Plant_lipase_EDS1-like
Relationship
Comment
Enhanced Disease Susceptibility 1 (EDS1), an essential component of R gene-mediated disease resistance. The Arabidopsis EDS1 (arath-eds1) and (phytoalexin-deficient 4) PAD4 (arath-PAD4) genes encode lipase-like proteins that function in resistance (R) gene-mediated and basal plant disease resistance. EDS1 can dimerize and interact with PAD4. EDS1 (arath-eds1) and PAD4 (arath-PAD4) genes encode lipase-like proteins that function in resistance (R) gene-mediated and basal plant disease resistance. EDS1 can dimerize and interact with PAD4 or with SAG101 (arath-At5g14930). This family is extracted from the Lipase3 gene family. The C-terminal domain known as the EP domain and its interface consists of hydrophobic interactions, salt bridges, and an extensive hydrogen bonding network. Plants utilise intracellular nucleotide-binding, leucine-rich repeat (NLR) immune receptors to detect pathogen effectors and activate local and systemic defence. NRG1 and ADR1 'helper' NLRs (RNLs) cooperate with enhanced disease susceptibility 1 (EDS1), senescence-associated gene 101 (SAG101) and phytoalexin-deficient 4 (PAD4) lipase-like proteins to mediate signalling from TIR domain NLR receptors (TNLs). Two distinct modules (NRG1/EDS1/SAG101 and ADR1/EDS1/PAD4) mediate TNL receptor defence signalling. (In the seed alignment and the HMM alignement the EP domain (not alpha/beta hydrolase domain) is excluded)
Database
Interpro : IPR000734 Lipase , IPR044214 EDS1-like , IPR041266 EDS1, EP domain EDS1_EP
PIRSF : No PIRSF
Pdoc : PDOC00110
Pfam : PF01764 Lipase_3 , PF18117 EDS1_EP
Prints : PR00821
EC Number : No EC Number
Sequences
| Peptide in | Fasta |
| Nucleotide in | Fasta |
| Alignment with Multalin | Text only |
| Seed alignment with MAFFT | No colour / coloured with Mview |
| Alignment with MAFFT | No colour / coloured with Mview |
| Dendrogram | The dnd file |
| Structure | Name | Proteins |
|---|---|---|
| 8ZWA | At EDS1-PAD4-ADR1 heterotrimer by HopBY | arath-eds1 arath-PAD4 |
| 8ZW9 | At EDS1-PAD4-ADR1 heterotrimer by RPS4 | arath-eds1 arath-PAD4 |
| 8ZF0 | pRib-ADP bound OsEDS1-PAD4-ADR1 complex | orysa-q6h415 orysa-q53lh1 |
| 8B28 | Vitis vinifera N-terminal domain of EDS1. VvEDS1 Nterm | vitvi-f6gsx7 |
| 7XDD | Cryo-EM structure of Arabidopsis thaliana lipase EDS1 (Enhanced disease susceptibility 1-like) and PAD4(phytoalexin-deficient 4) | arath-eds1 arath-PAD4 |
| 7XEY | EDS1-PAD4 complexed with pRib-ADP | arath-eds1 arath-PAD4 |
| 8YL6 | EDS1-SAG101-NRG1.1 L134E heterotrimer | arath-eds1 arath-At5g14930 |
| 8YL7 | EDS1-SAG101-NRG1.3 E heterotrimer | arath-eds1 arath-At5g14930 |
| 7XJP | Cryo-EM structure of EDS1 and SAG101 with ATP-APDR | arath-eds1 arath-At5g14930 |
| 6I8G | Structure of the plant immune signaling node EDS1 (enhanced disease susceptibility 1) in complex with nanobody ENB73 | arath-eds1 |
| 6I8H | Structure of the plant immune signaling node EDS1 (enhanced disease susceptibility 1) in complex with nanobody ENB15 | arath-eds1 |
| 6Q6Z | Structure of the plant immune signaling node EDS1 (enhanced disease susceptibility 1) in complex with nanobody ENB21 | arath-eds1 |
| 4NFU | Structure of the central plant immunity signaling node EDS1 in complex with its interaction partner SAG101 | arath-eds1 arath-At5g14930 |
| Gene_locus | Name | Species |
|---|---|---|
| arath-At5g14930 |  Arabidopsis thaliana (Mouse-ear cress) At5g14930 sag101 AtSAG101 |
Arabidopsis thaliana |
| arath-eds1 | Arabidopsis thaliana lipase homolog (EDS1) (Enhanced disease susceptibility 1-like) At3g48090 AtEDS1 |
Arabidopsis thaliana |
| arath-PAD4 | Arabidopsis thaliana (Mouse-ear cress) PAD4 lipase 61.0 kda protein EDS9 At3g52430 AtPAD4 (phytoalexin-deficient 4) |
Arabidopsis thaliana |
| arath-T17F15.50 | Arabidopsis thaliana (Mouse-ear cress) =Enhanced disease susceptibility 1 protein B EDS1B At3g48080\/T17F15_50 | Arabidopsis thaliana |
| lyces-q56r03 | Lycopersicon esculentum (Tomato)(Solanum lycopersicum) eds1 | Lycopersicon esculentum |
| medtr-q1s9m3 | Medicago truncatula (Barrel medic) Enhanced disease susceptibility protein | Medicago truncatula |
| nicbe-Q8S3U2 | Nicotiana benthamiana eds1-like protein | Nicotiana benthamiana |
| nicta-Q8LL12 | Nicotiana tabacum (Common tobacco) eds1 | Nicotiana tabacum |
| orysa-q6h415 | Oryza sativa (japonica cultivar-group) enhanced disease susceptibility 1 EDS1 \; O. meridionalis\; O. barthii\; O. nivara\; O. rufipogon\; O. glumipatula\; O. punctataputative O. brachyantha |
Oryza sativa |
| orysa-q53lh1 | Oryza sativa subsp. indica subsp. japonica (Rice) PAD4 lipase (phytoalexin-deficient 4) lipase, putative |
Oryza sativa |
| soltu-q2tnk2 | Solanum tuberosum (Potato) phytoalexin-deficient 4-2 protein | Solanum tuberosum |
| soltu-q2tnk3 | Solanum tuberosum (Potato) phytoalexin-deficient 4-1 protein | Solanum tuberosum |
| soltu-q2tqv0 | Solanum tuberosum (Potato) enhanced disease susceptibility 1 protein | Solanum tuberosum |
| arall-d7lri7 | Arabidopsis lyrata subsp. lyrata (Lyre-leaved rock-cress). Enhanced disease susceptibility 1 | Arabidopsis lyrata subsp. lyrata |
| 9bras-r0fme4 | Capsella rubella. Uncharacterized protein | Capsella rubella |
| 9bras-a0a565btv1 | Arabis nemorensis. Uncharacterized protein | Arabis nemorensis |
| 9bras-a0a6d2ju25 | Microthlaspi erraticum. Uncharacterized protein | Microthlaspi erraticum |
| araal-a0a087gz21 | Arabis alpina (Alpine rock-cress). Uncharacterized protein | Arabis alpina |
| araal-a0a087h4k1 | Arabis alpina (Alpine rock-cress). Uncharacterized protein | Arabis alpina |
| eutsa-v4nhr8 | Eutrema salsugineum (Saltwater cress) (Sisymbrium salsugineum). Uncharacterized protein | Eutrema salsugineum |
| rapsa-a0a6j0jyp3 | Raphanus sativus (Radish) (Raphanus raphanistrum var. sativus). protein EDS1B-like | Raphanus sativus |
| bracm-a0a397z0i0 | Brassica campestris (Field mustard). Uncharacterized protein | Brassica campestris |
| brana-a0a078i6d2 | Brassica napus (Rape)\; Brassica oleracea var. oleracea. BnaCnng12090D protein | Brassica napus |
| brana-a0a078jku0 | Brassica napus (Rape). BnaAnng26220D protein | Brassica napus |
| rapsa-a0a6j0lzs2 | Raphanus sativus (Radish) (Raphanus raphanistrum var. sativus). protein EDS1B-like | Raphanus sativus |
| brarp-m4dnj8 | Brassica rapa subsp. pekinensis (Chinese cabbage) (Brassica pekinensis). Uncharacterized protein | Brassica rapa subsp. pekinensis |
| bracm-a0a398apg3 | Brassica campestris (Field mustard). (field mustard) hypothetical protein | Brassica campestris |
| brarp-m4ey83 | Brassica rapa subsp. pekinensis (Chinese cabbage) (Brassica pekinensis). Uncharacterized protein | Brassica rapa subsp. pekinensis |
| bracr-a0a3n6rng7 | Brassica cretica (Mustard). Uncharacterized protein | Brassica cretica |
| bracr-a0a3n6rj72 | Brassica cretica (Mustard). Uncharacterized protein | Brassica cretica |
| bracm-a0a398ars4 | Brassica campestris (Field mustard). Uncharacterized protein | Brassica campestris |
| brarp-m4ey84 | Brassica rapa subsp. pekinensis (Chinese cabbage) (Brassica pekinensis). Uncharacterized protein | Brassica rapa subsp. pekinensis |
| rapsa-a0a6j0lba8 | Raphanus sativus (Radish) (Raphanus raphanistrum var. sativus). protein EDS1B-like | Raphanus sativus |
| braol-a0a0d3a922 | Brassica oleracea var. oleracea. Uncharacterized protein | Brassica oleracea var. oleracea |
| triwf-a0a7j7c8l4 | Tripterygium wilfordii (Thunder God vine). Putative Disease resistance protein | Tripterygium wilfordii |
| durzi-a0a6p5xhu8 | Durio zibethinus (Durian). protein EDS1 | Durio zibethinus |
| hibsy-a0a6a3ah98 | Hibiscus syriacus (Rose of Sharon). Zinc finger CCCH domain-containing protein 5-like isoform X1 | Hibiscus syriacus |
| gosra-a0a0d2pzd7 | Gossypium raimondii (New World cotton)\; G. hirsutum\; G. mustelinum\; G. aridum\; G. harknessii\; G. lobatum\; G. australe\; G. armourianum\; G. klotzschianum\; G. davidsonii\; G. schwendimanii\; G. laxum\; G. trilobum\; G. gossypioides. protein EDS1-like | Gossypium raimondii |
| hibsy-a0a6a2x6u9 | Hibiscus syriacus (Rose of Sharon). Zinc finger CCCH domain-containing protein 5-like isoform X1 | Hibiscus syriacus |
| cepfo-a0a1q3c2e8 | Cephalotus follicularis (Albany pitcher plant). Lipase_3 domain-containing protein | Cephalotus follicularis |
| 9rosi-a0a5c7hxy4 | Acer yangbiense. Uncharacterized protein | Acer yangbiense |
| 9rosi-a0a6j1b058 | Herrania umbratica. protein EDS1L-like | Herrania umbratica |
| thecc-a0a061fu06 | Theobroma cacao (Cacao) (Cocoa). Disease resistance protein, putative | Theobroma cacao |
| cajca-a0a151rwt3 | Cajanus cajan (Pigeon pea) (Cajanus indicus). Uncharacterized protein | Cajanus cajan |
| 9rosi-a0a1r3kqf1 | Corchorus olitorius. Lipase, class 3 | Corchorus olitorius |
| camsi-a0a7j7g2i2 | Camellia sinensis (Tea). Uncharacterized protein | Camellia sinensis |
| cofar-a0a6p6xdj0 | Coffea arabica (Arabian coffee). protein EDS1-like | Coffea arabica |
| citcl-v4syg1 | Citrus clementina (Clementine) (Citrus deliciosa x Citrus sinensis)\; Citrus unshiu (Satsuma mandarin) (Citrus nobilis var. unshiu)\; Citrus sinensis (Sweet orange) (Citrus aurantium var. sinensis). Uncharacterized protein | Citrus clementina |
| salsn-a0a4d8yvp8 | Salvia splendens (Scarlet sage). Enhanced disease susceptibility 1 protein | Salvia splendens |
| 9rosi-a0a5c7h0k5 | Acer yangbiense. Uncharacterized protein | Acer yangbiense |
| artan-a0a2u1qgg7 | Artemisia annua (Sweet wormwood). Protein EDS1L | Artemisia annua |
| soltu-m1d6d0 | Solanum tuberosum (Potato). Enhanced disease susceptibility 1 protein | Solanum tuberosum |
| cofar-a0a6p6xcv5 | Coffea arabica (Arabian coffee)\; Coffea canephora (Robusta coffee). protein EDS1-like | Coffea arabica |
| citcl-v4say8 | Citrus clementina (Clementine) (Citrus deliciosa x Citrus sinensis). Uncharacterized protein | Citrus clementina |
| lupal-a0a6a5lz53 | Lupinus albus (White lupine) (Lupinus termis). Putative carboxylesterase | Lupinus albus |
| camsi-a0a4v3wr80 | Camellia sinensis var. sinensis. Uncharacterized protein | Camellia sinensis var. sinensis |
| soybn-i1jx17 | Glycine max (Soybean) (Glycine hispida). . Protein EDS1 | Glycine max |
| 9astr-a0a5n6pcv4 | Mikania micrantha. Uncharacterized protein | Mikania micrantha |
| sesin-a0a6i9snr9 | Sesamum indicum (Oriental sesame) (Sesamum orientale). protein EDS1B | Sesamum indicum |
| salsn-a0a4d9brx8 | Salvia splendens (Scarlet sage). Enhanced disease susceptibility 1 protein | Salvia splendens |
| hevbr-a0a6a6mdr9 | Hevea brasiliensis (Para rubber tree) (Siphonia brasiliensis). Uncharacterized protein | Hevea brasiliensis |
| lacsa-a0a2j6l4a3 | Lactuca sativa (Garden lettuce). Uncharacterized protein | Lactuca sativa |
| helan-a0a251vi64 | Helianthus annuus (Common sunflower). Uncharacterized protein | Helianthus annuus |
| daucs-a0a164ul57 | Daucus carota subsp. sativus (Carrot). Uncharacterized protein | Daucus carota subsp. sativus |
| cucma-a0a6j1jlb1 | Cucurbita maxima (Pumpkin) (Winter squash). protein EDS1L-like | Cucurbita maxima |
| soybn-k7kvv2 | Glycine max (Soybean) (Glycine hispida)\; Glycine soja (Wild soybean). Protein EDS1L | Glycine max |
| actcc-a0a2r6qgs9 | Actinidia chinensis var. chinensis (Chinese soft-hair kiwi)\; Actinidia rufa. Protein EDS1B like | Actinidia chinensis var. chinensis |
| 9lami-a0a2g9gi00 | Handroanthus impetiginosus. Carboxylesterase | Handroanthus impetiginosus |
| lupal-a0a6a5mjk3 | Lupinus albus (White lupine) (Lupinus termis). Putative carboxylesterase | Lupinus albus |
| manes-a0a2c9ujk6 | Manihot esculenta (Cassava) (Jatropha manihot). Uncharacterized protein | Manihot esculenta |
| quelo-a0a7n2rbl4 | Quercus lobata (Valley oak). Uncharacterized protein | Quercus lobata |
| capan-a0a1u8hd13 | Capsicum annuum (Capsicum pepper)\; Capsicum baccatum (Peruvian pepper). Uncharacterized protein | Capsicum annuum |
| tobac-a0a1s3z3r8 | Nicotiana tabacum (Common tobacco). protein EDS1L-like | Nicotiana tabacum |
| aquca-a0a2g5f324 | Aquilegia coerulea (Rocky mountain columbine). Uncharacterized protein | Aquilegia coerulea |
| vigrr-a0a3q0ez52 | Vigna radiata var. radiata (Mung bean) (Phaseolus aureus). protein EDS1L | Vigna radiata var. radiata |
| popal-a0a4u5qy13 | Populus alba (White poplar). Enhanced disease susceptibility 1 family protein | Populus alba |
| manes-a0a2c9vrv8 | Manihot esculenta (Cassava) (Jatropha manihot). Uncharacterized protein | Manihot esculenta |
| nelnu-a0a1u8ave7 | Nelumbo nucifera (Sacred lotus). protein EDS1L-like | Nelumbo nucifera |
| jugre-a0a2i4fj48 | Juglans regia (English walnut). protein EDS1L-like | Juglans regia |
| phaan-a0a0l9uc60 | Phaseolus angularis (Azuki bean) (Vigna angularis). Uncharacterized protein | Phaseolus angularis |
| cucme-a0a1s3buy6 | Cucumis melo (Muskmelon). protein EDS1L-like | Cucumis melo |
| aradu-a0a6p4dix2 | Arachis duranensis (Wild peanut)\; Arachis hypogaea (Peanut). protein EDS1L | Arachis duranensis |
| jatcu-a0a067k816 | Jatropha curcas (Barbados nut). Uncharacterized protein | Jatropha curcas |
| phavu-v7azs2 | Phaseolus vulgaris (Kidney bean) (French bean). Uncharacterized protein | Phaseolus vulgaris |
| ricco-b9r8z8 | Ricinus communis (Castor bean). Lipase, putative | Ricinus communis |
| rosch-a0a2p6p278 | Rosa chinensis (China rose). Putative carboxylesterase | Rosa chinensis |
| poptr-b9iek5 | Populus trichocarpa (Western balsam poplar) (Populus balsamifera subsp. trichocarpa). Uncharacterized protein | Populus trichocarpa |
| quelo-a0a7n2mne3 | Quercus lobata (Valley oak). Uncharacterized protein | Quercus lobata |
| momch-a0a6j1c0s2 | Momordica charantia (Bitter gourd) (Balsam pear). protein EDS1L-like | Momordica charantia |
| cucsa-a0a0a0ls66 | Cucumis sativus (Cucumber). Uncharacterized protein | Cucumis sativus |
| tobac-a0a1s4bsf2 | Nicotiana tabacum (Common tobacco)\; Nicotiana sylvestris (Wood tobacco) (South American tobacco)\; Nicotiana attenuata (Coyote tobacco). protein EDS1L-like | Nicotiana tabacum |
| cajca-a0a151rx08 | Cajanus cajan (Pigeon pea) (Cajanus indicus). Uncharacterized protein | Cajanus cajan |
| 9rosa-w9qzg2 | Morus notabilis. Uncharacterized protein | Morus notabilis |
| spiol-a0a0k9r6e9 | Spinacia oleracea (Spinach). Uncharacterized protein | Spinacia oleracea |
| lupan-a0a1j7h5s4 | Lupinus angustifolius (Narrow-leaved blue lupine). Uncharacterized protein | Lupinus angustifolius |
| cucma-a0a6j1i8e2 | Cucurbita maxima (Pumpkin) (Winter squash). protein EDS1L-like | Cucurbita maxima |
| cicar-a0a1s2ykn9 | Cicer arietinum (Chickpea) (Garbanzo). protein EDS1L-like | Cicer arietinum |
| eucgr-a0a059a7m2 | Eucalyptus grandis (Flooded gum). Uncharacterized protein | Eucalyptus grandis |
| treoi-a0a2p5ekk2 | Trema orientale (Charcoal tree) (Celtis orientalis). Alpha\/beta-hydrolase | Trema orientale |
| 9magn-a0a200qv20 | Macleaya cordata. Lipase | Macleaya cordata |
| eucgr-a0a059a6p6 | Eucalyptus grandis (Flooded gum). Uncharacterized protein | Eucalyptus grandis |
| cicar-a0a1s2yak2 | Cicer arietinum (Chickpea) (Garbanzo). protein EDS1L-like | Cicer arietinum |
| 9rosi-a0a5n5kbl1 | Salix brachista. Uncharacterized protein | Salix brachista |
| 9lami-a0a2z7bgj4 | Dorcoceras hygrometricum. Uncharacterized protein | Dorcoceras hygrometricum |
| quelo-a0a7n2mpu3 | Quercus lobata (Valley oak). Uncharacterized protein | Quercus lobata |
| kalfe-a0a7n0tzs6 | Kalanchoe fedtschenkoi (Lavender scallops) (South American air plant). Uncharacterized protein | Kalanchoe fedtschenkoi |
| cansa-a0a7j6fzj4 | Cannabis sativa (Hemp) (Marijuana). Uncharacterized protein | Cannabis sativa |
| medtr-a0a072v056 | Medicago truncatula (Barrel medic) (Medicago tribuloides).. Enhanced disease susceptibility protein | Medicago truncatula |
| vitvi-f6gsx7 | Vitis vinifera (Grape).Enhanced disease susceptibility 1 EDS1 VvEDS1Nterm |
Vitis vinifera |
| aradu-a0a6p4dpj0 | Arachis duranensis (Wild peanut)\; Arachis hypogaea (Peanut). protein EDS1L isoforms | Arachis duranensis |
| poptr-a9pfg4 | Populus trichocarpa (Western balsam poplar) (Populus balsamifera subsp. trichocarpa). Uncharacterized protein | Populus trichocarpa |
| cajca-a0a151rws4 | Cajanus cajan (Pigeon pea) (Cajanus indicus). Uncharacterized protein | Cajanus cajan |
| popal-a0a4u5mi39 | Populus alba (White poplar). Enhanced disease susceptibility 1 family protein | Populus alba |
| nelnu-a0a1u7yn26 | Nelumbo nucifera (Sacred lotus). protein EDS1-like | Nelumbo nucifera |
| soybn-i1kcl6 | Glycine max (Soybean) (Glycine hispida)\; Glycine soja (Wild soybean). Protein EDS1L | Glycine max |
| eucgr-a0a059a6p1 | Eucalyptus grandis (Flooded gum). Uncharacterized protein | Eucalyptus grandis |
| parad-a0a2p5a5v0 | Parasponia andersonii (Sponia andersonii). Alpha\/beta-hydrolase | Parasponia andersonii |
| eucgr-a0a059a5e9 | Eucalyptus grandis (Flooded gum). Uncharacterized protein | Eucalyptus grandis |
| musam-a0a804kav5 | Musa acuminata subsp. malaccensis (Wild banana) (Musa malaccensis)\; Musa balbisiana (Banana). Uncharacterized protein | Musa acuminata subsp. malaccensis |
| prupe-m5wr61 | Prunus persica (Peach) (Amygdalus persica)\; Prunus dulcis (Almond) (Amygdalus dulcis)\; Prunus yedoensis var. nudiflora. lipase PAD4 | Prunus persica |
| vigrr-a0a1s3twy0 | Vigna radiata var. radiata (Mung bean) (Phaseolus aureus). protein EDS1L | Vigna radiata var. radiata |
| phaan-a0a0l9ucr8 | Phaseolus angularis (Azuki bean) (Vigna angularis)\; Vigna angularis var. angularis. Uncharacterized protein | Phaseolus angularis |
| 9aste-a0a5j5bf24 | Nyssa sinensis. Uncharacterized protein | Nyssa sinensis |
| soybn-i1kcl7 | Glycine max (Soybean) (Glycine hispida)\; Glycine soja (Wild soybean). Protein EDS1B | Glycine max |
| pungr-a0a218xzu6 | Punica granatum (Pomegranate). Uncharacterized protein | Punica granatum |
| elagv-a0a6i9rtu7 | Elaeis guineensis var. tenera (Oil palm). protein EDS1B | Elaeis guineensis var. tenera |
| 9oryz-a0a0d9xdd7 | Leersia perrieri. Uncharacterized protein | Leersia perrieri |
| thath-a0a7j6x5g3 | Thalictrum thalictroides (Rue-anemone) (Anemone thalictroides). Enhanced disease susceptibility | Thalictrum thalictroides |
| pruar-a0a6j5xc26 | Prunus armeniaca (Apricot) (Armeniaca vulgaris). Uncharacterized protein | Prunus armeniaca |
| maldo-eds1l.1 | Malus domestica (Apple) (Pyrus malus). Uncharacterized protein | Malus domestica |
| maldo-eds1l.2 | Malus domestica (Apple) (Pyrus malus). Uncharacterized protein | Malus domestica |
| malba-a0a540lik7 | Malus baccata (Siberian crab apple) (Pyrus baccata). Uncharacterized protein | Malus baccata |
| 9poal-a0a5j9tem6 | Eragrostis curvula (weeping love grass). Uncharacterized protein | Eragrostis curvula |
| daucs-a0a164ul46 | Daucus carota subsp. sativus (Carrot). Uncharacterized protein | Daucus carota subsp. sativus |
| rosch-a0a2p6s545 | Rosa chinensis (China rose). Putative carboxylesterase | Rosa chinensis |
| setit-k3zri0 | Setaria italica (Foxtail millet) (Panicum italicum)\; (Setaria italica subsp. viridis). Uncharacterized protein | Setaria italica |
| horvv-a0a287rem5 | Hordeum vulgare subsp. vulgare (Domesticated barley). Uncharacterized protein | Hordeum vulgare subsp. vulgare |
| ensve-a0a444fr62 | Ensete ventricosum (Abyssinian banana) (Musa ensete). Uncharacterized protein | Ensete ventricosum |
| pruye-a0a314xzw3 | Prunus yedoensis var. nudiflora. Uncharacterized protein | Prunus yedoensis var. nudiflora |
| elagv-a0a6i9set9 | Elaeis guineensis var. tenera (Oil palm). protein EDS1B | Elaeis guineensis var. tenera |
| bradi-a0a0q3lc91 | Brachypodium distachyon (Purple false brome) (Trachynia distachya). Uncharacterized protein | Brachypodium distachyon |
| panmi-a0a3l6ta96 | Panicum miliaceum (Proso millet) (Broomcorn millet)\; Panicum hallii var. hallii. Protein EDS1L-like | Panicum miliaceum |
| wheat-a0a1d5zte7 | Triticum aestivum (Wheat)\; Aegilops tauschii subsp. strangulata (Goatgrass)\; Triticum turgidum. Enhanced disease susceptibility 1 | Triticum aestivum |
| phavu-v7awu7 | Phaseolus vulgaris (Kidney bean) (French bean). Uncharacterized protein | Phaseolus vulgaris |
| daucs-a0a164v6h1 | Daucus carota subsp. sativus (Carrot). Uncharacterized protein | Daucus carota subsp. sativus |
| jugre-a0a2i4flz2 | Juglans regia (English walnut). protein EDS1B-like | Juglans regia |
| anaco-a0a199udn0 | Ananas comosus (Pineapple) (Ananas ananas). Protein EDS1L | Ananas comosus |
| 9rosi-a0a5n6rnz1 | Carpinus fangiana. Uncharacterized protein | Carpinus fangiana |
| sorbi-a0a1b6qcb9 | Sorghum bicolor (Sorghum) (Sorghum vulgare). Uncharacterized protein | Sorghum bicolor |
| 9rosa-a0a5n5idf0 | Pyrus ussuriensis x Pyrus communis. Uncharacterized protein | Pyrus ussuriensis x Pyrus communis |
| pungr-a0a2i0lbi1 | Punica granatum (Pomegranate). Uncharacterized protein | Punica granatum |
| malba-a0a540lik0 | Malus baccata (Siberian crab apple) (Pyrus baccata). Uncharacterized protein | Malus baccata |
| malba-a0a540lri2 | Malus baccata (Siberian crab apple) (Pyrus baccata)\; Malus domestica (Apple) (Pyrus malus). Uncharacterized protein | Malus baccata |
| arahy-a0a445d0e9 | Arachis hypogaea (Peanut). Uncharacterized protein | Arachis hypogaea |
| aradu-a0a6p4dix7 | Arachis duranensis (Wild peanut). protein EDS1 | Arachis duranensis |
| maize-b4fpy6 | Zea mays (Maize). Protein EDS1 | Zea mays |
| 9rosa-a0a5n5i4t3 | Pyrus ussuriensis x Pyrus communis. Senescence-associated carboxylesterase 101-like | Pyrus ussuriensis x Pyrus communis |
| daucs-a0a165a8x0 | Daucus carota subsp. sativus (Carrot). Uncharacterized protein | Daucus carota subsp. sativus |
| arahy-a0a444z2t3 | Arachis hypogaea (Peanut). Uncharacterized protein | Arachis hypogaea |
| panmi-a0a3l6qv47 | Panicum miliaceum (Proso millet) (Broomcorn millet). Protein EDS1L-like | Panicum miliaceum |
| vitvi-d7si01 | Vitis vinifera (Grape). Uncharacterized protein | Vitis vinifera |
| vitvi-d7si06 | Vitis vinifera (Grape). Uncharacterized protein | Vitis vinifera |
| maldo-a0a498jsy6 | Malus domestica (Apple) (Pyrus malus). Uncharacterized protein | Malus domestica |
| malba-a0a540lr05 | Malus baccata (Siberian crab apple) (Pyrus baccata). Uncharacterized protein | Malus baccata |
| daucs-a0a165a8w1 | Daucus carota subsp. sativus (Carrot). Uncharacterized protein | Daucus carota subsp. sativus |
| pruav-a0a6p5tfl8 | Prunus avium (Cherry) (Cerasus avium). protein EDS1L-like | Prunus avium |
| pruar-a0a6j5xjr9 | Prunus armeniaca (Apricot) (Armeniaca vulgaris). Uncharacterized protein | Prunus armeniaca |
| Gene_locus_frgt | Name | Species |
|---|---|---|
| braol-q704s9 | Brassica oleracea (Cauliflower) eds1-like protein (fragment) | Brassica oleracea |
| braol-q704t0 | Brassica oleracea (Cauliflower) eds1-like protein (fragment) | Brassica oleracea |
| medsa-q45nk3 | Medicago sativa (Alfalfa) hypothetical protein (fragment) | Medicago sativa |
| braol-a0a0d3a926 | Brassica oleracea var. oleracea. Uncharacterized protein | Brassica oleracea var. oleracea |
| lacsi-a0a6s7ljk5 | Lactuca saligna (Willowleaf lettuce). Uncharacterized protein | Lactuca saligna |
| 9eric-a0a7j0dca3 | Actinidia rufa. Uncharacterized protein | Actinidia rufa |
| actcc-a0a2r6pdz1 | Actinidia chinensis var. chinensis (Chinese soft-hair kiwi). Protein EDS1L like | Actinidia chinensis var. chinensis |
| 9rosi-a0a5n6rr66 | Carpinus fangiana. Uncharacterized protein | Carpinus fangiana |
| eucgr-a0a059a697 | Eucalyptus grandis (Flooded gum). EDS1_EP domain-containing protein | Eucalyptus grandis |
| eucgr-a0a059a6h5 | Eucalyptus grandis (Flooded gum). Uncharacterized protein | Eucalyptus grandis |
| cyncs-a0a118jyu2 | Cynara cardunculus var. scolymus (Globe artichoke) (Cynara scolymus). Lipase, class 3 | Cynara cardunculus var. scolymus |
| 9rosi-a0a5n5kpc2 | Salix brachista. Uncharacterized protein | Salix brachista |
| quelo-a0a7n2mnv5 | Quercus lobata (Valley oak). Uncharacterized protein | Quercus lobata |
| 9faba-a0a392m0i0 | Trifolium medium. Senescence-associated carboxylesterase 101-like | Trifolium medium |
| hibsy-a0a6a2zn23 | Hibiscus syriacus (Rose of Sharon). Zinc finger CCCH domain-containing protein 5-like isoform X1 | Hibiscus syriacus |
| Substrate | Chemical Nomenclature | Proteins |
|---|---|---|
| pRib-AMP | [5-(6-aminopurin-9-yl)-4-[3,4-dihydroxy-5-(phosphonooxymethyl)oxolan-2-yl]oxy-3-hydroxyoxolan-2-yl]methyl dihydrogen phosphate | arath-eds1 arath-PAD4 |
| ADP-ribose | [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-3,4,5-trihydroxyoxolan-2-yl]methyl hydrogen phosphate | arath-eds1 arath-PAD4 |
| pRib-ADP | arath-eds1 arath-PAD4 |
References (16)
| Title : METACASPASE8 (MC8) Is a Crucial Protein in the LSD1-Dependent Cell Death Pathway in Response to Ultraviolet Stress - Bernacki_2024_Int.J.Mol.Sci_25_3195 |
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| Abstract : |
| PubMedSearch : Bernacki_2024_Int.J.Mol.Sci_25_3195 |
| PubMedID: 38542169 |
| Title : The NLR immune receptor ADR1 and lipase-like proteins EDS1 and PAD4 mediate stomatal immunity in Nicotiana benthamiana and Arabidopsis - Wang_2023_Plant.Cell__ |
| Author(s) : Wang H , Song S , Gao S , Yu Q , Zhang H , Cui X , Fan J , Xin X , Liu Y , Staskawicz B , Qi T |
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| Title : Plant immune signaling network mediated by helper NLRs - Gong_2023_Curr.Opin.Plant.Biol_73_102354 |
| Author(s) : Gong Y , Tian L , Kontos I , Li J , Li X |
| Ref : Curr Opin Plant Biol , 73 :102354 , 2023 |
| Abstract : |
| PubMedSearch : Gong_2023_Curr.Opin.Plant.Biol_73_102354 |
| PubMedID: 37003229 |
| Title : Cavity surface residues of PAD4 and SAG101 contribute to EDS1 dimer signaling specificity in plant immunity - Dongus_2022_Plant.J__ |
| Author(s) : Dongus JA , Bhandari DD , Penner E , Lapin D , Stolze SC , Harzen A , Patel M , Archer L , Dijkgraaf L , Shah J , Nakagami H , Parker JE |
| Ref : Plant J , : , 2022 |
| Abstract : |
| PubMedSearch : Dongus_2022_Plant.J__ |
| PubMedID: 35324052 |
| Gene_locus related to this paper: arath-At5g14930 , arath-eds1 , arath-PAD4 |
| Title : Pathogen effector recognition-dependent association of NRG1 with EDS1 and SAG101 in TNL receptor immunity - Sun_2021_Nat.Commun_12_3335 |
| Author(s) : Sun X , Lapin D , Feehan JM , Stolze SC , Kramer K , Dongus JA , Rzemieniewski J , Blanvillain-Baufume S , Harzen A , Bautor J , Derbyshire P , Menke FLH , Finkemeier I , Nakagami H , Jones JDG , Parker JE |
| Ref : Nat Commun , 12 :3335 , 2021 |
| Abstract : |
| PubMedSearch : Sun_2021_Nat.Commun_12_3335 |
| PubMedID: 34099661 |
| Gene_locus related to this paper: arath-At5g14930 , arath-eds1 , arath-PAD4 |
| Title : Origins and Immunity Networking Functions of EDS1 Family Proteins - Lapin_2020_Annu.Rev.Phytopathol__ |
| Author(s) : Lapin D , Bhandari DD , Parker JE |
| Ref : Annu Rev Phytopathol , : , 2020 |
| Abstract : |
| PubMedSearch : Lapin_2020_Annu.Rev.Phytopathol__ |
| PubMedID: 32396762 |
| Title : A Coevolved EDS1-SAG101-NRG1 Module Mediates Cell Death Signaling by TIR-Domain Immune Receptors - Lapin_2019_Plant.Cell_31_2430 |
| Author(s) : Lapin D , Kovacova V , Sun X , Dongus JA , Bhandari D , von Born P , Bautor J , Guarneri N , Rzemieniewski J , Stuttmann J , Beyer A , Parker JE |
| Ref : Plant Cell , 31 :2430 , 2019 |
| Abstract : |
| PubMedSearch : Lapin_2019_Plant.Cell_31_2430 |
| PubMedID: 31311833 |
| Gene_locus related to this paper: arath-At5g14930 , arath-eds1 , arath-PAD4 |
| Title : Comparative genomic analysis of the Lipase3 gene family in five plant species reveals distinct evolutionary origins - Wang_2018_Genetica_146_179 |
| Author(s) : Wang D , Zhang L , Hu J , Gao D , Liu X , Sha Y |
| Ref : Genetica , 146 :179 , 2018 |
| Abstract : |
| PubMedSearch : Wang_2018_Genetica_146_179 |
| PubMedID: 29468429 |
| Title : Rice OsPAD4 functions differently from Arabidopsis AtPAD4 in host-pathogen interactions - Ke_2014_Plant.J_78_619 |
| Author(s) : Ke Y , Liu H , Li X , Xiao J , Wang S |
| Ref : Plant J , 78 :619 , 2014 |
| Abstract : |
| PubMedSearch : Ke_2014_Plant.J_78_619 |
| PubMedID: 24617729 |
| Gene_locus related to this paper: orysa-q53lh1 |
| Title : In silico study of interaction between rice proteins enhanced disease susceptibility 1 and phytoalexin deficient 4, the regulators of salicylic acid signalling pathway - Singh_2012_J.Biosci_37_563 |
| Author(s) : Singh I , Shah K |
| Ref : J Biosci , 37 :563 , 2012 |
| Abstract : |
| PubMedSearch : Singh_2012_J.Biosci_37_563 |
| PubMedID: 22750992 |
| Gene_locus related to this paper: orysa-q6h415 , orysa-q53lh1 |
| Title : EDS1 contributes to nonhost resistance of Arabidopsis thaliana against Erwinia amylovora - Moreau_2012_Mol.Plant.Microbe.Interact_25_421 |
| Author(s) : Moreau M , Degrave A , Vedel R , Bitton F , Patrit O , Renou JP , Barny MA , Fagard M |
| Ref : Mol Plant Microbe Interact , 25 :421 , 2012 |
| Abstract : |
| PubMedSearch : Moreau_2012_Mol.Plant.Microbe.Interact_25_421 |
| PubMedID: 22316300 |
| Gene_locus related to this paper: arath-eds1 |
| Title : Crystallization and preliminary crystallographic analysis of Arabidopsis thaliana EDS1, a key component of plant immunity, in complex with its signalling partner SAG101 - Wagner_2011_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_67_245 |
| Author(s) : Wagner S , Rietz S , Parker JE , Niefind K |
| Ref : Acta Crystallographica Sect F Struct Biol Cryst Commun , 67 :245 , 2011 |
| Abstract : |
| PubMedSearch : Wagner_2011_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_67_245 |
| PubMedID: 21301097 |
| Gene_locus related to this paper: arath-At5g14930 , arath-eds1 , arath-PAD4 |
| Title : A functional EDS1 ortholog is differentially regulated in powdery mildew resistant and susceptible grapevines and complements an Arabidopsis eds1 mutant - Gao_2010_Planta_231_1037 |
| Author(s) : Gao F , Shu X , Ali MB , Howard S , Li N , Winterhagen P , Qiu W , Gassmann W |
| Ref : Planta , 231 :1037 , 2010 |
| Abstract : |
| PubMedSearch : Gao_2010_Planta_231_1037 |
| PubMedID: 20145949 |
| Gene_locus related to this paper: arath-eds1 |
| Title : Balanced nuclear and cytoplasmic activities of EDS1 are required for a complete plant innate immune response - Garcia_2010_PLoS.Pathog_6_e1000970 |
| Author(s) : Garcia AV , Blanvillain-Baufume S , Huibers RP , Wiermer M , Li G , Gobbato E , Rietz S , Parker JE |
| Ref : PLoS Pathog , 6 :e1000970 , 2010 |
| Abstract : |
| PubMedSearch : Garcia_2010_PLoS.Pathog_6_e1000970 |
| PubMedID: 20617163 |
| Gene_locus related to this paper: arath-eds1 |
| Title : Plant immunity: the EDS1 regulatory node - Wiermer_2005_Curr.Opin.Plant.Biol_8_383 |
| Author(s) : Wiermer M , Feys BJ , Parker JE |
| Ref : Curr Opin Plant Biol , 8 :383 , 2005 |
| Abstract : |
| PubMedSearch : Wiermer_2005_Curr.Opin.Plant.Biol_8_383 |
| PubMedID: 15939664 |
| Gene_locus related to this paper: arath-eds1 , arath-PAD4 |
| Title : EDS1, an essential component of R gene-mediated disease resistance in Arabidopsis has homology to eukaryotic lipases - Falk_1999_Proc.Natl.Acad.Sci.U.S.A_96_3292 |
| Author(s) : Falk A , Feys BJ , Frost LN , Jones JDG , Daniels MJ , Parker JE |
| Ref : Proceedings of the National Academy of Sciences of the United States of America , 96 :3292 , 1999 |
| Abstract : |
| PubMedSearch : Falk_1999_Proc.Natl.Acad.Sci.U.S.A_96_3292 |
| PubMedID: 10077677 |
| Gene_locus related to this paper: arath-eds1 |