Palyulin VA

References (16)

Title : Combining Experimental and Computational Methods to Produce Conjugates of Anticholinesterase and Antioxidant Pharmacophores with Linker Chemistries Affecting Biological Activities Related to Treatment of Alzheimer's Disease - Makhaeva_2024_Molecules_29_321
Author(s) : Makhaeva GF , Kovaleva NV , Rudakova EV , Boltneva NP , Lushchekina SV , Astakhova TY , Timokhina EN , Serkov IV , Proshin AN , Soldatova YV , Poletaeva DA , Faingold, II , Mumyatova VA , Terentiev AA , Radchenko EV , Palyulin VA , Bachurin SO , Richardson RJ
Ref : Molecules , 29 :321 , 2024
Abstract :
PubMedSearch : Makhaeva_2024_Molecules_29_321
PubMedID: 38257233

Title : Derivatives of 9-phosphorylated acridine as butyrylcholinesterase inhibitors with antioxidant activity and the ability to inhibit beta-amyloid self-aggregation: potential therapeutic agents for Alzheimer's disease - Makhaeva_2023_Front.Pharmacol_14_1219980
Author(s) : Makhaeva GF , Kovaleva NV , Rudakova EV , Boltneva NP , Lushchekina SV , Astakhova TY , Timokhina EN , Serebryakova OG , Shchepochkin AV , Averkov MA , Utepova IA , Demina NS , Radchenko EV , Palyulin VA , Fisenko VP , Bachurin SO , Chupakhin ON , Charushin VN , Richardson RJ
Ref : Front Pharmacol , 14 :1219980 , 2023
Abstract :
PubMedSearch : Makhaeva_2023_Front.Pharmacol_14_1219980
PubMedID: 37654616

Title : Conjugates of Tacrine and Salicylic Acid Derivatives as New Promising Multitarget Agents for Alzheimer's Disease - Makhaeva_2023_Int.J.Mol.Sci_24_2285
Author(s) : Makhaeva GF , Kovaleva NV , Rudakova EV , Boltneva NP , Grishchenko MV , Lushchekina SV , Astakhova TY , Serebryakova OG , Timokhina EN , Zhilina EF , Shchegolkov EV , Ulitko MV , Radchenko EV , Palyulin VA , Burgart YV , Saloutin VI , Bachurin SO , Richardson RJ
Ref : Int J Mol Sci , 24 :2285 , 2023
Abstract :
PubMedSearch : Makhaeva_2023_Int.J.Mol.Sci_24_2285
PubMedID: 36768608

Title : New Multifunctional Agents for Potential Alzheimer's Disease Treatment Based on Tacrine Conjugates with 2-Arylhydrazinylidene-1,3-Diketones - Elkina_2022_Biomolecules_12_
Author(s) : Elkina NA , Grishchenko MV , Shchegolkov EV , Makhaeva GF , Kovaleva NV , Rudakova EV , Boltneva NP , Lushchekina SV , Astakhova TY , Radchenko EV , Palyulin VA , Zhilina EF , Perminova AN , Lapshin LS , Burgart YV , Saloutin VI , Richardson RJ
Ref : Biomolecules , 12 : , 2022
Abstract :
PubMedSearch : Elkina_2022_Biomolecules_12_
PubMedID: 36358901

Title : Bis-Amiridines as Acetylcholinesterase and Butyrylcholinesterase Inhibitors: N-Functionalization Determines the Multitarget Anti-Alzheimer's Activity Profile - Makhaeva_2022_Molecules_27_
Author(s) : Makhaeva GF , Kovaleva NV , Boltneva NP , Rudakova EV , Lushchekina SV , Astakhova TY , Serkov IV , Proshin AN , Radchenko EV , Palyulin VA , Korabecny J , Soukup O , Bachurin SO , Richardson RJ
Ref : Molecules , 27 : , 2022
Abstract :
PubMedSearch : Makhaeva_2022_Molecules_27_
PubMedID: 35164325

Title : Amiridine-piperazine hybrids as cholinesterase inhibitors and potential multitarget agents for Alzheimer's disease treatment - Makhaeva_2021_Bioorg.Chem_112_104974
Author(s) : Makhaeva GF , Lushchekina SV , Kovaleva NV , Yu Astakhova T , Boltneva NP , Rudakova EV , Serebryakova OG , Proshin AN , Serkov IV , Trofimova TP , Tafeenko VA , Radchenko EV , Palyulin VA , Fisenko VP , Korabecny J , Soukup O , Richardson RJ
Ref : Bioorg Chem , 112 :104974 , 2021
Abstract :
PubMedSearch : Makhaeva_2021_Bioorg.Chem_112_104974
PubMedID: 34029971

Title : Novel potent bifunctional carboxylesterase inhibitors based on a polyfluoroalkyl-2-imino-1,3-dione scaffold - Makhaeva_2021_Eur.J.Med.Chem_218_113385
Author(s) : Makhaeva GF , Lushchekina SV , Boltneva NP , Serebryakova OG , Kovaleva NV , Rudakova EV , Elkina NA , Shchegolkov EV , Burgart YV , Stupina TS , Terentiev AA , Radchenko EV , Palyulin VA , Saloutin VI , Bachurin SO , Richardson RJ
Ref : Eur Journal of Medicinal Chemistry , 218 :113385 , 2021
Abstract :
PubMedSearch : Makhaeva_2021_Eur.J.Med.Chem_218_113385
PubMedID: 33831780

Title : New Multifunctional Agents Based on Conjugates of 4-Amino-2,3-polymethylenequinoline and Butylated Hydroxytoluene for Alzheimer's Disease Treatment - Makhaeva_2020_Molecules_25_5891
Author(s) : Makhaeva GF , Kovaleva NV , Rudakova EV , Boltneva NP , Lushchekina SV , Faingold, II , Poletaeva DA , Soldatova YV , Kotelnikova RA , Serkov IV , Ustinov AK , Proshin AN , Radchenko EV , Palyulin VA , Richardson RJ
Ref : Molecules , 25 :5891 , 2020
Abstract :
PubMedSearch : Makhaeva_2020_Molecules_25_5891
PubMedID: 33322783

Title : New Hybrids of 4-Amino-2,3-polymethylene-quinoline and p-Tolylsulfonamide as Dual Inhibitors of Acetyl- and Butyrylcholinesterase and Potential Multifunctional Agents for Alzheimer's Disease Treatment - Makhaeva_2020_Molecules_25_3915
Author(s) : Makhaeva GF , Kovaleva NV , Boltneva NP , Lushchekina SV , Astakhova TY , Rudakova EV , Proshin AN , Serkov IV , Radchenko EV , Palyulin VA , Bachurin SO , Richardson RJ
Ref : Molecules , 25 :3915 , 2020
Abstract :
PubMedSearch : Makhaeva_2020_Molecules_25_3915
PubMedID: 32867324

Title : Synthesis, molecular docking, and biological evaluation of 3-oxo-2-tolylhydrazinylidene-4,4,4-trifluorobutanoates bearing higher and natural alcohol moieties as new selective carboxylesterase inhibitors - Makhaeva_2019_Bioorg.Chem_91_103097
Author(s) : Makhaeva GF , Elkina NA , Shchegolkov EV , Boltneva NP , Lushchekina SV , Serebryakova OG , Rudakova EV , Kovaleva NV , Radchenko EV , Palyulin VA , Burgart YV , Saloutin VI , Bachurin SO , Richardson RJ
Ref : Bioorg Chem , 91 :103097 , 2019
Abstract :
PubMedSearch : Makhaeva_2019_Bioorg.Chem_91_103097
PubMedID: 31323527

Title : Organophosphorus compound esterase profiles as predictors of therapeutic and toxic effects - Makhaeva_2013_Chem.Biol.Interact_203_231
Author(s) : Makhaeva GF , Radchenko EV , Palyulin VA , Rudakova EV , Aksinenko AY , Sokolov VB , Zefirov NS , Richardson RJ
Ref : Chemico-Biological Interactions , 203 :231 , 2013
Abstract :
PubMedSearch : Makhaeva_2013_Chem.Biol.Interact_203_231
PubMedID: 23123251

Title : Combined QSAR studies of inhibitor properties of O-phosphorylated oximes toward serine esterases involved in neurotoxicity, drug metabolism and Alzheimer's disease - Makhaeva_2012_SAR.QSAR.Environ.Res_23_627
Author(s) : Makhaeva GF , Radchenko EV , Baskin II , Palyulin VA , Richardson RJ , Zefirov NS
Ref : SAR QSAR Environ Research , 23 :627 , 2012
Abstract :
PubMedSearch : Makhaeva_2012_SAR.QSAR.Environ.Res_23_627
PubMedID: 22587543

Title : Molecular design of O-phosphorylated oximes--selective inhibitors of butyrylcholinesterase -
Author(s) : Radchenko EV , Mel'nikov AA , Makhaeva GF , Palyulin VA , Zefirov NS
Ref : Dokl Biochem Biophys , 443 :91 , 2012
PubMedID: 22562633

Title : Kinetics and mechanism of inhibition of serine esterases by fluorinated aminophosphonates - Makhaeva_2010_Chem.Biol.Interact_187_177
Author(s) : Makhaeva GF , Aksinenko AY , Sokolov VB , Baskin, II , Palyulin VA , Zefirov NS , Hein ND , Kampf JW , Wijeyesakere SJ , Richardson RJ
Ref : Chemico-Biological Interactions , 187 :177 , 2010
Abstract :
PubMedSearch : Makhaeva_2010_Chem.Biol.Interact_187_177
PubMedID: 20035729

Title : Study of the structural determinants of acute and delayed neurotoxicity of O-phosphorylated oximes by molecular field topology analysis (MFTA) -
Author(s) : Radchenko EV , Makhaeva GF , Sokolov VB , Palyulin VA , Zefirov NS
Ref : Dokl Biochem Biophys , 429 :309 , 2009
PubMedID: 20101827

Title : Modeling of the relationships between the structure of O-phosphorylated oximes and their anticholinesterase activity and selectivity using molecular field topology analysis (MFTA) -
Author(s) : Radchenko EV , Makhaeva GF , Malygin VV , Sokolov VB , Palyulin VA , Zefirov NS
Ref : Dokl Biochem Biophys , 418 :47 , 2008
PubMedID: 18429606