Derivative of physostigmine-eserine

General

Physostigmine-eserine carbamate alkaloid purified from the calabar bean: Physostigma venenosum. Physostigmine is a cholinesterase inhibitor that is rapidly absorbed through membranes. It can be applied topically to the conjunctiva. It also can cross the blood-brain barrier.

Inhibitor	Main targeted enzyme families	Type
Cyclohexylmethylcarbamate-phenethylnorphysostigmine-3u	BCHE	Derivative of physostigmine-eserine Stigmine Carbamate
Debromoflustramine-B	BCHE	Natural Pyrrolidine Indole Derivative of physostigmine-eserine Stigmine
Bis-Noreseroline	ACHE BCHE	Leaving group Indole Derivative of physostigmine-eserine Stigmine
Cymserine	BCHE	Derivative of physostigmine-eserine Stigmine Carbamate Indole
Dihydrobenzodioxepine-cymeserine	BCHE	Derivative of physostigmine-eserine Stigmine Carbamate
Tetrahydrofurobenzofuran-cymserine	ACHE	Derivative of physostigmine-eserine Stigmine Carbamate Benzofuran
(-)-phenethylcymserine	Carb_B_Chordata BCHE ACHE	Derivative of physostigmine-eserine Stigmine Carbamate
Cymyl-carbamate-physovenol	ACHE	Derivative of physostigmine-eserine Stigmine Carbamate
N1-Phenethylnorcymserine	BCHE	Derivative of physostigmine-eserine Stigmine Carbamate Indole
Bisnorcymserine	BCHE ACHE	Carbamate Indole Derivative of physostigmine-eserine Stigmine
Physovenine	ACHE	Carbamate Natural Indole Derivative of physostigmine-eserine Stigmine
Ganstigmine	ACHE	Derivative of physostigmine-eserine Stigmine Carbamate Indole Organochlorine
Eseroline	ACHE	Derivative of physostigmine-eserine Stigmine Indole
Geneserine	ACHE BCHE	Natural Indole Carbamate Derivative of physostigmine-eserine Stigmine Oxazine
Geneseroline		Natural Indole Derivative of physostigmine-eserine Stigmine Leaving group Oxazine
Heptylphysostigmine	ACHE	Derivative of physostigmine-eserine Stigmine Carbamate Indole
MF231	ACHE	Derivative of physostigmine-eserine Stigmine Carbamate Morpholine Indole
MF217	ACHE	Derivative of physostigmine-eserine Stigmine Carbamate Morpholine Indole
MF268	ACHE	Derivative of physostigmine-eserine Stigmine Carbamate Morpholine Indole
Posiphen	ACHE	Derivative of physostigmine-eserine Stigmine Carbamate Drug Indole
Phenserine	ACHE	Derivative of physostigmine-eserine Stigmine Carbamate Drug Indole
Physostigmine-methiodide	ACHE	Derivative of physostigmine-eserine Stigmine Natural_modified Carbamate Indole
Physostigmine~Eserine	ACHE BCHE Arylacetamide_deacetylase	Derivative of physostigmine-eserine Stigmine Natural Carbamate Drug Indole
Quilostigmine	ACHE	Derivative of physostigmine-eserine Stigmine Carbamate Isoquinoline Indole
Tolserine	ACHE BCHE	Derivative of physostigmine-eserine Stigmine Carbamate Indole NTE inhibitor Not AlphaBeta Hydrolase target OPIDN-OP