Hepatic_Lipase
Relationship
Comment
Pancreatic, hepatic and gastric/lingual lipase are closely related to each other and to lipoprotein lipase (EC: 3.1.1.34), which hydrolyses triglycerides of chylomicrons and very low density lipoproteins (VLDL). Familial human hepatic lipase deficiency is a rare recessive disorder Two variants (S267F and T383M) are rare mutations found to date only in HL deficient subjects and their relatives. Of the six HL variants described to date, only S267F and T383M are associated with hyperlipidemia. human-LIPC. The disease is characterised by premature atherosclerosis and abnormal circulating lipoproteins
Database
Interpro : IPR000734 Lipase , IPR002333 Hepatic lipase , IPR016272 Lipase, LIPH-type , IPR013818 Lipase
PIRSF : No PIRSF
Pdoc : PDOC00110
Pfam : PF00151 Lipase
Prints : PR00821 , PR00824
EC Number : 3.1.1.3
Sequences
| Peptide in | Fasta |
| Nucleotide in | Fasta |
| Alignment with Multalin | Text only |
| Seed alignment with MAFFT | No colour / coloured with Mview |
| Alignment with MAFFT | No colour / coloured with Mview |
| Dendrogram | The dnd file |
| Gene_locus | Name | Species |
|---|---|---|
| 9ceta-a0a341cs64 | Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise). hepatic triacylglycerol lipase | Neophocaena asiaeorientalis asiaeorientalis |
| 9pase-a0a218umy7 | Lonchura striata domestica (Bengalese finch). Hepatic triacylglycerol lipase | Lonchura striata domestica |
| 9scom-a0a1p8bn28 | Pampus argenteus (silver pomfret). Hepatic lipase | Pampus argenteus |
| 9tele-a0a0p7urp3 | Scleropages formosus (Asian bonytongue). Hepatic lipase-like | Scleropages formosus |
| 9tele-a0a0s7ljd0 | Poeciliopsis prolifica (blackstripe livebearer). LIPC | Poeciliopsis prolifica |
| 9tele-a0a1w4zev7 | Scleropages formosus (Asian bonytongue). hepatic triacylglycerol lipase | Scleropages formosus |
| 9tele-a0a2i4css4 | Austrofundulus limnaeus. hepatic triacylglycerol lipase | Austrofundulus limnaeus |
| acibe-a0a075ekg6 | Acipenser baerii (Siberian sturgeon)\; Acipenser sinensis (Chinese sturgeon)\; Acipenser schrenckii (Amur sturgeon). Hepatic lipase | Acipenser baerii |
| ailme-g1l8s9 | Ailuropoda melanoleuca (Giant panda). Uncharacterized protein | Ailuropoda melanoleuca |
| allmi-a0a151ma81 | Alligator mississippiensis (American alligator). Hepatic triacylglycerol lipase | Alligator mississippiensis |
| allsi-a0a1u8d805 | Alligator sinensis (Chinese alligator). hepatic triacylglycerol lipase | Alligator sinensis |
| amaae-a0a0q3u653 | Amazona aestiva (Blue-fronted Amazon parrot). Hepatic triacylglycerol lipase | Amazona aestiva |
| anapl-r0kv25 | Anas platyrhynchos (Mallard) (Anas boschas). Hepatic triacylglycerol lipase | Anas platyrhynchos |
| angan-a0a0e9xfs5 | Anguilla anguilla (European freshwater eel) (Muraena anguilla). Uncharacterized protein | Anguilla anguilla |
| angja-d3tjk5 | Anguilla japonica (Japanese eel). Hepatic lipase | Anguilla japonica |
| anoca-h9glr3 | Anolis carolinensis (Green anole) (American chameleon). Lipase C, hepatic type | Anolis carolinensis |
| aotna-a0a2k5e885 | Aotus nancymaae (Ma's night monkey). Lipase C, hepatic type | Aotus nancymaae |
| aptfo-a0a087r466 | Aptenodytes forsteri (Emperor penguin). Hepatic triacylglycerol lipase | Aptenodytes forsteri |
| astmx-w5kyj0 | Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus). Lipase, hepatic a | Astyanax mexicanus |
| astmx-w5l5v5 | Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus). Lipase C, hepatic type | Astyanax mexicanus |
| balas-a0a383ysz3 | Balaenoptera acutorostrata scammoni (North Pacific minke whale) (Balaenoptera davidsoni). hepatic triacylglycerol lipase | Balaenoptera acutorostrata scammoni |
| balre-a0a087vi69 | Balearica regulorum gibbericeps (East African grey crowned-crane). Hepatic triacylglycerol lipase | Balearica regulorum gibbericeps |
| bovin-q3sz79 | Bos taurus (Bovine)\; Bos mutus grunniens (Wild yak) (Bos grunniens) lipase, hepatic | Bos taurus |
| canlf-f1pcc4 | Canis lupus familiaris (Dog) (Canis familiaris). Lipase C, hepatic type | Canis lupus familiaris |
| cavpo-h0v1p4 | Cavia porcellus (Guinea pig). Lipase C, hepatic type | Cavia porcellus |
| cebca-a0a2k5p9a2 | Cebus capucinus imitator. Lipase C, hepatic type | Cebus capucinus imitator |
| cerat-a0a2k5n7v1 | Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys). Lipase C, hepatic type | Cercocebus atys |
| chick-f1nzi7 | Gallus gallus (Chicken). Lipase C, hepatic type | Gallus gallus |
| chlsb-a0a0d9rhr8 | Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus). Lipase C, hepatic type | Chlorocebus sabaeus |
| colap-a0a2k5i0f1 | Colobus angolensis palliatus (Peters' Angolan colobus). Lipase C, hepatic type | Colobus angolensis palliatus |
| colli-a0a2i0m6q6 | Columba livia (Rock dove). Lipase, hepatic | Columba livia |
| crigr-g3grm1 | Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus). Hepatic triacylglycerol lipase | Cricetulus griseus |
| cypca-s4s6y9 | Cyprinus carpio 'jian' (Jian carp). Lipase | Cyprinus carpio |
| danre-q7t359 | Danio rerio (Zebrafish) (Brachydanio rerio) similar to lipase, hepatic | Danio rerio |
| delle-a0a2y9nju6 | Delphinapterus leucas (Beluga whale). hepatic triacylglycerol lipase isoform X2 | Delphinapterus leucas |
| dipor-a0a1s3epj6 | Dipodomys ordii (Ord's kangaroo rat). hepatic triacylglycerol lipase | Dipodomys ordii |
| enhlu-a0a2y9k425 | Enhydra lutris kenyoni (northern sea otter). hepatic triacylglycerol lipase | Enhydra lutris kenyoni |
| epico-d3tjh4 | Epinephelus coioides (Orange-spotted grouper) (Epinephelus nebulosus). Hepatic lipase | Epinephelus coioides |
| erieu-a0a1s3wpe9 | Erinaceus europaeus (Western European hedgehog). hepatic triacylglycerol lipase | Erinaceus europaeus |
| felca-m3w8t2 | Felis catus (Cat) (Felis silvestris catus). Lipase C, hepatic type | Felis catus |
| fical-u3kcn1 | Ficedula albicollis (Collared flycatcher) (Muscicapa albicollis). Lipase C, hepatic type | Ficedula albicollis |
| fukda-a0a091d1s6 | Fukomys damarensis (Damaraland mole rat) (Cryptomys damarensis). Hepatic triacylglycerol lipase | Fukomys damarensis |
| funhe-a0a147ar95 | Fundulus heteroclitus (Killifish) (Mummichog). Hepatic triacylglycerol lipase | Fundulus heteroclitus |
| gamaf-a0a315v5h8 | Gambusia affinis (Western mosquitofish) (Heterandria affinis). Uncharacterized protein | Gambusia affinis |
| gasac-g3pte3 | Gasterosteus aculeatus (Three-spined stickleback). Lipase, hepatic a | Gasterosteus aculeatus |
| gorgo-g3qyk3 | Gorilla gorilla gorilla (Western lowland gorilla). Lipase C, hepatic type | Gorilla gorilla gorilla |
| hetga-a0a0p6jx60 | Heterocephalus glaber (Naked mole rat). Hepatic triacylglycerol lipase | Heterocephalus glaber |
| horse-f6ti02 | Equus caballus (Horse). Lipase C, hepatic type | Equus caballus |
| human-LIPC | Homo sapiens (Human) LIPC hepatic triacylglycerol lipase HTGL | Homo sapiens |
| ictpu-a0a2d0q9u3 | Ictalurus punctatus (Channel catfish) (Silurus punctatus). hepatic triacylglycerol lipase | Ictalurus punctatus |
| ictpu-w5u9s1 | Ictalurus punctatus (Channel catfish) (Silurus punctatus). hepatic triacylglycerol lipase-like | Ictalurus punctatus |
| icttr-a0a287dba5 | Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus tridecemlineatus). Lipase C, hepatic type | Ictidomys tridecemlineatus |
| latch-h3anv5 | Latimeria chalumnae (West Indian ocean coelacanth). Lipase C, hepatic type | Latimeria chalumnae |
| lepoc-w5n813 | Lepisosteus oculatus (Spotted gar). Lipase, hepatic a | Lepisosteus oculatus |
| lepwe-a0a2u3xxl2 | Leptonychotes weddellii (Weddell seal). hepatic triacylglycerol lipase | Leptonychotes weddellii |
| limla-a0a2i0upj0 | Limosa lapponica baueri. Hepatic triacylglycerol lipase | Limosa lapponica baueri |
| lipve-a0a340xc08 | Lipotes vexillifer (Yangtze river dolphin). hepatic triacylglycerol lipase isoform X1 | Lipotes vexillifer |
| loxaf-g3ssk6 | Loxodonta africana (African elephant). Lipase C, hepatic type | Loxodonta africana |
| macfa-g7pbk1 | Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey). Hepatic triacylglycerol lipase | Macaca fascicularis |
| macmu-g7mxj6 | Macaca mulatta (Rhesus macaque). Hepatic triacylglycerol lipase | Macaca mulatta |
| macne-a0a2k6cdx5 | Macaca nemestrina (Pig-tailed macaque). Lipase C, hepatic type | Macaca nemestrina |
| manle-a0a2k5ycy8 | Mandrillus leucophaeus (Drill) (Papio leucophaeus). Lipase C, hepatic type | Mandrillus leucophaeus |
| melga-g1n1j3 | Meleagris gallopavo (Wild turkey). Lipase C, hepatic type | Meleagris gallopavo |
| mesau-a0a1u7qmu7 | Mesocricetus auratus (Golden hamster). hepatic triacylglycerol lipase isoform X2 | Mesocricetus auratus |
| mondo-f6pxq2 | Monodelphis domestica (Gray short-tailed opossum). Lipase C, hepatic type | Monodelphis domestica |
| mouse-1hlip | Mus musculus (Mouse), Mus spretus (Western Mediterranean mouse) (Algerian mouse) hepatic triacylglycerol lipase | Mus musculus |
| muspf-m3xz47 | Mustela putorius furo (European domestic ferret) (Mustela furo). Lipase C, hepatic type | Mustela putorius furo |
| myobr-s7nnt6 | Myotis brandtii (Brandt's bat). Hepatic triacylglycerol lipase | Myotis brandtii |
| myolu-g1q2n9 | Myotis lucifugus (Little brown bat). Lipase C, hepatic type | Myotis lucifugus |
| neosc-a0a2y9hdm5 | Neomonachus schauinslandi (Hawaiian monk seal) (Monachus schauinslandi). hepatic triacylglycerol lipase | Neomonachus schauinslandi |
| neovi-u6dl10 | Neovison vison (American mink) (Mustela vison). Lipase, hepatic | Neovison vison |
| nomle-g1rks1 | Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys). Lipase C, hepatic type | Nomascus leucogenys |
| odoro-a0a2u3znc0 | Odobenus rosmarus divergens (Pacific walrus). hepatic triacylglycerol lipase | Odobenus rosmarus divergens |
| ophha-v8pgg0 | Ophiophagus hannah (King cobra) (Naja hannah). Hepatic triacylglycerol lipase | Ophiophagus hannah |
| oreni-i3jeq5 | Oreochromis niloticus (Nile tilapia) (Tilapia nilotica). Lipase, hepatic a | Oreochromis niloticus |
| oryla-h2lw61 | Oryzias latipes (Japanese rice fish) (Japanese killifish). Lipase, hepatic a | Oryzias latipes |
| otoga-h0xrh5 | Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby). Lipase C, hepatic type | Otolemur garnettii |
| pagma-q0eda6 | Pagrus major (Red sea bream) (Chrysophrys major). Hepatic lipase | Pagrus major |
| panpa-a0a2r8z5s1 | Pan paniscus (Pygmy chimpanzee) (Bonobo). Lipase C, hepatic type | Pan paniscus |
| pantr-a0a2j8nse0 | Pan troglodytes (Chimpanzee). Lipase C, hepatic type | Pan troglodytes |
| papan-a0a096nm76 | Papio anubis (Olive baboon). Lipase C, hepatic type | Papio anubis |
| papan-a0a2i3lds2 | Papio anubis (Olive baboon). Lipase C, hepatic type | Papio anubis |
| patfa-a0a1v4jdn8 | Patagioenas fasciata monilis. Hepatic triacylglycerol lipase | Patagioenas fasciata monilis |
| pelsi-k7g6q6 | Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis). Lipase C, hepatic type | Pelodiscus sinensis |
| petma-s4rx12 | Petromyzon marinus (Sea lamprey). Lipase, hepatic b | Petromyzon marinus |
| phycd-a0a2y9t7d5 | Physeter catodon (Sperm whale) (Physeter macrocephalus). hepatic triacylglycerol lipase | Physeter catodon |
| pig-b8xsi5 | Sus scrofa (Pig). Hepatic lipase | Sus scrofa |
| poefo-a0a087y7j6 | Poecilia formosa (Amazon molly) (Limia formosa). Lipase, hepatic a | Poecilia formosa |
| poefo-a0a096lpw6 | Poecilia formosa (Amazon molly) (Limia formosa). Lipase, hepatic a | Poecilia formosa |
| ponab-a0a2j8vca8 | Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii). LIPC isoform 4 | Pongo abelii |
| proco-a0a2k6fr71 | Propithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi coquereli). Lipase C, hepatic type | Propithecus coquereli |
| rabit-1hlip | Oryctolagus cuniculus (Rabbit) Hepatic triacylglycerol lipase LIPH_RABI LIPC (hl) | Oryctolagus cuniculus |
| ratno-1hlip | Rattus norvegicus (Rat) Triacylglycerol lipase hepatic | Rattus norvegicus |
| rhibe-a0a2k6n5t9 | Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti)\; Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana). Lipase C, hepatic type | Rhinopithecus bieti |
| saibb-a0a2k6tew8 | Saimiri boliviensis boliviensis (Bolivian squirrel monkey). Lipase C, hepatic type | Saimiri boliviensis boliviensis |
| salsa-a0a1s3kus2 | Salmo salar (Atlantic salmon). LOW QUALITY PROTEIN: hepatic triacylglycerol lipase | Salmo salar |
| salsa-a0a1s3ptx4 | Salmo salar (Atlantic salmon). hepatic triacylglycerol lipase-like isoform X2 | Salmo salar |
| sarha-g3vv12 | Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius). Lipase C, hepatic type | Sarcophilus harrisii |
| sarha-g3vv13 | Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius). Lipase C, hepatic type | Sarcophilus harrisii |
| scomx-a0a2u9bct5 | Scophthalmus maximus (Turbot) (Psetta maxima). Hepatic lipase | Scophthalmus maximus |
| sheep-w5qi65 | Ovis aries (Sheep). Lipase C, hepatic type | Ovis aries |
| sinch-d3tjl1 | Siniperca chuatsi (Mandarin fish). Hepatic lipase | Siniperca chuatsi |
| souch-a0a1d8i1n4 | Sousa chinensis (Indo-pacific humpbacked dolphin) (Steno chinensis). Hepatic lipase | Sousa chinensis |
| spaau-e3nyp8 | Sparus aurata (Gilthead sea bream). Hepatic lipase | Sparus aurata |
| taegu-h0z6w2 | Taeniopygia guttata (Zebra finch) (Poephila guttata). Lipase C, hepatic type | Taeniopygia guttata |
| takru-h2v8t3 | Takifugu rubripes (Japanese pufferfish) (Fugu rubripes). Lipase, hepatic a | Takifugu rubripes |
| tarsy-a0a1u7sy37 | Tarsius syrichta (Philippine tarsier). hepatic triacylglycerol lipase | Tarsius syrichta |
| tetng-q4sie5 | Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon nigroviridis). Lipase, hepatic a | Tetraodon nigroviridis |
| trima-a0a2y9di71 | Trichechus manatus latirostris (Florida manatee). hepatic triacylglycerol lipase | Trichechus manatus latirostris |
| tupch-l9l8p0 | Tupaia chinensis (Chinese tree shrew). Hepatic triacylglycerol lipase | Tupaia chinensis |
| turtr-a0a2u4cb93 | Tursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus). hepatic triacylglycerol lipase | Tursiops truncatus |
| ursma-a0a384db38 | Ursus maritimus (Polar bear) (Thalarctos maritimus). hepatic triacylglycerol lipase | Ursus maritimus |
| xenla-a0a1l8gt68 | Xenopus laevis (African clawed frog). Uncharacterized protein | Xenopus laevis |
| xenla-a0a1l8h0b2 | Xenopus laevis (African clawed frog). Uncharacterized protein | Xenopus laevis |
| xentr-b0bmb8 | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis). Lipc protein | Xenopus tropicalis |
| xipma-m4a796 | Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus). Lipase, hepatic a | Xiphophorus maculatus |
| Gene_locus_frgt | Name | Species |
|---|---|---|
| 9aves-a0a091gi13 | Cuculus canorus (common cuckoo). Hepatic triacylglycerol lipase | Cuculus canorus |
| 9aves-a0a093c3v3 | Pterocles gutturalis (yellow-throated sandgrouse). Hepatic triacylglycerol lipase | Pterocles gutturalis |
| 9ceta-a0a1d8i1n5 | Neophocaena asiaeorientalis. Hepatic lipase | Neophocaena asiaeorientalis asiaeorientalis |
| 9grui-a0a091kpa2 | Chlamydotis macqueenii (Macqueen's bustard). Hepatic triacylglycerol lipase | Chlamydotis macqueenii |
| 9grui-a0a091re06 | Mesitornis unicolor (brown roatelo). Hepatic triacylglycerol lipase | Mesitornis unicolor |
| 9pass-a0a091miz0 | Acanthisitta chloris (rifleman). Hepatic triacylglycerol lipase | Acanthisitta chloris |
| 9pass-a0a093q3w3 | Manacus vitellinus (golden-collared manakin). Hepatic triacylglycerol lipase | Manacus vitellinus |
| 9tele-c1krj1 | Menidia estor (pike silverside). Triglyceride lipase | Menidia estor |
| 9tele-g7z082 | Sinocyclocheilus furcodorsalis (crossed-fork back golden-line fish). Hepatic lipase | Sinocyclocheilus furcodorsalis |
| 9tele-g7z091 | Channa maculata (blotched snakehead). Hepatic lipase | Channa maculata |
| 9tele-g7z092 | Cirrhinus molitorella (mud carp). Hepatic lipase | Cirrhinus molitorella |
| angan-a0a0e9wu50 | Anguilla anguilla (European freshwater eel) (Muraena anguilla). Uncharacterized protein | Anguilla anguilla |
| antcr-a0a094kdp3 | Antrostomus carolinensis (Chuck-will's-widow) (Caprimulgus carolinensis). Hepatic triacylglycerol lipase | Antrostomus carolinensis |
| atepa-1hlip | Ateles paniscus chamek hepatic lipase (LIPC) gene partial cds | Ateles paniscus chamek |
| balom-a0a1d8i1n8 | Balaenoptera omurai (Omura's baleen whale). Hepatic lipase | Balaenoptera omurai |
| bamth-a0a2p4stf2 | Bambusicola thoracicus (Chinese bamboo-partridge) (Perdix thoracica). Uncharacterized protein | Bambusicola thoracicus |
| bucrh-a0a091h6z1 | Buceros rhinoceros silvestris. Hepatic triacylglycerol lipase | Buceros rhinoceros silvestris |
| calan-a0a091hyb1 | Calypte anna (Anna's hummingbird) (Archilochus anna). Hepatic triacylglycerol lipase | Calypte anna |
| calja-f7bvl0 | Callithrix jacchus (White-tufted-ear marmoset). Uncharacterized protein | Callithrix jacchus |
| calsu-a0a226myh0 | Callipepla squamata (Scaled quail). Uncharacterized protein | Callipepla squamata |
| camfr-s9x4v6 | Camelus ferus (Wild bactrian camel) (Camelus bactrianus ferus). Hepatic triacylglycerol lipase | Camelus ferus |
| canfa-HTGL | Canis familiaris (Dog) hepatic triglyceride lipase precursor (fragment) | Canis lupus familiaris |
| caric-a0a091mde5 | Cariama cristata (Red-legged seriema). Hepatic triacylglycerol lipase | Cariama cristata |
| cereh-a0a212cuw4 | Cervus elaphus hippelaphus (European red deer). LIPC | Cervus elaphus hippelaphus |
| chavo-a0a0a0aid1 | Charadrius vociferus (Killdeer) (Aegialitis vocifera). Hepatic triacylglycerol lipase | Charadrius vociferus |
| chemy-m7bp12 | Chelonia mydas (Green sea-turtle) (Chelonia agassizi). Hepatic triacylglycerol lipase | Chelonia mydas |
| colvi-a0a226pis8 | Colinus virginianus (Northern bobwhite) (Tetrao virginianus). Uncharacterized protein | Colinus virginianus |
| corbr-a0a091e5i1 | Corvus brachyrhynchos (American crow). Hepatic triacylglycerol lipase | Corvus brachyrhynchos |
| cteid-g7z071 | Ctenopharyngodon idella (Grass carp) (Leuciscus idella). Hepatic lipase | Ctenopharyngodon idella |
| danre-f1qul2 | Danio rerio (Zebrafish) (Brachydanio rerio). Lipase, hepatic b | Danio rerio |
| delca-a0a1d8i1n2 | Delphinus capensis (Long-beaked common dolphin). Hepatic lipase | Delphinus capensis |
| delle-a0a1d8i1p2 | Delphinapterus leucas (Beluga whale). Hepatic lipase | Delphinapterus leucas |
| dicla-a0a172eak7 | Dicentrarchus labrax (European seabass) (Morone labrax). Hepatic lipase | Dicentrarchus labrax |
| drypu-a0a093g310 | Dryobates pubescens (Downy woodpecker) (Picoides pubescens). Hepatic triacylglycerol lipase | Dryobates pubescens |
| egrga-a0a091jjt2 | Egretta garzetta (Little egret). Hepatic triacylglycerol lipase | Egretta garzetta |
| escro-a0a2f0ay98 | Eschrichtius robustus (California gray whale) (Eschrichtius gibbosus). Hepatic triacylglycerol lipase | Eschrichtius robustus |
| eurhl-a0a093if69 | Eurypyga helias (Sunbittern). Hepatic triacylglycerol lipase | Eurypyga helias |
| fulga-a0a093ivv4 | Fulmarus glacialis (Northern fulmar). Hepatic triacylglycerol lipase | Fulmarus glacialis |
| halal-a0a091q0a4 | Haliaeetus albicilla (White-tailed sea-eagle). Hepatic triacylglycerol lipase | Haliaeetus albicilla |
| hypmo-g7z088 | Hypophthalmichthys molitrix (Silver carp) (Leuciscus molitrix). Hepatic lipase | Hypophthalmichthys molitrix |
| hypno-g7z093 | Hypophthalmichthys nobilis (Bighead carp) (Aristichthys nobilis). Hepatic lipase | Hypophthalmichthys nobilis |
| icttr-i3lwv8 | Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus tridecemlineatus). Lipase C, hepatic type | Ictidomys tridecemlineatus |
| larcr-k4jc39 | Larimichthys crocea (Large yellow croaker) (Pseudosciaena crocea). Hepatic lipase | Larimichthys crocea |
| lepdc-a0a091pl29 | Leptosomus discolor (Madagascar cuckoo roller) (Cuculus discolor). Hepatic triacylglycerol lipase | Leptosomus discolor |
| mernu-a0a091rmn1 | Merops nubicus (Northern carmine bee-eater). Hepatic triacylglycerol lipase | Merops nubicus |
| micsa-g7z070 | Micropterus salmoides (Largemouth bass) (Labrus salmoides). Hepatic lipase | Micropterus salmoides |
| myods-l5lrq1 | Myotis davidii (David's myotis). Hepatic triacylglycerol lipase | Myotis davidii |
| neole-a0a1a6fw10 | Neotoma lepida (Desert woodrat). Uncharacterized protein | Neotoma lepida |
| nesno-a0a091rs41 | Nestor notabilis (Kea). Hepatic triacylglycerol lipase | Nestor notabilis |
| nipni-a0a091vha8 | Nipponia nippon (Crested ibis) (Ibis nippon). Hepatic triacylglycerol lipase | Nipponia nippon |
| notfu-a0a1a8arg2 | Nothobranchius furzeri (Turquoise killifish). Lipase, hepatic a | Nothobranchius furzeri |
| oncmy-a0a060w3m9 | Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri). Uncharacterized protein | Oncorhynchus mykiss |
| opiho-a0a091v9q3 | Opisthocomus hoazin (Hoatzin) (Phasianus hoazin). Hepatic triacylglycerol lipase | Opisthocomus hoazin |
| oreni-g7z089 | Oreochromis niloticus (Nile tilapia) (Tilapia nilotica). Hepatic lipase | Oreochromis niloticus |
| ornan-f6uyd6 | Ornithorhynchus anatinus (Duckbill platypus). Uncharacterized protein | Ornithorhynchus anatinus |
| oryme-i1srw3 | Oryzias melastigma (Marine medaka). Hepatic lipase | Oryzias melastigma |
| pelcr-a0a091smy8 | Pelecanus crispus (Dalmatian pelican). Hepatic triacylglycerol lipase | Pelecanus crispus |
| phalp-a0a091ukq9 | Phaethon lepturus (White-tailed tropicbird). Hepatic triacylglycerol lipase | Phaethon lepturus |
| phorb-a0a091u1n6 | Phoenicopterus ruber ruber. Hepatic triacylglycerol lipase | Phoenicopterus ruber ruber |
| podcr-a0a094l8b9 | Podiceps cristatus (Great crested grebe). Hepatic triacylglycerol lipase | Podiceps cristatus |
| pteal-l5k133 | Pteropus alecto (Black flying fox). Hepatic triacylglycerol lipase | Pteropus alecto |
| pygad-a0a093ntw5 | Pygoscelis adeliae (Adelie penguin). Hepatic triacylglycerol lipase | Pygoscelis adeliae |
| schri-a0a2s0sra8 | Schizothorax richardsonii (Snowtrout) (Cyprinus richardsonii). Hepatic lipase | Schizothorax richardsonii |
| solso-s5tm72 | Solea solea (Common sole). Hepatic lipase | Solea solea |
| strca-a0a093i0e7 | Struthio camelus australis. Hepatic triacylglycerol lipase | Struthio camelus australis |
| tauer-a0a093c715 | Tauraco erythrolophus (Red-crested turaco). Hepatic triacylglycerol lipase | Tauraco erythrolophus |
| tingu-a0a099z7m5 | Tinamus guttatus (White-throated tinamou). Hepatic triacylglycerol lipase | Tinamus guttatus |
| tytal-a0a093g200 | Tyto alba (Barn owl). Hepatic triacylglycerol lipase | Tyto alba |
| Substrate | Chemical Nomenclature | Proteins |
|---|---|---|
| 1-Stearoyl-2-arachidonylphosphatidylcholine | [2-[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoyl]oxy-3-octadecanoyloxypropyl] 2-(trimethylazaniumyl)ethyl phosphate | human-LCAT human-LIPC |
| 1-palmitoyl-2-linoleoylphosphatidylcholine | [3-hexadecanoyloxy-2-[(9Z,12Z)-octadeca-9,12-dienoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate | arath-PLA12 human-LCAT human-LIPC human-LIPG |
| Diheptadecanoylphosphatidylcholine | 2,3-di(heptadecanoyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate | |
| Dipalmitoylphosphatidylglycerol | [3-[2,3-dihydroxypropoxy(hydroxy)phosphoryl]oxy-2-hexadecanoyloxypropyl] hexadecanoate | legpn-i7i328 |
| Egg-Lecithin | human-PNLIPRP2 talth-f6lqk7 nech7-c7yuz1 cavpo-2plrp canan-lipasA rhimi-lipas rhidl-lipas | |
| Heptadecanoylphosphatidylcholine | [(2R)-3-heptadecanoyloxy-2-hydroxypropyl] 2-(trimethylazaniumyl)ethyl phosphate | pseae-PA2927 legpn-i7i328 |
| Triolein | 2,3-bis[[(Z)-octadec-9-enoyl]oxy]propyl (Z)-octadec-9-enoate | pseae-llipa mouse-Ces2c human-CES2 human-PNLIP |
| Tripentadecanoin | 2,3-di(pentadecanoyloxy)propyl pentadecanoate |
| Inhibitor | Chemical Nomenclature | Proteins |
|---|---|---|
| Ebelactone-B | (3S,4S)-3-ethyl-4-[(E,2S,6R,8S,9R,10R)-9-hydroxy-4,6,8,10-tetramethyl-7-oxododec-4-en-2-yl]oxetan-2-one |
References (2)
| Title : Vertebrate hepatic lipase genes and proteins: a review supported by bioinformatic studies - Holmes_2011_Open.Access.Bioinformatics_2011_85 |
| Author(s) : Holmes RS , Vandeberg JL , Cox LA |
| Ref : Open Access Bioinformatics , 2011 :85 , 2011 |
| Abstract : |
| PubMedSearch : Holmes_2011_Open.Access.Bioinformatics_2011_85 |
| PubMedID: 22408368 |
| Title : Human hepatic lipase mutations and polymorphisms - Hegele_1992_Hum.Mutat_1_320 |
| Author(s) : Hegele RA , Tu L , Connelly PW |
| Ref : Hum Mutat , 1 :320 , 1992 |
| Abstract : |
| PubMedSearch : Hegele_1992_Hum.Mutat_1_320 |
| PubMedID: 1301939 |