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Azaspiro

General

Nitrogen containing spirocycles represent a very important class of building blocks in many natural products and pharmaceutical drugs
Inhibitor Main targeted enzyme families Type Structure
MGLL-BODIPY-Cpd5 Monoglyceridelipase_lysophospholip Azaspiro BODIPY-derivative Boron compound
MGLL-BODIPY-Cpd9 Monoglyceridelipase_lysophospholip Azaspiro BODIPY-derivative Boron compound
MGLL-IN-Cpd118 Monoglyceridelipase_lysophospholip Triazol Azaspiro Trifluoro Pyrazole
spiro-b-lactam-pyrroloquinoline-6b S9N_PPCE_Peptidase_S9 Azaspiro beta-Lactam Pyrrolidine Quinoline
SCHEMBL19582562 ABHD6-Lip Morpholine Carbamate Trifluoro Azaspiro
CHEMBL3908555 PAF-Acetylhydrolase Azaspiro
Z3J-Cmpd6-7M7V Thioesterase Carboxamide Benzofuran Azaspiro
MAGL-2305 Monoglyceridelipase_lysophospholip PET probe Piperidine Azaspiro
SCHEMBL19421119 Monoglyceridelipase_lysophospholip Azaspiro Azetidin
SCHEMBL19421059 Monoglyceridelipase_lysophospholip Azaspiro Piperidine
LK864 Epoxide_hydrolase Azaspiro Sulfur Compound Sulfonyl Urea derivative Trifluoro