Pyridazine

General

Pyridazine is a heterocyclic organic compound with the molecular formula (CH)4N2. It contains a six-membered ring with two adjacent nitrogen atoms, and is aromatic. The pyridazine structure is a popular pharmacophore. It is isomeric with two other (CH)4N2 rings, pyrimidine and pyrazine.

Inhibitor	Main targeted enzyme families	Type
Benzylpiperidin-dimethylamino-hydroxyphenyl-pyridazin-one-Cpd7a	ACHE	Pyridazine Piperidine anti-Abeta-aggregation Multitarget Benzylpiperidine Derivative of Donepezil
CHEMBL5176418	BCHE ACHE	Pyridazine anti-Abeta-aggregation Multitarget Alkyl linked bis-ligand
A1IKD	BCHE	Naphthalen Pyridine Pyridazine
A1IKC	BCHE	Naphthalen Pyridine Pyridazine
FP9	Epoxide_hydrolase	Pyridazine Urea derivative Trifluoro
Pyridyl-Pyridazine-Glycoside-cpd5	BCHE ACHE	Pyridazine Triazol Sulfur Compound Glycoside
Carboxylesterase-IN-2	Pectinacetylesterase-Notum	Pyridazine Triazol Sulfur Compound
ARUK3003778	Pectinacetylesterase-Notum	Fragment inhibitor of Notum Sulfur Compound Triazol Pyridazine Organochlorine
ARUK3002697	Pectinacetylesterase-Notum	Fragment inhibitor of Notum Triazol Pyridazine Sulfur Compound
ARUK3003934	Pectinacetylesterase-Notum	Fragment inhibitor of Notum Triazol Pyridazine Sulfur Compound
Maybridge_56	Pectinacetylesterase-Notum	Fragment inhibitor of Notum Pyridazine Organochlorine
ARUK3003902	Pectinacetylesterase-Notum	Fragment inhibitor of Notum Triazol Pyridazine Sulfur Compound Organochlorine
ARUK3003909	Pectinacetylesterase-Notum	Fragment inhibitor of Notum Triazol Trifluoro Pyridazine Sulfur Compound
ARUK3003776	Pectinacetylesterase-Notum	Fragment inhibitor of Notum Pyridazine Triazol Azabicyclo Sulfur Compound Organochlorine
ARUK3003775	Pectinacetylesterase-Notum	Fragment inhibitor of Notum Pyridazine Triazol Sulfur Compound Organochlorine
ARUK3003748	Pectinacetylesterase-Notum	Fragment inhibitor of Notum Pyridazine Triazol Sulfur Compound
Pyridaphenthion	ACHE	Organophosphate Insecticide Sulfur Compound Pyridazine Pyrazole
Benzylpiperidin-dimethylamino-hydroxyphenyl-pyridazin-one-Cpd7a	ACHE	Pyridazine Piperidine anti-Abeta-aggregation Multitarget Benzylpiperidine Derivative of Donepezil
CHEMBL5176418	BCHE ACHE	Pyridazine anti-Abeta-aggregation Multitarget Alkyl linked bis-ligand
A1IKD	BCHE	Naphthalen Pyridine Pyridazine
A1IKC	BCHE	Naphthalen Pyridine Pyridazine
FP9	Epoxide_hydrolase	Pyridazine Urea derivative Trifluoro
Pyridyl-Pyridazine-Glycoside-cpd5	BCHE ACHE	Pyridazine Triazol Sulfur compound Glycoside
Carboxylesterase-IN-2	Pectinacetylesterase-Notum	Pyridazine Triazol Sulfur compound
ARUK3003778	Pectinacetylesterase-Notum	Fragment inhibitor of Notum Sulfur compound Triazol Pyridazine Organochlorine
ARUK3002697	Pectinacetylesterase-Notum	Fragment inhibitor of Notum Triazol Pyridazine Sulfur compound
ARUK3003934	Pectinacetylesterase-Notum	Fragment inhibitor of Notum Triazol Pyridazine Sulfur compound
Maybridge_56	Pectinacetylesterase-Notum	Fragment inhibitor of Notum Pyridazine Organochlorine
ARUK3003902	Pectinacetylesterase-Notum	Fragment inhibitor of Notum Triazol Pyridazine Sulfur compound Organochlorine
ARUK3003909	Pectinacetylesterase-Notum	Fragment inhibitor of Notum Triazol Trifluoro Pyridazine Sulfur compound
ARUK3003776	Pectinacetylesterase-Notum	Fragment inhibitor of Notum Pyridazine Triazol Azabicyclo Sulfur compound Organochlorine
ARUK3003775	Pectinacetylesterase-Notum	Fragment inhibitor of Notum Pyridazine Triazol Sulfur compound Organochlorine
ARUK3003748	Pectinacetylesterase-Notum	Fragment inhibitor of Notum Pyridazine Triazol Sulfur compound
Pyridaphenthion	ACHE	Organophosphate Insecticide Sulfur compound Pyridazine Pyrazole
Benzylpiperidin-dimethylamino-hydroxyphenyl-pyridazin-one-Cpd7a	ACHE	Pyridazine Piperidine anti-Abeta-aggregation Multitarget Benzylpiperidine Derivative of Donepezil
CHEMBL5176418	BCHE ACHE	Pyridazine anti-Abeta-aggregation Multitarget Alkyl linked bis-ligand
A1IKD	BCHE	Naphthalen Pyridine Pyridazine
A1IKC	BCHE	Naphthalen Pyridine Pyridazine
FP9	Epoxide_hydrolase	Pyridazine Urea derivative Trifluoro
Pyridyl-Pyridazine-Glycoside-cpd5	BCHE ACHE	Pyridazine Triazol Sulfur compound Glycoside
Carboxylesterase-IN-2	Pectinacetylesterase-Notum	Pyridazine Triazol Sulfur compound
ARUK3003778	Pectinacetylesterase-Notum	Fragment inhibitor of Notum Sulfur compound Triazol Pyridazine Organochlorine
ARUK3002697	Pectinacetylesterase-Notum	Fragment inhibitor of Notum Triazol Pyridazine Sulfur compound
ARUK3003934	Pectinacetylesterase-Notum	Fragment inhibitor of Notum Triazol Pyridazine Sulfur compound
Maybridge_56	Pectinacetylesterase-Notum	Fragment inhibitor of Notum Pyridazine Organochlorine
ARUK3003902	Pectinacetylesterase-Notum	Fragment inhibitor of Notum Triazol Pyridazine Sulfur compound Organochlorine
ARUK3003909	Pectinacetylesterase-Notum	Fragment inhibitor of Notum Triazol Trifluoro Pyridazine Sulfur compound
ARUK3003776	Pectinacetylesterase-Notum	Fragment inhibitor of Notum Pyridazine Triazol Azabicyclo Sulfur compound Organochlorine
ARUK3003775	Pectinacetylesterase-Notum	Fragment inhibitor of Notum Pyridazine Triazol Sulfur compound Organochlorine
ARUK3003748	Pectinacetylesterase-Notum	Fragment inhibitor of Notum Pyridazine Triazol Sulfur compound
Pyridaphenthion	ACHE	Organophosphate Insecticide Sulfur compound Pyridazine Pyrazole