1. Home
  2. Type Substrate
  3. Pyridine

Pyridine

Pyridine is a basic heterocyclic organic compound with the chemical formula C5H5N. It is structurally related to benzene, with one methine group (=CH-) replaced by a nitrogen atom. Pyridine is not abundant in nature, except for the leaves and roots of belladonna (Atropa belladonna) and in marshmallow (Althaea officinalis, Guimauve officinale). Pyridine derivatives, however, are often part of biomolecules such as alkaloids. Building block for many inhibitors of enzymes
Substrate Main targeted enzyme families Type Structure
Arecoline Carb_B_Chordata Muscarinic agonist Nicotinic agonist Pyridine Natural
FPD5 Pyridine Pyrazole
TXH1033 ACHE Piperidine Pyridine Pro-Drug Carboxamide
BDPN2-CES Carb_B_Chordata Fluorescent Probe BODIPY-derivative Boron compound Pyridine
Unecritinib Carb_B_Chordata Not AlphaBeta Hydrolase target Pro-Drug Drug Piperidine Pyrazole Pyridine
N-benzyl-picolinamide Hormone-sensitive_lipase_like Pyridine Carboxamide
Clodinafop-propargyl Plant_carboxylesterase Herbicide Pyridine Propionate Alkyne
Fluazifop-butyl Carb_B_Chordata Herbicide Trifluoro Pyridine
Abiraterone-acetate Arylacetamide_deacetylase Pro-Drug Drug Pyridine Not AlphaBeta Hydrolase target Phenanthrene
Chlorantraniliprole Insecticide Carbamate Pyridine Carboxamide Pyrazole
Streptonigrin-derivative 6_AlphaBeta_hydrolase Pyridine Quinoline
Vicagrel Arylacetamide_deacetylase Carb_B_Chordata Not AlphaBeta Hydrolase target Drug Pyridine Acetate Antiplatelet
2-oxo-clopidogrel Carb_B_Chordata Not AlphaBeta Hydrolase target Drug Pro-Drug Pyridine Acetate Antiplatelet
4-MOMMP Carb_B_Chordata Pyridine
6-Hydroxypseudooxynicotine Duf_1100-S Derivative of Nicotine Pyridine
Dabigatran-etexilate Carb_B_Chordata Pro-Drug Not AlphaBeta Hydrolase target Drug Pyridine Propionate Benzimidazole
Clopidogrel Carb_B_Chordata Not AlphaBeta Hydrolase target Drug Pyridine Antiplatelet
DDPDPDC Aryl ester Pyridine