278.34
Formula : C16H22O4
CAS_number : 84-74-2
PubChem : 3026
UniChem : DOIRQSBPFJWKBE-UHFFFAOYSA-N
Target
Structures : No structure
Families : HNLyase_Bact, Carb_B_Chordata, Hormone-sensitive_lipase_like, Carb_B_Bacteria, 6_AlphaBeta_hydrolase, LYsophospholipase_carboxylesterase, Fungal_carboxylesterase_lipase
References (19)
| Title : Wide substrate range for a candidate bioremediation enzyme isolated from Nocardioides sp. strain SG-4 G - Krishnani_2023_FEMS.Microbiol.Lett_370_ |
| Author(s) : Krishnani KK , Oakeshott JG , Pandey G |
| Ref : FEMS Microbiology Letters , 370 : , 2023 |
| Abstract : |
| PubMedSearch : Krishnani_2023_FEMS.Microbiol.Lett_370_ |
| PubMedID: 37660276 |
| Gene_locus related to this paper: 9acto-c8cp46 |
| Title : Hydrolysis of dibutyl phthalate and di(2-ethylhexyl) phthalate in human liver, small intestine, kidney, and lung: An in vitro analysis using organ subcellular fractions and recombinant carboxylesterases - Isobe_2023_Chem.Biol.Interact_372_110353 |
| Author(s) : Isobe T , Ohkawara S , Mori Y , Jinno H , Tanaka-Kagawa T , Hanioka N |
| Ref : Chemico-Biological Interactions , 372 :110353 , 2023 |
| Abstract : |
| PubMedSearch : Isobe_2023_Chem.Biol.Interact_372_110353 |
| PubMedID: 36657734 |
| Gene_locus related to this paper: human-CES1 , mouse-Ces1c |
| Title : Complete degradation of di-n-butyl phthalate by Glutamicibacter sp. strain 0426 with a novel pathway - Ren_2023_Biodegradation__ |
| Author(s) : Ren C , Wang Y , Wu Y , Zhao HP , Li L |
| Ref : Biodegradation , : , 2023 |
| Abstract : |
| PubMedSearch : Ren_2023_Biodegradation__ |
| PubMedID: 37395851 |
| Gene_locus related to this paper: 9micc-a0a5c2fpe7 |
| Title : Substrate-enzyme interactions and catalytic mechanism in a novel family VI esterase with dibutyl phthalate-hydrolyzing activity - Cheng_2023_Environ.Int_178_108054 |
| Author(s) : Cheng J , Du H , Zhou MS , Ji Y , Xie YQ , Huang HB , Zhang SH , Li F , Xiang L , Cai QY , Li YW , Li H , Li M , Zhao HM , Mo CH |
| Ref : Environ Int , 178 :108054 , 2023 |
| Abstract : |
| PubMedSearch : Cheng_2023_Environ.Int_178_108054 |
| PubMedID: 37354883 |
| Gene_locus related to this paper: pseae-PA3859 |
| Title : An efficient phthalate ester-degrading Bacillus subtilis: Degradation kinetics, metabolic pathway, and catalytic mechanism of the key enzyme - Xu_2021_Environ.Pollut_273_116461 |
| Author(s) : Xu Y , Liu X , Zhao J , Huang H , Wu M , Li X , Li W , Sun X , Sun B |
| Ref : Environ Pollut , 273 :116461 , 2021 |
| Abstract : |
| PubMedSearch : Xu_2021_Environ.Pollut_273_116461 |
| PubMedID: 33485001 |
| Gene_locus related to this paper: bacsu-pnbae |
| Title : First identification and characterization of detoxifying plastic-degrading DBP hydrolases in the marine diatom Cylindrotheca closterium - Vingiani_2021_Sci.Total.Environ_812_152535 |
| Author(s) : Vingiani GM , Leone S , De Luca D , Borra M , Dobson ADW , Ianora A , De Luca P , Lauritano C |
| Ref : Sci Total Environ , 812 :152535 , 2021 |
| Abstract : |
| PubMedSearch : Vingiani_2021_Sci.Total.Environ_812_152535 |
| PubMedID: 34942245 |
| Gene_locus related to this paper: 9stra-DBPH1 , 9stra-DBPH2 |
| Title : Development of a whole-cell biocatalyst for diisobutyl phthalate degradation by functional display of a carboxylesterase on the surface of Escherichia coli - Ding_2020_Microb.Cell.Fact_19_114 |
| Author(s) : Ding J , Zhou Y , Wang C , Peng Z , Mu Y , Tang X , Huang Z |
| Ref : Microb Cell Fact , 19 :114 , 2020 |
| Abstract : |
| PubMedSearch : Ding_2020_Microb.Cell.Fact_19_114 |
| PubMedID: 32471417 |
| Gene_locus related to this paper: bacsu-pnbae |
| Title : Characterization of XtjR8: A novel esterase with phthalate-hydrolyzing activity from a metagenomic library of lotus pond sludge - Qiu_2020_Int.J.Biol.Macromol_164_1510 |
| Author(s) : Qiu J , Yang H , Yan Z , Shi Y , Zou D , Ding L , Shao Y , Li L , Khan U , Sun S , Xin Z |
| Ref : Int J Biol Macromol , 164 :1510 , 2020 |
| Abstract : |
| PubMedSearch : Qiu_2020_Int.J.Biol.Macromol_164_1510 |
| PubMedID: 32755708 |
| Gene_locus related to this paper: 9zzzz-XtjR8 |
| Title : Gestational and lactational exposition to di-n-butyl phthalate increases neurobehavioral perturbations in rats: A three generational comparative study - Mahaboob Basha_2020_Toxicol.Rep_7_480 |
| Author(s) : Mahaboob Basha P , Radha MJ |
| Ref : Toxicol Rep , 7 :480 , 2020 |
| Abstract : |
| PubMedSearch : Mahaboob Basha_2020_Toxicol.Rep_7_480 |
| PubMedID: 32292708 |
| Title : Identification and characterization of a novel phthalate-degrading hydrolase from a soil metagenomic library - Qiu_2020_Ecotoxicol.Environ.Saf_190_110148 |
| Author(s) : Qiu J , Zhang Y , Shi Y , Jiang J , Wu S , Li L , Shao Y , Xin Z |
| Ref : Ecotoxicology & Environmental Safety , 190 :110148 , 2020 |
| Abstract : |
| PubMedSearch : Qiu_2020_Ecotoxicol.Environ.Saf_190_110148 |
| PubMedID: 31911388 |
| Gene_locus related to this paper: 9zzzz-EstJ6 |
| Title : Degradation of dibutyl phthalate (DBP) by a bacterial consortium and characterization of two novel esterases capable of hydrolyzing PAEs sequentially - Lu_2020_Ecotoxicol.Environ.Saf_195_110517 |
| Author(s) : Lu M , Jiang W , Gao Q , Zhang M , Hong Q |
| Ref : Ecotoxicology & Environmental Safety , 195 :110517 , 2020 |
| Abstract : |
| PubMedSearch : Lu_2020_Ecotoxicol.Environ.Saf_195_110517 |
| PubMedID: 32220793 |
| Gene_locus related to this paper: 9mico-DpeH , 9mico-MpeH |
| Title : Mechanistic insight into esterase-catalyzed hydrolysis of phthalate esters (PAEs) based on integrated multi-spectroscopic analyses and docking simulation - Du_2020_J.Hazard.Mater_408_124901 |
| Author(s) : Du H , Hu RW , Zhao HM , Huang HB , Xiang L , Liu BL , Feng NX , Li H , Li YW , Cai QY , Mo CH |
| Ref : J Hazard Mater , 408 :124901 , 2020 |
| Abstract : |
| PubMedSearch : Du_2020_J.Hazard.Mater_408_124901 |
| PubMedID: 33360702 |
| Gene_locus related to this paper: rhoso-a0a3g5hne7 |
| Title : Assessment of phthalate ester residues and distribution patterns in Baijiu raw materials and Baijiu - Dong_2019_Food.Chem_283_508 |
| Author(s) : Dong W , Guo R , Sun X , Li H , Zhao M , Zheng F , Sun J , Huang M , Wu J |
| Ref : Food Chem , 283 :508 , 2019 |
| Abstract : |
| PubMedSearch : Dong_2019_Food.Chem_283_508 |
| PubMedID: 30722905 |
| Title : Biochemical characterization of a novel lipase from Malbranchea cinnamomea suitable for production of lipolyzed milkfat flavor and biodegradation of phthalate esters - Duan_2019_Food.Chem_297_124925 |
| Author(s) : Duan X , Xiang M , Wang L , Yan Q , Yang S , Jiang Z |
| Ref : Food Chem , 297 :124925 , 2019 |
| Abstract : |
| PubMedSearch : Duan_2019_Food.Chem_297_124925 |
| PubMedID: 31253266 |
| Gene_locus related to this paper: malci-McLipB |
| Title : Biodegradation of di-n-butyl phthalate by psychrotolerant Sphingobium yanoikuyae strain P4 and protein structural analysis of carboxylesterase involved in the pathway - Mahajan_2019_Int.J.Biol.Macromol_122_806 |
| Author(s) : Mahajan R , Verma S , Kushwaha M , Singh D , Akhter Y , Chatterjee S |
| Ref : Int J Biol Macromol , 122 :806 , 2019 |
| Abstract : |
| PubMedSearch : Mahajan_2019_Int.J.Biol.Macromol_122_806 |
| PubMedID: 30395899 |
| Gene_locus related to this paper: sphya-k9da91 |
| Title : Carboxylesterase-involved metabolism of di-n-butyl phthalate in pumpkin (Cucurbita moschata) seedlings - Lin_2017_Environ.Pollut_220_421 |
| Author(s) : Lin Q , Chen S , Chao Y , Huang X , Wang S , Qiu R |
| Ref : Environ Pollut , 220 :421 , 2017 |
| Abstract : |
| PubMedSearch : Lin_2017_Environ.Pollut_220_421 |
| PubMedID: 27697378 |
| Title : Properties of a newly identified esterase from Bacillus sp. K91 and its novel function in diisobutyl phthalate degradation - Ding_2015_PLoS.One_10_e0119216 |
| Author(s) : Ding J , Wang C , Xie Z , Li J , Yang Y , Mu Y , Tang X , Xu B , Zhou J , Huang Z |
| Ref : PLoS ONE , 10 :e0119216 , 2015 |
| Abstract : |
| PubMedSearch : Ding_2015_PLoS.One_10_e0119216 |
| PubMedID: 25746227 |
| Gene_locus related to this paper: bacsu-pnbae |
| Title : Cloning of a dibutyl phthalate hydrolase gene from Acinetobacter sp. strain M673 and functional analysis of its expression product in Escherichia coli - Wu_2013_Appl.Microbiol.Biotechnol_97_2483 |
| Author(s) : Wu J , Liao X , Yu F , Wei Z , Yang L |
| Ref : Applied Microbiology & Biotechnology , 97 :2483 , 2013 |
| Abstract : |
| PubMedSearch : Wu_2013_Appl.Microbiol.Biotechnol_97_2483 |
| PubMedID: 22729233 |
| Gene_locus related to this paper: acilw-ESTA |
| Title : [Metabolism of dibutyl and diethyl phthalates in the rat] - |
| Author(s) : Chambon P , Riotte M , Daudon M , Chambon-Mougenot R , Bringuier J |
| Ref : C R Acad Hebd Seances Acad Sci D , 273 :2165 , 1971 |
| PubMedID: 5003086 |