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Insecticide

Insecticides are substances used to kill insects. The main insecticides interacting with alpha\/beta hydrolases are carbamates and organophosphates that inhibit acetylcholinesterases or carboxylesterases of insects. Few neonicotinoids or pyrthrinoids target alpha\/beta hydrolases
Substrate Main targeted enzyme families Type Structure
Emamectin Carb_B_Arthropoda Anthelmintic Insecticide Macrocycle
Abamectin-B1a Cholinesterase-like Anthelmintic Insecticide Macrocycle
Indoxacarb Carb_B_Arthropoda Insecticide Carboxamide Carbamate Trifluoro Not AlphaBeta Hydrolase target
Cypermethrin Carb_B_Arthropoda LYsophospholipase_carboxylesterase Carb_B_Chordata 6_AlphaBeta_hydrolase Haloperoxidase Pyrethroid Insecticide Phenoxyphenyl Cyclopropyl Not AlphaBeta Hydrolase target Cyanide Organochlorine
Cypermethrine-analog-fluo-CpdII Carb_B_Arthropoda Carb_B_Chordata Pyrethroid Insecticide Naphthalen Cyclopropyl Not AlphaBeta Hydrolase target Cyanide Organochlorine
Fenvalerate-analog-fluo-CpdII Carb_B_Arthropoda Insecticide Naphthalen Not AlphaBeta Hydrolase target Cyanide Organochlorine
Cypermethrine-analog-acid-CpdI Carb_B_Arthropoda Carb_B_Chordata Insecticide Naphthalen Cyclopropyl Not AlphaBeta Hydrolase target Cyanide
Fenvalerate-analog-acid-CpdI Carb_B_Arthropoda Insecticide Naphthalen Not AlphaBeta Hydrolase target Cyanide
Gossypol Carb_B_Arthropoda Natural Insecticide Polyphenol
Chlorantraniliprole Insecticide Carbamate Pyridine Carboxamide Pyrazole Organochlorine
1,3,4,6-Tetrachloro-1,4-cyclohexadiene Haloalkane_dehalogenase-HLD1 Haloalkane_dehalogenase-HLD2 Insecticide Organochlorine
Lindane Haloalkane_dehalogenase-HLD1 Haloalkane_dehalogenase-HLD2 Insecticide Organochlorine
trans-Bifenthrin HNLyase_Bact Carb_B_Arthropoda Pyrethroid Insecticide Trifluoro Not AlphaBeta Hydrolase target Carbamate Cyclopropyl
Fenpropathrin Carb_B_Arthropoda Cholinesterase-like Pyrethroid Insecticide Acaricide Cyanide Not AlphaBeta Hydrolase target Phenoxyphenyl Cyclopropyl
lambda-Cyhalothrin Carb_B_Arthropoda CarbLipBact_1 6_AlphaBeta_hydrolase HNLyase_Bact Pyrethroid Insecticide Phenoxyphenyl Cyanide Cyclopropyl
Deltamethrin Carboxylesterase Carb_B_Chordata Carb_B_Arthropoda Carb_B_Bacteria 6_AlphaBeta_hydrolase HNLyase_Bact Pyrethroid Insecticide Phenoxyphenyl Cyanide Cyclopropyl
Fenobucarb ACHE Hormone-sensitive_lipase_like Insecticide Carbamate
Aldicarb ACHE Insecticide Carbamate Sulfur Compound
Chlorpyrifos Est9X Duf_3089 Trichloro Insecticide Organophosphate Sulfur Compound Organothiophosphate OPIDN-OP Organochlorine
Chlorpyrifos-oxon Arylacetamide_deacetylase Hormone-sensitive_lipase_like Trichloro Insecticide Organophosphate Organochlorine
Malathion Insecticide Acaricide Organophosphate Sulfur Compound Organothiophosphate
Paraoxon BCHE Dienelactone_hydrolase Organophosphate Insecticide Derivative of Paraoxon pNP
Permethrin Carboxylesterase Carb_B_Chordata Carb_B_Arthropoda Carb_B_Bacteria Pyrethroid Insecticide Drug Not AlphaBeta Hydrolase target Phenoxyphenyl Cyclopropyl
Emamectin Carb_B_Arthropoda Anthelmintic Insecticide Macrocycle
Abamectin-B1a Cholinesterase-like Anthelmintic Insecticide Macrocycle
Indoxacarb Carb_B_Arthropoda Insecticide Carboxamide Carbamate Trifluoro Not AlphaBeta Hydrolase target
Cypermethrin Carb_B_Arthropoda LYsophospholipase_carboxylesterase Carb_B_Chordata 6_AlphaBeta_hydrolase Haloperoxidase Pyrethroid Insecticide Phenoxyphenyl Cyclopropyl Not AlphaBeta Hydrolase target Cyanide Organochlorine
Cypermethrine-analog-fluo-CpdII Carb_B_Arthropoda Carb_B_Chordata Pyrethroid Insecticide Naphthalen Cyclopropyl Not AlphaBeta Hydrolase target Cyanide Organochlorine
Fenvalerate-analog-fluo-CpdII Carb_B_Arthropoda Insecticide Naphthalen Not AlphaBeta Hydrolase target Cyanide Organochlorine
Cypermethrine-analog-acid-CpdI Carb_B_Arthropoda Carb_B_Chordata Insecticide Naphthalen Cyclopropyl Not AlphaBeta Hydrolase target Cyanide
Fenvalerate-analog-acid-CpdI Carb_B_Arthropoda Insecticide Naphthalen Not AlphaBeta Hydrolase target Cyanide
Gossypol Carb_B_Arthropoda Natural Insecticide Polyphenol
Chlorantraniliprole Insecticide Carbamate Pyridine Carboxamide Pyrazole Organochlorine
1,3,4,6-Tetrachloro-1,4-cyclohexadiene Haloalkane_dehalogenase-HLD1 Haloalkane_dehalogenase-HLD2 Insecticide Organochlorine
Lindane Haloalkane_dehalogenase-HLD1 Haloalkane_dehalogenase-HLD2 Insecticide Organochlorine
trans-Bifenthrin HNLyase_Bact Carb_B_Arthropoda Pyrethroid Insecticide Trifluoro Not AlphaBeta Hydrolase target Carbamate Cyclopropyl
Fenpropathrin Carb_B_Arthropoda Cholinesterase-like Pyrethroid Insecticide Acaricide Cyanide Not AlphaBeta Hydrolase target Phenoxyphenyl Cyclopropyl
lambda-Cyhalothrin Carb_B_Arthropoda CarbLipBact_1 6_AlphaBeta_hydrolase HNLyase_Bact Pyrethroid Insecticide Phenoxyphenyl Cyanide Cyclopropyl
Deltamethrin Carboxylesterase Carb_B_Chordata Carb_B_Arthropoda Carb_B_Bacteria 6_AlphaBeta_hydrolase HNLyase_Bact Pyrethroid Insecticide Phenoxyphenyl Cyanide Cyclopropyl
Fenobucarb ACHE Hormone-sensitive_lipase_like Insecticide Carbamate
Aldicarb ACHE Insecticide Carbamate Sulfur Compound
Chlorpyrifos Est9X Duf_3089 Trichloro Insecticide Organophosphate Sulfur Compound Organothiophosphate OPIDN-OP Organochlorine
Chlorpyrifos-oxon Arylacetamide_deacetylase Hormone-sensitive_lipase_like Trichloro Insecticide Organophosphate Organochlorine
Malathion Insecticide Acaricide Organophosphate Sulfur Compound Organothiophosphate
Paraoxon BCHE Dienelactone_hydrolase Organophosphate Insecticide Derivative of Paraoxon pNP
Permethrin Carboxylesterase Carb_B_Chordata Carb_B_Arthropoda Carb_B_Bacteria Pyrethroid Insecticide Drug Not AlphaBeta Hydrolase target Phenoxyphenyl Cyclopropyl
Emamectin Carb_B_Arthropoda Anthelmintic Insecticide Macrocycle
Abamectin-B1a Cholinesterase-like Anthelmintic Insecticide Macrocycle
Indoxacarb Carb_B_Arthropoda Insecticide Carboxamide Carbamate Trifluoro Not AlphaBeta Hydrolase target
Cypermethrin Carb_B_Arthropoda LYsophospholipase_carboxylesterase Carb_B_Chordata 6_AlphaBeta_hydrolase Haloperoxidase Pyrethroid Insecticide Phenoxyphenyl Cyclopropyl Not AlphaBeta Hydrolase target Cyanide Organochlorine
Cypermethrine-analog-fluo-CpdII Carb_B_Arthropoda Carb_B_Chordata Pyrethroid Insecticide Naphthalen Cyclopropyl Not AlphaBeta Hydrolase target Cyanide Organochlorine
Fenvalerate-analog-fluo-CpdII Carb_B_Arthropoda Insecticide Naphthalen Not AlphaBeta Hydrolase target Cyanide Organochlorine
Cypermethrine-analog-acid-CpdI Carb_B_Arthropoda Carb_B_Chordata Insecticide Naphthalen Cyclopropyl Not AlphaBeta Hydrolase target Cyanide
Fenvalerate-analog-acid-CpdI Carb_B_Arthropoda Insecticide Naphthalen Not AlphaBeta Hydrolase target Cyanide
Gossypol Carb_B_Arthropoda Natural Insecticide Polyphenol
Chlorantraniliprole Insecticide Carbamate Pyridine Carboxamide Pyrazole Organochlorine
1,3,4,6-Tetrachloro-1,4-cyclohexadiene Haloalkane_dehalogenase-HLD1 Haloalkane_dehalogenase-HLD2 Insecticide Organochlorine
Lindane Haloalkane_dehalogenase-HLD1 Haloalkane_dehalogenase-HLD2 Insecticide Organochlorine
trans-Bifenthrin HNLyase_Bact Carb_B_Arthropoda Pyrethroid Insecticide Trifluoro Not AlphaBeta Hydrolase target Carbamate Cyclopropyl
Fenpropathrin Carb_B_Arthropoda Cholinesterase-like Pyrethroid Insecticide Acaricide Cyanide Not AlphaBeta Hydrolase target Phenoxyphenyl Cyclopropyl
lambda-Cyhalothrin Carb_B_Arthropoda CarbLipBact_1 6_AlphaBeta_hydrolase HNLyase_Bact Pyrethroid Insecticide Phenoxyphenyl Cyanide Cyclopropyl
Deltamethrin Carboxylesterase Carb_B_Chordata Carb_B_Arthropoda Carb_B_Bacteria 6_AlphaBeta_hydrolase HNLyase_Bact Pyrethroid Insecticide Phenoxyphenyl Cyanide Cyclopropyl
Fenobucarb ACHE Hormone-sensitive_lipase_like Insecticide Carbamate
Aldicarb ACHE Insecticide Carbamate Sulfur Compound
Chlorpyrifos Est9X Duf_3089 Trichloro Insecticide Organophosphate Sulfur Compound Organothiophosphate OPIDN-OP Organochlorine
Chlorpyrifos-oxon Arylacetamide_deacetylase Hormone-sensitive_lipase_like Trichloro Insecticide Organophosphate Organochlorine
Malathion Insecticide Acaricide Organophosphate Sulfur Compound Organothiophosphate
Paraoxon BCHE Dienelactone_hydrolase Organophosphate Insecticide Derivative of Paraoxon pNP
Permethrin Carboxylesterase Carb_B_Chordata Carb_B_Arthropoda Carb_B_Bacteria Pyrethroid Insecticide Drug Not AlphaBeta Hydrolase target Phenoxyphenyl Cyclopropyl