| Title : Conjugates of anticholinesterase drugs ipidacrine and tacrine with thiouracils: synthesis and biological properties - Grishchenko_2025_Russ.Chem.Bull_73_3399 |
| Author(s) : Grishchenko MV , Khudina OG , Makhaeva GF , Burgart YV , Kovaleva NV , Rudakova EV , Boltneva NP , Ulitko MV , Saloutin VI , Charushin VN |
| Ref : Russ Chem Bull , 73 :3399 , 2025 |
| Abstract : |
| PubMedSearch : Grishchenko_2025_Russ.Chem.Bull_73_3399 |
| PubMedID: |
| Title : Conjugates of amiridine and salicylic derivatives as promising multifunctional CNS agents for potential treatment of Alzheimer's disease - Makhaeva_2025_Arch.Pharm.(Weinheim)_358_e2400819 |
| Author(s) : Makhaeva GF , Grishchenko MV , Kovaleva NV , Boltneva NP , Rudakova EV , Astakhova TY , Timokhina EN , Pronkin PG , Lushchekina SV , Khudina OG , Zhilina EF , Shchegolkov EV , Lapshina MA , Dubrovskaya ES , Radchenko EV , Palyulin VA , Burgart YV , Saloutin VI , Charushin VN , Richardson RJ |
| Ref : Arch Pharm (Weinheim) , 358 :e2400819 , 2025 |
| Abstract : |
| PubMedSearch : Makhaeva_2025_Arch.Pharm.(Weinheim)_358_e2400819 |
| PubMedID: 39686878 |
| Title : 2-Arylhydrazinylidene-3-oxo-3-polyfluoroalkylpropanoic acids as selective and effective carboxylesterase inhibitors with powerful antioxidant potential - Burgart_2024_Bioorg.Med.Chem_115_117938 |
| Author(s) : Burgart YV , Makhaeva GF , Khudina OG , Krasnykh OP , Kovaleva NV , Elkina NA , Boltneva NP , Rudakova EV , Lushchekina SV , Shchegolkov EV , Triandafilova GA , Malysheva KO , Serebryakova OG , Borisevich SS , Ilyina MG , Zhilina EF , Saloutin VI , Charushin VN , Richardson RJ |
| Ref : Bioorganic & Medicinal Chemistry , 115 :117938 , 2024 |
| Abstract : |
| PubMedSearch : Burgart_2024_Bioorg.Med.Chem_115_117938 |
| PubMedID: 39504592 |
| Title : Conjugates of Tacrine and Salicylic Acid Derivatives as New Promising Multitarget Agents for Alzheimer's Disease - Makhaeva_2023_Int.J.Mol.Sci_24_2285 |
| Author(s) : Makhaeva GF , Kovaleva NV , Rudakova EV , Boltneva NP , Grishchenko MV , Lushchekina SV , Astakhova TY , Serebryakova OG , Timokhina EN , Zhilina EF , Shchegolkov EV , Ulitko MV , Radchenko EV , Palyulin VA , Burgart YV , Saloutin VI , Bachurin SO , Richardson RJ |
| Ref : Int J Mol Sci , 24 :2285 , 2023 |
| Abstract : |
| PubMedSearch : Makhaeva_2023_Int.J.Mol.Sci_24_2285 |
| PubMedID: 36768608 |
| Title : Conjugates of amiridine and thiouracil derivatives as effective inhibitors of butyrylcholinesterase with the potential to block beta-amyloid aggregation - Khudina_2023_Arch.Pharm.(Weinheim)__e2300447 |
| Author(s) : Khudina OG , Grishchenko MV , Makhaeva GF , Kovaleva NV , Boltneva NP , Rudakova EV , Lushchekina SV , Shchegolkov EV , Borisevich SS , Burgart YV , Saloutin VI , Charushin VN |
| Ref : Arch Pharm (Weinheim) , :e2300447 , 2023 |
| Abstract : |
| PubMedSearch : Khudina_2023_Arch.Pharm.(Weinheim)__e2300447 |
| PubMedID: 38072670 |
| Title : New Multifunctional Agents for Potential Alzheimer's Disease Treatment Based on Tacrine Conjugates with 2-Arylhydrazinylidene-1,3-Diketones - Elkina_2022_Biomolecules_12_ |
| Author(s) : Elkina NA , Grishchenko MV , Shchegolkov EV , Makhaeva GF , Kovaleva NV , Rudakova EV , Boltneva NP , Lushchekina SV , Astakhova TY , Radchenko EV , Palyulin VA , Zhilina EF , Perminova AN , Lapshin LS , Burgart YV , Saloutin VI , Richardson RJ |
| Ref : Biomolecules , 12 : , 2022 |
| Abstract : |
| PubMedSearch : Elkina_2022_Biomolecules_12_ |
| PubMedID: 36358901 |
| Title : Conjugates of Tacrine with Salicylamide as Promising Multitarget Agents for Alzheimer's Disease - Grishchenko_2022_ChemMedChem__e202200080 |
| Author(s) : Grishchenko MV , Makhaeva GF , Burgart YV , Rudakova EV , Boltneva NP , Kovaleva NV , Serebryakova OG , Lushchekina SV , Astakhova TY , Zhilina EF , Shchegolkov EV , Richardson RJ , Saloutin VI |
| Ref : ChemMedChem , :e202200080 , 2022 |
| Abstract : |
| PubMedSearch : Grishchenko_2022_ChemMedChem__e202200080 |
| PubMedID: 35322571 |
| Title : Powerful Potential of Polyfluoroalkyl-Containing 4-Arylhydrazinylidenepyrazol-3-ones for Pharmaceuticals - Burgart_2022_Molecules_28_ |
| Author(s) : Burgart YV , Elkina NA , Shchegolkov EV , Krasnykh OP , Makhaeva GF , Triandafilova GA , Solodnikov SY , Boltneva NP , Rudakova EV , Kovaleva NV , Serebryakova OG , Ulitko MV , Borisevich SS , Gerasimova NA , Evstigneeva NP , Kozlov SA , Korolkova YV , Minin AS , Belousova AV , Mozhaitsev ES , Klabukov AM , Saloutin VI |
| Ref : Molecules , 28 : , 2022 |
| Abstract : |
| PubMedSearch : Burgart_2022_Molecules_28_ |
| PubMedID: 36615256 |
| Title : Novel potent bifunctional carboxylesterase inhibitors based on a polyfluoroalkyl-2-imino-1,3-dione scaffold - Makhaeva_2021_Eur.J.Med.Chem_218_113385 |
| Author(s) : Makhaeva GF , Lushchekina SV , Boltneva NP , Serebryakova OG , Kovaleva NV , Rudakova EV , Elkina NA , Shchegolkov EV , Burgart YV , Stupina TS , Terentiev AA , Radchenko EV , Palyulin VA , Saloutin VI , Bachurin SO , Richardson RJ |
| Ref : Eur Journal of Medicinal Chemistry , 218 :113385 , 2021 |
| Abstract : |
| PubMedSearch : Makhaeva_2021_Eur.J.Med.Chem_218_113385 |
| PubMedID: 33831780 |
| Title : Synthesis, molecular docking, and biological evaluation of 3-oxo-2-tolylhydrazinylidene-4,4,4-trifluorobutanoates bearing higher and natural alcohol moieties as new selective carboxylesterase inhibitors - Makhaeva_2019_Bioorg.Chem_91_103097 |
| Author(s) : Makhaeva GF , Elkina NA , Shchegolkov EV , Boltneva NP , Lushchekina SV , Serebryakova OG , Rudakova EV , Kovaleva NV , Radchenko EV , Palyulin VA , Burgart YV , Saloutin VI , Bachurin SO , Richardson RJ |
| Ref : Bioorg Chem , 91 :103097 , 2019 |
| Abstract : |
| PubMedSearch : Makhaeva_2019_Bioorg.Chem_91_103097 |
| PubMedID: 31323527 |
| Title : Synthesis of 2-arylhydrazinylidene-3-oxo-4,4,4-trifluorobutanoic acids as new selective carboxylesterase inhibitors and radical scavengers - Khudina_2019_Bioorg.Med.Chem.Lett__126716 |
| Author(s) : Khudina OG , Makhaeva GF , Elkina NA , Boltneva NP , Serebryakova OG , Shchegolkov EV , Rudakova EV , Lushchekina SV , Burgart YV , Bachurin SO , Richardson RJ , Saloutin VI |
| Ref : Bioorganic & Medicinal Chemistry Lett , :126716 , 2019 |
| Abstract : |
| PubMedSearch : Khudina_2019_Bioorg.Med.Chem.Lett__126716 |
| PubMedID: 31640885 |
| Title : Cholinesterase and carboxylesterase inhibitors as pharmacological agents - Makhaeva_2019_Russ.Chem.Bull_68_967 |
| Author(s) : Makhaeva GF , Rudakova EV , Kovaleva NV , Lushchekina SV , Boltneva NP , Proshin AN , Shchegolkov EV , Burgart YV , Saloutin VI |
| Ref : Russ Chem Bull , 68 :967 , 2019 |
| Abstract : |
| PubMedSearch : Makhaeva_2019_Russ.Chem.Bull_68_967 |
| PubMedID: |
| Title : Synthesis, molecular docking, and biological activity of polyfluoroalkyl dihydroazolo[5,1-c][1,2,4]triazines as selective carboxylesterase inhibitors - Shchegol'kov_2017_Bioorg.Med.Chem_25_3997 |
| Author(s) : Shchegol'kov EV , Makhaeva GF , Boltneva NP , Lushchekina SV , Serebryakova OG , Rudakova EV , Kovaleva NV , Burgart YV , Saloutin VI , Chupakhin ON , Bachurin SO , Richardson RJ |
| Ref : Bioorganic & Medicinal Chemistry , 25 :3997 , 2017 |
| Abstract : |
| PubMedSearch : Shchegol'kov_2017_Bioorg.Med.Chem_25_3997 |
| PubMedID: 28578994 |
| Title : Alkyl 2-arylhydrazinylidene-3-oxo-3-polyfluoroalkylpropionates as new effective and selective inhibitors of carboxylesterase - Boltneva_2015_Dokl.Biochem.Biophys_465_381 |
| Author(s) : Boltneva NP , Makhaeva GF , Kovaleva NV , Lushchekina SV , Burgart YV , Shchegol'kov EV , Saloutin VI , Chupakhin ON |
| Ref : Dokl Biochem Biophys , 465 :381 , 2015 |
| Abstract : |
| PubMedSearch : Boltneva_2015_Dokl.Biochem.Biophys_465_381 |
| PubMedID: 26728730 |