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Neuromuscular Nondepolarizing Agents

General

Drugs that interrupt transmission at the skeletal neuromuscular junction without causing depolarization of the motor end plate. They prevent acetylcholine from triggering muscle contraction and are used as muscle relaxants during electroshock treatments, in convulsive states, and as anesthesia adjuvants.
Inhibitor Main targeted enzyme families Type Structure
Mylaxen BCHE Neuromuscular Nondepolarizing Agents Drug Fluoren
17-desoxypancuronium BCHE Nicotinic antagonist Neuromuscular Nondepolarizing Agents Not A\/B H target Acetate Phenanthrene
Atracurium BCHE Not A\/B H target Neuromuscular Nondepolarizing Agents Drug Isoquinoline Propionate
D-tubocurarine ACHE Natural Alkaloid Neuromuscular Nondepolarizing Agents Not A\/B H target Drug
Decamethonium BCHE Bisquaternary Trimethylammonium Neuromuscular Nondepolarizing Agents Nicotinic antagonist Drug Not A\/B H target
Dibutyrate-pancuronium BCHE Butyrate Nicotinic antagonist Not A\/B H target Phenanthrene Neuromuscular Nondepolarizing Agents
Duador BCHE Pyrrolidine Neuromuscular Nondepolarizing Agents Quinoline Not A\/B H target
Gallamine~Flaxedil ACHE BCHE Neuromuscular Nondepolarizing Agents Nicotinic antagonist Not A\/B H target
Mivacurium BCHE Neuromuscular Nondepolarizing Agents Isoquinoline Bisquaternary Drug Not A\/B H target
Pancuronium BCHE Nicotinic antagonist Neuromuscular Nondepolarizing Agents Not A\/B H target Aminosteroid
Succinylcholine~Suxamethonium BCHE Neuromuscular Nondepolarizing Agents Bisquaternary Trimethylammonium Not A\/B H target
Vecuronium BCHE Neuromuscular Nondepolarizing Agents Nicotinic antagonist Aminosteroid Piperidine Drug Acetate Not A\/B H target
Pipecuronium BCHE Neuromuscular Nondepolarizing Agents Nicotinic antagonist Aminosteroid Piperazine Phenanthrene Not A\/B H target
Rocuronium Neuromuscular Nondepolarizing Agents Aminosteroid Drug Not A\/B H target Morpholine Phenanthrene
Doxacurium BCHE Neuromuscular Nondepolarizing Agents Isoquinoline Bisquaternary Not A\/B H target
Cisatracurium BCHE Propionate Isoquinoline Neuromuscular Nondepolarizing Agents Nicotinic antagonist Bisquaternary Not A\/B H target