Gene_locus Report for: schpo-yk68

only central part Pfam A DUF726 175 519

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Fungi: N E > Dikarya: N E > Ascomycota: N E > Taphrinomycotina: N E > Schizosaccharomycetes: N E > Schizosaccharomycetales: N E > Schizosaccharomycetaceae: N E > Schizosaccharomyces: N E > Schizosaccharomyces pombe: N E

ABHD11-Acetyl_transferase : schpo-C22H12.03Schizosaccharomyces pombe (Fission yeast) hypothetical 30.8 kda protein c22h12.03 in chromosome i.
ABHD13-BEM46 : schpo-be46Schizosaccharomyces pombe (Fission yeast) protein bem46.
Acidic_Lipase : schpo-SPBC14C8.15Schizosaccharomyces pombe (Fission yeast) hypothetical 52.7 kda protein, schpo-SPBC16A3.12CSchizosaccharomyces pombe (Fission yeast) putative triglyceride lipase-cholesterol esterase (EC 3.1.1.-), schpo-SPCC1672.09Schizosaccharomyces pombe (Fission yeast) triglyceride lipase-cholesterol esterase.
AlphaBeta_hydrolase : schpo-C57A10.08CSchizosaccharomyces pombe (Fission yeast) hypothetical 41.8 kda protein c57a10.08c in chromosome i, schpo-ydw6Schizosaccharomyces pombe (Fission yeast) Uncharacterized protein C23C11.06c, schpo-ykv6Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). Uncharacterized protein C959.06c.
Arb2_domain : schpo-clr3 Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). Cryptic loci regulator 3.
Carboxypeptidase_S10 : schpo-KEX1Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) putative serine carboxypeptidase c16g5.09 precursor (EC 3.4.16.-), schpo-PCY1Schizosaccharomyces pombe (Fission yeast) carboxypeptidase y precursor (EC 3.4.16.5) (carboxypeptidase yscy), schpo-sxa2Schizosaccharomyces pombe sxa2 protease.
CGI-58_ABHD5_ABHD4 : schpo-ye63Schizosaccharomyces pombe (Fission yeast) hypothetical 48.7 kda protein c6g10.03c in chromosome i.
Dienelactone_hydrolase : schpo-SPAC977.15Schizosaccharomyces pombe (Fission yeast) hypothetical protein, schpo-yb4eSchizosaccharomyces pombe (Fission yeast) hypothetical protein c30d10.14 in chromosome II.
DPP4N_Peptidase_S9 : schpo-C2E11.08Schizosaccharomyces pombe (Fission yeast) putative dipeptidyl aminopeptidase c2e11.08 (EC 3.4.14.-), schpo-C14C4.15CSchizosaccharomyces pombe (Fission yeast) dipeptidyl aminopeptidase c14c4.15c (EC 3.4.14.-) (fragment).
Duf_676 : schpo-ye7aSchizosaccharomyces pombe (Fission yeast) hypothetical protein c4a8.10 in chromosome i.
Duf_726 : schpo-yeldSchizosaccharomyces pombe (Fission yeast) Uncharacterized membrane protein C6F6.13c.
FSH1 : schpo-dyrSchizosaccharomyces pombe (Fission yeast) dihydrofolate reductase (EC 1.5.1.3), schpo-C22A12.06CSchizosaccharomyces pombe (Fission yeast) similar to s. pombe dihydrofolate reductase dfr1p.
Fungal_carboxylesterase_lipase : schpo-SPCC417.12Schizosaccharomyces pombe (Fission yeast) hypothetical 59.2 kda protein c417.12 in chromosome III.
Fusarinine_C_esterase_sidJ : schpo-q9c0y8Schizosaccharomyces pombe (Fission yeast). spapb24d3.06c protein.
Homoserine_transacetylase : schpo-met2Schizosaccharomyces pombe (Fission yeast) Homoserine O-acetyltransferase, schpo-yblhSchizosaccharomyces pombe (Fission yeast) hypothetical 56.4 kda protein c106.17c in chromosome II.
Hormone-sensitive_lipase_like : schpo-este1Schizosaccharomyces pombe chromosome I cosmid c1039,gene SPAC1039.03, schpo-SPAC4A8.06CSchizosaccharomyces pombe (Fission yeast) hypothetical protein, schpo-SPAPB1A11.02Schizosaccharomyces pombe (Fission yeast) putative esterase-lipase.
Lipase_3 : schpo-C23C4.16CSchizosaccharomyces pombe (Fission yeast) hypothetical 47.9 kda protein c23c4.16c in chromosome I (autophagy-related protein 15).
LYsophospholipase_carboxylesterase : schpo-APTH1Schizosaccharomyces pombe lysophoshpholipase YFQ4 APTH1 on chromosome I cosmid c8E11, schpo-ye88Schizosaccharomyces pombe (Fission yeast) hypothetical 27.3 kda protein c9g1.08c in chromosome i.
Monoglyceridelipase_lysophospholip : schpo-SPCC5E4.05CSchizosaccharomyces pombe (Fission yeast) hypothetical 41.6 kda protein.
PAF-Acetylhydrolase : schpo-PLG7Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) SPBC106.11C PLG7 hypothetical protein.
Palmitoyl-protein_thioesterase : schpo-SPBC530.12CSchizosaccharomyces pombe (Fission yeast) palmitoyl-protein thioesterase precursor.
PC-sterol_acyltransferase : schpo-pdatSchizosaccharomyces pombe (Fission yeast) (pdat).
PGAP1 : schpo-BST1Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) putative negative regulator of vesicle formation.
PPase_methylesterase_euk : schpo-ppme1Schizosaccharomyces pombe (Fission yeast) putative phosphatase methylesterase 1 (EC 3.1.1.-) (pme-1).
Prolyl_oligopeptidase_S9 : schpo-SPBC1711.12Schizosaccharomyces pombe (Fission yeast) putative dipeptidyl peptidase, possibly secreted.
Steryl_acetyl_hydrolase : schpo-SPBPB2B2.02Schizosaccharomyces pombe (Fission yeast) and (strain ATCC 38366 / 972) Putative steryl acetyl hydrolase mug180 Meiotically up-regulated gene 180 protein

Title: ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe
Matsuyama A, Arai R, Yashiroda Y, Shirai A, Kamata A, Sekido S, Kobayashi Y, Hashimoto A, Hamamoto M and Yoshida M <2 more author(s)> Matsuyama A, Arai R, Yashiroda Y, Shirai A, Kamata A, Sekido S, Kobayashi Y, Hashimoto A, Hamamoto M, Hiraoka Y, Horinouchi S, Yoshida M (- 2)
Ref: Nat Biotechnol, 24:841, 2006 : PubMed
Abstract


ESTHER: Matsuyama_2006_Nat.Biotechnol_24_841
PubMedSearch: Matsuyama 2006 Nat.Biotechnol 24 841
PubMedID: 16823372
Gene_locus related to this paper: schpo-APTH1, schpo-KEX1, schpo-PLG7, schpo-SPAC4A8.06C, schpo-SPBC14C8.15, schpo-SPBPB2B2.02, schpo-SPCC5E4.05C, schpo-SPCC417.12, schpo-yeld, schpo-yk68, schpo-clr3

Abstract

Cloning of the entire set of an organism's protein-coding open reading frames (ORFs), or 'ORFeome', is a means of connecting the genome to downstream 'omics' applications. Here we report a proteome-scale study of the fission yeast Schizosaccharomyces pombe based on cloning of the ORFeome. Taking advantage of a recombination-based cloning system, we obtained 4,910 ORFs in a form that is readily usable in various analyses. First, we evaluated ORF prediction in the fission yeast genome project by expressing each ORF tagged at the 3' terminus. Next, we determined the localization of 4,431 proteins, corresponding to approximately 90% of the fission yeast proteome, by tagging each ORF with the yellow fluorescent protein. Furthermore, using leptomycin B, an inhibitor of the nuclear export protein Crm1, we identified 285 proteins whose localization is regulated by Crm1.



        

Title: The genome sequence of Schizosaccharomyces pombe
Wood V, Gwilliam R, Rajandream MA, Lyne M, Lyne R, Stewart A, Sgouros J, Peat N, Hayles J and Nurse P <124 more author(s)> Wood V, Gwilliam R, Rajandream MA, Lyne M, Lyne R, Stewart A, Sgouros J, Peat N, Hayles J, Baker S, Basham D, Bowman S, Brooks K, Brown D, Brown S, Chillingworth T, Churcher C, Collins M, Connor R, Cronin A, Davis P, Feltwell T, Fraser A, Gentles S, Goble A, Hamlin N, Harris D, Hidalgo J, Hodgson G, Holroyd S, Hornsby T, Howarth S, Huckle EJ, Hunt S, Jagels K, James K, Jones L, Jones M, Leather S, McDonald S, McLean J, Mooney P, Moule S, Mungall K, Murphy L, Niblett D, Odell C, Oliver K, O'Neil S, Pearson D, Quail MA, Rabbinowitsch E, Rutherford K, Rutter S, Saunders D, Seeger K, Sharp S, Skelton J, Simmonds M, Squares R, Squares S, Stevens K, Taylor K, Taylor RG, Tivey A, Walsh S, Warren T, Whitehead S, Woodward J, Volckaert G, Aert R, Robben J, Grymonprez B, Weltjens I, Vanstreels E, Rieger M, Schafer M, Muller-Auer S, Gabel C, Fuchs M, Dusterhoft A, Fritzc C, Holzer E, Moestl D, Hilbert H, Borzym K, Langer I, Beck A, Lehrach H, Reinhardt R, Pohl TM, Eger P, Zimmermann W, Wedler H, Wambutt R, Purnelle B, Goffeau A, Cadieu E, Dreano S, Gloux S, Lelaure V, Mottier S, Galibert F, Aves SJ, Xiang Z, Hunt C, Moore K, Hurst SM, Lucas M, Rochet M, Gaillardin C, Tallada VA, Garzon A, Thode G, Daga RR, Cruzado L, Jimenez J, Sanchez M, del Rey F, Benito J, Dominguez A, Revuelta JL, Moreno S, Armstrong J, Forsburg SL, Cerutti L, Lowe T, McCombie WR, Paulsen I, Potashkin J, Shpakovski GV, Ussery D, Barrell BG, Nurse P (- 124)
Ref: Nature, 415:871, 2002 : PubMed
Abstract


ESTHER: Wood_2002_Nature_415_871
PubMedSearch: Wood 2002 Nature 415 871
PubMedID: 11859360
Gene_locus related to this paper: schpo-APTH1, schpo-be46, schpo-BST1, schpo-C2E11.08, schpo-C14C4.15C, schpo-C22H12.03, schpo-C23C4.16C, schpo-C57A10.08C, schpo-dyr, schpo-este1, schpo-KEX1, schpo-PCY1, schpo-pdat, schpo-PLG7, schpo-ppme1, schpo-q9c0y8, schpo-SPAC4A8.06C, schpo-C22A12.06C, schpo-SPAC977.15, schpo-SPAPB1A11.02, schpo-SPBC14C8.15, schpo-SPBC530.12C, schpo-SPBC1711.12, schpo-SPBPB2B2.02, schpo-SPCC5E4.05C, schpo-SPCC417.12, schpo-SPCC1672.09, schpo-yb4e, schpo-yblh, schpo-ydw6, schpo-ye7a, schpo-ye63, schpo-ye88, schpo-yeld, schpo-yk68, schpo-clr3, schpo-ykv6

Abstract

We have sequenced and annotated the genome of fission yeast (Schizosaccharomyces pombe), which contains the smallest number of protein-coding genes yet recorded for a eukaryote: 4,824. The centromeres are between 35 and 110 kilobases (kb) and contain related repeats including a highly conserved 1.8-kb element. Regions upstream of genes are longer than in budding yeast (Saccharomyces cerevisiae), possibly reflecting more-extended control regions. Some 43% of the genes contain introns, of which there are 4,730. Fifty genes have significant similarity with human disease genes; half of these are cancer related. We identify highly conserved genes important for eukaryotic cell organization including those required for the cytoskeleton, compartmentation, cell-cycle control, proteolysis, protein phosphorylation and RNA splicing. These genes may have originated with the appearance of eukaryotic life. Few similarly conserved genes that are important for multicellular organization were identified, suggesting that the transition from prokaryotes to eukaryotes required more new genes than did the transition from unicellular to multicellular organization.