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Author Report for: Martin BR

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    Title: Protein depalmitoylases
    Won SJ, Cheung See Kit M, Martin BR
    Ref: Crit Rev Biochem Mol Biol, 53:83, 2018 : PubMed

            

    Title: Temporal Profiling Establishes a Dynamic S-Palmitoylation Cycle
    Won SJ, Martin BR
    Ref: ACS Chemical Biology, 13:1560, 2018 : PubMed

            

    Title: APT2 Inhibition Restores Scribble Localization and S-Palmitoylation in Snail-Transformed Cells
    Hernandez JL, Davda D, Cheung See Kit M, Majmudar JD, Won SJ, Gang M, Pasupuleti SC, Choi AI, Bartkowiak CM, Martin BR
    Ref: Cell Chemical Biology, 24:87, 2017 : PubMed

            

    Title: Affinity-Based Selectivity Profiling of an In-Class Selective Competitive Inhibitor of Acyl Protein Thioesterase 2
    Won SJ, Eschweiler JD, Majmudar JD, Chong FS, Hwang SY, Ruotolo BT, Martin BR
    Ref: ACS Med Chem Lett, 8:215, 2017 : PubMed

            

    Title: Human lysosomal acid lipase inhibitor lalistat impairs Mycobacterium tuberculosis growth by targeting bacterial hydrolases
    Davda D, Martin BR
    Ref: Medchemcomm, 7:1797, 2014 : PubMed

            

    Title: Molecular Mechanism for Isoform-Selective Inhibition of Acyl Protein Thioesterases 1 and 2 (APT1 and APT2)
    Won SJ, Davda D, Labby KJ, Hwang SY, Pricer R, Majmudar JD, Armacost KA, Rodriguez LA, Rodriguez CL and Martin BR <7 more author(s)>
    Ref: ACS Chemical Biology, 11:3374, 2016 : PubMed

            

    Title: Global Analysis of Palmitoylated Proteins in Toxoplasma gondii
    Foe IT, Child MA, Majmudar JD, Krishnamurthy S, van der Linden WA, Ward GE, Martin BR, Bogyo M
    Ref: Cell Host Microbe, 18:501, 2015 : PubMed

            

    Title: Substrate-Competitive Activity-Based Profiling of Ester Prodrug Activating Enzymes
    Xu H, Majmudar JD, Davda D, Ghanakota P, Kim KH, Carlson HA, Showalter HD, Martin BR, Amidon GL
    Ref: Mol Pharm, 12:3399, 2015 : PubMed

            

    Title: Acyl protein thioesterase inhibitors as probes of dynamic S-palmitoylation
    Davda D, Martin BR
    Ref: Medchemcomm, 5:268, 2014 : PubMed

            

    Title: A mechanism regulating G protein-coupled receptor signaling that requires cycles of protein palmitoylation and depalmitoylation
    Jia L, Chisari M, Maktabi MH, Sobieski C, Zhou H, Konopko AM, Martin BR, Mennerick SJ, Blumer KJ
    Ref: Journal of Biological Chemistry, 289:6249, 2014 : PubMed

            

    Title: Characterization of a Selective, Reversible Inhibitor of Lysophospholipase 1 (LYPLA1)
    Adibekian A, Martin BR, Chang JW, Hsu KL, Tsuboi K, Bachovchin DA, Speers AE, Brown SJ, Spicer T and Rosen H <4 more author(s)>
    Ref: Probe Report, :, 2013 : PubMed

            

    Title: Characterization of a Selective, Reversible Inhibitor of Lysophospholipase 2 (LYPLA2)
    Adibekian A, Martin BR, Chang JW, Hsu KL, Tsuboi K, Bachovchin DA, Speers AE, Brown SJ, Spicer T and Rosen H <4 more author(s)>
    Ref: Probe Report, :, 2013 : PubMed

            

    Title: Confirming target engagement for reversible inhibitors in vivo by kinetically tuned activity-based probes
    Adibekian A, Martin BR, Chang JW, Hsu KL, Tsuboi K, Bachovchin DA, Speers AE, Brown SJ, Spicer T and Cravatt BF <4 more author(s)>
    Ref: J Am Chem Soc, 134:10345, 2012 : PubMed

            

    Title: Global profiling of dynamic protein palmitoylation
    Martin BR, Wang C, Adibekian A, Tully SE, Cravatt BF
    Ref: Nat Methods, 9:84, 2012 : PubMed

            

    Title: Click-generated triazole ureas as ultrapotent in vivo-active serine hydrolase inhibitors
    Adibekian A, Martin BR, Wang C, Hsu KL, Bachovchin DA, Niessen S, Hoover H, Cravatt BF
    Ref: Nat Chemical Biology, 7:469, 2011 : PubMed

            

    Title: Optimization and characterization of a triazole urea dual inhibitor for lysophospholipase 1 (LYPLA1) and lysophospholipase 2 (LYPLA2)
    Adibekian A, Martin BR, Speers AE, Brown SJ, Spicer T, Fernandez-Vega V, Ferguson J, Cravatt BF, Hodder P, Rosen H
    Ref: Probe Report, :, 2011 : PubMed

            

    Title: Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 3'-(substituted phenyl)epibatidine analogues. Nicotinic partial agonists
    Carroll FI, Ma W, Deng L, Navarro HA, Damaj MI, Martin BR
    Ref: Journal of Natural Products, 73:306, 2010 : PubMed

            

    Title: The role of various nicotinic receptor subunits and factors influencing nicotine conditioned place aversion
    Jackson KJ, Kota DH, Martin BR, Damaj MI
    Ref: Neuropharmacology, 56:970, 2009 : PubMed

            

    Title: Characterization of pharmacological and behavioral differences to nicotine in C57Bl/6 and DBA/2 mice
    Jackson KJ, Walters CL, Miles MF, Martin BR, Damaj MI
    Ref: Neuropharmacology, 57:347, 2009 : PubMed

            

    Title: Large-scale profiling of protein palmitoylation in mammalian cells
    Martin BR, Cravatt BF
    Ref: Nat Methods, 6:135, 2009 : PubMed

            

    Title: 3'-Fluoro substitution in the pyridine ring of epibatidine improves selectivity and efficacy for alpha4beta2 versus alpha3beta4 nAChRs
    Abdrakhmanova GR, Carroll FI, Damaj MI, Martin BR
    Ref: Neuropharmacology, 55:1287, 2008 : PubMed

            

    Title: Synthesis, nicotinic acetylcholine receptor binding, and pharmacological properties of 3'-(substituted phenyl)deschloroepibatidine analogs
    Ivy Carroll F, Yokota Y, Ma W, Lee JR, Brieaddy LE, Burgess JP, Navarro HA, Damaj MI, Martin BR
    Ref: Bioorganic & Medicinal Chemistry, 16:746, 2008 : PubMed

            

    Title: Differential role of nicotinic acetylcholine receptor subunits in physical and affective nicotine withdrawal signs
    Jackson KJ, Martin BR, Changeux JP, Damaj MI
    Ref: Journal of Pharmacology & Experimental Therapeutics, 325:302, 2008 : PubMed

            

    Title: Age-dependent differences in nicotine reward and withdrawal in female mice
    Kota D, Martin BR, Damaj MI
    Ref: Psychopharmacology (Berl), 198:201, 2008 : PubMed

            

    Title: The endogenous cannabinoid system modulates nicotine reward and dependence
    Merritt LL, Martin BR, Walters C, Lichtman AH, Damaj MI
    Ref: Journal of Pharmacology & Experimental Therapeutics, 326:483, 2008 : PubMed

            

    Title: Synthesis and nicotinic acetylcholine receptor binding properties of bridged and fused ring analogues of epibatidine
    Carroll FI, Robinson TP, Brieaddy LE, Atkinson RN, Mascarella SW, Damaj MI, Martin BR, Navarro HA
    Ref: Journal of Medicinal Chemistry, 50:6383, 2007 : PubMed

            

    Title: RhoA, encoding a Rho GTPase, is associated with smoking initiation
    Chen X, Che Y, Zhang L, Putman AH, Damaj MI, Martin BR, Kendler KS, Miles MF
    Ref: Genes Brain Behav, 6:689, 2007 : PubMed

            

    Title: Genetic approaches identify differential roles for alpha4beta2* nicotinic receptors in acute models of antinociception in mice
    Damaj MI, Fonck C, Marks MJ, Deshpande P, Labarca C, Lester HA, Collins AC, Martin BR
    Ref: Journal of Pharmacology & Experimental Therapeutics, 321:1161, 2007 : PubMed

            

    Title: Inhibition of nicotine metabolism by methoxysalen: Pharmacokinetic and pharmacological studies in mice
    Damaj MI, Siu EC, Sellers EM, Tyndale RF, Martin BR
    Ref: Journal of Pharmacology & Experimental Therapeutics, 320:250, 2007 : PubMed

            

    Title: Synthesis, nicotinic acetylcholine receptor binding, antinociceptive and seizure properties of methyllycaconitine analogs
    Ivy Carroll F, Ma W, Navarro HA, Abraham P, Wolckenhauer SA, Damaj MI, Martin BR
    Ref: Bioorganic & Medicinal Chemistry, 15:678, 2007 : PubMed

            

    Title: Nicotine dependence and reward differ between adolescent and adult male mice
    Kota D, Martin BR, Robinson SE, Damaj MI
    Ref: Journal of Pharmacology & Experimental Therapeutics, 322:399, 2007 : PubMed

            

    Title: Evaluation of fatty acid amide hydrolase inhibition in murine models of emotionality
    Naidu PS, Varvel SA, Ahn K, Cravatt BF, Martin BR, Lichtman AH
    Ref: Psychopharmacology (Berl), 192:61, 2007 : PubMed

            

    Title: Assessment of anandamide's pharmacological effects in mice deficient of both fatty acid amide hydrolase and cannabinoid CB1 receptors
    Wise LE, Shelton CC, Cravatt BF, Martin BR, Lichtman AH
    Ref: European Journal of Pharmacology, 557:44, 2007 : PubMed

            

    Title: 2-Fluoro-3-(4-nitro-phenyl)deschloroepibatidine is a novel potent competitive antagonist of human neuronal alpha4beta2 nAChRs
    Abdrakhmanova GR, Damaj MI, Carroll FI, Martin BR
    Ref: Molecular Pharmacology, 69:1945, 2006 : PubMed

            

    Title: Synthesis and pharmacological characterization of nicotinic acetylcholine receptor properties of (+)- and (-)-pyrido-[3,4-b]homotropanes
    Carroll FI, Hu X, Navarro HA, Deschamps J, Abdrakhmanova GR, Damaj MI, Martin BR
    Ref: Journal of Medicinal Chemistry, 49:3244, 2006 : PubMed

            

    Title: Nicotine place preference in the mouse: influences of prior handling, dose and strain and attenuation by nicotinic receptor antagonists
    Grabus SD, Martin BR, Brown SE, Damaj MI
    Ref: Psychopharmacology (Berl), 184:456, 2006 : PubMed

            

    Title: Synthesis and pharmacological characterization of exo-2-(2'-chloro-5-pyridinyl)-7-(endo and exo)-aminobicyclo[2.2.1]heptanes as novel epibatidine analogues
    Carroll FI, Brieaddy LE, Navarro HA, Damaj MI, Martin BR
    Ref: Journal of Medicinal Chemistry, 48:7491, 2005 : PubMed

            

    Title: Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 3'-substituted deschloroepibatidine analogues. Novel nicotinic antagonists
    Carroll FI, Ma W, Yokota Y, Lee JR, Brieaddy LE, Navarro HA, Damaj MI, Martin BR
    Ref: Journal of Medicinal Chemistry, 48:1221, 2005 : PubMed

            

    Title: Effect of dextrometorphan and dextrorphan on nicotine and neuronal nicotinic receptors: in vitro and in vivo selectivity
    Damaj MI, Flood P, Ho KK, May EL, Martin BR
    Ref: Journal of Pharmacology & Experimental Therapeutics, 312:780, 2005 : PubMed

            

    Title: In vivo characterization of a novel inhibitor of CNS nicotinic receptors
    Damaj MI, Wiley JL, Martin BR, Papke RL
    Ref: European Journal of Pharmacology, 521:43, 2005 : PubMed

            

    Title: Nicotine physical dependence and tolerance in the mouse following chronic oral administration
    Grabus SD, Martin BR, Batman AM, Tyndale RF, Sellers E, Damaj MI
    Ref: Psychopharmacology (Berl), 178:183, 2005 : PubMed

            

    Title: Influence of the degree of unsaturation of the acyl side chain upon the interaction of analogues of 1-arachidonoylglycerol with monoacylglycerol lipase and fatty acid amide hydrolase
    Vandevoorde S, Saha B, Mahadevan A, Razdan RK, Pertwee RG, Martin BR, Fowler CJ
    Ref: Biochemical & Biophysical Research Communications, 337:104, 2005 : PubMed

            

    Title: Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2'-fluoro-3'-(substituted phenyl)deschloroepibatidine analogues. Novel nicotinic antagonist
    Carroll FI, Ware R, Brieaddy LE, Navarro HA, Damaj MI, Martin BR
    Ref: Journal of Medicinal Chemistry, 47:4588, 2004 : PubMed

            

    Title: Enantioselective effects of hydroxy metabolites of bupropion on behavior and on function of monoamine transporters and nicotinic receptors
    Damaj MI, Carroll FI, Eaton JB, Navarro HA, Blough BE, Mirza S, Lukas RJ, Martin BR
    Ref: Molecular Pharmacology, 66:675, 2004 : PubMed

            

    Title: Intrathecal CART (55-102) enhances the spinal analgesic actions of morphine in mice
    Damaj MI, Hunter RG, Martin BR, Kuhar MJ
    Ref: Brain Research, 1024:146, 2004 : PubMed

            

    Title: 3-(4-Aminobutyn-1-yl)pyridines: binding at alpha 4 beta 2 nicotinic cholinergic receptors
    Dogruer D, Lee M, Dukat M, Damaj MI, Martin BR, Glennon RA
    Ref: Bioorganic & Medicinal Chemistry Lett, 14:523, 2004 : PubMed

            

    Title: (+/-)8-Amino-5,6,7,8-tetrahydroisoquinolines as novel antinociceptive agents
    Dukat M, Taroua M, Dahdouh A, Siripurapu U, Damaj MI, Martin BR, Glennon RA
    Ref: Bioorganic & Medicinal Chemistry Lett, 14:3651, 2004 : PubMed

            

    Title: Inhibition of monoacylglycerol lipase and fatty acid amide hydrolase by analogues of 2-arachidonoylglycerol
    Ghafouri N, Tiger G, Razdan RK, Mahadevan A, Pertwee RG, Martin BR, Fowler CJ
    Ref: British Journal of Pharmacology, 143:774, 2004 : PubMed

            

    Title: Characterization of spontaneous and precipitated nicotine withdrawal in the mouse
    Damaj MI, Kao W, Martin BR
    Ref: Journal of Pharmacology & Experimental Therapeutics, 307:526, 2003 : PubMed

            

    Title: Antinociceptive effects of supraspinal rat cart (55-102) peptide in mice
    Damaj MI, Martin BR, Kuhar MJ
    Ref: Brain Research, 983:233, 2003 : PubMed

            

    Title: Binding of nicotine and homoazanicotine analogues at neuronal nicotinic acetylcholinergic (nACh) receptors
    Ferretti G, Dukat M, Giannella M, Piergentili A, Pigini M, Quaglia W, Damaj MI, Martin BR, Glennon RA
    Ref: Bioorganic & Medicinal Chemistry Lett, 13:733, 2003 : PubMed

            

    Title: Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2-exo-2-(2',3'-disubstituted 5'-pyridinyl)-7-azabicyclo[2.2.1]heptanes: epibatidine analogues
    Carroll FI, Lee JR, Navarro HA, Ma W, Brieaddy LE, Abraham P, Damaj MI, Martin BR
    Ref: Journal of Medicinal Chemistry, 45:4755, 2002 : PubMed

            

    Title: Functional diversity among 5-substituted nicotine analogs; in vitro and in vivo investigations
    Dukat M, Damaj MI, Young R, Vann R, Collins AC, Marks MJ, Martin BR, Glennon RA
    Ref: European Journal of Pharmacology, 435:171, 2002 : PubMed

            

    Title: (-)6-n-Propylnicotine antagonizes the antinociceptive effects of (-)nicotine
    Dukat M, El-Zahabi M, Ferretti G, Damaj MI, Martin BR, Young R, Glennon RA
    Ref: Bioorganic & Medicinal Chemistry Lett, 12:3005, 2002 : PubMed

            

    Title: Homoazanicotine: a structure-affinity study for nicotinic acetylcholine (nACh) receptor binding
    Ferretti G, Dukat M, Giannella M, Piergentili A, Pigini M, Quaglia W, Damaj MI, Martin BR, Glennon RA
    Ref: Journal of Medicinal Chemistry, 45:4724, 2002 : PubMed

            

    Title: Nicotine-like discriminative stimulus effects of bupropion in rats
    Wiley JL, Lavecchia KL, Martin BR, Damaj MI
    Ref: Experimental & Clinical Psychopharmacology, 10:129, 2002 : PubMed

            

    Title: Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2-exo-2-(2'-substituted-3'-phenyl-5'-pyridinyl)-7-azabicyclo[2.2.1]heptanes. Novel nicotinic antagonist
    Carroll FI, Lee JR, Navarro HA, Brieaddy LE, Abraham P, Damaj MI, Martin BR
    Ref: Journal of Medicinal Chemistry, 44:4039, 2001 : PubMed

            

    Title: Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2-exo-2-(2'-substituted 5'-pyridinyl)-7-azabicyclo[2.2.1]heptanes. Epibatidine analogues
    Carroll FI, Liang F, Navarro HA, Brieaddy LE, Abraham P, Damaj MI, Martin BR
    Ref: Journal of Medicinal Chemistry, 44:2229, 2001 : PubMed

            

    Title: Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase
    Cravatt BF, Demarest K, Patricelli MP, Bracey MH, Giang DK, Martin BR, Lichtman AH
    Ref: Proc Natl Acad Sci U S A, 98:9371, 2001 : PubMed

            

    Title: Highly selective CB(1) cannabinoid receptor ligands and novel CB(1)/VR(1) vanilloid receptor hybrid ligands
    Di Marzo V, Bisogno T, De Petrocellis L, Brandi I, Jefferson RG, Winckler RL, Davis JB, Dasse O, Mahadevan A and Martin BR <1 more author(s)>
    Ref: Biochemical & Biophysical Research Communications, 281:444, 2001 : PubMed

            

    Title: The antinociceptive effects of alpha7 nicotinic agonists in an acute pain model
    Damaj MI, Meyer EM, Martin BR
    Ref: Neuropharmacology, 39:2785, 2000 : PubMed

            

    Title: Chain-lengthened and imidazoline analogues of nicotine
    Ferretti G, Dukat M, Giannella M, Piergentili A, Pigini M, Quaglia W, Damaj MI, Martin BR, Glennon RA
    Ref: Bioorganic & Medicinal Chemistry Lett, 10:2665, 2000 : PubMed

            

    Title: Cannabinoid properties of methylfluorophosphonate analogs
    Martin BR, Beletskaya I, Patrick G, Jefferson R, Winckler R, Deutsch DG, Di Marzo V, Dasse O, Mahadevan A, Razdan RK
    Ref: Journal of Pharmacology & Experimental Therapeutics, 294:1209, 2000 : PubMed

            

    Title: Symposium overview: mechanism of action of nicotine on neuronal acetylcholine receptors, from molecule to behavior
    Narahashi T, Fenster CP, Quick MW, Lester RA, Marszalec W, Aistrup GL, Sattelle DB, Martin BR, Levin ED
    Ref: Toxicol Sci, 57:193, 2000 : PubMed

            

    Title: Bupropion is a nicotinic antagonist
    Slemmer JE, Martin BR, Damaj MI
    Ref: Journal of Pharmacology & Experimental Therapeutics, 295:321, 2000 : PubMed

            

    Title: Antinociceptive and pharmacological effects of metanicotine, a selective nicotinic agonist
    Damaj MI, Glassco W, Aceto MD, Martin BR
    Ref: Journal of Pharmacology & Experimental Therapeutics, 291:390, 1999 : PubMed

            

    Title: Pharmacological characterization of nicotine-induced seizures in mice
    Damaj MI, Glassco W, Dukat M, Martin BR
    Ref: Journal of Pharmacology & Experimental Therapeutics, 291:1284, 1999 : PubMed

            

    Title: Pharmacological characterization of nicotine's interaction with cocaine and cocaine analogs
    Damaj MI, Slemmer JE, Carroll FI, Martin BR
    Ref: Journal of Pharmacology & Experimental Therapeutics, 289:1229, 1999 : PubMed

            

    Title: Antinociceptive responses to nicotinic acetylcholine receptor ligands after systemic and intrathecal administration in mice
    Damaj MI, Fei-Yin M, Dukat M, Glassco W, Glennon RA, Martin BR
    Ref: Journal of Pharmacology & Experimental Therapeutics, 284:1058, 1998 : PubMed

            

    Title: Pharmacological investigation of (+)- and (-)-cis-2,3,3a,4,5,9b-hexahydro-1-methyl-1H-pyrrolo-[3,2-h]isoq uinoline, a bridged-nicotine analog
    Damaj MI, Glassco W, Marks MJ, Slobe B, James JR, May EL, Rosecrans JA, Collins AC, Martin BR
    Ref: Journal of Pharmacology & Experimental Therapeutics, 282:1425, 1997 : PubMed

            

    Title: Pharmacology of lobeline, a nicotinic receptor ligand
    Damaj MI, Patrick GS, Creasy KR, Martin BR
    Ref: Journal of Pharmacology & Experimental Therapeutics, 282:410, 1997 : PubMed

            

    Title: Tolerance to the antinociceptive effect of epibatidine after acute and chronic administration in mice
    Damaj MI, Martin BR
    Ref: European Journal of Pharmacology, 300:51, 1996 : PubMed

            

    Title: Characterization and modulation of acute tolerance to nicotine in mice
    Damaj MI, Welch SP, Martin BR
    Ref: Journal of Pharmacology & Experimental Therapeutics, 277:454, 1996 : PubMed

            

    Title: Comparative pharmacology of nicotine and ABT-418, a new nicotinic agonist
    Damaj MI, Creasy KR, Welch SP, Rosecrans JA, Aceto MD, Martin BR
    Ref: Psychopharmacology (Berl), 120:483, 1995 : PubMed

            

    Title: In vivo pharmacological effects of dihydro-beta-erythroidine, a nicotinic antagonist, in mice
    Damaj MI, Welch SP, Martin BR
    Ref: Psychopharmacology (Berl), 117:67, 1995 : PubMed

            

    Title: Pharmacological effects of epibatidine optical enantiomers
    Damaj MI, Creasy KR, Grove AD, Rosecrans JA, Martin BR
    Ref: Brain Research, 664:34, 1994 : PubMed

            

    Title: Involvement of the serotonergic system in the hypoactive and antinociceptive effects of nicotine in mice
    Damaj MI, Glennon RA, Martin BR
    Ref: Brain Research Bulletin, 33:199, 1994 : PubMed

            

    Title: Nicotine-induced antinociception in mice: role of G-proteins and adenylate cyclase
    Damaj MI, Welch SP, Martin BR
    Ref: Pharmacol Biochem Behav, 48:37, 1994 : PubMed

            

    Title: Calcium agonists and antagonists of the dihydropyridine type: effect on nicotine-induced antinociception and hypomotility
    Damaj MI, Martin BR
    Ref: Drug Alcohol Depend, 32:73, 1993 : PubMed

            

    Title: Is the dopaminergic system involved in the central effects of nicotine in mice?
    Damaj MI, Martin BR
    Ref: Psychopharmacology (Berl), 111:106, 1993 : PubMed

            

    Title: Involvement of calcium and L-type channels in nicotine-induced antinociception
    Damaj MI, Welch SP, Martin BR
    Ref: Journal of Pharmacology & Experimental Therapeutics, 266:1330, 1993 : PubMed

            


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