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Quinazoline

General

Building block for many inhibitors of enzymes
Inhibitor Main targeted enzyme families Type Structure
3-(Dimethylamino)-N-propanamide-Tryptanthrin ACHE Derivative of Deoxyvasicinone Quinazoline Indole
CHEMBL4207101 BCHE ACHE Derivative of Deoxyvasicinone Quinazoline Metal ion chelator
Dihydroquinazoline-carboxamide-34 Epoxide_hydrolase Carboxamide Multitarget 5-Lipoxygenase inhibitor Sulfur Compound Quinazoline
3-(Quinazolin-4-ylthio)propanoic-acid Pectinacetylesterase-Notum Fragment inhibitor of Notum Sulfur Compound Quinazoline
CHEMBL2152538 Not A\/B H target Isoquinoline Quinazoline Leaving group
Tetracyclic-carbamate-cp8 BCHE PET probe Carbamate Natural_modified Derivative of Evodiamine Isoquinoline Quinazoline
Tetracyclic-carbamate-melatonine-3c BCHE Carbamate Natural_modified Derivative of Evodiamine Isoquinoline Quinazoline Derivative of Tryptamine Indole Alkyl linked bis-ligand
Tetracyclic-carbamate-ferulicacid-4a BCHE Carbamate Natural_modified Derivative of Evodiamine Isoquinoline Quinazoline Feruloyl Antioxidant Alkyl linked bis-ligand
Tetracyclic-carbamate-UW-MD-95 BCHE Carbamate Natural_modified Derivative of Evodiamine Isoquinoline Quinazoline
CHEMBL4454960 BCHE Morpholine Isoquinoline Carbamate Quinazoline
75M-5T4F DPP4N_Peptidase_S9 Piperidine Quinazoline Cyanide Purine
75L-5T4E DPP4N_Peptidase_S9 Piperidine Pyrimidine Quinazoline Purine
75N-5T4B DPP4N_Peptidase_S9 Piperidine Quinazoline Purine
UW-MD-71 ACHE BCHE Cholinesterase Piperidine Quinazoline Multitarget Histamine-Receptor3-H3-Antagonist
QADD2 RsbQ-like Quinazoline
Tetracyclic-carbamate-photoswitch-azo BCHE Carbamate Natural_modified Derivative of Evodiamine Isoquinoline Quinazoline Photoswitch
5ALR-8TM Epoxide_hydrolase Sulfur Compound Trifluoro Quinazoline
Linagliptin DPP4N_Peptidase_S9 Drug Purine Gliptin Quinazoline
Quinazolin-carbamate-2p BCHE Quinazoline Carbamate Sulfur Compound Thiophen
CI-1002 ACHE Derivative of Tacrine Muscarinic antagonist Quinazoline Azepane
Desoxypeganine ACHE BCHE Not A\/B H target Alkaloid Natural Quinazoline