NBD-HE-HP

ABPP-Probe labels many serine hydrolases and not only alpha/beta hydrolases . Compound XXX1 in Oskolkova_2003_Chem.Phys.Lipids_125_103

General

Type : Organophosphate, ABPP-Probe, NBD-nitro-benzoxadiazol-fluorescent, pNP, Benzoxadiazole

Chemical_Nomenclature : N-[2-[hexyl-(4-nitrophenoxy)phosphoryl]oxyethyl]-6-[(4-nitro-2,1,3-benzoxadiazol-7-yl)amino]hexanamide

Canonical SMILES : CCCCCCP(=O)(OCCNC(=O)CCCCCNC1=CC=C(C2=NON=C12)[N+](=O)[O-])OC3=CC=C(C=C3)[N+](=O)[O-]

InChI : InChI=1S\/C26H35N6O9P\/c1-2-3-4-8-19-42(38,40-21-12-10-20(11-13-21)31(34)35)39-18-17-28-24(33)9-6-5-7-16-27-22-14-15-23(32(36)37)26-25(22)29-41-30-26\/h10-15,27H,2-9,16-19H2,1H3,(H,28,33)

InChIKey : ZFHHVTNYROZCIO-UHFFFAOYSA-N

Other name(s) : AC1LD8L8  ||  SCHEMBL13199489  ||  LP106166  ||  2-{6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]hexaneamido}ethyl 4-nitrophenyl hexylphosphonate  ||  689264-29-7  ||  N-[2-[hexyl-(4-nitrophenoxy)phosphoryl]oxyethyl]-6-[(4-nitro-2,1,3-benzoxadiazol-7-yl)amino]hexanamide  ||  (O-((6-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)hexanoyl)aminoethyl-O-(n-hexyl)phosphonic acid p-nitrophenyl ester


MW : 606.56

Formula : C26H35N6O9P

CAS_number :

PubChem : 644117

UniChem : ZFHHVTNYROZCIO-UHFFFAOYSA-N

References (5)

Title : Functional fat body proteomics and gene targeting reveal in vivo functions of Drosophila melanogaster a-Esterase-7 - Birner-Gruenberger_2012_Insect.Biochem.Mol.Biol_42_220
Author(s) : Birner-Gruenberger R , Bickmeyer I , Lange J , Hehlert P , Hermetter A , Kollroser M , Rechberger GN , Kuhnlein RP
Ref : Insect Biochemistry & Molecular Biology , 42 :220 , 2012
Abstract :
PubMedSearch : Birner-Gruenberger_2012_Insect.Biochem.Mol.Biol_42_220
PubMedID: 22198472
Gene_locus related to this paper: drome-aes02 , drome-aes05 , drome-CG1882 , drome-CG2059 , drome-CG5355 , drome-CG8425 , drome-CG18815 , drome-EST23aes07 , drome-este6

Title : Functional proteomic analysis of lipases and esterases in cultured human adipocytes - Schicher_2010_J.Proteome.Res_9_6334
Author(s) : Schicher M , Morak M , Birner-Gruenberger R , Kayer H , Stojcic B , Rechberger G , Kollroser M , Hermetter A
Ref : J Proteome Res , 9 :6334 , 2010
Abstract :
PubMedSearch : Schicher_2010_J.Proteome.Res_9_6334
PubMedID: 20942458

Title : Novel fluorescent phosphonic acid esters for discrimination of lipases and esterases - Schmidinger_2005_Chembiochem_6_1776
Author(s) : Schmidinger H , Birner-Gruenberger R , Riesenhuber G , Saf R , Susani-Etzerodt H , Hermetter A
Ref : Chembiochem , 6 :1776 , 2005
Abstract :
PubMedSearch : Schmidinger_2005_Chembiochem_6_1776
PubMedID: 16094692

Title : The lipolytic proteome of mouse adipose tissue - Birner-Gruenberger_2005_Mol.Cell.Proteomics_4_1710
Author(s) : Birner-Gruenberger R , Susani-Etzerodt H , Waldhuber M , Riesenhuber G , Schmidinger H , Rechberger G , Kollroser M , Strauss JG , Lass A , Zimmermann R , Haemmerle G , Zechner R , Hermetter A
Ref : Mol Cell Proteomics , 4 :1710 , 2005
Abstract :
PubMedSearch : Birner-Gruenberger_2005_Mol.Cell.Proteomics_4_1710
PubMedID: 16048907

Title : Fluorescent organophosphonates as inhibitors of microbial lipases - Oskolkova_2003_Chem.Phys.Lipids_125_103
Author(s) : Oskolkova OV , Saf R , Zenzmaier E , Hermetter A
Ref : Chemistry & Physic of Lipids , 125 :103 , 2003
Abstract :
PubMedSearch : Oskolkova_2003_Chem.Phys.Lipids_125_103
PubMedID: 14499469