aspfc-dpp5

 
Aspergillus fumigatus (strain CEA10/CBS 144.89/FGSC A1163) (Sartorya fumigata)(and strain Af293) Dipeptidyl-peptidase V

Relationship
Block X
Aspergillus fumigatus position in NCBI Life Tree :
N link to NCBI taxonomic web page and E link to ESTHER gene locus found in this strain.
> cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Fungi: N E > Dikarya: N E > Ascomycota: N E > saccharomyceta: N E > Pezizomycotina: N E > leotiomyceta: N E > Eurotiomycetes: N E > Eurotiomycetidae: N E > Eurotiales: N E > Aspergillaceae: N E > Aspergillus: N E > Aspergillus fumigatus: N E
Warning: This entry is a compilation of different species or line or strain with more than 90% amino acide identity. You can retrieve all strain data


Molecular evidence
Database
No mutation
No structure
No kinetic

Substrate: Lys-Ala-NA , Ser-Tyr-NA , His-Ser-MNA , Gly-Phe-pNA , APNE ,

3 Genbank : DS499595, L48074, AAHF01000001
2 UniProt : B0XRV0, P0C959
2 UniProtTrembl : B0XRV0, P0C959
2 Interpro : B0XRV0, P0C959
2 Prodom : B0XRV0, P0C959
2 Pfam : B0XRV0, P0C959
2 PIRSF : B0XRV0, P0C959
2 SUPERFAM : B0XRV0, P0C959
2 QuickSwissBlast : B0XRV0, P0C959
 
Sequence
Graphical view for this peptide sequence: aspfc-dpp5
Colored MSA for Prolyl_oligopeptidase_S9 (raw)
MGAFRWLSIAAAASTALALTPEQLITAPRRSEAIPDPSGKVAVFSTSQYS
FETHKRTSWWSLLDLKTGQTKVLTNDSSVSEIVWLSDDSILYVNSTNADI
PGGVELWVTQASSFAKGYKAASLPASFSGLKAAKTKSGDIRFVAYGQSYP
NGTAYNEELATAPLSSARIYDSIYVRHWDYWLSTTFNAVFSGTLKKGHGK
NGYSLDGELKNLVSPVKNAESPYPPFGGASDYDLSPDGKWVAFKSKAPEL
PKANFTTSYIYLVPHDASETARPINGPDSPGTPKGIKGDSSSPVFSPNGD
KLAYFQMRDETYESDRRVLYVYSLGSKKTIPSVAGDWDRSPDSVKWTPDG
KTLIVGSEDLGRTRLFSLPANAKDDYKPKNFTDGGSVSAYYFLPDSSLLV
TGSALWTNWNVYTAKPEKGVIKKIASANEIDPELKGLGPSDISEFYFQGN
FTDIHAWVIYPENFDKSKKYPLIFFIHGGPQGNWADGWSTRWNPKAWADQ
GYVVVAPNPTGSTGFGQALTDAIQNNWGGAPYDDLVKCWEYVHENLDYVD
TDHGVAAGASYGGFMINWIQGSPLGRKFKALVSHDGTFVADAKVSTEELW
FMQREFNGTFWDARDNYRRWDPSAPERILQFATPMLVIHSDKDYRLPVAE
GLSLFNVLQERGVPSRFLNFPDENHWVVNPENSLVWHQQALGWINKYSGV
EKSNPNAVSLEDTVVPVVNYN
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

MGAFRWLSIAAAASTALALTPEQLITAPRRSEAIPDPSGKVAVFSTSQYS
FETHKRTSWWSLLDLKTGQTKVLTNDSSVSEIVWLSDDSILYVNSTNADI
PGGVELWVTQASSFAKGYKAASLPASFSGLKAAKTKSGDIRFVAYGQSYP
NGTAYNEELATAPLSSARIYDSIYVRHWDYWLSTTFNAVFSGTLKKGHGK
NGYSLDGELKNLVSPVKNAESPYPPFGGASDYDLSPDGKWVAFKSKAPEL
PKANFTTSYIYLVPHDASETARPINGPDSPGTPKGIKGDSSSPVFSPNGD
KLAYFQMRDETYESDRRVLYVYSLGSKKTIPSVAGDWDRSPDSVKWTPDG
KTLIVGSEDLGRTRLFSLPANAKDDYKPKNFTDGGSVSAYYFLPDSSLLV
TGSALWTNWNVYTAKPEKGVIKKIASANEIDPELKGLGPSDISEFYFQGN
FTDIHAWVIYPENFDKSKKYPLIFFIHGGPQGNWADGWSTRWNPKAWADQ
GYVVVAPNPTGSTGFGQALTDAIQNNWGGAPYDDLVKCWEYVHENLDYVD
TDHGVAAGASYGGFMINWIQGSPLGRKFKALVSHDGTFVADAKVSTEELW
FMQREFNGTFWDARDNYRRWDPSAPERILQFATPMLVIHSDKDYRLPVAE
GLSLFNVLQERGVPSRFLNFPDENHWVVNPENSLVWHQQALGWINKYSGV
EKSNPNAVSLEDTVVPVVNYN

no DNA




References
    Title: Genomic islands in the pathogenic filamentous fungus Aspergillus fumigatus
    Fedorova ND, Khaldi N, Joardar VS, Maiti R, Amedeo P, Anderson MJ, Crabtree J, Silva JC, Badger JH and Nierman WC <29 more author(s)>
    Ref: PLoS Genet, 4:e1000046, 2008 : PubMed

            

    Title: Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus
    Nierman WC, Pain A, Anderson MJ, Wortman JR, Kim HS, Arroyo J, Berriman M, Abe K, Archer DB and Denning DW <87 more author(s)>
    Ref: Nature, 438:1151, 2005 : PubMed

            

    Title: Biochemical and antigenic characterization of a new dipeptidyl-peptidase isolated from Aspergillus fumigatus
    Beauvais A, Monod M, Debeaupuis JP, Diaquin M, Kobayashi H, Latge JP
    Ref: Journal of Biological Chemistry, 272:6238, 1997 : PubMed

            


Other Papers


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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