Fritz C

References (5)

Title : The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI - Bussey_1997_Nature_387_103
Author(s) : Bussey H , Storms RK , Ahmed A , Albermann K , Allen E , Ansorge W , Araujo R , Aparicio A , Barrell B , Badcock K , Benes V , Botstein D , Bowman S , Bruckner M , Carpenter J , Cherry JM , Chung E , Churcher C , Coster F , Davis K , Davis RW , Dietrich FS , Delius H , DiPaolo T , Dubois E , Dusterhoft A , Duncan M , Floeth M , Fortin N , Friesen JD , Fritz C , Goffeau A , Hall J , Hebling U , Heumann K , Hilbert H , Hillier L , Hunicke-Smith S , Hyman R , Johnston M , Kalman S , Kleine K , Komp C , Kurdi O , Lashkari D , Lew H , Lin A , Lin D , Louis EJ , Marathe R , Messenguy F , Mewes HW , Mirtipati S , Moestl D , Muller-Auer S , Namath A , Nentwich U , Oefner P , Pearson D , Petel FX , Pohl TM , Purnelle B , Rajandream MA , Rechmann S , Rieger M , Riles L , Roberts D , Schafer M , Scharfe M , Scherens B , Schramm S , Schroder M , Sdicu AM , Tettelin H , Urrestarazu LA , Ushinsky S , Vierendeels F , Vissers S , Voss H , Walsh SV , Wambutt R , Wang Y , Wedler E , Wedler H , Winnett E , Zhong WW , Zollner A , Vo DH , Hani J
Ref : Nature , 387 :103 , 1997
Abstract : The nucleotide sequence of the 948,061 base pairs of chromosome XVI has been determined, completing the sequence of the yeast genome. Chromosome XVI was the last yeast chromosome identified, and some of the genes mapped early to it, such as GAL4, PEP4 and RAD1 (ref. 2) have played important roles in the development of yeast biology. The architecture of this final chromosome seems to be typical of the large yeast chromosomes, and shows large duplications with other yeast chromosomes. Chromosome XVI contains 487 potential protein-encoding genes, 17 tRNA genes and two small nuclear RNA genes; 27% of the genes have significant similarities to human gene products, and 48% are new and of unknown biological function. Systematic efforts to explore gene function have begun.
ESTHER : Bussey_1997_Nature_387_103
PubMedSearch : Bussey_1997_Nature_387_103
PubMedID: 9169875
Gene_locus related to this paper: yeast-MCFS1 , yeast-YPR147C

Title : The complete genome sequence of the gram-positive bacterium Bacillus subtilis - Kunst_1997_Nature_390_249
Author(s) : Kunst F , Ogasawara N , Moszer I , Albertini AM , Alloni G , Azevedo V , Bertero MG , Bessieres P , Bolotin A , Borchert S , Borriss R , Boursier L , Brans A , Braun M , Brignell SC , Bron S , Brouillet S , Bruschi CV , Caldwell B , Capuano V , Carter NM , Choi SK , Cordani JJ , Connerton IF , Cummings NJ , Daniel RA , Denziot F , Devine KM , Dusterhoft A , Ehrlich SD , Emmerson PT , Entian KD , Errington J , Fabret C , Ferrari E , Foulger D , Fritz C , Fujita M , Fujita Y , Fuma S , Galizzi A , Galleron N , Ghim SY , Glaser P , Goffeau A , Golightly EJ , Grandi G , Guiseppi G , Guy BJ , Haga K , Haiech J , Harwood CR , Henaut A , Hilbert H , Holsappel S , Hosono S , Hullo MF , Itaya M , Jones L , Joris B , Karamata D , Kasahara Y , Klaerr-Blanchard M , Klein C , Kobayashi Y , Koetter P , Koningstein G , Krogh S , Kumano M , Kurita K , Lapidus A , Lardinois S , Lauber J , Lazarevic V , Lee SM , Levine A , Liu H , Masuda S , Mauel C , Medigue C , Medina N , Mellado RP , Mizuno M , Moestl D , Nakai S , Noback M , Noone D , O'Reilly M , Ogawa K , Ogiwara A , Oudega B , Park SH , Parro V , Pohl TM , Portelle D , Porwollik S , Prescott AM , Presecan E , Pujic P , Purnelle B , Rapoport G , Rey M , Reynolds S , Rieger M , Rivolta C , Rocha E , Roche B , Rose M , Sadaie Y , Sato T , Scanlan E , Schleich S , Schroeter R , Scoffone F , Sekiguchi J , Sekowska A , Seror SJ , Serror P , Shin BS , Soldo B , Sorokin A , Tacconi E , Takagi T , Takahashi H , Takemaru K , Takeuchi M , Tamakoshi A , Tanaka T , Terpstra P , Togoni A , Tosato V , Uchiyama S , Vandebol M , Vannier F , Vassarotti A , Viari A , Wambutt R , Wedler H , Weitzenegger T , Winters P , Wipat A , Yamamoto H , Yamane K , Yasumoto K , Yata K , Yoshida K , Yoshikawa HF , Zumstein E , Yoshikawa H , Danchin A
Ref : Nature , 390 :249 , 1997
Abstract : Bacillus subtilis is the best-characterized member of the Gram-positive bacteria. Its genome of 4,214,810 base pairs comprises 4,100 protein-coding genes. Of these protein-coding genes, 53% are represented once, while a quarter of the genome corresponds to several gene families that have been greatly expanded by gene duplication, the largest family containing 77 putative ATP-binding transport proteins. In addition, a large proportion of the genetic capacity is devoted to the utilization of a variety of carbon sources, including many plant-derived molecules. The identification of five signal peptidase genes, as well as several genes for components of the secretion apparatus, is important given the capacity of Bacillus strains to secrete large amounts of industrially important enzymes. Many of the genes are involved in the synthesis of secondary metabolites, including antibiotics, that are more typically associated with Streptomyces species. The genome contains at least ten prophages or remnants of prophages, indicating that bacteriophage infection has played an important evolutionary role in horizontal gene transfer, in particular in the propagation of bacterial pathogenesis.
ESTHER : Kunst_1997_Nature_390_249
PubMedSearch : Kunst_1997_Nature_390_249
PubMedID: 9384377
Gene_locus related to this paper: bacsu-CAH , bacsu-cbxnp , bacsu-lip , bacsu-LIPB , bacsu-PKSR , bacsu-pnbae , bacsu-PPSE , bacsu-srf4 , bacsu-srfac , bacsu-YBAC , bacsu-YBDG , bacsu-ybfk , bacsu-ycgS , bacsu-yczh , bacsu-YDEN , bacsu-ydjp , bacsu-yfhM , bacsu-yisY , bacsu-YITV , bacsu-yjau , bacsu-YJCH , bacsu-MHQD , bacsu-yqjl , bacsu-yqkd , bacsu-YRAK , bacsu-YTAP , bacsu-YTMA , bacsu-YTPA , bacsu-ytxm , bacsu-yugF , bacsu-YUII , bacsu-YUKL , bacsu-YVAK , bacsu-YvaM , bacsu-RsbQ

Title : The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications - Philippsen_1997_Nature_387_93
Author(s) : Philippsen P , Kleine K , Pohlmann R , Dusterhoft A , Hamberg K , Hegemann JH , Obermaier B , Urrestarazu LA , Aert R , Albermann K , Altmann R , Andre B , Baladron V , Ballesta JP , Becam AM , Beinhauer J , Boskovic J , Buitrago MJ , Bussereau F , Coster F , Crouzet M , D'Angelo M , Dal Pero F , De Antoni A , del Rey F , Doignon F , Domdey H , Dubois E , Fiedler T , Fleig U , Floeth M , Fritz C , Gaillardin C , Garcia-Cantalejo JM , Glansdorff NN , Goffeau A , Gueldener U , Herbert C , Heumann K , Heuss-Neitzel D , Hilbert H , Hinni K , Iraqui Houssaini I , Jacquet M , Jimenez A , Jonniaux JL , Karpfinger L , Lanfranchi G , Lepingle A , Levesque H , Lyck R , Maftahi M , Mallet L , Maurer KC , Messenguy F , Mewes HW , Mosti D , Nasr F , Nicaud JM , Niedenthal RK , Pandolfo D , Pierard A , Piravandi E , Planta RJ , Pohl TM , Purnelle B , Rebischung C , Remacha M , Revuelta JL , Rinke M , Saiz JE , Sartorello F , Scherens B , Sen-Gupta M , Soler-Mira A , Urbanus JH , Valle G , van Dyck L , Verhasselt P , Vierendeels F , Vissers S , Voet M , Volckaert G , Wach A , Wambutt R , Wedler H , Zollner A , Hani J
Ref : Nature , 387 :93 , 1997
Abstract : In 1992 we started assembling an ordered library of cosmid clones from chromosome XIV of the yeast Saccharomyces cerevisiae. At that time, only 49 genes were known to be located on this chromosome and we estimated that 80% to 90% of its genes were yet to be discovered. In 1993, a team of 20 European laboratories began the systematic sequence analysis of chromosome XIV. The completed and intensively checked final sequence of 784,328 base pairs was released in April, 1996. Substantial parts had been published before or had previously been made available on request. The sequence contained 419 known or presumptive protein-coding genes, including two pseudogenes and three retrotransposons, 14 tRNA genes, and three small nuclear RNA genes. For 116 (30%) protein-coding sequences, one or more structural homologues were identified elsewhere in the yeast genome. Half of them belong to duplicated groups of 6-14 loosely linked genes, in most cases with conserved gene order and orientation (relaxed interchromosomal synteny). We have considered the possible evolutionary origins of this unexpected feature of yeast genome organization.
ESTHER : Philippsen_1997_Nature_387_93
PubMedSearch : Philippsen_1997_Nature_387_93
PubMedID: 9169873
Gene_locus related to this paper: yeast-SCYNR064C , yeast-hda1

Title : Complete DNA sequence of yeast chromosome II - Feldmann_1994_EMBO.J_13_5795
Author(s) : Feldmann H , Aigle M , Aljinovic G , Andre B , Baclet MC , Barthe C , Baur A , Becam AM , Biteau N , Boles E , Brandt T , Brendel M , Bruckner M , Bussereau F , Christiansen C , Contreras R , Crouzet M , Cziepluch C , Demolis N , Delaveau T , Doignon F , Domdey H , Dusterhus S , Dubois E , Dujon B , El Bakkoury M , Entian KD , Feurmann M , Fiers W , Fobo GM , Fritz C , Gassenhuber H , Glandsdorff N , Goffeau A , Grivell LA , de Haan M , Hein C , Herbert CJ , Hollenberg CP , Holmstrom K , Jacq C , Jacquet M , Jauniaux JC , Jonniaux JL , Kallesoe T , Kiesau P , Kirchrath L , Kotter P , Korol S , Liebl S , Logghe M , Lohan AJ , Louis EJ , Li ZY , Maat MJ , Mallet L , Mannhaupt G , Messenguy F , Miosga T , Molemans F , Muller S , Nasr F , Obermaier B , Perea J , Pierard A , Piravandi E , Pohl FM , Pohl TM , Potier S , Proft M , Purnelle B , Ramezani Rad M , Rieger M , Rose M , Schaaff-Gerstenschlager I , Scherens B , Schwarzlose C , Skala J , Slonimski PP , Smits PH , Souciet JL , Steensma HY , Stucka R , Urrestarazu A , van der Aart QJ , van Dyck L , Vassarotti A , Vetter I , Vierendeels F , Vissers S , Wagner G , de Wergifosse P , Wolfe KH , Zagulski M , Zimmermann FK , Mewes HW , Kleine K , Dsterhus S , Mller S , Pirard A , Schaaff-Gerstenschlger I
Ref : EMBO Journal , 13 :5795 , 1994
Abstract : In the framework of the EU genome-sequencing programmes, the complete DNA sequence of the yeast Saccharomyces cerevisiae chromosome II (807 188 bp) has been determined. At present, this is the largest eukaryotic chromosome entirely sequenced. A total of 410 open reading frames (ORFs) were identified, covering 72% of the sequence. Similarity searches revealed that 124 ORFs (30%) correspond to genes of known function, 51 ORFs (12.5%) appear to be homologues of genes whose functions are known, 52 others (12.5%) have homologues the functions of which are not well defined and another 33 of the novel putative genes (8%) exhibit a degree of similarity which is insufficient to confidently assign function. Of the genes on chromosome II, 37-45% are thus of unpredicted function. Among the novel putative genes, we found several that are related to genes that perform differentiated functions in multicellular organisms of are involved in malignancy. In addition to a compact arrangement of potential protein coding sequences, the analysis of this chromosome confirmed general chromosome patterns but also revealed particular novel features of chromosomal organization. Alternating regional variations in average base composition correlate with variations in local gene density along chromosome II, as observed in chromosomes XI and III. We propose that functional ARS elements are preferably located in the AT-rich regions that have a spacing of approximately 110 kb. Similarly, the 13 tRNA genes and the three Ty elements of chromosome II are found in AT-rich regions. In chromosome II, the distribution of coding sequences between the two strands is biased, with a ratio of 1.3:1. An interesting aspect regarding the evolution of the eukaryotic genome is the finding that chromosome II has a high degree of internal genetic redundancy, amounting to 16% of the coding capacity.
ESTHER : Feldmann_1994_EMBO.J_13_5795
PubMedSearch : Feldmann_1994_EMBO.J_13_5795
PubMedID: 7813418
Gene_locus related to this paper: yeast-LDH1 , yeast-MCFS2 , yeast-yby9

Title : Complete DNA sequence of yeast chromosome XI - Dujon_1994_Nature_369_371
Author(s) : Dujon B , Alexandraki D , Andre B , Ansorge W , Baladron V , Ballesta JP , Banrevi A , Bolle PA , Bolotin-Fukuhara M , Bossier P , Bou G , Boyer J , Bultrago MJ , Cheret G , Colleaux L , Dalgnan-Fornler B , del Rey F , Dlon C , Domdey H , Dsterhoft A , Dsterhus S , Entlan KD , Erfle H , Esteban PF , Feldmann H , Fernandes L , Robo GM , Fritz C , Fukuhara H , Gabel C , Gaillon L , Carcia-Cantalejo JM , Garcia-Ramirez JJ , Gent NE , Ghazvini M , Goffeau A , Gonzalez A , Grothues D , Guerreiro P , Hegemann J , Hewitt N , Hilger F , Hollenberg CP , Horaitis O , Indge KJ , Jacquier A , James CM , Jauniaux C , Jimenez A , Keuchel H , Kirchrath L , Kleine K , Ktter P , Legrain P , Liebl S , Louis EJ , Maia e Silva A , Marck C , Monnier AL , Mostl D , Mller S , Obermaier B , Oliver SG , Pallier C , Pascolo S , Pfeiffer F , Philippsen P , Planta RJ , Pohl FM , Pohl TM , Pohlmann R , Portetelle D , Purnelle B , Puzos V , Ramezani Rad M , Rasmussen SW , Remacha M , Revuelta JL , Richard GF , Rieger M , Rodrigues-Pousada C , Rose M , Rupp T , Santos MA , Schwager C , Sensen C , Skala J , Soares H , Sor F , Stegemann J , Tettelin H , Thierry A , Tzermia M , Urrestarazu LA , van Dyck L , Van Vliet-Reedijk JC , Valens M , Vandenbo M , Vilela C , Vissers S , von Wettstein D , Voss H , Wiemann S , Xu G , Zimmermann J , Haasemann M , Becker I , Mewes HW
Ref : Nature , 369 :371 , 1994
Abstract : The complete DNA sequence of the yeast Saccharomyces cerevisiae chromosome XI has been determined. In addition to a compact arrangement of potential protein coding sequences, the 666,448-base-pair sequence has revealed general chromosome patterns; in particular, alternating regional variations in average base composition correlate with variations in local gene density along the chromosome. Significant discrepancies with the previously published genetic map demonstrate the need for using independent physical mapping criteria.
ESTHER : Dujon_1994_Nature_369_371
PubMedSearch : Dujon_1994_Nature_369_371
PubMedID: 8196765
Gene_locus related to this paper: yeast-mgll