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| Title : Exploring the Potential of Sulfonamide-Dihydropyridine Hybrids as Multitargeted Ligands for Alzheimer's Disease Treatment - Dakhlaoui_2023_Int.J.Mol.Sci_24_ |
| Author(s) : Dakhlaoui I , Bernard PJ , Pietrzak D , Simakov A , Maj M , Refouvelet B , Beduneau A , Cornu R , Jozwiak K , Chabchoub F , Iriepa I , Martin H , Marco-Contelles J , Ismaili L |
| Ref : Int J Mol Sci , 24 : , 2023 |
| Abstract : Dakhlaoui_2023_Int.J.Mol.Sci_24_ |
| ESTHER : Dakhlaoui_2023_Int.J.Mol.Sci_24_ |
| PubMedSearch : Dakhlaoui_2023_Int.J.Mol.Sci_24_ |
| PubMedID: 37298693 |
| Title : Discovery of novel multifunctional ligands targeting GABA transporters, butyrylcholinesterase, beta-secretase, and amyloid beta aggregation as potential treatment of Alzheimer's disease - Zareba_2023_Eur.J.Med.Chem_261_115832 |
| Author(s) : Zareba P , Latka K , Mazur G , Gryzlo B , Pasieka A , Godyn J , Panek D , Skrzypczak-Wiercioch A , Hofner GC , Latacz G , Maj M , Espargaro A , Sabate R , Jozwiak K , Wanner KT , Salat K , Malawska B , Kulig K , Bajda M |
| Ref : Eur Journal of Medicinal Chemistry , 261 :115832 , 2023 |
| Abstract : Zareba_2023_Eur.J.Med.Chem_261_115832 |
| ESTHER : Zareba_2023_Eur.J.Med.Chem_261_115832 |
| PubMedSearch : Zareba_2023_Eur.J.Med.Chem_261_115832 |
| PubMedID: 37837674 |
| Title : Biginelli Reaction Synthesis of Novel Multitarget-Directed Ligands with Ca(2+) Channel Blocking Ability, Cholinesterase Inhibition, Antioxidant Capacity, and Nrf2 Activation - Malek_2022_Molecules_28_ |
| Author(s) : Malek R , Simakov A , Davis A , Maj M , Bernard PJ , Wnorowski A , Martin H , Marco-Contelles J , Chabchoub F , Dallemagne P , Rochais C , Jozwiak K , Ismaili L |
| Ref : Molecules , 28 : , 2022 |
| Abstract : Malek_2022_Molecules_28_ |
| ESTHER : Malek_2022_Molecules_28_ |
| PubMedSearch : Malek_2022_Molecules_28_ |
| PubMedID: 36615267 |
| Title : Effects of Linkers and Substitutions on Multitarget Directed Ligands for Alzheimer's Diseases: Emerging Paradigms and Strategies - Pravin_2022_Int.J.Mol.Sci_23_ |
| Author(s) : Pravin N , Jozwiak K |
| Ref : Int J Mol Sci , 23 : , 2022 |
| Abstract : Pravin_2022_Int.J.Mol.Sci_23_ |
| ESTHER : Pravin_2022_Int.J.Mol.Sci_23_ |
| PubMedSearch : Pravin_2022_Int.J.Mol.Sci_23_ |
| PubMedID: 35682763 |
| Title : Synthesis of new Hantzsch adducts showing Ca(2+) channel blockade capacity, cholinesterase inhibition and antioxidant power - Pachon-Angona_2021_Future.Med.Chem__ |
| Author(s) : Pachon-Angona I , Maj M , Wnorowski A , Martin H , Jozwiak K , Ismaili L |
| Ref : Future Med Chem , : , 2021 |
| Abstract : Pachon-Angona_2021_Future.Med.Chem__ |
| ESTHER : Pachon-Angona_2021_Future.Med.Chem__ |
| PubMedSearch : Pachon-Angona_2021_Future.Med.Chem__ |
| PubMedID: 34402661 |
| Title : Synthesis of Hantzsch Adducts as Cholinesterases and Calcium Flux inhibitors, Antioxidants and Neuroprotectives - Pachon_2020_Int.J.Mol.Sci_21_ |
| Author(s) : Pachon Angona I , Martin H , Daniel S , Moraleda I , Bonet A , Wnorowski A , Maj M , Jozwiak K , Iriepa I , Refouvelet B , Marco-Contelles J , Ismaili L |
| Ref : Int J Mol Sci , 21 : , 2020 |
| Abstract : Pachon_2020_Int.J.Mol.Sci_21_ |
| ESTHER : Pachon_2020_Int.J.Mol.Sci_21_ |
| PubMedSearch : Pachon_2020_Int.J.Mol.Sci_21_ |
| PubMedID: 33081112 |
| Title : Tacripyrimidines, the first tacrine-dihydropyrimidine hybrids, as multi-target-directed ligands for Alzheimer's disease - Chioua_2018_Eur.J.Med.Chem_155_839 |
| Author(s) : Chioua M , Buzzi E , Moraleda I , Iriepa I , Maj M , Wnorowski A , Giovannini C , Tramarin A , Portali F , Ismaili L , Lopez-Alvarado P , Bolognesi ML , Jozwiak K , Menendez JC , Marco-Contelles J , Bartolini M |
| Ref : Eur Journal of Medicinal Chemistry , 155 :839 , 2018 |
| Abstract : Chioua_2018_Eur.J.Med.Chem_155_839 |
| ESTHER : Chioua_2018_Eur.J.Med.Chem_155_839 |
| PubMedSearch : Chioua_2018_Eur.J.Med.Chem_155_839 |
| PubMedID: 29958119 |
| Title : Determination of affinity and efficacy of acetylcholinesterase inhibitors using isothermal titration calorimetry - Draczkowski_2016_Biochim.Biophys.Acta_1860_967 |
| Author(s) : Draczkowski P , Tomaszuk A , Halczuk P , Strzemski M , Matosiuk D , Jozwiak K |
| Ref : Biochimica & Biophysica Acta , 1860 :967 , 2016 |
| Abstract : Draczkowski_2016_Biochim.Biophys.Acta_1860_967 |
| ESTHER : Draczkowski_2016_Biochim.Biophys.Acta_1860_967 |
| PubMedSearch : Draczkowski_2016_Biochim.Biophys.Acta_1860_967 |
| PubMedID: 26586471 |
| Title : Positive allosteric modulators of alpha7 nicotinic acetylcholine receptors affect neither the function of other ligand- and voltage-gated ion channels and acetylcholinesterase, nor beta-amyloid content - Arias_2016_Int.J.Biochem.Cell.Biol_76_19 |
| Author(s) : Arias HR , Ravazzini F , Targowska-Duda KM , Kaczor AA , Feuerbach D , Boffi JC , Draczkowski P , Montag D , Brown BM , Elgoyhen AB , Jozwiak K , Puia G |
| Ref : International Journal of Biochemistryistry & Cell Biology , 76 :19 , 2016 |
| Abstract : Arias_2016_Int.J.Biochem.Cell.Biol_76_19 |
| ESTHER : Arias_2016_Int.J.Biochem.Cell.Biol_76_19 |
| PubMedSearch : Arias_2016_Int.J.Biochem.Cell.Biol_76_19 |
| PubMedID: 27129924 |
| Title : Antidepressant activity in mice elicited by 3-furan-2-yl-N-p-tolyl-acrylamide, a positive allosteric modulator of the alpha7 nicotinic acetylcholine receptor - Targowska-Duda_2014_Neurosci.Lett_569_126 |
| Author(s) : Targowska-Duda KM , Feuerbach D , Biala G , Jozwiak K , Arias HR |
| Ref : Neuroscience Letters , 569 :126 , 2014 |
| Abstract : Targowska-Duda_2014_Neurosci.Lett_569_126 |
| ESTHER : Targowska-Duda_2014_Neurosci.Lett_569_126 |
| PubMedSearch : Targowska-Duda_2014_Neurosci.Lett_569_126 |
| PubMedID: 24708923 |
| Title : Molecular interactions between mecamylamine enantiomers and the transmembrane domain of the human alpha4beta2 nicotinic receptor - Bondarenko_2014_Biochemistry_53_908 |
| Author(s) : Bondarenko V , Targowska-Duda KM , Jozwiak K , Tang P , Arias HR |
| Ref : Biochemistry , 53 :908 , 2014 |
| Abstract : Bondarenko_2014_Biochemistry_53_908 |
| ESTHER : Bondarenko_2014_Biochemistry_53_908 |
| PubMedSearch : Bondarenko_2014_Biochemistry_53_908 |
| PubMedID: 24437521 |
| Title : Bupropion-induced inhibition of alpha7 nicotinic acetylcholine receptors expressed in heterologous cells and neurons from dorsal raphe nucleus and hippocampus - Vazquez-Gomez_2014_Eur.J.Pharmacol_740C_103 |
| Author(s) : Vazquez-Gomez E , Arias HR , Feuerbach D , Miranda-Morales M , Mihailescu S , Targowska-Duda KM , Jozwiak K , Garcia-Colunga J |
| Ref : European Journal of Pharmacology , 740C :103 , 2014 |
| Abstract : Vazquez-Gomez_2014_Eur.J.Pharmacol_740C_103 |
| ESTHER : Vazquez-Gomez_2014_Eur.J.Pharmacol_740C_103 |
| PubMedSearch : Vazquez-Gomez_2014_Eur.J.Pharmacol_740C_103 |
| PubMedID: 25016090 |
| Title : Role of the nicotinic receptor beta4 subunit in the antidepressant activity of novel N,6-dimethyltricyclo[5.2.1.0(2),(6)]decan-2-amine enantiomers - Targowska-Duda_2013_Neurosci.Lett_553_186 |
| Author(s) : Targowska-Duda KM , Jozwiak K , Arias HR |
| Ref : Neuroscience Letters , 553 :186 , 2013 |
| Abstract : Targowska-Duda_2013_Neurosci.Lett_553_186 |
| ESTHER : Targowska-Duda_2013_Neurosci.Lett_553_186 |
| PubMedSearch : Targowska-Duda_2013_Neurosci.Lett_553_186 |
| PubMedID: 23994392 |
| Title : Structural and functional interaction of (+\/-)-2-(N-tert-butylamino)-3'-iodo-4'-azidopropiophenone, a photoreactive bupropion derivative, with nicotinic acetylcholine receptors - Arias_2012_Neurochem.Int_61_1433 |
| Author(s) : Arias HR , Feuerbach D , Targowska-Duda KM , Aggarwal S , Lapinsky DJ , Jozwiak K |
| Ref : Neurochem Int , 61 :1433 , 2012 |
| Abstract : Arias_2012_Neurochem.Int_61_1433 |
| ESTHER : Arias_2012_Neurochem.Int_61_1433 |
| PubMedSearch : Arias_2012_Neurochem.Int_61_1433 |
| PubMedID: 23103524 |
| Title : Structure-activity relationship of ibogaine analogs interacting with nicotinic acetylcholine receptors in different conformational states - Arias_2011_Int.J.Biochem.Cell.Biol_43_1330 |
| Author(s) : Arias HR , Feuerbach D , Targowska-Duda KM , Jozwiak K |
| Ref : International Journal of Biochemistry & Cell Biology , 43 :1330 , 2011 |
| Abstract : Arias_2011_Int.J.Biochem.Cell.Biol_43_1330 |
| ESTHER : Arias_2011_Int.J.Biochem.Cell.Biol_43_1330 |
| PubMedSearch : Arias_2011_Int.J.Biochem.Cell.Biol_43_1330 |
| PubMedID: 21642011 |
| Title : Catharanthine alkaloids are noncompetitive antagonists of muscle-type nicotinic acetylcholine receptors - Arias_2010_Neurochem.Int_57_153 |
| Author(s) : Arias HR , Feuerbach D , Targowska-Duda KM , Jozwiak K |
| Ref : Neurochem Int , 57 :153 , 2010 |
| Abstract : Arias_2010_Neurochem.Int_57_153 |
| ESTHER : Arias_2010_Neurochem.Int_57_153 |
| PubMedSearch : Arias_2010_Neurochem.Int_57_153 |
| PubMedID: 20493225 |
| Title : Interaction of selective serotonin reuptake inhibitors with neuronal nicotinic acetylcholine receptors - Arias_2010_Biochemistry_49_5734 |
| Author(s) : Arias HR , Feuerbach D , Targowska-Duda KM , Russell M , Jozwiak K |
| Ref : Biochemistry , 49 :5734 , 2010 |
| Abstract : Arias_2010_Biochemistry_49_5734 |
| ESTHER : Arias_2010_Biochemistry_49_5734 |
| PubMedSearch : Arias_2010_Biochemistry_49_5734 |
| PubMedID: 20527991 |
| Title : Interaction of 18-methoxycoronaridine with nicotinic acetylcholine receptors in different conformational states - Arias_2010_Biochim.Biophys.Acta_1798_1153 |
| Author(s) : Arias HR , Rosenberg A , Feuerbach D , Targowska-Duda KM , Maciejewski R , Jozwiak K , Moaddel R , Glick SD , Wainer IW |
| Ref : Biochimica & Biophysica Acta , 1798 :1153 , 2010 |
| Abstract : Arias_2010_Biochim.Biophys.Acta_1798_1153 |
| ESTHER : Arias_2010_Biochim.Biophys.Acta_1798_1153 |
| PubMedSearch : Arias_2010_Biochim.Biophys.Acta_1798_1153 |
| PubMedID: 20303928 |
| Title : Tricyclic antidepressants and mecamylamine bind to different sites in the human alpha4beta2 nicotinic receptor ion channel - Arias_2010_Int.J.Biochem.Cell.Biol_42_1007 |
| Author(s) : Arias HR , Rosenberg A , Targowska-Duda KM , Feuerbach D , Jozwiak K , Moaddel R , Wainer IW |
| Ref : International Journal of Biochemistry & Cell Biology , 42 :1007 , 2010 |
| Abstract : Arias_2010_Int.J.Biochem.Cell.Biol_42_1007 |
| ESTHER : Arias_2010_Int.J.Biochem.Cell.Biol_42_1007 |
| PubMedSearch : Arias_2010_Int.J.Biochem.Cell.Biol_42_1007 |
| PubMedID: 20223294 |
| Title : Interaction of ibogaine with human alpha3beta4-nicotinic acetylcholine receptors in different conformational states - Arias_2010_Int.J.Biochem.Cell.Biol_42_1525 |
| Author(s) : Arias HR , Rosenberg A , Targowska-Duda KM , Feuerbach D , Yuan XJ , Jozwiak K , Moaddel R , Wainer IW |
| Ref : International Journal of Biochemistry & Cell Biology , 42 :1525 , 2010 |
| Abstract : Arias_2010_Int.J.Biochem.Cell.Biol_42_1525 |
| ESTHER : Arias_2010_Int.J.Biochem.Cell.Biol_42_1525 |
| PubMedSearch : Arias_2010_Int.J.Biochem.Cell.Biol_42_1525 |
| PubMedID: 20684041 |
| Title : Different interaction between tricyclic antidepressants and mecamylamine with the human alpha3beta4 nicotinic acetylcholine receptor ion channel - Arias_2010_Neurochem.Int_56_642 |
| Author(s) : Arias HR , Targowska-Duda KM , Feuerbach D , Sullivan CJ , Maciejewski R , Jozwiak K |
| Ref : Neurochem Int , 56 :642 , 2010 |
| Abstract : Arias_2010_Neurochem.Int_56_642 |
| ESTHER : Arias_2010_Neurochem.Int_56_642 |
| PubMedSearch : Arias_2010_Neurochem.Int_56_642 |
| PubMedID: 20117161 |
| Title : Interaction of bupropion with muscle-type nicotinic acetylcholine receptors in different conformational states - Arias_2009_Biochemistry_48_4506 |
| Author(s) : Arias HR , Gumilar F , Rosenberg A , Targowska-Duda KM , Feuerbach D , Jozwiak K , Moaddel R , Wainer IW , Bouzat C |
| Ref : Biochemistry , 48 :4506 , 2009 |
| Abstract : Arias_2009_Biochemistry_48_4506 |
| ESTHER : Arias_2009_Biochemistry_48_4506 |
| PubMedSearch : Arias_2009_Biochemistry_48_4506 |
| PubMedID: 19334677 |
| Title : Identifying the binding site(s) for antidepressants on the Torpedo nicotinic acetylcholine receptor: [3H]2-azidoimipramine photolabeling and molecular dynamics studies - Sanghvi_2008_Biochim.Biophys.Acta_1778_2690 |
| Author(s) : Sanghvi M , Hamouda AK , Jozwiak K , Blanton MP , Trudell JR , Arias HR |
| Ref : Biochimica & Biophysica Acta , 1778 :2690 , 2008 |
| Abstract : Sanghvi_2008_Biochim.Biophys.Acta_1778_2690 |
| ESTHER : Sanghvi_2008_Biochim.Biophys.Acta_1778_2690 |
| PubMedSearch : Sanghvi_2008_Biochim.Biophys.Acta_1778_2690 |
| PubMedID: 18817747 |
| Title : Enantioselective interactions of dextromethorphan and levomethorphan with the alpha 3 beta 4-nicotinic acetylcholine receptor: comparison of chromatographic and functional data - Jozwiak_2003_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_797_373 |
| Author(s) : Jozwiak K , Hernandez SC , Kellar KJ , Wainer IW |
| Ref : Journal of Chromatography B Analyt Technol Biomed Life Sciences , 797 :373 , 2003 |
| Abstract : Jozwiak_2003_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_797_373 |
| ESTHER : Jozwiak_2003_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_797_373 |
| PubMedSearch : Jozwiak_2003_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_797_373 |
| PubMedID: 14630163 |