Family: Haloalkane_dehalogenase-HLD1

Block: X

Parent Family: Epoxide-hydrolase_like


Haloalkane dehalogenases (HLDs) are enzymes that catalyze the cleavage of carbon halogen bonds by a hydrolytic mechanism. The catalytic triad consists of the key nucleophile (Asp) the general base (His) and a catalytic acid (Asp or Glu). HLD where subdivided in three subfamily (Chovancova et al.) according to their substrate specificity and position of active site residues. Class one HLD1 (HLD-I) has catalytic triad Asp-His-Asp and halide-strabilizing residues Trp-Trp. Class two HLDII (HLD-II) has catalytic triad Asp-His-Glu and halide-stabilizing residues Asn-Trp. Class three HLDIII (HLD-III) has catalytic triad Asp-His-Asp and halide-strabilizing residues Asn-Trp. Also the reaction performed is different, the Renilla reniformis luciferase belongs to this family. In ESTHER as in HAMAP database class I and III are merged as they are close. OleB from bacterial hydrocarbon biosynthesis is a -lactone decarboxylase (Christenson et al.2017)


Interpro : IPR023489 Haloalkane dehalogenase, subfamily 1


Pdoc : No Pdoc

Pfam : PF00561 Abhydrolase_1

Prints : No Print

EC Number :


Peptide in Fasta
Nucleotide in Fasta
Alignment with Multalin Text only
Seed alignment with MAFFT No colour / coloured with Mview
Alignment with MAFFT No colour / coloured with Mview
Dendrogram The dnd file

Structure Name Proteins
1EDB Xanthobacter autotrophicus haloalkane dehalogenase at PH 6.2 xanau-halo1
1EDD Xanthobacter autotrophicus haloalkane dehalogenase at PH 8 xanau-halo1
1EDE Xanthobacter autotrophicus haloalkane dehalogenase at PH 8.2 xanau-halo1
2DHC Xanthobacter autotrophicus haloalkane dehalogenase + 1,2-dichloroethane at 4 Deg celcius xanau-halo1
2DHD Xanthobacter autotrophicus haloalkane dehalogenase + 1,2-dichloroethane at room temp xanau-halo1
2DHE Xanthobacter autotrophicus haloalkane dehalogenase at room temp PH 6 xanau-halo1
2EDA Xanthobacter autotrophicus haloalkane dehalogenase + iodine xanau-halo1
2EDC Xanthobacter autotrophicus haloalkane dehalogenase xanau-halo1
2HAD Xanthobacter autotrophicus haloalkane dehalogenase xanau-halo1
1HDE Xanthobacter autotrophicus haloalkane dehalogenase F172W mutant xanau-halo1
1BE0 Xanthobacter autotrophicus haloalkane dehalogenase (pH 5.0) +acetic acid xanau-halo1
1BEE Xanthobacter autotrophicus haloalkane dehalogenase W175Y mutant xanau-halo1
1BEZ Xanthobacter autotrophicus haloalkane dehalogenase W175Y mutant (pH 5.0) xanau-halo1
1B6G Haloalkane dehalogenase at Ph 5.0 containing chloride xanau-halo1
1CIJ Haloalkane dehalogenase soaked with high concentration of bromide xanau-halo1
8CKP X-ray structure of the crystallization-prone form of subfamily III haloalkane dehalogenase DhmeA from Haloferax mediterranei DhmeA-III halmt-DhmeAIII
8OOH Cryo-EM map of the focused refinement of the subfamily III haloalkane dehalogenase from Haloferax mediterranei dimer forming hexameric assembly halmt-DhmeAIII
7AVR The tetrameric structure of haloalkane dehalogenase DpaA from Paraglaciecola agarilytica NO2 9alte-k6xnl5
6F9O Crystal structure of cold-adapted haloalkane dehalogenase DpcA from Psychrobacter cryohalolentis K5 psyck-q1qbb9
5MXP Haloalkane dehalogenase DmxA from Marinobacter sp. ELB17 possessing a unique catalytic residue 9alte-a3jb27
5ESR Crystal structure of haloalkane dehalogenase (DccA) from Caulobacter crescentus caucr-CC1175
4MJ3 Haloalkane dehalogenases from Mycobacterium rhodesiae JS60 mycrh-g4i2j6
2XT0 Dehalogenase DPpA from Plesiocystis pacifica SIR-I 9delt-a6g7b1
2PKY The Effect of Deuteration on Protein Structure A High Resolution Comparison of Hydrogenous and Perdeuterated Haloalkane Dehalogenase xanau-halo1
2YXP The Effect of Deuteration on Protein Structure A High Resolution Comparison of Hydrogenous and Perdeuterated Haloalkane Dehalogenase xanau-halo1

Gene_locus Name Species
halmt-DhmeAIII Haloferax mediterranei subfamily III haloalkane dehalogenase DhmeA DhmeA-III Haloferax mediterranei
shehh-b0tml1 Shewanella halifaxensis (strain HAW-EB4) Haloalkane dehalogenase HLDIII DshA Shewanella halifaxensis HAW-EB4
9gamm-a6faz5 Moritella sp. PE36 haloalkane dehalogenase HLDIII DmoxA Moritella sp. PE36
9caul-a0a1e4h0f2 Phenylobacterium sp. SCN 70-31 Haloalkane dehalogenase HLD1 DphexA Phenylobacterium sp. SCN 70-31
9prot-a0a0f2rdt1 Hyphomonas sp. BRH_c22 Haloalkane dehalogenase HLD1 DhxA Hyphomonas sp. BRH_c22
9sphn-a0a2d6h3s9 Blastomonas sp. Haloalkane dehalogenase HLD1 DprxA Blastomonas sp.
9delt-a0a0m4d813 Desulfuromonas soudanensis Haloalkane dehalogenase HLDIII DdsA Desulfuromonas soudanensis
9actn-a0a1g6re71 Nocardioides lianchengensis Haloalkane dehalogenase HLD1 DnlA Nocardioides lianchengensis
9actn-g7h6v4 Gordonia araii NBRC 100433 Haloalkane dehalogenase HLDIII dhmA DgarA Gordonia araii NBRC 100433
9eury-j3a357 Halogranum salarium B-1 Haloalkane dehalogenase HLDIII DhsA Halogranum salarium B-1
9alte-k7apw6 Paraglaciecola psychrophila 170 Haloalkane dehalogenase HLD1 DppsA Paraglaciecola psychrophila 170
9sphn-a3wc35 Erythrobacter sp. NAP1 Haloalkane dehalogenase HLD1 DexA Erythrobacter sp. NAP1
9rhob-a0a2t6cbq8 Sulfitobacter mediterraneus Haloalkane dehalogenase HLD1 DsmA Sulfitobacter mediterraneus
9gamm-DtacA Thalassomonas actiniarum Haloalkane dehalogenase HLD1 DtacA Thalassomonas actiniarum
9eury-a0a1i6hey7 Halogeometricum limi Haloalkane dehalogenase HLDIII DhliA Halogeometricum limi
9eury-m0il93 Haloferax mucosum ATCC BAA-1512 Haloalkane dehalogenase HLDIII DhmuA Haloferax mucosum ATCC BAA-1512
9actn-l7fa57 Streptomyces turgidiscabies Car8 Haloalkane_dehalogenase HLD1 DstA Streptomyces turgidiscabies Car8
9alte-k6xnl5 Paraglaciecola agarilytica NO2 Haloalkane dehalogenase 1 dhmA1 DpaA Paraglaciecola agarilytica NO2
chlad-b8g485 Chloroflexus aggregans (strain MD-66 \/ DSM 9485) Haloalkane dehalogenase HLDIII DcagA Chloroflexus aggregans
isopi-e8r367 Isosphaera pallida (strain ATCC 43644 \/ DSM 9630 \/ IS1B) Alpha\/beta hydrolase fold protein Isosphaera pallida
sacvd-DsvA Saccharomonospora viridis Haloalkane dehalogenase with unusual catalytic residues Saccharomonospora viridis
9acto-d1xj60 Streptomyces sp. ACTE Alpha\/beta hydrolase fold protein Streptomyces sp. ACTE
9alte-a3jb27 Marinobacter sp. ELB17 psychrophilic bacterium paradoxically high thermostability haloalkane dehalogenase DmxA Marinobacter sp. ELB17
9bact-q4pk85 uncultured bacterium MedeBAC35C06 predicted haloalkane dehalogenase uncultured bacterium MedeBAC35C06
9burk-q4b2v7 Polaromonas sp. JS666 binding region Polaromonas sp. JS666
9delt-a6g7b1 Plesiocystis pacifica SIR-1 Haloalkane dehalogenase, putative Plesiocystis pacifica SIR-1
9delt-a6ge89 Plesiocystis pacifica SIR-1 Alpha\/beta hydrolase Plesiocystis pacifica SIR-1
9gamm-a0ydx7 marine gamma proteobacterium HTCC2143 Haloalkane dehalogenase marine gamma proteobacterium HTCC2143
9gamm-a0yei4 marine gamma proteobacterium HTCC2143 Haloalkane dehalogenase marine gamma proteobacterium HTCC2143
9gamm-a0z6e4 marine gamma proteobacterium HTCC2080 Haloalkane dehalogenase HLD1 DmgaA marine gamma proteobacterium HTCC2080
9gamm-a0z8c8 marine gamma proteobacterium HTCC2080 Haloalkane dehalogenase marine gamma proteobacterium HTCC2080
9gamm-a0z514 marine gamma proteobacterium HTCC2080 Alpha\/beta hydrolase marine gamma proteobacterium HTCC2080
9gamm-b7ry85 marine gamma proteobacterium HTCC2148 Hydrolase, alpha\/beta fold family, putative marine gamma proteobacterium HTCC2148
9gamm-m4ukz1 Psychromonas sp. CNPT3 hydrolase, Haloalkane_dehalogenase HLDIII Psychromonas sp. CNPT3
9gamm-q1mz21 Oceanobacter sp. RED65 haloalkane dehalogenase (EC Oceanobacter sp. RED65
9gamm-q1yua3 marine gamma proteobacterium HTCC2207 haloalkane dehalogenase (EC marine gamma proteobacterium HTCC2207
9rhiz-a9dhk5 Hoeflea phototrophica DFL-43 Haloalkane dehalogenase Hoeflea phototrophica DFL-43
9rhob-a3x6y8 Roseobacter sp. MED193 Haloalkane dehalogenase Roseobacter sp. MED193
9rhob-b9nvf3 Rhodobacteraceae bacterium KLH11 Haloalkane dehalogenase Rhodobacteraceae bacterium KLH11
9sphn-q2nc04 Erythrobacter litoralis HTCC2594 haloalkane dehalogenase, putative Erythrobacter litoralis HTCC2594
artat-a1r682 Arthrobacter aurescens (strain TC1) putative hydrolase\/amp-binding domain protein Arthrobacter aurescens
aspcl-a1c8q9 Aspergillus clavatus (strain ATCC 1007 \/ CBS 513.65 \/ DSM 816 \/ NCT 3887 \/ NRRL 1) Haloalkane dehalogenase family protein Aspergillus clavatus
aspfc-b0yaj6 Neosartorya fumigata (strain CEA10 \/ CBS 144.89 \/ FGSC A1163) (Aspergillus fumigatus) Haloalkane dehalogenase family protein Neosartorya fumigata
aspfu-q4wbb4 Aspergillus fumigatus Af293 haloalkane dehalogenase family protein Aspergillus fumigatus Af293
aspnc-a2r4c0 Aspergillus nige Catalytic Epoxide hydrolase Aspergillus niger
burch-a0azu1 Burkholderia cenocepacia (strains AU 1054\; HI2424\; MC0-3) Burkholderia sp. (strain 383) Haloalkane_dehalogenase HLDIII Burkholderia cenocepacia
catad-c7pwp0 Catenulispora acidiphila (strain DSM 44928 \/ NRRL B-24433 \/ NBR 102108 \/ JCM 14897) Alpha\/beta hydrolase fold protein Catenulispora acidiphila
caucr-CC1175 Caulobacter crescentus (and strain NA1000\/CB15N)haloalkane dehalogenase, putative DccA Caulobacter crescentus
causk-dhma Caulobacter sp. (strain K31) Haloalkane dehalogenase Caulobacter sp.
chlaa-a9wa35 Chloroflexus aurantiacus (strains TCC 29366\/DSM635\/J-10-fl\; ATCC29364\/DSM637\/Y-400-fl) Haloalkane_dehalogenase HLDIII Chloroflexus aurantiacus
colp3-q482y8 Colwellia psychrerythraea (strain 34H \/ ATCC BAA-681) (Vibrio psychroerythus) Haloalkane_dehalogenase HLDIII Colwellia psychrerythraea
conwi-d3f899 Conexibacter woesei (strain DSM 14684 \/ JCM 11494 \/ NBRC 100937 \/ ID131577) Alpha\/beta hydrolase fold protein Conexibacter woesei
coxbu-CBU1225 Coxiella burnetii 1,3,4,6-tetrachloro-1,4-cyclohexadiene hydrolase hydrolase, alpha\/beta hydrolase fold family Coxiella burnetii
desac-q1k1k2 Desulfuromonas acetoxidans DSM 684 Haloalkane_dehalogenase HLDIII Desulfuromonas acetoxidans DSM 684
emeni-q5b9i0 Aspergillus nidulans FGSC A4 Haloalkane dehalogenase family protein (AFU_orthologue\; AFUA_8G01700) Aspergillus nidulans FGSC A4
geoog-d2s432 Geodermatophilus obscurus (strain ATCC 25078 \/ DSM 43160 \/ JCM 3152 \/ G-20) Alpha\/beta hydrolase fold protein Geodermatophilus obscurus
geour-a5gfj4 Geobacter uraniumreducens Rf4 hydrolase, Haloalkane_dehalogenase HLDIII Geobacter uraniumreducens Rf4
hahch-q2sav4 Hahella chejuensis (strain KCTC 2396) Haloalkane_dehalogenase HLDIII Hahella chejuensis
jansc-q28p20 Jannaschia sp. (strain CCS1) Haloalkane_dehalogenase HLDIII Jannaschia sp. CCS1
jansc-q28p25 Jannaschia sp. (strain CCS1) alpha\/beta hydrolase precursor Jannaschia sp. CCS1
kinra-q40yv4 Kineococcus radiotolerans SRS30216 alpha\/beta hydrolase fold:amp-dependent synthetase and ligase Kineococcus radiotolerans SRS30216
krifd-d2pqu1 Kribbella flavida (strain DSM 17836 \/ JCM 10339 \/ NBRC 14399) Alpha\/beta hydrolase fold protein Kribbella flavida
marhy-h8w685 Marinobacter hydrocarbonoclasticus\; Marinobacter aquaeolei VT8\; Marinobacter sp. Haloalkane dehalogenase Marinobacter hydrocarbonoclasticus VT8
mycav-DHMA Mycobacterium avium Mycobacterium paratuberculosis\; Mycobacterium sp.\; Mycobacterium tuberculosis haloalkane dehalogenase Mycobacterium paratuberculosis
mycmm-dhma Mycobacterium marinum\; Mycobacterium sp. Haloalkane dehalogenase Mycobacterium marinum
mycpa-q744j6 Mycobacterium paratuberculosis Mycobacterium avium (strain 104) hypothetical protein Mycobacterium paratuberculosis
mycs2-a0r5u5 Mycobacterium smegmatis (strain ATCC 700084 \/ mc(2)155) Haloalkane dehalogenase 1 Mycobacterium smegmatis
mycsk-a1un18 Mycobacterium sp. Alpha\/beta hydrolase fold protein Mycobacterium sp.
myctu-Rv1833c Mycobacterium tuberculosis, Mycobacterium bovis, hypothetical protein Rv1833c Haloalkane_dehalogenase HLDIII, DmbC, dhmA2 Rv1833c Mycobacterium tuberculosis
myctu-RV2296 Mycobacterium tuberculosis, Mycobacterium bovis, Mycobacterium africanum, Mycobacterium canettii DHA1 DHMA1 RV2296 gene Mycobacterium tuberculosis
mycua-a0psi2 Mycobacterium ulcerans (strain Agy99) Mycobacterium marinum (strain ATCC BAA-535 \/ M) Haloalkane dehalogenase Mycobacterium ulcerans
neofi-a1dal8 Neosartorya fischeri (strain ATCC 1020 \/ DSM 3700 \/ FGSC A1164 \/ NRR 181) (Aspergillus fischerianus) Haloalkane dehalogenase family protein Neosartorya fischeri
nocfa-q5ywh1 Nocardia farcinica Haloalkane_dehalogenase HLDIII Nocardia farcinica
paesj-c6cxk3 Paenibacillus sp. (strain JDR-2) Alpha\/beta hydrolase fold protein Paenibacillus sp.
parl1-a7htj7 Parvibaculum lavamentivorans (strain DS-1 \/ DSM 13023 \/ NCIMB 13966) Alpha\/beta hydrolase fold Parvibaculum lavamentivorans
pepld-a1atm7 Pelobacter propionicus DSM 2379 Haloalkane_dehalogenase HLDIII Pelobacter propionicus DSM 2379
phezh-dhma Phenylobacterium zucineum (strain HLK1) Haloalkane dehalogenase Phenylobacterium zucineum
phopr-Q93CH1 Photobacterium profundum (Photobacterium sp. (strain SS9))(and strain 3TCK) putative haloalkane dehalogenase HLDIII DpproA Photobacterium profundum
psyck-q1qbb9 Psychrobacter cryohalolentis, Psychrobacter sp., alpha\/beta hydrolase fold Psychrobacter cryohalolentis
psyin-a1sw98 Psychromonas ingrahamii (strain 37) hydrolase, Haloalkane_dehalogenase Psychromonas ingrahamii
rhil3-q1m5k0 Rhizobium leguminosarum bv. viciae (strain 3841) bv. trifolii (strain WSM1325) putative haloalkane dehalogenase Rhizobium leguminosarum bv. viciae
rhoba-DHLA Rhodopirellula baltica haloalkane dehalogenase (EC HLDIII DHLA DrbA Rhodopirellula baltica
rhoer-c3jvx6 Rhodococcus erythropolis (strains SK121\; PR4 \/ NBRC 100887) Haloalkane dehalogenase Rhodococcus erythropolis SK121
salrd-q2s473 Salinibacter ruber (strain DSM 13855) haloalkane dehalogenase HLDIII Salinibacter ruber
serod-d4e081 Serratia odorifera DSM 4582 1,3,4,6-tetrachloro-1,4-cyclohexadiene hydrolase Serratia odorifera DSM 4582
sheam-a1s4t4 Shewanella amazonensis (strain ATCC BAA-1098 \/ SB2B) Haloalkane_dehalogenase HLDIII Shewanella amazonensis SB2B
shedo-q12ph0 Shewanella denitrificans OS217 Haloalkane_dehalogenase HLDIII Shewanella denitrificans OS217
shefr-q3nsz6 Shewanella frigidimarina NCIMB 400 haloalkane dehalogenase (EC Shewanella frigidimarina NCIMB 400
shefr-q3nuz7 Shewanella frigidimarina NCIMB 400 Haloalkane_dehalogenase HLDIII Shewanella frigidimarina NCIMB 400
shelp-a3qdn3 Shewanella loihica (strain ATCCBAA-1088\/PV-4) Haloalkane_dehalogenase HLDIII Shewanella sp. PV-4
sheon-SO1743 Shewanella oneidensis (Shewanella sp. MR-4\; MR-7\; ANA-3\; Shewanella baltica (strain OS155 \/ ATCC BAA-1091) hydrolase, Haloalkane_dehalogenase HLDIII Shewanella oneidensis
shesw-a1rld1 Shewanella sp. W3-18-1 Shewanella baltica OS155 Shewanella putrefaciens (strains 200\; CN-32\/ATCC\/BAA-453) Haloalkane_dehalogenase HLDIII Shewanella baltica OS155
sorc5-a9fvz2 Sorangium cellulosum (strain So ce56) (Polyangium cellulosum (strain So ce56)) Haloalkane dehalogenase Sorangium cellulosum
strav-SAV4779 Streptomyces avermitilis putative haloalkane dehalogenase Streptomyces avermitilis
strrd-d2auf6 Streptosporangium roseum (strain ATCC 12428 \/ DSM 43021 \/ JCM 3005 \/ NI 9100) Haloalkane dehalogenase Streptosporangium roseum
strrd-d2ba59 Streptosporangium roseum (strain ATCC 12428 \/ DSM 43021 \/ JCM 3005 \/ NI 9100) Haloalkane dehalogenase Streptosporangium roseum
strrd-d2be60 Streptosporangium roseum (strain ATCC 12428 \/ DSM 43021 \/ JCM 3005 \/ NI 9100) Alpha\/beta hydrolase fold protein Streptosporangium roseum
xanau-halo1 Xanthobacter autotrophicus, Xanthobacter flavus, Ancylobacter aquaticus, haloalkane dehalogenase DhlA Xanthobacter autotrophicus
xanax-DHAA Xanthomonas axonopodis (pv. citri) Xanthomonas campestris (pv. campestris (strains 8004\; B100\; 85-10\; vesicatoria ATCC 35937), pv. vesicatoria (strain 85-10)) haloalkane dehalogenase HLDIII Xanthomonas axonopodis
miclc-OleB Micrococcus luteus (Micrococcus lysodeikticus) beta-lactone decarboxylase, haloalkane dehalogenase HLD-III OleB from OleBC fusion Mlut_13240 Micrococcus luteus
xancp-OleB Xanthomonas campestris beta-lactone decarboxylase, haloalkane dehalogenase HLD-III OleB Xanthomonas campestris
xanor-q5gv06 Xanthomonas oryzae pv. oryzae (and strain MAFF 311018) haloalkane dehalogenase HLDIII Xanthomonas oryzae pv. oryzae
xylfa-XF1965 Xylella fastidiosa(strains Ann-1\; Dixon\; Temecula-1\; M-12) haloalkane dehalogenase HLDIII Xylella fastidiosa
9bact-v5ln96 uncultured bacterium Haloalkane dehalogenase Cluster B eHLD-B uncultured bacterium
9alte-g6yut5 Marinobacter manganoxydans\; Marinobacter adhaerens Haloalkane dehalogenase Marinobacter manganoxydans MnI7-9
9gamm-b4wzn0 Alcanivorax sp. DG881. Haloalkane dehalogenase Alcanivorax sp. DG881
9bact-v5llk8 uncultured bacterium. Haloalkane dehalogenase dhmA uncultured bacterium
9alte-r8b4s5 Marinobacter lipolyticus SM19. Haloalkane dehalogenase Marinobacter lipolyticus SM19
9actn-m5a3u3 Ilumatobacter coccineus YM16-304. Haloalkane dehalogenase Ilumatobacter coccineus YM16-304
9myco-d5p7l8 Mycobacterium parascrofulaceum ATCC BAA-614. Haloalkane dehalogenase Mycobacterium parascrofulaceum ATCC BAA-614
9myco-i2acb5 Mycobacterium sp. Mycobacterium intracellulare\; Mycobacterium avium\; Mycobacterium yongonense\; Mycobacterium indicus pranii, Haloalkane dehalogenase Mycobacterium sp. MOTT36Y
mycka-x7yty4 Mycobacterium kansasii\; Mycobacterium gastri Haloalkane dehalogenase Mycobacterium kansasii 732
9myco-a0a024k1j2 Mycobacterium triplex. Haloalkane dehalogenase Mycobacterium triplex
9myco-j5ee32 Mycobacterium colombiense\; Mycobacterium tuberculosis\; Haloalkane dehalogenase Mycobacterium colombiense CECT 3035
9alte-a6ex60 Marinobacter algicola DG893. Haloalkane dehalogenase Marinobacter algicola DG893
9gamm-u7g0y8 Alcanivorax sp. P2S70. Haloalkane dehalogenase Alcanivorax sp. P2S70
9bact-v5llz0 uncultured bacterium. Haloalkane dehalogenase uncultured bacterium
9alte-a6f419 Marinobacter algicola DG893. Haloalkane dehalogenase Marinobacter algicola DG893
9alte-r8ayh5 Marinobacter lipolyticus SM19. Haloalkane dehalogenase Marinobacter lipolyticus SM19
9acto-k6wlp4 Gordonia rhizosphera NBRC 16068. Haloalkane dehalogenase Gordonia rhizosphera NBRC 16068
9alte-m7crb9 Marinobacter santoriniensis NKSG1. Haloalkane dehalogenase Marinobacter santoriniensis NKSG1
9alte-n6w2r7 Marinobacter nanhaiticus D15-8W. Haloalkane dehalogenase Marinobacter nanhaiticus D15-8W
caust-d5vky2 Caulobacter segnis (strain ATCC 21756 \/ DSM 7131 \/ JCM 7823 \/ NBRC 15250 \/ LMG 17158 \/ TK0059) (Mycoplana segnis). Haloalkane dehalogenase Caulobacter segnis
cauce-r0el45 Caulobacter crescentus OR37. Haloalkane dehalogenase Caulobacter crescentus OR37
9gamm-l0wcp3 Alcanivorax hongdengensis A-11-3. Haloalkane dehalogenase Alcanivorax hongdengensis A-11-3
mycav-t2gun3 Mycobacterium avium \; Mycobacterium gordonae\; Mycobacteroides franklinii. Haloalkane dehalogenase HLD1 dhmA DmgoA Mycobacterium avium subsp. hominissuis TH135
mycrh-g4i2j6 Mycobacterium rhodesiae JS60. Haloalkane dehalogenase Mycobacterium rhodesiae JS60
9myco-a0a064c9r1 Mycobacterium aromaticivorans JS19b1 = JCM 16368. Haloalkane dehalogenase Mycobacterium aromaticivorans JS19b1 = JCM 16368
mycvp-a1t7p8 Mycobacterium vanbaalenii (strain DSM 7251 \/ PYR-1). Alpha\/beta hydrolase fold protein Mycobacterium vanbaalenii
mycsr-e6tfi3 Mycobacterium sp. (strain Spyr1). Predicted hydrolase or acyltransferase of alpha\/beta superfamily Mycobacterium sp.
9myco-w9blw9 Mycobacterium cosmeticum. Hydrolase or acyltransferase of alpha\/beta superfamily protein Mycobacterium cosmeticum
mycav-x7u1u9 Mycobacterium avium MAV_120709_2344. Haloalkane dehalogenase Mycobacterium avium MAV_120709_2344
mycav-x7ubn6 Mycobacterium avium MAV_120709_2344. Haloalkane dehalogenase Mycobacterium avium MAV_120709_2344
9psed-a0a0a1yq19 Pseudomonas taeanensis MS-3. Haloalkane dehalogenase Pseudomonas taeanensis MS-3
blasd-h6rk89 Blastococcus saxobsidens (strain DD2). Haloalkane dehalogenase Blastococcus saxobsidens
9noca-w8a428 Nocardia seriolae N-2927. Haloalkane dehalogenase Nocardia seriolae N-2927
shefn-q082b3 Shewanella frigidimarina (strain NCIMB 400). Alpha\/beta hydrolase fold Shewanella frigidimarina
9acto-a0a098ye08 Modestobacter sp. KNN45-2b. Haloalkane dehalogenase Modestobacter sp. KNN45-2b
9alte-k6y704 Glaciecola arctica BSs20135. Haloalkane dehalogenase Glaciecola arctica BSs20135
9chlr-d6tye6 Ktedonobacter racemifer DSM 44963. Alpha\/beta hydrolase fold protein Ktedonobacter racemifer DSM 44963
9spio-a0a0a0e285 Spirochaeta sp. JC202. Haloalkane dehalogenase Spirochaeta sp. JC202
psea6-q15uk5 Pseudoalteromonas atlantica (strain T6c \/ ATCC BAA-1087). Alpha\/beta hydrolase fold familiy Pseudoalteromonas atlantica

Gene_locus_frgt Name Species
9burk-q4lgc1 Burkholderia cenocepacia HI2424, Rhodoferax ferrireducens (strain DSM 15236 \/ ATCC BAA-621 \/ T118)cytidine\/deoxycytidylate deaminase, zinc-binding region Burkholderia cenocepacia

Substrate Chemical Nomenclature Proteins
Mustard-gas 1-chloro-2-(2-chloroethylsulfanyl)ethane xanau-halo1
1,3,4,6-Tetrachloro-1,4-cyclohexadiene 1,3,4,6-tetrachlorocyclohexa-1,4-diene myctu-linb    sphpi-linb
Lindane 1,2,3,4,5,6-hexachlorocyclohexane myctu-linb    sphpi-linb    sphpi-q6vqx3
1-Chlorobutane 1-chlorobutane agrtu-DHAA    brael-e2rv62    braja-dhaa    myctu-linb    myctu-Rv1833c    rhoba-DHLA    rhoso-halo1    sphpi-linb    xanau-halo1
1-Chlorohexane 1-chlorohexane agrtu-DHAA    brael-e2rv62    braja-dhaa    myctu-linb    myctu-Rv1833c    rhoba-DHLA    rhoso-halo1    sphpi-linb    xanau-halo1
1-Bromobutane 1-bromobutane agrtu-DHAA    brael-e2rv62    braja-dhaa    myctu-linb    myctu-Rv1833c    rhoba-DHLA    rhoso-halo1    sphpi-linb    xanau-halo1
1-Iodopropane 1-iodopropane agrtu-DHAA    brael-e2rv62    braja-dhaa    myctu-linb    myctu-Rv1833c    rhoba-DHLA    rhoso-halo1    sphpi-linb    xanau-halo1
1-Iodohexane 1-iodohexane agrtu-DHAA    brael-e2rv62    braja-dhaa    myctu-linb    myctu-Rv1833c    rhoba-DHLA    rhoso-halo1    sphpi-linb    xanau-halo1
1-Iodobutane 1-iodobutane agrtu-DHAA    brael-e2rv62    braja-dhaa    myctu-linb    myctu-Rv1833c    rhoba-DHLA    rhoso-halo1    sphpi-linb    xanau-halo1
1,3-dichloropropane 1,3-dichloropropane agrtu-DHAA    brael-e2rv62    braja-dhaa    myctu-linb    myctu-Rv1833c    rhoba-DHLA    rhoso-halo1    sphpi-linb    xanau-halo1
1,5-dichloropentane 1,5-dichloropentane agrtu-DHAA    brael-e2rv62    braja-dhaa    myctu-linb    myctu-Rv1833c    rhoba-DHLA    rhoso-halo1    sphpi-linb    xanau-halo1
1-Bromo-3-Chloropropane 1-bromo-3-chloropropane agrtu-DHAA    brael-e2rv62    braja-dhaa    myctu-linb    myctu-Rv1833c    rhoba-DHLA    rhoso-halo1    sphpi-linb    xanau-halo1
1,3-diiodopropane 1,3-diiodopropane agrtu-DHAA    brael-e2rv62    braja-dhaa    myctu-linb    myctu-Rv1833c    rhoba-DHLA    rhoso-halo1    sphpi-linb    xanau-halo1
2-Iodobutane 2-iodobutane agrtu-DHAA    brael-e2rv62    braja-dhaa    myctu-linb    myctu-Rv1833c    rhoba-DHLA    rhoso-halo1    sphpi-linb    xanau-halo1
2-Bromo-1-Chloropropane 2-bromo-1-chloropropane agrtu-DHAA    brael-e2rv62    braja-dhaa    myctu-linb    myctu-Rv1833c    rhoba-DHLA    rhoso-halo1    sphpi-linb    xanau-halo1
1-Chloro-2-(2-chloroethoxy)ethane 1-chloro-2-(2-chloroethoxy)ethane agrtu-DHAA    brael-e2rv62    braja-dhaa    myctu-linb    myctu-Rv1833c    rhoba-DHLA    rhoso-halo1    sphpi-linb    xanau-halo1
Chlorocyclohexane chlorocyclohexane agrtu-DHAA    brael-e2rv62    braja-dhaa    myctu-linb    myctu-Rv1833c    rhoba-DHLA    rhoso-halo1    sphpi-linb    xanau-halo1
Bromocyclohexane bromocyclohexane agrtu-DHAA    brael-e2rv62    braja-dhaa    myctu-linb    myctu-Rv1833c    rhoba-DHLA    rhoso-halo1    sphpi-linb    xanau-halo1
(Bromomethyl)cylcohexane bromomethylcyclohexane agrtu-DHAA    brael-e2rv62    braja-dhaa    myctu-linb    myctu-Rv1833c    rhoba-DHLA    rhoso-halo1    sphpi-linb    xanau-halo1
1-Bromo-2-chloroethane 1-bromo-2-chloroethane agrtu-DHAA    brael-e2rv62    braja-dhaa    myctu-linb    myctu-Rv1833c    rhoba-DHLA    rhoso-halo1    sphpi-linb    xanau-halo1
Chlorocyclopentane chlorocyclopentane agrtu-DHAA    brael-e2rv62    braja-dhaa    myctu-linb    myctu-Rv1833c    rhoba-DHLA    rhoso-halo1    sphpi-linb    xanau-halo1
4-Bromobutanenitrile 4-bromobutanenitrile agrtu-DHAA    brael-e2rv62    braja-dhaa    myctu-linb    myctu-Rv1833c    rhoba-DHLA    rhoso-halo1    sphpi-linb    xanau-halo1
1,2,3-Tribromopropane 1,2,3-tribromopropane agrtu-DHAA    brael-e2rv62    braja-dhaa    myctu-linb    myctu-Rv1833c    rhoba-DHLA    rhoso-halo1    sphpi-linb    xanau-halo1
1,2-Dibromo-3-Chloropropane 1,2-dibromo-3-chloropropane agrtu-DHAA    brael-e2rv62    braja-dhaa    myctu-linb    myctu-Rv1833c    rhoba-DHLA    rhoso-halo1    sphpi-linb    xanau-halo1
3-Chloro-2-methylprop-1-ene 3-chloro-2-methylprop-1-ene agrtu-DHAA    brael-e2rv62    braja-dhaa    myctu-linb    myctu-Rv1833c    rhoba-DHLA    rhoso-halo1    sphpi-linb    xanau-halo1
2,3-Dichloroprop-1-ene 2,3-dichloroprop-1-ene agrtu-DHAA    brael-e2rv62    braja-dhaa    myctu-linb    myctu-Rv1833c    rhoba-DHLA    rhoso-halo1    sphpi-linb    xanau-halo1
2,3-dibromopropene 2,3-dibromoprop-1-ene sphpi-linb
1,2-dichloropropane (2S)-2,3-dichloropropan-1-ol sphpi-linb    braja-dhaa
1,2-dibromopropane 1,2-dibromopropane agrtu-DHAA    brael-e2rv62    braja-dhaa    myctu-linb    myctu-Rv1833c    rhoba-DHLA    rhoso-halo1    sphpi-linb    xanau-halo1
1-bromohexane 1-bromohexane 9rhob-KF032932    agrtu-DHAA    brael-e2rv62    braja-dhaa    myctu-linb    myctu-Rv1833c    rhoba-DHLA    rhoso-halo1    sphpi-linb    xanau-halo1
1,3-dibromopropane 1,3-dibromopropane myctu-linb    agrtu-DHAA    brael-e2rv62    braja-dhaa    myctu-Rv1833c    rhoba-DHLA    rhoso-halo1    sphpi-linb    xanau-halo1
1,2-dibromoethane 1,2-dibromoethane agrtu-DHAA    brael-e2rv62    braja-dhaa    myctu-linb    myctu-Rv1833c    rhoba-DHLA    rhoso-halo1    sphpi-linb    xanau-halo1
1,2-dichloroethane 1,2-dichloroethane sphpi-linb    agrtu-DHAA    brael-e2rv62    braja-dhaa    myctu-Rv1833c    rhoba-DHLA    rhoso-halo1    xanau-halo1

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Gene_locus related to this paper: xanau-halo1