mouse-Q8BLF1

Mus musculus (Mouse) KIAA1363 NCEH1 neutral cholesterol ester hydrolase 1 B230106I24RIK

Comment

Trembl Q8BYQ0 is incomplete

Relationship

Family : Arylacetamide_deacetylase

Block : H

Position in NCBI Life Tree : Mus musculus

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Metazoa N E > Eumetazoa N E > Bilateria N E > Deuterostomia N E > Chordata N E > Craniata N E > Vertebrata N E > Gnathostomata N E > Teleostomi N E > Euteleostomi N E > Sarcopterygii N E > Dipnotetrapodomorpha N E > Tetrapoda N E > Amniota N E > Mammalia N E > Theria N E > Eutheria N E > Boreoeutheria N E > Euarchontoglires N E > Glires N E > Rodentia N E > Myomorpha N E > Muroidea N E > Muridae N E > Murinae N E > Mus [genus] N E > Mus [subgenus] N E > Mus musculus N E

Molecular evidence

No mutation

No structure

No kinetic

No disease

No substrate

No inhibitor

Sequence

Peptide

MRSSCVLLAA LLALAAYYVY IPLPSAVSDP WKLMLLDATF RGAQQVSNLI HSLGLNHHLI ALNFIITSFG KQSARSSPKV KVTDTDFDGV EVRVFEGSPK PEEPLRRSVI YIHGGGWALA SAKISYYDQL CTTMAEELNA VIVSIEYRLV PQVYFPEQIH DVIRATKYFL QPEVLDKYKV DPGRVGISGD SAGGNLAAAL GQQFTYVASL KNKLKLQALV YPVLQALDFN TPSYQQSMNT PILPRHVMVR YWLDYFKGNY DFVEAMIVNN HTSLDVERAA ALRARLDWTS LLPSSIKKNY KPIMQTTGNA RIVQEIPQLL DAAASPLIAE QEVLEALPKT YILTCEHDVL RDDGIMYAKR LESAGVNVTL DHFEDGFHGC MIFTSWPTNF SVGIRTRNSY IKWLDQNL

References (9)

Title : Cholesteryl ester hydrolase activity is abolished in HSL-\/- macrophages but unchanged in macrophages lacking KIAA1363 - Buchebner_2010_J.Lipid.Res_51_2896
Author(s) : Buchebner M , Pfeifer T , Rathke N , Chandak PG , Lass A , Schreiber R , Kratzer A , Zimmermann R , Sattler W , Koefeler H , Frohlich E , Kostner GM , Birner-Gruenberger R , Chiang KP , Haemmerle G , Zechner R , Levak-Frank S , Cravatt B , Kratky D
Ref : J Lipid Res , 51 :2896 , 2010
PubMedID: 20625037
Gene_locus related to this paper: human-NCEH1 , mouse-Q8BLF1

Title : Ablation of neutral cholesterol ester hydrolase 1 accelerates atherosclerosis - Sekiya_2009_Cell.Metab_10_219
Author(s) : Sekiya M , Osuga J , Nagashima S , Ohshiro T , Igarashi M , Okazaki H , Takahashi M , Tazoe F , Wada T , Ohta K , Takanashi M , Kumagai M , Nishi M , Takase S , Yahagi N , Yagyu H , Ohashi K , Nagai R , Kadowaki T , Furukawa Y , Ishibashi S
Ref : Cell Metab , 10 :219 , 2009
PubMedID: 19723498
Gene_locus related to this paper: human-NCEH1 , mouse-Q8BLF1

Title : Organophosphate-sensitive lipases modulate brain lysophospholipids, ether lipids and endocannabinoids - Casida_2008_Chem.Biol.Interact_175_355
Author(s) : Casida JE , Nomura DK , Vose SC , Fujioka K
Ref : Chemico-Biological Interactions , 175 :355 , 2008
PubMedID: 18495101
Gene_locus related to this paper: human-NCEH1 , mouse-Q8BLF1

Title : Serine hydrolase KIAA1363: toxicological and structural features with emphasis on organophosphate interactions - Nomura_2006_Chem.Res.Toxicol_19_1142
Author(s) : Nomura DK , Durkin KA , Chiang KP , Quistad GB , Cravatt BF , Casida JE
Ref : Chemical Research in Toxicology , 19 :1142 , 2006
PubMedID: 16978018
Gene_locus related to this paper: human-NCEH1 , mouse-Q8BLF1

Title : An enzyme that regulates ether lipid signaling pathways in cancer annotated by multidimensional profiling - Chiang_2006_Chem.Biol_13_1041
Author(s) : Chiang KP , Niessen S , Saghatelian A , Cravatt BF
Ref : Chemical Biology , 13 :1041 , 2006
PubMedID: 17052608
Gene_locus related to this paper: human-NCEH1 , mouse-Q8BLF1

Title : A brain detoxifying enzyme for organophosphorus nerve poisons - Nomura_2005_Proc.Natl.Acad.Sci.U.S.A_102_6195
Author(s) : Nomura DK , Leung D , Chiang KP , Quistad GB , Cravatt BF , Casida JE
Ref : Proc Natl Acad Sci U S A , 102 :6195 , 2005
PubMedID: 15840715
Gene_locus related to this paper: human-NCEH1 , mouse-Q8BLF1

Title : Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries - Okazaki_2004_DNA.Res_11_205
Author(s) : Okazaki N , R FK , Ohara R , Inamoto S , Koseki H , Hiraoka S , Saga Y , Seino S , Nishimura M , Kaisho T , Hoshino K , Kitamura H , Nagase T , Ohara O , Koga H
Ref : DNA Research , 11 :205 , 2004
PubMedID: 15368895
Gene_locus related to this paper: mouse-2neur , mouse-F135A , mouse-ndr2 , mouse-Q8BLF1

Title : Enzyme activity profiles of the secreted and membrane proteome that depict cancer cell invasiveness - Jessani_2002_Proc.Natl.Acad.Sci.U.S.A_99_10335
Author(s) : Jessani N , Liu Y , Humphrey M , Cravatt BF
Ref : Proc Natl Acad Sci U S A , 99 :10335 , 2002
PubMedID: 12149457
Gene_locus related to this paper: human-NCEH1 , mouse-Q8BLF1

Title : Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs - Okazaki_2002_Nature_420_563
Author(s) : Okazaki Y , Furuno M , Kasukawa T , Adachi J , Bono H , Kondo S , Nikaido I , Osato N , Saito R , Suzuki H , Yamanaka I , Kiyosawa H , Yagi K , Tomaru Y , Hasegawa Y , Nogami A , Schonbach C , Gojobori T , Baldarelli R , Hill DP , Bult C , Hume DA , Quackenbush J , Schriml LM , Kanapin A , Matsuda H , Batalov S , Beisel KW , Blake JA , Bradt D , Brusic V , Chothia C , Corbani LE , Cousins S , Dalla E , Dragani TA , Fletcher CF , Forrest A , Frazer KS , Gaasterland T , Gariboldi M , Gissi C , Godzik A , Gough J , Grimmond S , Gustincich S , Hirokawa N , Jackson IJ , Jarvis ED , Kanai A , Kawaji H , Kawasawa Y , Kedzierski RM , King BL , Konagaya A , Kurochkin IV , Lee Y , Lenhard B , Lyons PA , Maglott DR , Maltais L , Marchionni L , McKenzie L , Miki H , Nagashima T , Numata K , Okido T , Pavan WJ , Pertea G , Pesole G , Petrovsky N , Pillai R , Pontius JU , Qi D , Ramachandran S , Ravasi T , Reed JC , Reed DJ , Reid J , Ring BZ , Ringwald M , Sandelin A , Schneider C , Semple CA , Setou M , Shimada K , Sultana R , Takenaka Y , Taylor MS , Teasdale RD , Tomita M , Verardo R , Wagner L , Wahlestedt C , Wang Y , Watanabe Y , Wells C , Wilming LG , Wynshaw-Boris A , Yanagisawa M , Yang I , Yang L , Yuan Z , Zavolan M , Zhu Y , Zimmer A , Carninci P , Hayatsu N , Hirozane-Kishikawa T , Konno H , Nakamura M , Sakazume N , Sato K , Shiraki T , Waki K , Kawai J , Aizawa K , Arakawa T , Fukuda S , Hara A , Hashizume W , Imotani K , Ishii Y , Itoh M , Kagawa I , Miyazaki A , Sakai K , Sasaki D , Shibata K , Shinagawa A , Yasunishi A , Yoshino M , Waterston R , Lander ES , Rogers J , Birney E , Hayashizaki Y
Ref : Nature , 420 :563 , 2002
PubMedID: 12466851
Gene_locus related to this paper: mouse-1lipg , mouse-1llip , mouse-1plrp , mouse-3neur , mouse-ABH15 , mouse-abhd4 , mouse-abhd5 , mouse-Abhd8 , mouse-Abhd11 , mouse-abhda , mouse-acot4 , mouse-adcl4 , mouse-AI607300 , mouse-BAAT , mouse-bphl , mouse-C87498 , mouse-Ldah , mouse-Ces1d , mouse-Ces2e , mouse-CMBL , mouse-DGLB , mouse-dpp9 , mouse-ES10 , mouse-F135A , mouse-FASN , mouse-hslip , mouse-hyes , mouse-Kansl3 , mouse-LIPH , mouse-LIPK , mouse-lipli , mouse-LIPM , mouse-lypla1 , mouse-lypla2 , mouse-MEST , mouse-MGLL , mouse-ndr4 , mouse-OVCA2 , mouse-pafa , mouse-pcp , mouse-ppce , mouse-Ppgb , mouse-PPME1 , mouse-q3uuq7 , mouse-Q8BLF1 , mouse-ACOT6 , mouse-Q8C1A9 , mouse-Q9DAI6 , mouse-Q80UX8 , mouse-Q8BGG9 , mouse-Q8C167 , mouse-rbbp9 , mouse-SERHL , mouse-tssp