| Title : Synthesis of Tacrine\/Amiridine Conjugates with Aminomethylidene Derivatives of Trifluoroacetoacetic Ester and their Biological Potential for the Therapy of Alzheimer's Disease - Grishchenko_2025_ChemMedChem__e202500723 |
| Author(s) : Grishchenko MV , Makhaeva GF , Burgart YV , Kovaleva NV , Boltneva NP , Skornyakova TS , Rudakova EV , Astakhova TY , Timokhina EN , Pronkin PG , Shchegolkov EV , Saloutin V , Charushin VN |
| Ref : ChemMedChem , :e202500723 , 2025 |
| Abstract : |
| PubMedSearch : Grishchenko_2025_ChemMedChem__e202500723 |
| PubMedID: 41047157 |
| Title : Synthesis, biological evaluation, and in silico studies of pyridoxal-amiridine hybrids as multitargeting anti-Alzheimer's disease agents - Makhaeva_2025_Eur.J.Med.Chem_303_118397 |
| Author(s) : Makhaeva GF , Grishchenko MV , Rudakova EV , Kovaleva NV , Boltneva NP , Skornyakova TS , Khudina OG , Shchegolkov EV , Zhilina EF , Astakhova TY , Pronkin PG , Timokhina EN , Lapshina MA , Dubrovskaya ES , Radchenko EV , Palyulin VA , Burgart YV , Saloutin VI , Charushin VN , Richardson RJ |
| Ref : Eur Journal of Medicinal Chemistry , 303 :118397 , 2025 |
| Abstract : |
| PubMedSearch : Makhaeva_2025_Eur.J.Med.Chem_303_118397 |
| PubMedID: 41338134 |
| Title : Conjugates of anticholinesterase drugs ipidacrine and tacrine with thiouracils: synthesis and biological properties - Grishchenko_2025_Russ.Chem.Bull_73_3399 |
| Author(s) : Grishchenko MV , Khudina OG , Makhaeva GF , Burgart YV , Kovaleva NV , Rudakova EV , Boltneva NP , Ulitko MV , Saloutin VI , Charushin VN |
| Ref : Russ Chem Bull , 73 :3399 , 2025 |
| Abstract : |
| PubMedSearch : Grishchenko_2025_Russ.Chem.Bull_73_3399 |
| PubMedID: |
| Title : Conjugates of amiridine and salicylic derivatives as promising multifunctional CNS agents for potential treatment of Alzheimer's disease - Makhaeva_2025_Arch.Pharm.(Weinheim)_358_e2400819 |
| Author(s) : Makhaeva GF , Grishchenko MV , Kovaleva NV , Boltneva NP , Rudakova EV , Astakhova TY , Timokhina EN , Pronkin PG , Lushchekina SV , Khudina OG , Zhilina EF , Shchegolkov EV , Lapshina MA , Dubrovskaya ES , Radchenko EV , Palyulin VA , Burgart YV , Saloutin VI , Charushin VN , Richardson RJ |
| Ref : Arch Pharm (Weinheim) , 358 :e2400819 , 2025 |
| Abstract : |
| PubMedSearch : Makhaeva_2025_Arch.Pharm.(Weinheim)_358_e2400819 |
| PubMedID: 39686878 |
| Title : 1-Azinyl-1'-Alkenylferrocenes with Anticholinesterase, Antioxidant, and Antiaggregating Activities as Multifunctional Agents for Potential Treatment of Alzheimer's Disease - Makhaeva_2025_Pharmaceuticals.(Basel)_18_ |
| Author(s) : Makhaeva GF , Utepova IA , Rudakova EV , Kovaleva NV , Boltneva NP , Zyryanova EY , Musikhina AA , Lazarev VF , Vladimirova SA , Guzhova IV , Ganebnykh IN , Astakhova TY , Timokhina EN , Chupakhin ON , Charushin VN , Richardson RJ |
| Ref : Pharmaceuticals (Basel) , 18 : , 2025 |
| Abstract : |
| PubMedSearch : Makhaeva_2025_Pharmaceuticals.(Basel)_18_ |
| PubMedID: 41471351 |
| Title : 2-Arylhydrazinylidene-3-oxo-3-polyfluoroalkylpropanoic acids as selective and effective carboxylesterase inhibitors with powerful antioxidant potential - Burgart_2024_Bioorg.Med.Chem_115_117938 |
| Author(s) : Burgart YV , Makhaeva GF , Khudina OG , Krasnykh OP , Kovaleva NV , Elkina NA , Boltneva NP , Rudakova EV , Lushchekina SV , Shchegolkov EV , Triandafilova GA , Malysheva KO , Serebryakova OG , Borisevich SS , Ilyina MG , Zhilina EF , Saloutin VI , Charushin VN , Richardson RJ |
| Ref : Bioorganic & Medicinal Chemistry , 115 :117938 , 2024 |
| Abstract : |
| PubMedSearch : Burgart_2024_Bioorg.Med.Chem_115_117938 |
| PubMedID: 39504592 |
| Title : Derivatives of 9-phosphorylated acridine as butyrylcholinesterase inhibitors with antioxidant activity and the ability to inhibit beta-amyloid self-aggregation: potential therapeutic agents for Alzheimer's disease - Makhaeva_2023_Front.Pharmacol_14_1219980 |
| Author(s) : Makhaeva GF , Kovaleva NV , Rudakova EV , Boltneva NP , Lushchekina SV , Astakhova TY , Timokhina EN , Serebryakova OG , Shchepochkin AV , Averkov MA , Utepova IA , Demina NS , Radchenko EV , Palyulin VA , Fisenko VP , Bachurin SO , Chupakhin ON , Charushin VN , Richardson RJ |
| Ref : Front Pharmacol , 14 :1219980 , 2023 |
| Abstract : |
| PubMedSearch : Makhaeva_2023_Front.Pharmacol_14_1219980 |
| PubMedID: 37654616 |
| Title : Conjugates of amiridine and thiouracil derivatives as effective inhibitors of butyrylcholinesterase with the potential to block beta-amyloid aggregation - Khudina_2023_Arch.Pharm.(Weinheim)__e2300447 |
| Author(s) : Khudina OG , Grishchenko MV , Makhaeva GF , Kovaleva NV , Boltneva NP , Rudakova EV , Lushchekina SV , Shchegolkov EV , Borisevich SS , Burgart YV , Saloutin VI , Charushin VN |
| Ref : Arch Pharm (Weinheim) , :e2300447 , 2023 |
| Abstract : |
| PubMedSearch : Khudina_2023_Arch.Pharm.(Weinheim)__e2300447 |
| PubMedID: 38072670 |
| Title : 9-Substituted acridine derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors possessing antioxidant activity for Alzheimer's disease treatment - Makhaeva_2017_Bioorg.Med.Chem_25_5981 |
| Author(s) : Makhaeva GF , Lushchekina SV , Boltneva NP , Serebryakova OG , Rudakova EV , Ustyugov AA , Bachurin SO , Shchepochkin AV , Chupakhin ON , Charushin VN , Richardson RJ |
| Ref : Bioorganic & Medicinal Chemistry , 25 :5981 , 2017 |
| Abstract : |
| PubMedSearch : Makhaeva_2017_Bioorg.Med.Chem_25_5981 |
| PubMedID: 28986116 |