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Haloacetate_dehalogenase

Relationship

Family: Haloacetate_dehalogenase

Block: X

Parent Family: Epoxide-hydrolase_like

Comment

As in epoxide hydrolase and haloalkane dehalogenase the catalytic triad nucleophile is an invariable aspartate. The region around the nucleophile aspartate is GHDRG. See van Loo 2006 Appl.Environ.Microbiol 72 2905

Database

Interpro : IPR000073 Alpha\/beta hydrolase fold-1

PIRSF : No PIRSF

Pdoc : No Pdoc

Pfam : PF12697 Abhydrolase_6

Prints : No Print

EC Number : No EC Number

Sequences

Peptide in Fasta
Nucleotide in Fasta
Alignment with Multalin Text only
Seed alignment with MAFFT No colour / coloured with Mview
Alignment with MAFFT No colour / coloured with Mview
Dendrogram The dnd file

Structure Name Proteins
1Y37 Structure of Fluoroacetate Dehalogenase FA1 bursp-deha
3B12 Crystal Structure of the Fluoroacetate Dehalogenase D104 mutant from Burkholderia sp. FA1 in complex with fluoroacetate bursp-deha
3QYJ Crystal structure of ALR0039, a putative alpha\/beta hydrolase from Nostoc sp PCC 7120. anasp-ALR0039
3R3U Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - WT\/apo rhopa-q6nam1
3R3V Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - Asp110Asn\/Fluoroacetate rhopa-q6nam1
3R3W Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - Asp110Asn\/Chloroacetate rhopa-q6nam1
3R3X Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - Asp110Asn\/Bromoacetate rhopa-q6nam1
3R3Y Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - His280Asn\/Fluoroacetate rhopa-q6nam1
3R3Z Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - WT\/Glycolate rhopa-q6nam1
3R40 Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - Asp110Asn\/apo rhopa-q6nam1
3R41 Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - His280Asn\/apo rhopa-q6nam1
4B9A Structure of a putative epoxide hydrolase from Pseudomonas aeruginosa. pseae-PA2086
4B9E Structure of a putative epoxide hydrolase from Pseudomonas aeruginosa, with bound MFA. pseae-PA2086
4BAT Structure of a putative epoxide hydrolase T131D mutant from Pseudomonas aeruginosa. pseae-PA2086
4BAU Structure of a putative epoxide hydrolase T131D mutant from Pseudomonas aeruginosa, with bound MFA. pseae-PA2086
4BAZ Structure of a putative epoxide hydrolase Q244E mutant from Pseudomonas aeruginosa. pseae-PA2086
4BB0 Structure of a putative epoxide hydrolase Q244E mutant from Pseudomonas aeruginosa, with bound MFA. pseae-PA2086
4NVR 2.22 Angstrom Resolution Crystal Structure of a Putative Acyltransferase from Salmonella enterica salty-STM0332
5K3A Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - His280Asn\/Fluoroacetate - Cocrystallized - Both Protomers Reacted with Ligand rhopa-q6nam1
5K3B Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - Asp110Asn\/Chloroacetate - Cocrystallized rhopa-q6nam1
5K3C Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - WT\/5-Fluorotryptophan rhopa-q6nam1
5K3D Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - WT\/Apo - No Halide rhopa-q6nam1
5K3E Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - Asp110Asn\/Glycolate - Cocrystallized rhopa-q6nam1
5K3F Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - His280Asn\/Fluoroacetate - Cocrystallized - Single Protomer Reacted with Ligand rhopa-q6nam1
5NYV Crystal structure determination from picosecond infrared laser ablated protein crystals by serial synchrotron crystallography rhopa-q6nam1
5O2G Crystal structure of the Fluoroacetate Dehalogenase RPA1163: determination from picosecond infrared laser ablated protein crystals by serial synchrotron crystallography rhopa-q6nam1
5O2I Crystal structure of the Fluoroacetate Dehalogenase RPA1163: An efficient setup for fixed-target, time-resolved serial crystallography with optical excitation rhopa-q6nam1
5SWN Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - Asp110Asn\/Glycolate - Cocrystallized rhopa-q6nam1
5T4T Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - Asp110Asn - Apo No Halide rhopa-q6nam1
6FSX Rhodopseudomonas palustris (strain ATCC BAA-98 \/ CGA009) Fluoroacetate dehalogenase rhopa-q6nam1
6GXD Rhodopseudomonas palustris Fluoroacetate dehalogenase : FAcD752MS after reaction initiation rhopa-q6nam1
6GXF Rhodopseudomonas palustris Fluoroacetate dehalogenase : RADDAM1 rhopa-q6nam1
6GXH Rhodopseudomonas palustris Fluoroacetate dehalogenase.: FAcD 0MS after reaction initiation rhopa-q6nam1
6GXL Rhodopseudomonas palustris Fluoroacetate dehalogenase : RADDAM2 rhopa-q6nam1
6GXT Rhodopseudomonas palustris Fluoroacetate dehalogenase : FAcD2052MS after reaction initiation rhopa-q6nam1
6MUH Fluoroacetate dehalogenase, room temperature structure solved by serial 1 degree oscillation crystallography rhopa-q6nam1
6MUY Fluoroacetate dehalogenase, room temperature structure solved by serial 3 degree oscillation crystallography rhopa-q6nam1
6MZZ Fluoroacetate dehalogenase, room temperature structure, using first 1 degree of total 3 degree oscillation rhopa-q6nam1
6N00 Fluoroacetate dehalogenase, room temperature structure, using last 1 degree of total 3 degree oscillation and 144 kGy dose rhopa-q6nam1
6QHP Time resolved structural analysis of the full turnover of an enzyme - 2256 ms covalent intermediate 1 rhopa-q6nam1
6QHQ Time resolved structural analysis of the full turnover of an enzyme - 1128 ms rhopa-q6nam1
6QHS Time resolved structural analysis of the full turnover of an enzyme - 13536 ms rhopa-q6nam1
6QHT Time resolved structural analysis of the full turnover of an enzyme - 376 ms rhopa-q6nam1
6QHU Time resolved structural analysis of the full turnover of an enzyme - 100 ms rhopa-q6nam1
6QHV Time resolved structural analysis of the full turnover of an enzyme - 100 ms rhopa-q6nam1
6QHW Time resolved structural analysis of the full turnover of an enzyme - 4512 ms rhopa-q6nam1
6QHX Time resolved structural analysis of the full turnover of an enzyme - 6156 ms rhopa-q6nam1
6QHY Time resolved structural analysis of the full turnover of an enzyme - 100 ms rhopa-q6nam1
6QHZ Time resolved structural analysis of the full turnover of an enzyme - 6788 ms rhopa-q6nam1
6QI0 Time resolved structural analysis of the full turnover of an enzyme - 9024 ms rhopa-q6nam1
6QI1 Time resolved structural analysis of the full turnover of an enzyme - 12312 ms rhopa-q6nam1
6QI2 Time resolved structural analysis of the full turnover of an enzyme - 13536 ms rhopa-q6nam1
6QI3 Time resolved structural analysis of the full turnover of an enzyme - 27072 ms rhopa-q6nam1
6QKS Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - Tyr219Phe - Apo rhopa-q6nam1
6QKT Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - Tyr219Phe - Fluoroacetate soaked 24hr - Glycolate bound rhopa-q6nam1
6QKU Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - Tyr219Phe - Chloroacetate soaked 2hr rhopa-q6nam1
6QKW Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - Tyr219Phe - Fluoroacetate soaked 2hr rhopa-q6nam1
7A42 Fluoroacetate Dehalogenase of Rhodopseudomonas palustris measured by serial synchrotron crystallography rhopa-q6nam1
7A43 Fluoroacetate Dehalogenase of Rhodopseudomonas palustris measured by serial femtosecond crystallography rhopa-q6nam1
8SDC Crystal structure of fluoroacetate dehalogenase Daro3835 apoenzyme decar-q479b8
8SDD Crystal structure of fluoroacetate dehalogenase Daro3835 H274N mutant with D107-glycolyl intermediate decar-q479b8

Gene_locus Name Species
9acto-b5i1i1 Streptomyces sviceus ATCC 29083 Hydrolase Streptomyces sviceus ATCC 29083
9acto-c4ri15 Micromonospora sp. ATCC 39149 Hydrolase Micromonospora sp. ATCC 39149
9acto-d1xj46 Streptomyces sp. ACTE Alpha\/beta hydrolase fold protein Streptomyces sp. ACTE
9acto-d1xn59 Streptomyces sp. ACTE Alpha\/beta hydrolase fold protein Streptomyces sp. ACTE
9acto-d3cwx4 Frankia sp. EUN1f Alpha\/beta hydrolase fold protein Frankia sp. EUN1f
9alte-a3j9g2 Marinobacter sp. ELB17 Putative uncharacterized protein Marinobacter sp. ELB17
9bact-c0aed1 Geminisphaera colitermitum TAV2 Putative hydrolase Geminisphaera colitermitum TAV2
9burk-a2w6y6 Burkholderia dolosa AUO158 Putative uncharacterized protein Burkholderia dolosa AUO158
9burk-a2wg62 Burkholderia dolosa AUO158 Putative uncharacterized protein Burkholderia dolosa AUO158
9burk-a2wja0 Burkholderia dolosa AUO158 Putative uncharacterized protein Burkholderia dolosa AUO158
9burk-b1fma7 Burkholderia ambifaria (strains IOP40-10\; ATCC BAA-244 \/ AMMD\; MEX-5\; MC40-6) (Burkholderia cepacia (strain AMMD)) Alpha\/beta hydrolase fold Burkholderia ambifaria IOP40-10
9burk-b1fvy3 Burkholderia graminis C4D1M Alpha\/beta hydrolase fold Burkholderia graminis C4D1M
9burk-b1fw54 Burkholderia graminis C4D1M Alpha\/beta hydrolase fold Burkholderia graminis C4D1M
9burk-b5wju3 Burkholderia sp. H160 Alpha\/beta hydrolase fold Burkholderia sp. H160
9burk-b5wka2 Burkholderia sp. H160 Alpha\/beta hydrolase fold Burkholderia sp. H160
9burk-c9yew1 Curvibacter putative symbiont of Hydra magnipapillata Haloacetate dehalogenase H-1 Curvibacter putative symbiont of Hydra magnipapillata
9cyan-b4vwm4 Microcoleus chthonoplastes PCC 7420 Hydrolase, alpha\/beta fold family, putative Microcoleus chthonoplastes PCC 7420
9entr-d4bjk3 Citrobacter youngae ATCC 29220 Haloacetate dehalogenase H-1 Citrobacter youngae ATCC 29220
9prot-a8tkx7 alpha proteobacterium BAL199 Putative uncharacterized protein alpha proteobacterium BAL199
9prot-a8tsz7 alpha proteobacterium BAL199 Possible epoxide hydrolase alpha proteobacterium BAL199
9psed-a0a9x2xhg3 Pseudomonas koreensis trans-epoxysuccinate hydrolase Pseudomonas koreensis
9rhiz-c8srf5 Mesorhizobium opportunistum WSM2075 Alpha\/beta hydrolase fold protein Mesorhizobium opportunistum WSM2075
9rhiz-q0g5e5 Fulvimarina pelagi HTCC2506 Alpha\/beta hydrolase Fulvimarina pelagi HTCC2506
9rhob-a0nv58 Labrenzia aggregata IAM 12614 Alpha\/beta hydrolase Labrenzia aggregata IAM 12614
9rhob-a3jvq1 Rhodobacteraceae bacterium HTCC2150 Putative uncharacterized protein Rhodobacteraceae bacterium HTCC2150
9rhob-a3jxp1 Sagittula stellata E-37 Putative uncharacterized protein Sagittula stellata E-37
9rhob-a3u2p4 Oceanicola batsensis HTCC2597 Putative uncharacterized protein Oceanicola batsensis HTCC2597
9rhob-a3v2t9 Loktanella vestfoldensis SKA53 Possible epoxide hydrolase Loktanella vestfoldensis SKA53
9rhob-a3vdy3 Maritimibacter alkaliphilus HTCC2654 Putative uncharacterized protein Maritimibacter alkaliphilus HTCC2654
9rhob-a4eft8 Roseobacter sp. CCS2 Putative uncharacterized protein Roseobacter sp. CCS2
9rhob-a4ej77 Roseobacter sp. CCS2 Putative uncharacterized protein Roseobacter sp. CCS2
9rhob-a6fnn3 Roseobacter sp. AzwK-3b Haloacetate dehalogenase H-1, putative Roseobacter sp. AzwK-3b
9rhob-a9gw39 Roseobacter litoralis Och 149 Haloacetate dehalogenase H-1, putative Roseobacter litoralis Och 149
9rhob-b5iy25 Octadecabacter antarcticus 307 Hydrolase, alpha\/beta fold family, putative Octadecabacter antarcticus 307
9rhob-b6av93 Rhodobacteraceae bacterium HTCC2083 Alpha\/beta hydrolase Rhodobacteraceae bacterium HTCC2083
9rhob-b6b2p5 Rhodobacteraceae bacterium HTCC2083 Thalassiobium sp. R2A62 Hypothetical haloacetate dehalogenase h-1 protein Rhodobacteraceae bacterium HTCC2083
9rhob-b6bc75 Rhodobacterales bacterium Y4I Haloacetate dehalogenase H-1 Rhodobacterales bacterium Y4I
9rhob-b9nwp7 Rhodobacteraceae bacterium KLH11 Haloacetate dehalogenase H-1 Rhodobacteraceae bacterium KLH11
9rhob-b9r347 Labrenzia alexandrii DFL-11 Hydrolase, alpha\/beta fold family, putative Labrenzia alexandrii DFL-11
9rhob-c7dbj7 Thalassiobium sp. R2A62 Haloacetate dehalogenase H-1 Thalassiobium sp. R2A62
9rhob-q0fad5 Rhodobacterales bacterium HTCC2255 Putative hydrolase Rhodobacterales bacterium HTCC2255
9rick-d0rqq9 alpha proteobacterium HIMB114 Haloacetate dehalogenase H-1 alpha proteobacterium HIMB114
acicj-a5fvx7 Acidiphilium cryptum (strain JF-5) Alpha\/beta hydrolase fold protein Acidiphilium cryptum
actmd-c6whm5 Actinosynnema mirum (strain ATCC 29888 \/ DSM 43827 \/ NBRC 14064 \/ IMR 3971) Alpha\/beta hydrolase fold protein Actinosynnema mirum
agrme-a0a918fe42 Agromyces mediolanus (Corynebacterium mediolanum) Fluoroacetate dehalogenase Agromyces mediolanus
agrt5-a9cle4 Agrobacterium tumefaciens (strain C58 \/ ATCC 33970) Hydrolase Agrobacterium tumefaciens
agrtu-ATU5495 Agrobacterium tumefaciens (strain C58 \/ ATCC 33970) hydrolase agr_pat_728 Agrobacterium tumefaciens
anadf-a7h7k0 Anaeromyxobacter sp. (strain Fw109-5) Alpha\/beta hydrolase fold Anaeromyxobacter sp. Fw109-5
anasp-ALR0039 Nostoc sp.\; Trichormus variabilis Anabaena sp.\; Anabaena variabilis (strain ATCC 29413 \/ PCC 7937) alr0039 Anabaena variabilis
artat-a1rb20 Arthrobacter aurescens (strain TC1) Putative epoxide hydrolase Arthrobacter aurescens
artoc-c5frz3 Arthroderma otae (strain CBS 113480) (Microsporum canis) Alpha\/beta hydrolase fold protein Arthroderma otae
azoc5-a8i6b5 Azorhizobium caulinodans (strain ATCC 43989 \/ DSM 5975 \/ ORS 571) Alpha\/beta hydrolase Azorhizobium caulinodans
azosb-a1k1f9 Azoarcus sp. (strain BH72) Haloacetate dehalogenase Azoarcus sp.
azovd-c1dng8 Azotobacter vinelandii (strain DJ \/ ATCC BAA-1303) Alpha\/beta hydrolase fold protein Azotobacter vinelandii
bacsk-q5wce1 Bacillus clausii (strain KSM-K16) hypothetical protein Bacillus clausii
beii9-b2ies6 Beijerinckia indica subsp. indica (strain ATCC 9039 \/ DSM 1715 \/ NCI 8712) Alpha\/beta hydrolase fold Beijerinckia indica subsp. indica
beii9-b2ii32 Beijerinckia indica subsp. indica (strain ATCC 9039 \/ DSM 1715 \/ NCI 8712) Alpha\/beta hydrolase fold Beijerinckia indica subsp. indica
borpd-a9ih03 Bordetella petrii (strain ATCC BAA-461 \/ DSM 12804 \/ CCUG 43448) Probable epoxide hydrolase Bordetella petrii
botfb-a6rr28 Botryotinia fuckeliana (strain B05.10) (Noble rot fungus) (Botrytis cinerea) Putative uncharacterized protein Botryotinia fuckeliana
braja-BLL7497 Bradyrhizobium japonicum bll7497 protein Bradyrhizobium japonicum
braja-BLR6965 Bradyrhizobium japonicum blr6965 protein Bradyrhizobium japonicum
braso-a4z0q9 Bradyrhizobium sp. (strain ORS278) Putative hydrolase Bradyrhizobium sp.
bura4-b1ynv1 Burkholderia ambifaria (strains MC40-6\; ATCC BAA-244 \/ AMMD) (Burkholderia cepacia) Alpha\/beta hydrolase fold protein Burkholderia ambifaria
burch-a0kd06 Burkholderia cenocepacia (strains HI2424\; AU 1054\; MC0-3\; PC184\; J2315 \/ LMG 16656) Burkholderia ambifaria AMMD Alpha\/beta hydrolase fold protein Burkholderia cenocepacia
burcj-b4e7m8 Burkholderia cepacia (strain J2315 \/ LMG 16656) (Burkholderia cenocepacia (strain J2315)) Putative hydrolase Burkholderia cepacia
burcj-b4e7p0 Burkholderia cepacia (strain J2315 \/ LMG 16656) (Burkholderia cenocepacia (strain J2315)) Putative hydrolase Burkholderia cepacia
burcj-b4e950 Burkholderia cepacia (strains J2315 \/ LMG 16656\; PC184\; AU 1054\; HI2424\; MC0-3) (Burkholderia cenocepacia) Putative hydrolase Burkholderia cepacia
burgb-c5aeb9 Burkholderia glumae (strain BGR1) Alpha\/beta hydrolase fold protein Burkholderia glumae
burm1-a9ak95 Burkholderia multivorans (strains ATCC 17616 \/ 249\; CGD1\; CGD2\; CGD2M) Haloacetate dehalogenase Burkholderia multivorans
burp8-b2jkg2 Burkholderia phymatum (strain DSM 17167 \/ STM815) Alpha\/beta hydrolase fold protein Burkholderia phymatum
burpp-b2swr4 Burkholderia phytofirmans (strain DSM 17436 \/ PsJN) Alpha\/beta hydrolase fold Burkholderia phytofirmans
burpp-b2sy47 Burkholderia phytofirmans (strain DSM 17436 \/ PsJN) Alpha\/beta hydrolase fold Burkholderia phytofirmans
burps-q63y59 Burkholderia pseudomallei (Pseudomonas pseudomallei), Burkholderia thailandensis putative hydrolase Burkholderia pseudomallei
bursp-deha Burkholderia sp Fluoroacetate dehalogenase Burkholderia sp.
burvg-a4jie1 Burkholderia vietnamiensis (strain G4 \/ LMG 22486) (Burkholderia cepacia (strain R1808)) Alpha\/beta hydrolase fold protein Burkholderia vietnamiensis
burvg-a4jmp7 Burkholderia vietnamiensis (strain G4 \/ LMG 22486) (Burkholderia cepacia (strain R1808))Alpha\/beta hydrolase fold protein Burkholderia vietnamiensis
burxl-q146l5 Burkholderia xenovorans (strain LB400) Putative hydrolase Burkholderia xenovorans
catad-c7py99 Catenulispora acidiphila (strain DSM 44928 \/ NRRL B-24433 \/ NBR 102108 \/ JCM 14897) Alpha\/beta hydrolase fold protein Catenulispora acidiphila
causk-b0t6k8 Caulobacter sp. (strain K31) Alpha\/beta hydrolase fold Caulobacter sp.
causk-b0t6q1 Caulobacter sp. (strain K31) Alpha\/beta hydrolase fold Caulobacter sp.
chlad-b8g5j1 Chloroflexus aggregans (strain MD-66 \/ DSM 9485) Alpha\/beta hydrolase fold protein Chloroflexus aggregans
chlsy-b9lky5 Chloroflexus aurantiacus (strains ATCC 29364 \/ DSM 637 \/ Y-400-fl\; ATCC 29366 \/ DSM 635 \/ J-10-fl) Alpha\/beta hydrolase fold protein Chloroflexus aurantiacus
chrsd-q1qtt6 Chromohalobacter salexigens (strain DSM 3043 \/ ATCC BAA-138 \/ NCIM 13768) alpha\/beta hydrolase Chromohalobacter salexigens
comte-b7x0f7 Comamonas testosteroni KF-1 Alpha\/beta hydrolase fold protein Comamonas testosteroni KF-1
conwi-d3f5c4 Conexibacter woesei (strain DSM 14684 \/ JCM 11494 \/ NBRC 100937 \/ ID131577) Alpha\/beta hydrolase fold protein Conexibacter woesei
cuppj-q476y6 Cupriavidus pinatubonensis (strain JMP134 \/ LMG 1197) (Alcaligenes eutrophus) (Ralstonia eutropha) alpha\/beta hydrolase fold Ralstonia eutropha
cuptr-b2agb4 Cupriavidus taiwanensis (Ralstonia taiwanensis), Cupriavidus necator (Ralstonia eutropha) Haloacetate dehalogenase Cupriavidus taiwanensis
cyaa5-b1wp98 Cyanothece sp. (strain ATCC 51142) Putative alpha\/beta hydrolase Cyanothece sp. ATCC 51142
cyap8-b7k4e0 Cyanothece sp. (strains PCC 8801\; 8802) (Synechococcus sp. (strains RF-1\; RF-2)) Alpha\/beta hydrolase fold protein Cyanothece sp. PCC 8801
decar-q479b8 Dechloromonas aromatica (strain RCB) haloacetate dehalogenase DAR3835 Dechloromonas aromatica
delas-a9blx5 Delftia acidovorans (strain DSM 14801 \/ SPH-1) Alpha\/beta hydrolase fold Delftia acidovorans
dinsh-a8lke2 Dinoroseobacter shibae (strain DFL 12) Haloacetate dehalogenase H-1 Dinoroseobacter shibae
emeni-q5bf92 Aspergillus nidulans FGSC A4 hypothetical protein Aspergillus nidulans FGSC A4
frasn-a8lgy1 Frankia sp. (strain EAN1pec) Alpha\/beta hydrolase fold Frankia sp.
geoog-d2say0 Geodermatophilus obscurus (strain ATCC 25078 \/ DSM 43160 \/ JCM 3152 \/ G-20) Alpha\/beta hydrolase fold protein Geodermatophilus obscurus
gibze-q4ihy5 Gibberella zeae (Fusarium graminearum) AB hydrolase-1 domain-containing protein Gibberella zeae
gluda-a9hiz2 Gluconacetobacter diazotrophicus (strain ATCC 49037 \/ DSM 5601 \/ PAl5) Putative hydrolase protein Gluconacetobacter diazotrophicus
herar-a4g378 Herminiimonas arsenicoxydans Haloacetate dehalogenase Herminiimonas arsenicoxydans
janma-a6t0i5 Janthinobacterium sp. (strain Marseille) (Minibacterium massiliensis) Hydrolase Janthinobacterium sp. Marseille
jansc-q28k13 Jannaschia sp. (strain CCS1) alpha\/beta hydrolase Jannaschia sp. CCS1
kocrd-b2gix1 Kocuria rhizophila (strain ATCC 9341 \/ DSM 348 \/ NBRC 103217 \/ DC2201) Putative hydrolase Kocuria rhizophila
krifd-d2px09 Kribbella flavida (strain DSM 17836 \/ JCM 10339 \/ NBRC 14399) Alpha\/beta hydrolase fold protein Kribbella flavida
krifd-d2q010 Kribbella flavida (strain DSM 17836 \/ JCM 10339 \/ NBRC 14399) Alpha\/beta hydrolase fold protein Kribbella flavida
krifd-d2q3l3 Kribbella flavida (strain DSM 17836 \/ JCM 10339 \/ NBRC 14399) Alpha\/beta hydrolase fold protein Kribbella flavida
lepcp-b1y135 Leptothrix cholodnii (strain ATCC 51168 \/ LMG 8142 \/ SP-6) (Leptothria discophora (strain SP-6)) Alpha\/beta hydrolase fold Leptothrix cholodnii
mago7-a4qwz1 Magnaporthe oryzae (strain 70-15 \/ FGSC 8958) (Rice blast fungus) (Pyricularia oryzae) Alpha\/beta hydrolase Magnaporthe oryzae
meslo-mlr1789 Mesorhizobium loti (Rhizobium loti) mlr1789 probable epoxide hydrolase Mesorhizobium loti
meslo-mlr9622 Mesorhizobium loti (Rhizobium loti) plasmid pMLb hydrolase mlr9622 gene Mesorhizobium loti
meted-c7ci36 Methylobacterium extorquens, (Methylobacterium dichloromethanicum)\; Methylorubrum extorquens, Putative alpha\/beta hydrolase, putative haloacetate dehalogenase Methylobacterium extorquens
metno-b8idj9 Methylobacterium nodulans (strain ORS2060 \/ LMG 21967) Alpha\/beta hydrolase fold protein Methylobacterium nodulans
metno-b8iid5 Methylobacterium nodulans (strain ORS2060 \/ LMG 21967) Alpha\/beta hydrolase fold protein Methylobacterium nodulans
metpb-b1zeq1 Methylobacterium populi (strain ATCC BAA-705 \/ NCIMB 13946 \/ BJ001) Alpha\/beta hydrolase fold Methylobacterium populi
metpp-a2sly3 Methylibium petroleiphilum (strain PM1) Putative hydrolase Methylibium petroleiphilum
metrj-b1m6j6 Methylobacterium radiotolerans (strain ATCC 27329 \/ DSM 1819 \/ JC 2831) Alpha\/beta hydrolase fold Methylobacterium radiotolerans
mets4-b0uls3 Methylobacterium sp. (strain 4-46) Alpha\/beta hydrolase fold Methylobacterium sp.
metsb-b8eqc0 Methylocella silvestris (strain BL2 \/ DSM 15510 \/ NCIMB 13906) Alpha\/beta hydrolase fold protein Methylocella silvestris
micae-a8yde8 Microcystis aeruginosa (strains PCC 7806\; NIES-843) Similar to tr|Q8Z0Q1|Q8Z0Q1 Microcystis aeruginosa
morsp-deh1 Moraxella sp. B Comamonas acidovorans plasmid dehH1 gene for haloacetate dehalogenase H-1, complete cds Moraxella sp.
mycs2-a0qtw0 Mycobacterium smegmatis (strain ATCC 700084 \/ mc(2)155) Haloacetate dehalogenase H-1 Mycobacterium smegmatis
mycs2-a0r6x8 Mycobacterium smegmatis (strain ATCC 700084 \/ mc(2)155) Epoxide hydrolase Mycobacterium smegmatis
nakmy-c8xb47 Nakamurella multipartita (strain ATCC 700099 \/ DSM 44233 \/ JCM 9543 \/ Y-104) (Microsphaera multipartita) Alpha\/beta hydrolase fold protein Nakamurella multipartita
nech7-c7z389 Nectria haematococca (strain 77-13-4 \/ FGSC 9596 \/ MPVI) (Fusarium solani subsp. pisi) Putative uncharacterized protein Nectria haematococca
neucr-q7s4j4 Neurospora crassa (strain ATCC 24698 \/ 74-OR23-1A \/ CBS 708.71 \/ DS 1257 \/ FGSC 987) Predicted protein Neurospora crassa
ocha4-a6x4z7 Ochrobactrum anthropi (strain ATCC 49188 \/ DSM 6882 \/ NCTC 12168) Alpha\/beta hydrolase fold Ochrobactrum anthropi
penmq-b6q3a3 Penicillium marneffei (strain ATCC 18224 \/ CBS 334.59 \/ QM 7333) Epoxide hydrolase, putative Penicillium marneffei
polna-a1vmr7 Polaromonas naphthalenivorans (strain CJ2) Alpha\/beta hydrolase fold protein Polaromonas naphthalenivorans
polsj-q123c8 Polaromonas sp. (strain JS666 \/ ATCC BAA-500) Alpha\/beta hydrolase fold protein Polaromonas sp.
polsj-q128r1 Polaromonas sp. (strain JS666 \/ ATCC BAA-500) Alpha\/beta hydrolase fold protein Polaromonas sp.
polsq-a4sxi5 Polynucleobacter sp. (strain QLW-P1DMWA-1) Alpha\/beta hydrolase fold protein Polynucleobacter sp.
pseae-PA2086 Pseudomonas aeruginosa (strains PA01\; C3719\; LESB58\; 2192\; UCBPP-PA14) PA2086 Pseudomonas aeruginosa
psef5-q4k7i6 Pseudomonas fluorescens (strain Pf-5 \/ ATCC BAA-477) hydrolase, alpha\/beta fold family Pseudomonas fluorescens
psefs-c3k927 Pseudomonas fluorescens (strain SBW25) Putative hydrolase Pseudomonas fluorescens
psepf-q3k995 Pseudomonas fluorescens (strain PfO-1) alpha\/beta hydrolase fold Pseudomonas fluorescens
psyin-a1swh1 Psychromonas ingrahamii (strain 37) Alpha\/beta hydrolase fold protein Psychromonas ingrahamii
ralme-q1lry8 Ralstonia metallidurans (strain CH34 \/ ATCC 43123 \/ DSM 2839) alpha\/beta hydrolase fold Ralstonia metallidurans
ralme-q1ls61 Ralstonia metallidurans (strain CH34 \/ ATCC 43123 \/ DSM 2839) alpha\/beta hydrolase fold Ralstonia metallidurans
ralpj-b2ud82 Ralstonia pickettii (strains 12J\; 12D) Alpha\/beta hydrolase fold Ralstonia pickettii
ralso-DEHH Ralstonia solanacearum (Pseudomonas solanacearum)(and strain IPO1609\; UW551) (EC 3.8.1.3) Ralstonia solanacearum
rensm-a9wpl6 Renibacterium salmoninarum (strain ATCC 33209 \/ DSM 20767 \/ JCM 1148 \/ NBRC 15589 \/ NCIMB 2235) Haloacetate dehalogenase H-1 Renibacterium salmoninarum
rhie6-b3q494 Rhizobium etli (strain CIAT 652) Putative epoxide hydrolase protein Rhizobium etli
rhie6-b3q5q8 Rhizobium etli (strain CIAT 652) Putative hydrolase protein Rhizobium etli
rhiec-q2jz28 Rhizobium etli (strain CFN 42 \/ ATCC 51251) putative hydrolase protein Rhizobium etli
rhils-c6b5g1 Rhizobium leguminosarum bv. trifolii (strain WSM1325) Alpha\/beta hydrolase fold protein Rhizobium leguminosarum bv. trifolii
rhilw-b5znq7 Rhizobium leguminosarum bv. trifolii (strain WSM2304) Hydrolase or acyltransferase (Alpha\/beta hydrolase superfamily)-like protein Rhizobium leguminosarum bv. trifolii
rhilw-b6a1f4 Rhizobium leguminosarum bv. trifolii (strain WSM2304) Alpha\/beta hydrolase fold Rhizobium leguminosarum bv. trifolii
rhoe4-c0ztz5 Rhodococcus erythropolis (strains PR4 \/ NBRC 100887\; SK121) Hydrolase Rhodococcus erythropolis
rhop2-q2iyy8 Rhodopseudomonas palustris (strain HaA2) alpha\/beta hydrolase Rhodopseudomonas palustris
rhopa-q6nam1 Rhodopseudomonas palustris (and strains BisB5\; TIE-1) RPA1163 possible epoxide hydrolase Rhodopseudomonas palustris
rhops-q131b7 Rhodopseudomonas palustris (strain BisB5) Alpha\/beta hydrolase fold Rhodopseudomonas palustris
rhosk-b9kl36 Rhodobacter sphaeroides (strain KD131 \/ KCTC 12085) Hydrolase, alpha\/beta fold family Rhodobacter sphaeroides
roscs-a7ni12 Roseiflexus castenholzii (strain DSM 13941 \/ HLO8) Alpha\/beta hydrolase fold Roseiflexus castenholzii
rosdo-q165i6 Roseobacter denitrificans (strain ATCC 33942 \/ OCh 114) (Erythrobacter sp. (strain OCh 114)) (Roseobacter denitrificans) Haloacetate dehalogenase H-1, putative Roseobacter denitrificans
ross1-a5uzx3 Roseiflexus sp. (strain RS-1) Alpha\/beta hydrolase fold Roseiflexus sp. RS-1
sacen-a4fbt1 Saccharopolyspora erythraea (strain NRRL 23338) Alpha\/beta hydrolase fold Saccharopolyspora erythraea
sacen-a4fdk1 Saccharopolyspora erythraea (strain NRRL 23338) Probable epoxide alpha\/beta hydrolase Saccharopolyspora erythraea
salty-STM0332 Salmonella typhimurium, Salmonella paratyphi, S. choleraesuis, S. enteritidis, S. enterica, S. agona, S. newport, S. dublin, S. gallinarum, putative hydrolase or acyltransferase Salmonella typhimurium
scls1-a7e7d3 Sclerotinia sclerotiorum (strain ATCC 18683 \/ 1980 \/ Ss-1) (White mold) (Whetzelinia sclerotiorum) Putative uncharacterized protein Sclerotinia sclerotiorum
serod-d4e6t6 Serratia odorifera DSM 4582 Haloacetate dehalogenase H-1 Serratia odorifera DSM 4582
sormk-d1z8p7 Sordaria macrospora (strain ATCC MYA-333 \/ DSM 997 \/ K(L3346) (K-hell) Whole genome shotgun sequence assembly, scaffold_9 Sordaria macrospora
stanl-d3pve8 Stackebrandtia nassauensis (strain DSM 44728 \/ NRRL B-16338 \/ NBR 102104 \/ LLR-40K-21) Alpha\/beta hydrolase fold protein Stackebrandtia nassauensis
stanl-d3q3r4 Stackebrandtia nassauensis (strain DSM 44728 \/ NRRL B-16338 \/ NBR 102104 \/ LLR-40K-21) Alpha\/beta hydrolase fold protein Stackebrandtia nassauensis
strcl-b5gw27 Streptomyces clavuligerus ATCC 27064 Alpha\/beta hydrolase fold-containing protein Streptomyces clavuligerus ATCC 27064
strco-SC2H12.04 Streptomyces coelicolor SC2H12.04 Streptomyces coelicolor
strco-SCM1.32 Streptomyces coelicolor SCM1.32 putative hydrolase Streptomyces coelicolor
strfr-q45rb2 Streptomyces fradiae probable hydrolase Streptomyces fradiae
strgg-b1vmn5 Streptomyces griseus subsp. griseus (strain JCM 4626 \/ NBRC 13350) Putative hydrolase Streptomyces griseus subsp. griseus
strpr-b5hjj3 Streptomyces pristinaespiralis ATCC 25486 Hydrolase Streptomyces pristinaespiralis ATCC 25486
strrd-d2bc04 Streptosporangium roseum (strain ATCC 12428 \/ DSM 43021 \/ JCM 3005 \/ NI 9100)Haloacetate dehalogenase Streptosporangium roseum
strrd-d2bdt5 Streptosporangium roseum (strain ATCC 12428 \/ DSM 43021 \/ JCM 3005 \/ NI 9100) Alpha\/beta fold family hydrolase Streptosporangium roseum
talsn-b8lt59 Talaromyces stipitatus (strain ATCC 10500 \/ CBS 375.48 \/ QM 6759 \/ NRRL 1006) (Penicillium stipitatum) Epoxide hydrolase, putative Talaromyces stipitatus
uncre-c4jnn3 Uncinocarpus reesii (strain UAMH 1704) Predicted protein Uncinocarpus reesii
varps-c5cuk9 Variovorax paradoxus (strain S110) Alpha\/beta hydrolase fold protein Variovorax paradoxus
xanp2-a7ijy4 Xanthobacter autotrophicus (strain ATCC BAA-1158 \/ Py2) Alpha\/beta hydrolase fold Xanthobacter autotrophicus

Gene_locus_frgt Name Species
9chro-a3iqm5 Cyanothece sp. CCY0110 Putative hydrolase Cyanothece sp. CCY0110
crowt-q4c9b6 Crocosphaera watsonii haloacetate dehalogenase (EC 3.8.1.3) Crocosphaera watsonii

Substrate Chemical Nomenclature Proteins
Bromoacetate 2-bromoacetate\ rhopa-q6nam1
Chloroacetate 2-chloroacetate rhopa-q6nam1
DHA 2,2-dihydroxyacetic acid decar-q479b8
Difluoroacetate 2,2-difluoroacetic acid decar-q479b8
Fluoroacetate 2-fluoroacetate pseae-PA2086

Inhibitor Chemical Nomenclature Proteins
Glycolate 2-hydroxyacetic acid rhopa-q6nam1

References (2)

Title : X-Ray crystallographic and mutational studies of fluoroacetate dehalogenase from Burkholderia sp. strain FA1 - Jitsumori_2009_J.Bacteriol_191_2630
Author(s) : Jitsumori K , Omi R , Kurihara T , Kurata A , Mihara H , Miyahara I , Hirotsu K , Esaki N
Ref : Journal of Bacteriology , 191 :2630 , 2009
Abstract :
PubMedSearch : Jitsumori_2009_J.Bacteriol_191_2630
PubMedID: 19218394
Gene_locus related to this paper: bursp-deha

Title : Diversity and biocatalytic potential of epoxide hydrolases identified by genome analysis - van Loo_2006_Appl.Environ.Microbiol_72_2905
Author(s) : van Loo B , Kingma J , Arand M , Wubbolts MG , Janssen DB
Ref : Applied Environmental Microbiology , 72 :2905 , 2006
Abstract :
PubMedSearch : van Loo_2006_Appl.Environ.Microbiol_72_2905
PubMedID: 16597997
Gene_locus related to this paper: agrra-echA , bacsu-yfhM , corsp-cEH , deira-DR2549 , myctu-ephF , nosp7-b2j4w6 , nosp7-b2iv02 , psepu-PP4624 , rhopa-q6n645 , strco-2SCG4.13 , thefy-q47qj2