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Derivative of physostigmine-eserine

General

Physostigmine-eserine carbamate alkaloid purified from the calabar bean: Physostigma venenosum. Physostigmine is a cholinesterase inhibitor that is rapidly absorbed through membranes. It can be applied topically to the conjunctiva. It also can cross the blood-brain barrier.
Inhibitor Main targeted enzyme families Type Structure
Cyclohexylmethylcarbamate-phenethylnorphysostigmine-3u BCHE Derivative of physostigmine-eserine Carbamate
Debromoflustramine-B BCHE Natural Pyrrolidine Indole Derivative of physostigmine-eserine
Bis-Noreseroline ACHE Leaving group Indole Derivative of physostigmine-eserine
Cymserine BCHE Derivative of physostigmine-eserine Carbamate Indole
Dihydrobenzodioxepine-cymeserine BCHE Derivative of physostigmine-eserine Carbamate
Tetrahydrofurobenzofuran-cymserine ACHE Derivative of physostigmine-eserine Carbamate Benzofuran
(-)-phenethylcymserine Carb_B_Chordata BCHE ACHE Derivative of physostigmine-eserine Carbamate
Cymyl-carbamate-physovenol ACHE Derivative of physostigmine-eserine Carbamate
N1-Phenethylnorcymserine BCHE Derivative of physostigmine-eserine Carbamate Indole
Bisnorcymserine BCHE ACHE Carbamate Indole Derivative of physostigmine-eserine
Physovenine ACHE Carbamate Natural Indole Derivative of physostigmine-eserine
Ganstigmine ACHE Derivative of physostigmine-eserine Carbamate Indole
Eseroline ACHE Derivative of physostigmine-eserine Indole
Geneserine ACHE BCHE Natural Indole Carbamate Derivative of physostigmine-eserine Oxazine
Geneseroline Natural Indole Derivative of physostigmine-eserine Leaving group Oxazine
Heptylphysostigmine ACHE Derivative of physostigmine-eserine Carbamate Indole
MF217 ACHE Derivative of physostigmine-eserine Carbamate Morpholine Indole
MF268 ACHE Derivative of physostigmine-eserine Carbamate Morpholine Indole
Posiphen ACHE Derivative of physostigmine-eserine Carbamate Drug Indole
Phenserine ACHE Derivative of physostigmine-eserine Carbamate Drug Indole
Physostigmine-methiodide ACHE Derivative of physostigmine-eserine Natural_modified Carbamate Indole
Physostigmine~Eserine ACHE BCHE Arylacetamide_deacetylase Derivative of physostigmine-eserine Natural Carbamate Drug Indole
Quilostigmine ACHE Derivative of physostigmine-eserine Carbamate Isoquinoline Indole
Tolserine ACHE BCHE Derivative of physostigmine-eserine Carbamate Indole NTE inhibitor Not AlphaBeta Hydrolase target