MHET

General

Type : Terephthalate || Phthalate || Benzoate

Chemical_Nomenclature : 4-(2-hydroxyethoxycarbonyl)benzoic acid

Canonical SMILES : C1=CC(=CC=C1C(=O)O)C(=O)OCCO

InChI : InChI=1S\/C10H10O5\/c11-5-6-15-10(14)8-3-1-7(2-4-8)9(12)13\/h1-4,11H,5-6H2,(H,12,13)

InChIKey : BCBHDSLDGBIFIX-UHFFFAOYSA-N

Other name(s) : 4-((2-Hydroxyethoxy)carbonyl)benzoic acid, Mono(ethylene terephthalate), Ethylene glycol, cyclic ester with (C7-C11)dibasic acids, AC1L5ATF, ET, C9C, 4-[(2-hydroxyethoxy)carbonyl]benzoate, 1,4-Benzenedicarboxylic acid, mono(2-hydroxyethyl) ester, CTK0G1127, CHEBI:131701, CHEBI:131704


MW : 210.18

Formula : C10H10O5

CAS_number : 1137-99-1

PubChem :

UniChem :

Iuphar :

References (16)

Title : Characterization of Thermotoga maritima Esterase Capable of Hydrolyzing Bis(2-hydroxyethyl) Terephthalate - Feng_2024_J.Agric.Food.Chem__
Author(s) : Feng S , Xue M , Xie F , Zhao H , Xue Y
Ref : Journal of Agricultural and Food Chemistry , : , 2024
PubMedID: 38753963
Gene_locus related to this paper: 9bact-a0a2h5z9r5 , thema-ESTA

Title : Complete bio-degradation of poly(butylene adipate-co-terephthalate) via engineered cutinases - Yang_2023_Nat.Commun_14_1645
Author(s) : Yang Y , Min J , Xue T , Jiang P , Liu X , Peng R , Huang JW , Qu Y , Li X , Ma N , Tsai FC , Dai L , Zhang Q , Liu Y , Chen CC , Guo RT
Ref : Nat Commun , 14 :1645 , 2023
PubMedID: 36964144
Gene_locus related to this paper: idesa-peth , thefu-q6a0i4

Title : An archaeal lid-containing feruloyl esterase degrades polyethylene terephthalate - Perez-Garcia_2023_Commun.Chem_6_193
Author(s) : Perez-Garcia P , Chow J , Costanzi E , Gurschke M , Dittrich J , Dierkes RF , Molitor R , Applegate V , Feuerriegel G , Tete P , Danso D , Thies S , Schumacher J , Pfleger C , Jaeger KE , Gohlke H , Smits SHJ , Schmitz RA , Streit WR
Ref : Commun Chem , 6 :193 , 2023
PubMedID: 37697032
Gene_locus related to this paper: 9arch-PETcan211 , 9cren-PETcan204 , 9arch-PET46

Title : Structural Insights into (Tere)phthalate-Ester Hydrolysis by a Carboxylesterase and Its Role in Promoting PET Depolymerization - von Haugwitz_2022_ACS.Catal_12_15259
Author(s) : von Haugwitz G , Han X , Pfaff L , Li Q , Wei H , Gao J , Methling K , Ao Y , Brack Y , Jan Mican J , Feiler CG , Weiss MS , Bednar D , Palm GJ , Lalk M , Lammers M , Damborsky J , Weber G , Liu W , Bornscheuer UT , Wei R
Ref : ACS Catal , 12 :15259 , 2022
PubMedID: 36570084
Gene_locus related to this paper: thefu-1831

Title : Novel efficient enzymatic synthesis of the key-reaction intermediate of PET depolymerization, mono(2-hydroxyethyl terephthalate) - MHET - de Queiros Eugenio_2022_J.Biotechnol__
Author(s) : de Queiros Eugenio E , Campisano ISP , Dias AG , de Castro AM , Coelho MAZ , Langone MAP
Ref : J Biotechnol , : , 2022
PubMedID: 36063976
Gene_locus related to this paper: humin-cut

Title : Structure-function analysis of two closely related cutinases from Thermobifida cellulosilytica - Baath_2021_Biotechnol.Bioeng__
Author(s) : Baath JA , Novy V , Carneiro LV , Guebitz GM , Olsson L , Westh P , Ribitsch D
Ref : Biotechnol Bioeng , : , 2021
PubMedID: 34755331
Gene_locus related to this paper: thefu-q6a0i4 , thefu-q6a0i3

Title : Decomposition of the PET Film by MHETase Using Exo-PETase Function - Sagong_2020_ACS.Catal_10_48050
Author(s) : Sagong HY , Seo H , Kim T , Son H , Joo S , Lee S , Kim S , Woo JS , Hwang S , Kim KJ
Ref : ACS Catal , 10 :4805 , 2020
PubMedID:
Gene_locus related to this paper: idesa-mheth

Title : Active Site Flexibility as a Hallmark for Efficient PET Degradation by I. sakaiensis PETase - Fecker_2018_Biophys.J_114_1302
Author(s) : Fecker T , Galaz-Davison P , Engelberger F , Narui Y , Sotomayor M , Parra LP , Ramirez-Sarmiento CA
Ref : Biophysical Journal , 114 :1302 , 2018
PubMedID: 29590588
Gene_locus related to this paper: idesa-peth

Title : Characterization and engineering of a plastic-degrading aromatic polyesterase - Austin_2018_Proc.Natl.Acad.Sci.U.S.A_115_E4350
Author(s) : Austin HP , Allen MD , Donohoe BS , Rorrer NA , Kearns FL , Silveira RL , Pollard BC , Dominick G , Duman R , El Omari K , Mykhaylyk V , Wagner A , Michener WE , Amore A , Skaf MS , Crowley MF , Thorne AW , Johnson CW , Woodcock HL , McGeehan JE , Beckham GT
Ref : Proc Natl Acad Sci U S A , 115 :E4350 , 2018
PubMedID: 29666242
Gene_locus related to this paper: idesa-peth

Title : Structural insight into molecular mechanism of poly(ethylene terephthalate) degradation - Joo_2018_Nat.Commun_9_382
Author(s) : Joo S , Cho IJ , Seo H , Son HF , Sagong HY , Shin TJ , Choi SY , Lee SY , Kim KJ
Ref : Nat Commun , 9 :382 , 2018
PubMedID: 29374183
Gene_locus related to this paper: idesa-peth

Title : New insights into the function and global distribution of polyethylene terephthalate (PET) degrading bacteria and enzymes in marine and terrestrial metagenomes - Danso_2018_Appl.Environ.Microbiol_84_e2773
Author(s) : Danso D , Schmeisser C , Chow J , Zimmermann W , Wei R , Leggewie C , Li X , Hazen T , Streit WR
Ref : Applied Environmental Microbiology , 84 :e2773 , 2018
PubMedID: 29427431
Gene_locus related to this paper: 9burk-PET10 , 9burk-PET11 , 9gamm-a0a0d4l7e6 , 9alte-n6vy44 , 9zzzz-a0a0f9x315 , deiml-e8u721 , olean-r4ykl9 , vibga-a0a1z2siq1 , 9burk-a0a0g3bi90 , 9bact-c3ryl0 , 9actn-h6wx58 , idesa-peth , 9bact-g9by57 , acide-PBSA , morsp-lip1

Title : Structural insight into catalytic mechanism of PET hydrolase - Han_2017_Nat.Commun_8_2106
Author(s) : Han X , Liu W , Huang JW , Ma J , Zheng Y , Ko TP , Xu L , Cheng YS , Chen CC , Guo RT
Ref : Nat Commun , 8 :2106 , 2017
PubMedID: 29235460
Gene_locus related to this paper: idesa-peth

Title : A dual enzyme system composed of a polyester hydrolase and a carboxylesterase enhances the biocatalytic degradation of polyethylene terephthalate films - Barth_2016_Biotechnol.J_11_1082
Author(s) : Barth M , Honak A , Oeser T , Wei R , Belisario-Ferrari MR , Then J , Schmidt J , Zimmermann W
Ref : Biotechnol J , 11 :1082 , 2016
PubMedID: 27214855
Gene_locus related to this paper: 9bact-g9by57 , thefu-1831

Title : A bacterium that degrades and assimilates poly(ethylene terephthalate) - Yoshida_2016_Science_351_1196
Author(s) : Yoshida S , Hiraga K , Takehana T , Taniguchi I , Yamaji H , Maeda Y , Toyohara K , Miyamoto K , Kimura Y , Oda K
Ref : Science , 351 :1196 , 2016
PubMedID: 26965627
Gene_locus related to this paper: idesa-mheth , idesa-peth

Title : Hydrolysis of polyethyleneterephthalate by p-nitrobenzylesterase from Bacillus subtilis - Ribitsch_2011_Biotechnol.Prog_27_951
Author(s) : Ribitsch D , Heumann S , Trotscha E , Herrero Acero E , Greimel K , Leber R , Birner-Gruenberger R , Deller S , Eiteljoerg I , Remler P , Weber T , Siegert P , Maurer KH , Donelli I , Freddi G , Schwab H , Guebitz GM
Ref : Biotechnol Prog , 27 :951 , 2011
PubMedID: 21574267
Gene_locus related to this paper: bacsu-pnbae

Title : Tailoring cutinase activity towards polyethylene terephthalate and polyamide 6,6 fibers - Araujo_2007_J.Biotechnol_128_849
Author(s) : Araujo R , Silva C , O'Neill A , Micaelo N , Guebitz G , Soares CMF , Casal M , Cavaco-Paulo A
Ref : J Biotechnol , 128 :849 , 2007
PubMedID: 17306400
Gene_locus related to this paper: fusso-cutas