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Gliptin

General

Inhibitors of dipeptidyl peptidase 4 (DPP-4 inhibitors or gliptins) are a class of oral hypoglycemics that block the enzyme dipeptidyl peptidase-4 (DPP-4). They can be used to treat diabetes mellitus type 2
Inhibitor Main targeted enzyme families Type Structure
Retagliptin DPP4N_Peptidase_S9 Drug Gliptin Triazol Trifluoro Pro-Drug Imidazole
Cofrogliptin DPP4N_Peptidase_S9 Gliptin Trifluoro Pyrazole Sulfonamide Sulfur Compound
Fotagliptin DPP4N_Peptidase_S9 Gliptin Cyanide Piperidine Triazine
Prusogliptin DPP4N_Peptidase_S9 Gliptin Trifluoro Cyanide Pyrrolidine
SCHEMBL21862936 DPP4N_Peptidase_S9 Gliptin Trifluoro Azabicyclo Oxadiazol
Neogliptin DPP4N_Peptidase_S9 Gliptin Trifluoro Cyanide Azabicyclo
DA-12166 DPP4N_Peptidase_S9 Gliptin Trifluoro
DA-12228 DPP4N_Peptidase_S9 Gliptin Trifluoro Piperazine
Anagliptin DPP4N_Peptidase_S9 Drug Cyanide Pyrrolidine Gliptin Pyrimidine Carboxamide Pyrazole
Carmegliptin DPP4N_Peptidase_S9 Drug Pyrrolidine Gliptin Quinolizine
Dutogliptin DPP4N_Peptidase_S9 Drug Pyrrolidine Gliptin Boron compound
Gemigliptin DPP4N_Peptidase_S9 Drug Piperidine Pyrimidine Gliptin Trifluoro Delta-lactam
Gosogliptin DPP4N_Peptidase_S9 Drug Piperidine Pyrimidine Gliptin
Trelagliptin DPP4N_Peptidase_S9 Drug Piperidine Pyrimidine Cyanide Gliptin
Teneligliptin DPP4N_Peptidase_S9 Drug Piperazine Pyrrolidine Gliptin Thiazolidine Sulfur Compound Pyrazole
6Z8 DPP4N_Peptidase_S9 Purine Piperidine Gliptin Peptide
Evogliptin DPP4N_Peptidase_S9 Drug Gliptin Trifluoro
Saxagliptin DPP4N_Peptidase_S9 Adamantyl Drug Cyanide Pyrrolidine Gliptin Azabicyclo
Omarigliptin DPP4N_Peptidase_S9 Sulfur Compound Gliptin Pyrazole
Linagliptin DPP4N_Peptidase_S9 Drug Purine Gliptin Quinazoline Alkyne
VildaSaxagliptin-analogue DPP4N_Peptidase_S9 Pyrrolidine Gliptin Adamantyl Azabicyclo
Indol-adamantyl-carbamate-Cpd42 DPP4N_Peptidase_S9 Gliptin Adamantyl Carbamate Indole Isoindole
Indol-adamantyl-carbamate-Nitrobenzooxadiazol-Cpd20 DPP4N_Peptidase_S9 Gliptin Adamantyl Carbamate Indole Oxadiazol NBD-nitro-benzoxadiazol-fluorescent Benzoxadiazole
Vildagliptin DPP4N_Peptidase_S9 Drug Pyrrolidine Gliptin Adamantyl Cyanide
Alogliptin DPP4N_Peptidase_S9 Drug Piperidine Pyrimidine Cyanide Gliptin
Sitagliptin DPP4N_Peptidase_S9 Drug Piperidine Gliptin Triazol Trifluoro
Retagliptin DPP4N_Peptidase_S9 Drug Gliptin Triazol Trifluoro Pro-Drug Imidazole
Cofrogliptin DPP4N_Peptidase_S9 Gliptin Trifluoro Pyrazole Sulfonamide Sulfur compound
Fotagliptin DPP4N_Peptidase_S9 Gliptin Cyanide Piperidine Triazine
Prusogliptin DPP4N_Peptidase_S9 Gliptin Trifluoro Cyanide Pyrrolidine
SCHEMBL21862936 DPP4N_Peptidase_S9 Gliptin Trifluoro Azabicyclo Oxadiazol
Neogliptin DPP4N_Peptidase_S9 Gliptin Trifluoro Cyanide Azabicyclo
DA-12166 DPP4N_Peptidase_S9 Gliptin Trifluoro
DA-12228 DPP4N_Peptidase_S9 Gliptin Trifluoro Piperazine
Anagliptin DPP4N_Peptidase_S9 Drug Cyanide Pyrrolidine Gliptin Pyrimidine Carboxamide Pyrazole
Carmegliptin DPP4N_Peptidase_S9 Drug Pyrrolidine Gliptin Quinolizine
Dutogliptin DPP4N_Peptidase_S9 Drug Pyrrolidine Gliptin Boron compound
Gemigliptin DPP4N_Peptidase_S9 Drug Piperidine Pyrimidine Gliptin Trifluoro Delta-lactam
Gosogliptin DPP4N_Peptidase_S9 Drug Piperidine Pyrimidine Gliptin
Trelagliptin DPP4N_Peptidase_S9 Drug Piperidine Pyrimidine Cyanide Gliptin
Teneligliptin DPP4N_Peptidase_S9 Drug Piperazine Pyrrolidine Gliptin Thiazolidine Sulfur compound Pyrazole
6Z8 DPP4N_Peptidase_S9 Purine Piperidine Gliptin Peptide
Evogliptin DPP4N_Peptidase_S9 Drug Gliptin Trifluoro
Saxagliptin DPP4N_Peptidase_S9 Adamantyl Drug Cyanide Pyrrolidine Gliptin Azabicyclo
Omarigliptin DPP4N_Peptidase_S9 Sulfur compound Gliptin Pyrazole
Linagliptin DPP4N_Peptidase_S9 Drug Purine Gliptin Quinazoline Alkyne
VildaSaxagliptin-analogue DPP4N_Peptidase_S9 Pyrrolidine Gliptin Adamantyl Azabicyclo
Indol-adamantyl-carbamate-Cpd42 DPP4N_Peptidase_S9 Gliptin Adamantyl Carbamate Indole Isoindole
Indol-adamantyl-carbamate-Nitrobenzooxadiazol-Cpd20 DPP4N_Peptidase_S9 Gliptin Adamantyl Carbamate Indole Oxadiazol NBD-nitro-benzoxadiazol-fluorescent Benzoxadiazole
Vildagliptin DPP4N_Peptidase_S9 Drug Pyrrolidine Gliptin Adamantyl Cyanide
Alogliptin DPP4N_Peptidase_S9 Drug Piperidine Pyrimidine Cyanide Gliptin
Sitagliptin DPP4N_Peptidase_S9 Drug Piperidine Gliptin Triazol Trifluoro
Retagliptin DPP4N_Peptidase_S9 Drug Gliptin Triazol Trifluoro Pro-Drug Imidazole
Cofrogliptin DPP4N_Peptidase_S9 Gliptin Trifluoro Pyrazole Sulfonamide Sulfur compound
Fotagliptin DPP4N_Peptidase_S9 Gliptin Cyanide Piperidine Triazine
Prusogliptin DPP4N_Peptidase_S9 Gliptin Trifluoro Cyanide Pyrrolidine
SCHEMBL21862936 DPP4N_Peptidase_S9 Gliptin Trifluoro Azabicyclo Oxadiazol
Neogliptin DPP4N_Peptidase_S9 Gliptin Trifluoro Cyanide Azabicyclo
DA-12166 DPP4N_Peptidase_S9 Gliptin Trifluoro
DA-12228 DPP4N_Peptidase_S9 Gliptin Trifluoro Piperazine
Anagliptin DPP4N_Peptidase_S9 Drug Cyanide Pyrrolidine Gliptin Pyrimidine Carboxamide Pyrazole
Carmegliptin DPP4N_Peptidase_S9 Drug Pyrrolidine Gliptin Quinolizine
Dutogliptin DPP4N_Peptidase_S9 Drug Pyrrolidine Gliptin Boron compound
Gemigliptin DPP4N_Peptidase_S9 Drug Piperidine Pyrimidine Gliptin Trifluoro Delta-lactam
Gosogliptin DPP4N_Peptidase_S9 Drug Piperidine Pyrimidine Gliptin
Trelagliptin DPP4N_Peptidase_S9 Drug Piperidine Pyrimidine Cyanide Gliptin
Teneligliptin DPP4N_Peptidase_S9 Drug Piperazine Pyrrolidine Gliptin Thiazolidine Sulfur compound Pyrazole
6Z8 DPP4N_Peptidase_S9 Purine Piperidine Gliptin Peptide
Evogliptin DPP4N_Peptidase_S9 Drug Gliptin Trifluoro
Saxagliptin DPP4N_Peptidase_S9 Adamantyl Drug Cyanide Pyrrolidine Gliptin Azabicyclo
Omarigliptin DPP4N_Peptidase_S9 Sulfur compound Gliptin Pyrazole
Linagliptin DPP4N_Peptidase_S9 Drug Purine Gliptin Quinazoline Alkyne
VildaSaxagliptin-analogue DPP4N_Peptidase_S9 Pyrrolidine Gliptin Adamantyl Azabicyclo
Indol-adamantyl-carbamate-Cpd42 DPP4N_Peptidase_S9 Gliptin Adamantyl Carbamate Indole Isoindole
Indol-adamantyl-carbamate-Nitrobenzooxadiazol-Cpd20 DPP4N_Peptidase_S9 Gliptin Adamantyl Carbamate Indole Oxadiazol NBD-nitro-benzoxadiazol-fluorescent Benzoxadiazole
Vildagliptin DPP4N_Peptidase_S9 Drug Pyrrolidine Gliptin Adamantyl Cyanide
Alogliptin DPP4N_Peptidase_S9 Drug Piperidine Pyrimidine Cyanide Gliptin
Sitagliptin DPP4N_Peptidase_S9 Drug Piperidine Gliptin Triazol Trifluoro