ESTHER database
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Type Inhibitor
Nicotinic agonist
Nicotinic agonist
General
Not an alpha/beta hydrolase target but can be used as a building block for larger inhibitors of enzymes of the family designed as multitarget compounds
Inhibitor
Main targeted enzyme families
Type
Structure
Cotinine
Pectinacetylesterase-Notum
Derivative of Nicotine
Pyrrolidine
Natural
Alkaloid
Drug
Nicotinic agonist
Not A\/B H target
BisQ
ACHE
Analogue of substrate
Trimethylammonium
Bisquaternary
Not A\/B H target
Nicotinic agonist
Photoswitch
p-phenylazophenyltrimethylammonium
Photoswitch
Trimethylammonium
Not A\/B H target
Nicotinic agonist
N-p-phenylazophenylcarbamylcholine
Photoswitch
Trimethylammonium
Not A\/B H target
Nicotinic agonist
Galanthamine
ACHE
Derivative of Galanthamine
Natural
Alkaloid
Drug
Benzazepin
Azepane
Multitarget
Nicotinic agonist
Nicotine
ACHE
BCHE
Pectinacetylesterase-Notum
Derivative of Nicotine
Pyrrolidine
Natural
Alkaloid
Drug
Nicotinic agonist
Not A\/B H target