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  3. Sigma1R ligand

Sigma1R ligand

General

Ligand of Sigma1 receptor. Not an alpha/beta hydrolase target but can be used as a building block for larger inhibitors of enzymes of the family designed as multitarget compounds
Inhibitor Main targeted enzyme families Type Structure
CHEMBL4595876 ACHE Multitarget Pyridine Sigma1R ligand Cyanide Alkyne
Contilistat Multitarget Histamine-Receptor3-H3-Antagonist Monoamine-oxidase-inhibitor Piperidine Indole HDAC inhibitor Alkyne Sulfur Compound Sigma1R ligand
Sigma1R-ACHE-6a ACHE Multitarget 5-HT-receptor-ligand Piperidine Sigma1R ligand Indole Derivative of Donepezil
Sigma1R-ACHE-6b ACHE Multitarget 5-HT-receptor-ligand Piperidine Sigma1R ligand Indole Derivative of Donepezil