Gene_Locus Report

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Gene_locus Report for: macmu-f7buk8

Macaca mulatta (Rhesus macaque) Uncharacterized protein

Comment
only n-term Pfam A COesterase 4 544


Relationship
Family|Cholesterol_esterase
Block| C
Position in NCBI Life Tree|Macaca mulatta
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Metazoa: N E > Eumetazoa: N E > Bilateria: N E > Deuterostomia: N E > Chordata: N E > Craniata: N E > Vertebrata: N E > Gnathostomata: N E > Teleostomi: N E > Euteleostomi: N E > Sarcopterygii: N E > Dipnotetrapodomorpha: N E > Tetrapoda: N E > Amniota: N E > Mammalia: N E > Theria: N E > Eutheria: N E > Boreoeutheria: N E > Euarchontoglires: N E > Primates: N E > Haplorrhini: N E > Simiiformes: N E > Catarrhini: N E > Cercopithecoidea: N E > Cercopithecidae: N E > Cercopithecinae: N E > Macaca: N E > Macaca mulatta: N E


Molecular evidence
Database
No mutation
No structure
No kinetic





No Substrate
No inhibitor
1 Genbank : CM001267
2 UniProt : F7A7S8, G7NFG7
2 UniProt : F7A7S8, G7NFG7
2 Interpro : F7A7S8, G7NFG7
2 Prodom : F7A7S8, G7NFG7
2 Pfam : F7A7S8, G7NFG7
2 PIRSF : F7A7S8, G7NFG7
2 SUPERFAM : F7A7S8, G7NFG7
Sequence
Graphical view for this peptide sequence: macmu-f7buk8
Colored MSA for Cholesterol_esterase (raw)
HMGRLQLVVLGLACCWAVASAAKLGPVYTEGGFVEGVNKKLGLLGDSVDI
FKGIPFAAPTKALENPQPHPGWQGTLKAKSFKKRCLQATITQDSTYGDED
CLYLNIWVPQDRKQVSRDLPVMIWIYGGAFLMGSGHGANFLSNYLYDGEE
IATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIA
AFGGDPNNLTLFGESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWVI
QKNPLFWAKKVAEKVGCPVDDTARMAKCLKVTDPRALTLAYKMPLAGMEY
PMLYYLGFIPVIDGDFIPDDPINLYANAADIDYIAGINNMDGHLFASIDM
PAINKNNKEVTEEDFYKLVSGLTMTKGLRGAKTTFDVYTESWAQDPSQEN
KKKTVVDFETDILFLVPTEIALAQHRANAKSAKTYSYLFSHPSRMPVYPK
WMGADHADDIQYLLAEPQARARVQPVSCVRVQSRPSAPWDLFSLCRDPNM
GHSAVPTQWEPYTSENGSYLEITKKMDGSSVKRGLRTNFLRYWTLTYVAL
PTVTD
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

HMGRLQLVVLGLACCWAVASAAKLGPVYTEGGFVEGVNKKLGLLGDSVDI
FKGIPFAAPTKALENPQPHPGWQGTLKAKSFKKRCLQATITQDSTYGDED
CLYLNIWVPQDRKQVSRDLPVMIWIYGGAFLMGSGHGANFLSNYLYDGEE
IATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIA
AFGGDPNNLTLFGESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWVI
QKNPLFWAKKVAEKVGCPVDDTARMAKCLKVTDPRALTLAYKMPLAGMEY
PMLYYLGFIPVIDGDFIPDDPINLYANAADIDYIAGINNMDGHLFASIDM
PAINKNNKEVTEEDFYKLVSGLTMTKGLRGAKTTFDVYTESWAQDPSQEN
KKKTVVDFETDILFLVPTEIALAQHRANAKSAKTYSYLFSHPSRMPVYPK
WMGADHADDIQYLLAEPQARARVQPVSCVRVQSRPSAPWDLFSLCRDPNM
GHSAVPTQWEPYTSENGSYLEITKKMDGSSVKRGLRTNFLRYWTLTYVAL
PTVTD


References
    Title: Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques
    Yan G, Zhang G, Fang X, Zhang Y, Li C, Ling F, Cooper DN, Li Q, Li Y and Wang X <32 more author(s)>
    Ref: Nat Biotechnol, 29:1019, 2011 : PubMed

            

    Title: Evolutionary and biomedical insights from the rhesus macaque genome
    Gibbs RA, Rogers J, Katze MG, Bumgarner R, Weinstock GM, Mardis ER, Remington KA, Strausberg RL, Venter JC and Zwieg AS <166 more author(s)>
    Ref: Science, 316:222, 2007 : PubMed

            


Other Papers


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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