Gene_Locus Report

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Gene_locus Report for: rat-d3zhq1

Rattus norvegicus (Rat) DPP8

Relationship
Family|DPP4N_Peptidase_S9
Block| X
Position in NCBI Life Tree|Rattus norvegicus
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Metazoa: N E > Eumetazoa: N E > Bilateria: N E > Deuterostomia: N E > Chordata: N E > Craniata: N E > Vertebrata: N E > Gnathostomata: N E > Teleostomi: N E > Euteleostomi: N E > Sarcopterygii: N E > Dipnotetrapodomorpha: N E > Tetrapoda: N E > Amniota: N E > Mammalia: N E > Theria: N E > Eutheria: N E > Boreoeutheria: N E > Euarchontoglires: N E > Glires: N E > Rodentia: N E > Myomorpha: N E > Muroidea: N E > Muridae: N E > Murinae: N E > Rattus: N E > Rattus norvegicus: N E


Molecular evidence
Database
No mutation
No structure
No kinetic





No Substrate
No inhibitor
1 Genbank : CH473975
1 UniProt : D3ZHQ1
1 UniProt : D3ZHQ1
1 Interpro : D3ZHQ1
1 Prodom : D3ZHQ1
1 Pfam : D3ZHQ1
1 PIRSF : D3ZHQ1
1 SUPERFAM : D3ZHQ1
Sequence
Graphical view for this peptide sequence: rat-d3zhq1
Colored MSA for DPP4N_Peptidase_S9 (raw)
MKIPSGRCNMAAAMETEQLGVEIFETAECEEGNGESQDRPKLEPFYVERY
SWSQLKKLLTDTRKYHGYMMAKAPHDFMFVKRADPDGPHSDRVYYLAMSG
ENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLR
ERKRIGTVGIAAYDYHPGSGTFLFQAGSGIYHIKDGGPHGFTQQPLRPNL
VETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNLVTREERRLTYVHNEL
ASMEEDPRSAGVATFVLQEEFDRYSGYWWCPQAERTPSGGKILRILYEEN
DESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIVVDAEGGI
IDVIDKELVQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTHLQIVL
ISPELFIPVEDDAMDRQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVF
PQTHEDEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKC
PIKEEIAITSGEWEVLGRHGSNIWVDEARKLVYFEGTKDSPLEHHLYVTS
YANPGDVVRLTDRGYSHSCCLSRHCDFFISKYSNQKSPHCVSLYKLSSPD
DDPVHKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDL
QPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRG
SCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASQYDFIDLDRVGIHGWSY
GGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGY
YLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYD
LQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVM
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

MKIPSGRCNMAAAMETEQLGVEIFETAECEEGNGESQDRPKLEPFYVERY
SWSQLKKLLTDTRKYHGYMMAKAPHDFMFVKRADPDGPHSDRVYYLAMSG
ENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLR
ERKRIGTVGIAAYDYHPGSGTFLFQAGSGIYHIKDGGPHGFTQQPLRPNL
VETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNLVTREERRLTYVHNEL
ASMEEDPRSAGVATFVLQEEFDRYSGYWWCPQAERTPSGGKILRILYEEN
DESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIVVDAEGGI
IDVIDKELVQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTHLQIVL
ISPELFIPVEDDAMDRQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVF
PQTHEDEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKC
PIKEEIAITSGEWEVLGRHGSNIWVDEARKLVYFEGTKDSPLEHHLYVTS
YANPGDVVRLTDRGYSHSCCLSRHCDFFISKYSNQKSPHCVSLYKLSSPD
DDPVHKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDL
QPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRG
SCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASQYDFIDLDRVGIHGWSY
GGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGY
YLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYD
LQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVM


References
    Title: Gene and alternative splicing annotation with AIR
    Florea L, Di Francesco V, Miller J, Turner R, Yao A, Harris M, Walenz B, Mobarry C, Merkulov GV and Sutton G <5 more author(s)>
    Ref: Genome Res, 15:54, 2005 : PubMed

            

    Title: Genome sequence of the Brown Norway rat yields insights into mammalian evolution
    Gibbs RA, Weinstock GM, Metzker ML, Muzny DM, Sodergren EJ, Scherer S, Scott G, Steffen D, Worley KC and Collins F <218 more author(s)>
    Ref: Nature, 428:493, 2004 : PubMed

            


Other Papers


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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