Purine

General

Purine is a heterocyclic aromatic organic compound that consists of two rings (pyrimidine and imidazole) fused together. It is water-soluble. In nucleic acids, two types of nucleobases are purine derivatives: guanine (G) and adenine (A). Building block for many inhibitors of enzymes

Inhibitor	Main targeted enzyme families	Type
SCHEMBL22345207		Pyrrolidine Purine
1-(((piperidin)ethyl)amino)pentyl)-Caffeine-Cpd28	ACHE	Purine Alkaloid
Theobromine		Purine Alkaloid Natural Not AlphaBeta Hydrolase target
ADPr-ATP	Plant_lipase_EDS1-like	Aminopurin Purine Ribose
iso-ADP-ribose	Plant_lipase_EDS1-like	Aminopurin Purine Ribose
75J-34n	DPP4N_Peptidase_S9	Piperidine Imidazole Purine Cyanide Alkyne
Benzodioxo-purin-amine-cpd1	DPP4N_Peptidase_S9	Benzodioxo Purine Aminopurin
Valproyl-CoA	Carb_B_Chordata	CoA Sulfur Compound Purine Aminopurin
thio-NAD	PlaB	Sulfur Compound Nicotinamide Organophosphate Pyridine Purine Aminopurin
Caffeine	Pectinacetylesterase-Notum Lipase_3	Purine Alkaloid Natural Drug Not AlphaBeta Hydrolase target
Theophylline	Pectinacetylesterase-Notum	Alkaloid Natural Purine Not AlphaBeta Hydrolase target
75M-5T4F	DPP4N_Peptidase_S9	Piperidine Quinazoline Cyanide Purine Alkyne
75L-5T4E	DPP4N_Peptidase_S9	Piperidine Pyrimidine Quinazoline Purine Alkyne
75N-5T4B	DPP4N_Peptidase_S9	Piperidine Quinazoline Purine Alkyne
CHEMBL3687984	DPP4N_Peptidase_S9	Cyanide Piperidine Purine
Pyrimidinone-inhibitor1	DPP4N_Peptidase_S9	Purine Piperazine Organochlorine
Xanthine-inhibitor-4	DPP4N_Peptidase_S9	Pyrimidine Piperidine Cyanide Purine
6Z8	DPP4N_Peptidase_S9	Purine Piperidine Gliptin Peptide
BDPX	DPP4N_Peptidase_S9	Piperazine Purine
Linagliptin	DPP4N_Peptidase_S9	Drug Purine Gliptin Quinazoline Alkyne
Zeatin	ACHE	Not AlphaBeta Hydrolase target Natural Purine Aminopurin
SCHEMBL22345207		Pyrrolidine Purine
1-(((piperidin)ethyl)amino)pentyl)-Caffeine-Cpd28	ACHE	Purine Alkaloid
Theobromine		Purine Alkaloid Natural Not AlphaBeta Hydrolase target
ADPr-ATP	Plant_lipase_EDS1-like	Aminopurin Purine Ribose
iso-ADP-ribose	Plant_lipase_EDS1-like	Aminopurin Purine Ribose
75J-34n	DPP4N_Peptidase_S9	Piperidine Imidazole Purine Cyanide Alkyne
Benzodioxo-purin-amine-cpd1	DPP4N_Peptidase_S9	Benzodioxo Purine Aminopurin
Valproyl-CoA	Carb_B_Chordata	CoA Sulfur compound Purine Aminopurin
thio-NAD	PlaB	Sulfur compound Nicotinamide Organophosphate Pyridine Purine Aminopurin
Caffeine	Pectinacetylesterase-Notum Lipase_3	Purine Alkaloid Natural Drug Not AlphaBeta Hydrolase target
Theophylline	Pectinacetylesterase-Notum	Alkaloid Natural Purine Not AlphaBeta Hydrolase target
75M-5T4F	DPP4N_Peptidase_S9	Piperidine Quinazoline Cyanide Purine Alkyne
75L-5T4E	DPP4N_Peptidase_S9	Piperidine Pyrimidine Quinazoline Purine Alkyne
75N-5T4B	DPP4N_Peptidase_S9	Piperidine Quinazoline Purine Alkyne
CHEMBL3687984	DPP4N_Peptidase_S9	Cyanide Piperidine Purine
Pyrimidinone-inhibitor1	DPP4N_Peptidase_S9	Purine Piperazine Organochlorine
Xanthine-inhibitor-4	DPP4N_Peptidase_S9	Pyrimidine Piperidine Cyanide Purine
6Z8	DPP4N_Peptidase_S9	Purine Piperidine Gliptin Peptide
BDPX	DPP4N_Peptidase_S9	Piperazine Purine
Linagliptin	DPP4N_Peptidase_S9	Drug Purine Gliptin Quinazoline Alkyne
Zeatin	ACHE	Not AlphaBeta Hydrolase target Natural Purine Aminopurin
SCHEMBL22345207		Pyrrolidine Purine
1-(((piperidin)ethyl)amino)pentyl)-Caffeine-Cpd28	ACHE	Purine Alkaloid
Theobromine		Purine Alkaloid Natural Not AlphaBeta Hydrolase target
ADPr-ATP	Plant_lipase_EDS1-like	Aminopurin Purine Ribose
iso-ADP-ribose	Plant_lipase_EDS1-like	Aminopurin Purine Ribose
75J-34n	DPP4N_Peptidase_S9	Piperidine Imidazole Purine Cyanide Alkyne
Benzodioxo-purin-amine-cpd1	DPP4N_Peptidase_S9	Benzodioxo Purine Aminopurin
Valproyl-CoA	Carb_B_Chordata	CoA Sulfur compound Purine Aminopurin
thio-NAD	PlaB	Sulfur compound Nicotinamide Organophosphate Pyridine Purine Aminopurin
Caffeine	Pectinacetylesterase-Notum Lipase_3	Purine Alkaloid Natural Drug Not AlphaBeta Hydrolase target
Theophylline	Pectinacetylesterase-Notum	Alkaloid Natural Purine Not AlphaBeta Hydrolase target
75M-5T4F	DPP4N_Peptidase_S9	Piperidine Quinazoline Cyanide Purine Alkyne
75L-5T4E	DPP4N_Peptidase_S9	Piperidine Pyrimidine Quinazoline Purine Alkyne
75N-5T4B	DPP4N_Peptidase_S9	Piperidine Quinazoline Purine Alkyne
CHEMBL3687984	DPP4N_Peptidase_S9	Cyanide Piperidine Purine
Pyrimidinone-inhibitor1	DPP4N_Peptidase_S9	Purine Piperazine Organochlorine
Xanthine-inhibitor-4	DPP4N_Peptidase_S9	Pyrimidine Piperidine Cyanide Purine
6Z8	DPP4N_Peptidase_S9	Purine Piperidine Gliptin Peptide
BDPX	DPP4N_Peptidase_S9	Piperazine Purine
Linagliptin	DPP4N_Peptidase_S9	Drug Purine Gliptin Quinazoline Alkyne
Zeatin	ACHE	Not AlphaBeta Hydrolase target Natural Purine Aminopurin