Acetyl_esterase
Relationship
Comment
Extracted from Hormone sensitive lipases. Proteins in this entry belong to the 'GDXG' family of lypolytic enzymes and are also known as Aes proteins. They have esterase activity against short chain (up to 8 carbon atoms) fatty esters and are able to hydrolyse triacetin and tributyrin but not triolein or cholesterol oleate. These proteins are involved in the downregulation of the transcriptional activator of the maltose regulon, MalT, in E. coli. The Aes protein and the monomeric alpha-galactosidase from Escherichia coli form a non-covalent complex. HAMAP: MF_01958
Database
Interpro : IPR023508 Acetyl esterase
PIRSF : No PIRSF
Pdoc : No Pdoc
Pfam : No Pfam
Prints : No Print
EC Number : No EC Number
Sequences
| Peptide in | Fasta |
| Nucleotide in | Fasta |
| Alignment with Multalin | Text only |
| Seed alignment with MAFFT | No colour / coloured with Mview |
| Alignment with MAFFT | No colour / coloured with Mview |
| Dendrogram | The dnd file |
| Gene_locus | Name | Species |
|---|---|---|
| 9entr-a0a0j1lkz5 | Citrobacter sp. Acetyl esterase \; EC=3.1.1.- \; | Citrobacter sp. |
| 9entr-a0a0j1n412 | Citrobacter sp.\; Citrobacter freundii\; environmental samples uncultured Citrobacter sp. Acetyl esterase \; EC=3.1.1.- \; | Citrobacter sp. |
| 9entr-a0a0l0h238 | Trabulsiella odontotermitis Acetyl esterase \; EC=3.1.1.- \; | Trabulsiella odontotermitis |
| 9entr-a0a2k9pbr3 | Citrobacter freundii complex sp. \; Citrobacter amalonaticus\; Acetyl esterase \; EC=3.1.1.- \; | Citrobacter freundii complex sp. CFNIH2 |
| 9entr-a0a2z3xdl3 | Citrobacter sp.\; Citrobacter sp.\; Citrobacter werkmanii\; Citrobacter freundii\; Citrobacter cronae\; Acetyl esterase \; EC=3.1.1.- \; | Citrobacter sp. |
| 9entr-a0a381c7i6 | Buttiauxella agrestis Acetyl esterase \; EC=3.1.1.- \; | Buttiauxella agrestis |
| 9entr-a0a3e2kwl0 | Citrobacter gillenii\; Citrobacter sp.\; Citrobacter freundii\; Citrobacter sp. Acetyl esterase \; EC=3.1.1.- \; | Citrobacter gillenii |
| 9entr-a0a3q8d961 | Citrobacter sp. (Salmonella choleraesuis)\; Citrobacter amalonaticus\; Salmonella enterica Acetyl esterase \; EC=3.1.1.- \; | Citrobacter sp. |
| 9entr-a0a4p6wgm2 | Citrobacter arsenatis Acetyl esterase \; EC=3.1.1.- \; | Citrobacter arsenatis |
| 9entr-a0a4u6lhg0 | Citrobacter sp. Acetyl esterase \; EC=3.1.1.- \; | Citrobacter sp. |
| 9entr-a0a4v1bpt9 | Citrobacter tructae Acetyl esterase \; EC=3.1.1.- \; | Citrobacter tructae |
| 9entr-a0a5b0kg68 | Pseudocitrobacter sp. Acetyl esterase \; EC=3.1.1.- \; | Pseudocitrobacter sp. |
| 9entr-a0a658p3a9 | Citrobacter sp.\; Citrobacter portucalensis\; Citrobacter freundii Acetyl esterase \; EC=3.1.1.- \; | Citrobacter sp. |
| 9entr-a0a6l5e805 | Citrobacter telavivensis Acetyl esterase \; EC=3.1.1.- \; | Citrobacter telavivensis |
| 9entr-a0a7l6xny0 | Citrobacter sp. Acetyl esterase \; EC=3.1.1.- \; | Citrobacter sp. |
| 9entr-a0a806x514 | Pluralibacter [Enterobacter] lignolyticus (strain SCF1) Acetyl esterase \; EC=3.1.1.- \; | Enterobacter lignolyticus |
| 9entr-a0a8h9ntq7 | Citrobacter farmeri Acetyl esterase \; EC=3.1.1.- \; | Citrobacter farmeri |
| 9entr-a0a923ip92 | Citrobacter pasteurii Acetyl esterase \; EC=3.1.1.- \; | Citrobacter pasteurii |
| 9entr-d4bcx2 | Citrobacter youngae ATCC 29220 Acetyl esterase \; EC=3.1.1.- \; | Citrobacter youngae ATCC 29220 |
| 9entr-s3is61 | Cedecea davisae DSM 4568 Acetyl esterase \; EC=3.1.1.- \; | Cedecea davisae DSM 4568 |
| 9gamm-a0a034t2u0 | Edwardsiella piscicida\; Edwardsiella anguillarum Acetyl esterase \; EC=3.1.1.- \; | Edwardsiella piscicida |
| 9gamm-a0a085hgd3 | Leminorella grimontii ATCC 33999 = DSM 5078 Acetyl esterase \; EC=3.1.1.- \; | Leminorella grimontii ATCC 33999 = DSM 5078 |
| 9gamm-a0a0g4qdg4 | Proteus penneri Acetyl esterase \; EC=3.1.1.- \; | Proteus penneri |
| 9gamm-a0a2a2ma72 | Hafnia paralvei\; Enterobacteriaceae bacterium\; Hafnia alvei Acetyl esterase \; EC=3.1.1.- \; | Hafnia paralvei |
| 9gamm-a0a2x4utt1 | Leminorella richardii Acetyl esterase \; EC=3.1.1.- \; | Leminorella richardii |
| 9gamm-a0a345lvb8 | Providencia huaxiensis Acetyl esterase \; EC=3.1.1.- \; | Providencia huaxiensis |
| 9gamm-a0a376d9q9 | Edwardsiella hoshinae Acetyl esterase \; EC=3.1.1.- \; | Edwardsiella hoshinae |
| 9gamm-a0a3d2bn18 | Proteus sp. (in: enterobacteria)\; Proteus hauseri Acetyl esterase \; EC=3.1.1.- \; | Proteus sp. (in: enterobacteria) |
| 9gamm-a0a411wlq4 | Jinshanibacter zhutongyuii Acetyl esterase \; EC=3.1.1.- \; | Jinshanibacter zhutongyuii |
| 9gamm-a0a4v2v3x1 | Providencia alcalifaciens\; Providencia sp. Acetyl esterase \; EC=3.1.1.- \; | Providencia alcalifaciens |
| 9gamm-a0a6g6pl23 | Providencia sp. Acetyl esterase \; EC=3.1.1.- \; | Providencia sp. |
| 9gamm-a0a6i7dea3 | Proteus columbae\; Proteus vulgaris Acetyl esterase \; EC=3.1.1.- \; | Proteus columbae |
| 9gamm-a0a6l6fz53 | Providencia sp.\; Providencia rettgeri Acetyl esterase \; EC=3.1.1.- \; | Providencia sp. |
| 9gamm-a0a806z0g4 | Obesumbacterium proteus Acetyl esterase \; EC=3.1.1.- \; | Obesumbacterium proteus |
| 9gamm-a0a9d7fr68 | Insectihabitans xujianqingii Acetyl esterase \; EC=3.1.1.- \; | Insectihabitans xujianqingii |
| 9gamm-b6xez2 | Providencia alcalifaciens DSM 30120 Acetyl esterase \; EC=3.1.1.- \; | Providencia alcalifaciens DSM 30120 |
| acilw-a0a1p8kgg3 | Acinetobacter lwoffii\; Moraxella osloensis\; Proteus terrae subsp.Proteus vulgaris Putative acetyl esterase | Acinetobacter lwoffii |
| citam-a0a0f6tt31 | Citrobacter amalonaticus Acetyl esterase \; EC=3.1.1.- \; | Citrobacter amalonaticus |
| citam-a0a2s4s0b3 | Citrobacter amalonaticus Acetyl esterase \; EC=3.1.1.- \; | Citrobacter amalonaticus |
| citam-a0a9c7qnd9 | Citrobacter amalonaticus Acetyl esterase \; EC=3.1.1.- \; | Citrobacter amalonaticus |
| citbr-a0a1v8p130 | Citrobacter braakii\; Citrobacter freundii complex sp.\; Citrobacter sp.\; Acetyl esterase \; EC=3.1.1.- \; | Citrobacter braakii |
| citfr-a0a336qmp4 | Citrobacter freundii Acetyl esterase \; EC=3.1.1.- \; | Citrobacter freundii |
| citfr-a0a7d6pp02 | Citrobacter freundii Acetyl esterase \; EC=3.1.1.- \; | Citrobacter freundii |
| citfr-a0a7w2wqc4 | Citrobacter freundii Acetyl esterase \; EC=3.1.1.- \; | Citrobacter freundii |
| citk8-a8ajw7 | Citrobacter koseri (Citrobacter diversus, strain ATCC BAA-895 \/ CDC 4225-83 \/ SGSC4696) Acetyl esterase \; EC=3.1.1.- \; | Citrobacter koseri |
| citro-a0a482pvr2 | Citrobacter rodentium (Citrobacter freundii biotype 4280) Acetyl esterase \; EC=3.1.1.- \; | Citrobacter rodentium |
| ecoli-Aes |  Escherichia coli, Escherichia fergusonii, acetylesterase lipase like enzyme YBAC Aes Escherichia fergusonii |
Escherichia coli |
| edwi9-c5b8r9 | Edwardsiella ictaluri (strain 93-146) Acetyl esterase \; EC=3.1.1.- \; | Edwardsiella ictaluri |
| edwta-a0a2a7u0n0 | Edwardsiella tarda Acetyl esterase \; EC=3.1.1.- \; | Edwardsiella tarda |
| edwte-d0zcg7 | Edwardsiella tarda\; Edwardsiella piscicida Acetyl esterase \; EC=3.1.1.- \; | Edwardsiella tarda |
| entbf-l0m5s7 | Enterobacteriaceae bacterium (strain FGI 57) Acetyl esterase \; EC=3.1.1.- \; | Enterobacteriaceae bacterium |
| hafal-a0a097r6i2 | Hafnia alvei Acetyl esterase \; EC=3.1.1.- \; | Hafnia alvei |
| hafal-a0a377pad8 | Hafnia alvei Acetyl esterase \; EC=3.1.1.- \; | Hafnia alvei |
| hafal-a0a377ppd3 | Hafnia alvei Acetyl esterase \; EC=3.1.1.- \; | Hafnia alvei |
| prore-a0a264vva6 | Providencia rettgeri\; Providencia sp. Acetyl esterase \; EC=3.1.1.- \; | Providencia rettgeri |
| prore-a0a379fsz6 | Providencia rettgeri Acetyl esterase \; EC=3.1.1.- \; | Providencia rettgeri |
| provu-a0a379fag8 | Proteus vulgaris Acetyl esterase \; EC=3.1.1.- \; | Proteus vulgaris |
| provu-a0a6g6sp08 | Proteus vulgaris Acetyl esterase \; EC=3.1.1.- \; | Proteus vulgaris |
| salty-AES | Salmonella typhi, S. typhimurium, S. paratyphi, S. cholerae suis, S. agona, S. dublin, S. enteritidis, S. newport, S. schwarzengrund, acetyl esterase (EC 3.1.1.-) |
Salmonella typhi |
| serfo-a0a542bk83 | Serratia fonticola Acetyl esterase \; EC=3.1.1.- \; | Serratia fonticola |
| shifl-AES | Shigella flexneri, Shigella sonnei, Shigella boydii, Shigella dysenteriae, putative lipase (EC 3.1.1.-) | Shigella flexneri |
| Inhibitor | Chemical Nomenclature | Proteins |
|---|---|---|
| PMSF | Phenylmethylsulfonyl fluoride | theet-q3ch51 emeni-q5avy9 human-ABHD10 human-PREPL myctu-Rv1430 psefl-cxest 9bact-E40 thefu-q6a0i4 ecoli-Aes orysj-Q10QA5 bac25-mglp 9bact-Q0GMU2 bacsu-FENB psepu-clcd1 thema-TM0077 bacsu-RsbQ ecoli-bioh drome-CG9542 human-FAP tubmm-TmEst2 human-NOTUM cutac-e6dae5 9gamm-urc15994 9baci-EstD9 geost-est30 pholl-AntI |
| Tetraethylene-glycol | 2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethanol | mouse-ACHE sulso-SSO2518 canan-lipasA soltu-3epoxy strco-SC3F7.14 amyme-RIFR arcfu-AF1763 ecoli-Aes agrvs-b9jym4 |
| Triethylene-glycol | 2-[2-(2-hydroxyethoxy)ethoxy]ethanol | torca-ACHE ecoli-Aes |
References (3)
| Title : Structural and mutational analyses of Aes, an inhibitor of MalT in Escherichia coli - Schiefner_2014_Proteins_82_268 |
| Author(s) : Schiefner A , Gerber K , Brosig A , Boos W |
| Ref : Proteins , 82 :268 , 2014 |
| Abstract : |
| PubMedSearch : Schiefner_2014_Proteins_82_268 |
| PubMedID: 23934774 |
| Gene_locus related to this paper: ecoli-Aes |
| Title : The Aes protein and the monomeric alpha-galactosidase from Escherichia coli form a non-covalent complex. Implications for the regulation of carbohydrate metabolism - Mandrich_2002_J.Biol.Chem_277_48241 |
| Author(s) : Mandrich L , Caputo E , Martin BM , Rossi M , Manco G |
| Ref : Journal of Biological Chemistry , 277 :48241 , 2002 |
| Abstract : |
| PubMedSearch : Mandrich_2002_J.Biol.Chem_277_48241 |
| PubMedID: 12374803 |
| Gene_locus related to this paper: ecoli-Aes |
| Title : The Aes protein directly controls the activity of MalT, the central transcriptional activator of the Escherichia coli maltose regulon - Joly_2002_J.Biol.Chem_277_16606 |
| Author(s) : Joly N , Danot O , Schlegel A , Boos W , Richet E |
| Ref : Journal of Biological Chemistry , 277 :16606 , 2002 |
| Abstract : |
| PubMedSearch : Joly_2002_J.Biol.Chem_277_16606 |
| PubMedID: 11867639 |
| Gene_locus related to this paper: ecoli-Aes |