Extracted from Hormone sensitive lipases. Proteins in this entry belong to the 'GDXG' family of lypolytic enzymes and are also known as Aes proteins. They have esterase activity against short chain (up to 8 carbon atoms) fatty esters and are able to hydrolyse triacetin and tributyrin but not triolein or cholesterol oleate. These proteins are involved in the downregulation of the transcriptional activator of the maltose regulon, MalT, in E. coli. The Aes protein and the monomeric alpha-galactosidase from Escherichia coli form a non-covalent complex. HAMAP: MF_01958
Interpro : IPR023508 Acetyl esterase
PIRSF : No PIRSF
Pdoc : No Pdoc
Pfam : No Pfam
Prints : No Print
EC Number : No EC Number
Structures (3)
Genes Proteins in Acetyl_esterase family (61)
No fragment of genes
Structures in Acetyl_esterase family (3)No substrate
Inhibitors in Acetyl_esterase family (3)
Title : Structural and mutational analyses of Aes, an inhibitor of MalT in Escherichia coli - Schiefner_2014_Proteins_82_268 |
Author(s) : Schiefner A , Gerber K , Brosig A , Boos W |
Ref : Proteins , 82 :268 , 2014 |
Abstract : Schiefner_2014_Proteins_82_268 |
ESTHER : Schiefner_2014_Proteins_82_268 |
PubMedSearch : Schiefner_2014_Proteins_82_268 |
PubMedID: 23934774 |
Gene_locus related to this paper: ecoli-Aes |
Title : The Aes protein and the monomeric alpha-galactosidase from Escherichia coli form a non-covalent complex. Implications for the regulation of carbohydrate metabolism - Mandrich_2002_J.Biol.Chem_277_48241 |
Author(s) : Mandrich L , Caputo E , Martin BM , Rossi M , Manco G |
Ref : Journal of Biological Chemistry , 277 :48241 , 2002 |
Abstract : Mandrich_2002_J.Biol.Chem_277_48241 |
ESTHER : Mandrich_2002_J.Biol.Chem_277_48241 |
PubMedSearch : Mandrich_2002_J.Biol.Chem_277_48241 |
PubMedID: 12374803 |
Gene_locus related to this paper: ecoli-Aes |
Title : The Aes protein directly controls the activity of MalT, the central transcriptional activator of the Escherichia coli maltose regulon - Joly_2002_J.Biol.Chem_277_16606 |
Author(s) : Joly N , Danot O , Schlegel A , Boos W , Richet E |
Ref : Journal of Biological Chemistry , 277 :16606 , 2002 |
Abstract : Joly_2002_J.Biol.Chem_277_16606 |
ESTHER : Joly_2002_J.Biol.Chem_277_16606 |
PubMedSearch : Joly_2002_J.Biol.Chem_277_16606 |
PubMedID: 11867639 |
Gene_locus related to this paper: ecoli-Aes |