Phthalate

Phthalates, or phthalate esters, are esters of phthalic acid. They are mainly used as plasticizers, i.e., substances added to plastics to increase their flexibility, transparency, durability, and longevity. Phthalate esters are endocrine disruptors.

Substrate	Main targeted enzyme familyes	Type
Dibutyl-phthalate	HNLyase_Bact Carb_B_Chordata Hormone-sensitive_lipase_like Carb_B_Bacteria 6_AlphaBeta_hydrolase LYsophospholipase_carboxylesterase Fungal_carboxylesterase_lipase	Aryl ester Phthalate
DaBTaBDa	Cutinase Polyesterase-lipase-cutinase	Terephthalate Phthalate
TdaBTaBTda	Cutinase Polyesterase-lipase-cutinase	Terephthalate Phthalate
HaBTaBHa	Cutinase Polyesterase-lipase-cutinase	Terephthalate Phthalate
Benzyl-butyl-phthalate	Fungal_carboxylesterase_lipase Cutinase	Phthalate Natural
N-(3-Carboxy-4-nitrophenyl)phthalamidic-acid	6_AlphaBeta_hydrolase	pNP Phthalate
1,4-butanediol-terephthalate		Terephthalate
BEB	Fungal_carboxylesterase_lipase	Polymer Polyester Terephthalate Aromatic polyester Benzoate
2HE(MHET)4	Polyesterase-lipase-cutinase	Polymer Polyester Terephthalate Aromatic polyester
2PET	Carb_B_Bacteria	Terephthalate Phthalate
2HE(MHET)2	Polyesterase-lipase-cutinase	Polymer Polyester Terephthalate Aromatic polyester
ETETETE	Polyesterase-lipase-cutinase	Polymer Polyester Terephthalate Aromatic polyester
TETET	Polyesterase-lipase-cutinase	Polymer Polyester Terephthalate Aromatic polyester
EMT	Polyesterase-lipase-cutinase	Polymer Polyester Terephthalate Aromatic polyester
EBT	Polyesterase-lipase-cutinase	Polymer Polyester Terephthalate Aromatic polyester
Cyclo-tris-ethylene-terephthalate	Cutinase Polyesterase-lipase-cutinase	Polymer Polyester Terephthalate Aromatic polyester
PBSTIL	Polyesterase-lipase-cutinase	Polymer Polyester Terephthalate co-polyester Aromatic polyester
Polytrimethylene-terephthalate		Polymer Polyester Terephthalate Aromatic polyester
Polybutylene-terephthalate		Polymer Polyester Terephthalate Aromatic polyester
DEHP	Carb_B_Chordata Cutinase Carb_B_Bacteria Carbon-carbon_bond_hydrolase Pancreatic_lipase	Phthalate
MEHP	Carbon-carbon_bond_hydrolase AlphaBeta_hydrolase	Phthalate
Terephthalic-acid		Terephthalate Phthalate
DMT	Tannase Carbon-carbon_bond_hydrolase	Terephthalate Phthalate
Diethyl-terephthalate	Carbon-carbon_bond_hydrolase Carb_B_Bacteria	Terephthalate Phthalate
Diallyl-terephthalate	Carbon-carbon_bond_hydrolase	Terephthalate Phthalate
BETE	Polyesterase-lipase-cutinase	Terephthalate Phthalate
BHBT	Polyesterase-lipase-cutinase Bacterial_lip_FamI.5	Terephthalate Phthalate
3-PBT	Polyesterase-lipase-cutinase Cutinase	Terephthalate Phthalate
BTa	Polyesterase-lipase-cutinase Cutinase	Terephthalate Phthalate
HEB	Carb_B_Bacteria	Terephthalate Phthalate
BECBA	Carb_B_Bacteria	Terephthalate Phthalate
BETEB	Polyesterase-lipase-cutinase Cutinase Carb_B_Bacteria Bacterial_lip_FamI.5	Terephthalate Phthalate
BHETA	Tannase	Terephthalate Phthalate Carboxamide
MpNPT	Tannase	Terephthalate Phthalate pNP Chromogen
HEMT	Polyesterase-lipase-cutinase	Terephthalate Phthalate
Mono(2-hydroxyethyl)-terephthalate	Polyesterase-lipase-cutinase Cutinase	Terephthalate Phthalate
MHET	Polyesterase-lipase-cutinase Tannase Carb_B_Bacteria FAE-Bacterial-promiscuous CarbLipBact_2	Terephthalate Phthalate Benzoate
BHET-OH	Polyesterase-lipase-cutinase	Terephthalate Phthalate
BHET	Polyesterase-lipase-cutinase Tannase Carb_B_Bacteria Cutinase Hormone-sensitive_lipase_like FAE-Bacterial-promiscuous CarbLipBact_1 CarbLipBact_2	Terephthalate Phthalate
Polyethylene-terephthalate	Polyesterase-lipase-cutinase 6_AlphaBeta_hydrolase Polyesterase-MGS0156-like Carb_B_Bacteria Duf_1400 Xaa-Pro-like_dom AlphaBeta_hydrolase FAE-Bacterial-promiscuous Chlorophyllase	Polymer Terephthalate Phthalate Polyester Aromatic polyester Benzoate
PBST		Polymer Polyester Terephthalate co-polyester
PBAT	Bacterial_lip_FamI.5 Carb_B_Bacteria Lipase_2 Polyesterase-lipase-cutinase Polyesterase-MGS0156-like 6_AlphaBeta_hydrolase BD-FAE Hormone-sensitive_lipase_like Cutinase	Polymer Polyester Terephthalate co-polyester Butyrate
Monobutyl-phthalate	Bacterial_esterase Hormone-sensitive_lipase_like Carbon-carbon_bond_hydrolase	Aryl ester Phthalate
Dioctyl-phthalate	HNLyase_Bact	Aryl ester Phthalate
Dipentyl-phthalate	Cholesterol_esterase	Aryl ester Phthalate
Dimethyl-phthalate	Hormone-sensitive_lipase_like HNLyase_Bact	Aryl ester Phthalate
Dipropyl-phthalate	Cutinase Fungal_carboxylesterase_lipase Cholesterol_esterase	Aryl ester Phthalate
Diisobutyl-phthalate	HNLyase_Bact Bacterial_esterase	Aryl ester Phthalate
Monoethyl-phthalate		Phthalate
Diethyl-phthalate	Hormone-sensitive_lipase_like Carb_B_Bacteria	Aryl ester Phthalate