CoA

Esters of coenzyme A. Coenzyme A (CoA, SHCoA, CoASH) is a coenzyme, notable for its role in the synthesis and oxidation of fatty acids, and the oxidation of pyruvate in the citric acid cycle. The thiol can react with carboxylic acids to form thioesters, thus functioning as an acyl group carrier.

Substrate	Main targeted enzyme families	Type
3-hydroxyphenyloctanoyl-CoA	PHA_depolymerase_arom	Octanoate CoA Sulfur Compound
C6-CoA	AlphaBeta_hydrolase	CoA Sulfur Compound
Mycophenolic-acid-CoA	MpaH	CoA Natural Benzofuran Aminopurin Purine
3HB-CoA	PHA_synth_I PHA_synth_III_C PHA_synth_II	CoA Aminopurin Purine
Cholyl-CoA	Acyl-CoA_Thioesterase	CoA Aminopurin Phenanthrene Purine
Coenzyme-A	6_AlphaBeta_hydrolase Carb_B_Chordata CIB-CCG1-interacting-factor-B	CoA Aminopurin Purine
Acetyl-CoA	Homoserine_transacetylase AlphaBeta_hydrolase	CoA Aminopurin Purine
Malonyl-CoA	5_AlphaBeta_hydrolase 6_AlphaBeta_hydrolase ABHD11-Acetyl_transferase	CoA Aminopurin Purine
Palmitoyl-CoA	Acyl-CoA_Thioesterase abh_upf00227 6_AlphaBeta_hydrolase LYsophospholipase_carboxylesterase A85-EsteraseD-FGH MenH_SHCHC Palmitoyl-protein_thioesterase Carb_B_Chordata ABHD11-Acetyl_transferase	CoA Aminopurin Hexadecanoate Palmitate Purine
Oleoyl-CoA	Carboxylesterase Carb_B_Chordata	Natural CoA Aminopurin Purine
3-hydroxyphenyloctanoyl-CoA	PHA_depolymerase_arom	Octanoate CoA Sulfur Compound
C6-CoA	AlphaBeta_hydrolase	CoA Sulfur Compound
Mycophenolic-acid-CoA	MpaH	CoA Natural Benzofuran Aminopurin Purine
3HB-CoA	PHA_synth_I PHA_synth_III_C PHA_synth_II	CoA Aminopurin Purine
Cholyl-CoA	Acyl-CoA_Thioesterase	CoA Aminopurin Phenanthrene Purine
Coenzyme-A	6_AlphaBeta_hydrolase Carb_B_Chordata CIB-CCG1-interacting-factor-B	CoA Aminopurin Purine
Acetyl-CoA	Homoserine_transacetylase AlphaBeta_hydrolase	CoA Aminopurin Purine
Malonyl-CoA	5_AlphaBeta_hydrolase 6_AlphaBeta_hydrolase ABHD11-Acetyl_transferase	CoA Aminopurin Purine
Palmitoyl-CoA	Acyl-CoA_Thioesterase abh_upf00227 6_AlphaBeta_hydrolase LYsophospholipase_carboxylesterase A85-EsteraseD-FGH MenH_SHCHC Palmitoyl-protein_thioesterase Carb_B_Chordata ABHD11-Acetyl_transferase	CoA Aminopurin Hexadecanoate Palmitate Purine
Oleoyl-CoA	Carboxylesterase Carb_B_Chordata	Natural CoA Aminopurin Purine
3-hydroxyphenyloctanoyl-CoA	PHA_depolymerase_arom	Octanoate CoA Sulfur Compound
C6-CoA	AlphaBeta_hydrolase	CoA Sulfur Compound
Mycophenolic-acid-CoA	MpaH	CoA Natural Benzofuran Aminopurin Purine
3HB-CoA	PHA_synth_I PHA_synth_III_C PHA_synth_II	CoA Aminopurin Purine
Cholyl-CoA	Acyl-CoA_Thioesterase	CoA Aminopurin Phenanthrene Purine
Coenzyme-A	6_AlphaBeta_hydrolase Carb_B_Chordata CIB-CCG1-interacting-factor-B	CoA Aminopurin Purine
Acetyl-CoA	Homoserine_transacetylase AlphaBeta_hydrolase	CoA Aminopurin Purine
Malonyl-CoA	5_AlphaBeta_hydrolase 6_AlphaBeta_hydrolase ABHD11-Acetyl_transferase	CoA Aminopurin Purine
Palmitoyl-CoA	Acyl-CoA_Thioesterase abh_upf00227 6_AlphaBeta_hydrolase LYsophospholipase_carboxylesterase A85-EsteraseD-FGH MenH_SHCHC Palmitoyl-protein_thioesterase Carb_B_Chordata ABHD11-Acetyl_transferase	CoA Aminopurin Hexadecanoate Palmitate Purine
Oleoyl-CoA	Carboxylesterase Carb_B_Chordata	Natural CoA Aminopurin Purine