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Leaving group

General

These are not truly inhibitors, but products of the acylation of the active site serine inhibited by the inhibitors. They can be found trapped in the structure of the inhibited enzyme
Inhibitor Main targeted enzyme families Type Structure
CHEMBL2152538 Not AlphaBeta Hydrolase target Isoquinoline Quinazoline Leaving group
4-piperidino-piperidine Carb_B_Chordata Leaving group Derivative of Irinotecan Piperidine
Bis-Noreseroline ACHE Leaving group Indole Derivative of physostigmine-eserine
Tetrahydrofurobenzofuran Leaving group Benzofuran
7-hydroxy-4-methylcoumarin Coumarin Chromen Leaving group
Geneseroline Natural Indole Derivative of physostigmine-eserine Leaving group