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OPIDN-OP

General

organophosphorus compound inhibiting cholinesterases but also inducing delayed neurotoxicity (OPIDN) by inhibiting Neuropathy target esterase (NTE/PNPLA6 not an alpha/beta hydrolase)
Inhibitor Main targeted enzyme families Type Structure
S9B Organophosphate Cyclic OP NTE inhibitor OPIDN-OP Not AlphaBeta Hydrolase target Sulfur Compound Biotin derivative
Hexyl-dcp Organophosphate Not AlphaBeta Hydrolase target OPIDN-OP
O-hexyl-O-2,5-dichlorophenyl-phosphoramidate Organophosphate Not AlphaBeta Hydrolase target OPIDN-OP NTE inhibitor
Cyanofenphos ACHE Organophosphate NTE inhibitor Cyanide Not AlphaBeta Hydrolase target Sulfur Compound OPIDN-OP
DSF LYsophospholipase_carboxylesterase Acidic_Lipase Sulfur Compound Sulfonyl NTE inhibitor Not AlphaBeta Hydrolase target Lipase inhibitor OPIDN-OP
Phenyl-BDPO Organophosphate NTE inhibitor Cyclic OP Not AlphaBeta Hydrolase target OPIDN-OP
OBDPO Organophosphate NTE inhibitor Cyclic OP Not AlphaBeta Hydrolase target OPIDN-OP
EOPF Organophosphate NTE inhibitor Not AlphaBeta Hydrolase target FAAH inhibitor OPIDN-OP
CBDP ACHE BCHE Carb_B_Chordata Organophosphate Cyclic OP NTE inhibitor Not AlphaBeta Hydrolase target OPIDN-OP
Chlorpyrifos ACHE Est9X Duf_3089 Carb_B_Arthropoda Trichloro Insecticide Organophosphate Sulfur Compound Organothiophosphate OPIDN-OP
DPDCVP Organophosphate NTE inhibitor Not AlphaBeta Hydrolase target OPIDN-OP
Dibutyl-dichlorovinyl-phosphate~DBVP Carb_B_Chordata Organophosphate NTE inhibitor Not AlphaBeta Hydrolase target OPIDN-OP
Leptophos ACHE Insecticide Organophosphate Sulfur Compound Organothiophosphate OPIDN-OP
Phenyl-saligenin-phosphate~PSP BCHE Organophosphate Cyclic OP NTE inhibitor Not AlphaBeta Hydrolase target OPIDN-OP
DPPF Organophosphate NTE inhibitor Not AlphaBeta Hydrolase target OPIDN-OP
OSF Monoglyceridelipase_lysophospholip Sulfur Compound NTE inhibitor Not AlphaBeta Hydrolase target Sulfonyl OPIDN-OP
Tolserine ACHE BCHE Derivative of physostigmine-eserine Carbamate Indole NTE inhibitor Not AlphaBeta Hydrolase target OPIDN-OP
Tricresyl-phosphate ACHE BCHE Organophosphate Organophosphorus flame retardant plasticizer OPIDN-OP
Tri-o-cresylphosphate BCHE Organophosphate Organophosphorus flame retardant plasticizer OPIDN-OP