Mycobacterium tuberculosis, Mycobacterium bovis, MT1474, Rv1430 PE family protein PE16
Esterase that hydrolyzes short to medium chain fatty acid esters with the highest specific activity for p-nitrophenyl caproate (pNPC6). Has lower activity with p-nitrophenyl caprylate (pNPC8) and p-nitrophenyl butyrate (pNPC4). Has weak activity with p-nitrophenyl caprate (pNPC10) and p-nitrophenyl laurate (pNPC12). Does not possess lipolytic activity and cutinase activity. There are more than 1000 strains. Other Uniprot entries and list of strains can be found with the link: Other strains
Family : PE-PPE
Block : X
Position in NCBI Life Tree : Mycobacterium tuberculosis
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms N E > Bacteria N E > Terrabacteria group N E > Actinobacteria [phylum] N E > Actinobacteria [class] N E > Corynebacteriales N E > Mycobacteriaceae N E > Mycobacterium N E > Mycobacterium tuberculosis complex N E > Mycobacterium tuberculosis N EMSFVFAVPEM VAATASDLAS LGAALSEATA AAAIPTTQVL AAAADEVSAA IAELFGAHGQ EFQALSAQAS AFHDRFVRAL SAAAGWYVDA EAANAALVDT AATGASELGS GGRTALILGS TGTPRPPFDY MQQVYDRYIA PHYLGYAFSG LYTPAQFQPW TGIPSLTYDQ SVAEGAGYLH TAIMQQVAAG NDVVVLGFSQ GASVATLEMR HLASLPAGVA PSPDQLSFVL LGNPNNPNGG ILARFPGLYL QSLGLTFNGA TPDTDYATTI YTTQYDGFAD FPKYPLNILA DVNALLGIYY SHSLYYGLTP EQVASGIVLP VSSPDTNTTY ILLPNEDLPL LQPLRGIVPE PLLDLIEPDL RAIIELGYDR TGYADVPTPA ALFPVHIDPI AVPPQIGAAI GGPLTALDGL LDTVINDQLN PVVTSGIYQA GAELSVAAAG YGAPAGVTNA IFIGQQVLPI LVEGPGALVT ADTHYLVDAI QDLAAGDLSG FNQNLQLIPA TNIALLVFAA GIPAVAAVAI LTGQDFPV
Title : The PE16 (Rv1430) of Mycobacterium tuberculosis Is an Esterase Belonging to Serine Hydrolase Superfamily of Proteins - Sultana_2013_PLoS.One_8_e55320 |
Author(s) : Sultana R , Vemula MH , Banerjee S , Guruprasad L |
Ref : PLoS ONE , 8 :e55320 , 2013 |
Abstract : |
PubMedSearch : Sultana_2013_PLoS.One_8_e55320 |
PubMedID: 23383323 |
Gene_locus related to this paper: myctu-Rv1430 |