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staau-SAV0446

Staphylococcus aureus TslA SAOUHSC_00406 type VII-secreted lipase toxin

Comment

There are more than 1000 strains. Other Uniprot entries and list of strains can be found with the link: Other strains

Relationship

Family : T7SS-TslA

Block : X

Position in NCBI Life Tree : Staphylococcus aureus

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Bacteria N E > Terrabacteria group N E > Firmicutes N E > Bacilli N E > Bacillales N E > Staphylococcaceae N E > Staphylococcus N E > Staphylococcus aureus N E

Molecular evidence

No mutation

No structure

No kinetic

No disease

No substrate

No inhibitor

Database

Sequence

Peptide

MLSRKYKIDL KAINQNTEST SAISKASYEV ENANNNGLSK RDVINQFNDL KKMKKFPSNL EYVDSYTDSL TGVTTSAFLN KDTGKVTLGM TGTNLQDEAF KKLKEGEFSR QNVTNALETV KDGYADLKIL YSPASDQNYR YANTQEFINK IKSKYDIDFI TGHSLGGRDA VVLGMSNGIP NIVVYNPAPI SITSLNPNSP DGKRLLELYK NYKGNITRFV AENDALTENL KKYKHYVFFG NDKVFKNGKG HEMEGFLTEE EQKAIKKELK KLQGYAEENN KSFVKNSNNA ISKLASIELL RANMMTTNGG GLSSSQQKVL ESLTALTIAQ SFSQLIDDEI NQIKKMYNEK KKKFGKNWED AQKAGKAVGE DLSVNGVLNA LDEGQVNESS MVREPEQMIS AKERQLSTIG SSVSNYIMRV RLSINEIVDK DQVLASQIGG LL

References (12)

Title : A type VII-secreted lipase toxin with reverse domain arrangement - Garrett_2023_Nat.Commun_14_8438
Author(s) : Garrett SR , Mietrach N , Deme J , Bitzer A , Yang Y , Ulhuq FR , Kretschmer D , Heilbronner S , Smith TK , Lea SM , Palmer T
Ref : Nat Commun , 14 :8438 , 2023
Abstract :
PubMedSearch : Garrett_2023_Nat.Commun_14_8438
PubMedID: 38114483
Gene_locus related to this paper: staau-SAV0446

Title : Whole genome analysis of a livestock-associated methicillin-resistant Staphylococcus aureus ST398 isolate from a case of human endocarditis - Schijffelen_2010_BMC.Genomics_11_376
Author(s) : Schijffelen MJ , Boel CH , van Strijp JA , Fluit AC
Ref : BMC Genomics , 11 :376 , 2010
Abstract :
PubMedSearch : Schijffelen_2010_BMC.Genomics_11_376
PubMedID: 20546576
Gene_locus related to this paper: staau-c8mfq3 , staau-LIP , staau-lipas , staau-MW0741 , staau-MW2456 , staau-q6gfm6 , staau-SA0011 , staau-SA0569 , staau-SA0572 , staau-SA0897 , staau-SA1143 , staau-SA2240 , staau-SA2306 , staau-SA2367 , staau-SA2422 , staau-SAV0321 , staau-SAV0446 , staau-SAV0457 , staau-SAV0655 , staau-SAV1014 , staau-SAV1765 , staau-SAV1793 , staau-SAV2188 , staau-SAV2350 , staau-SAV2594

Title : Genome sequence of a recently emerged, highly transmissible, multi-antibiotic- and antiseptic-resistant variant of methicillin-resistant Staphylococcus aureus, sequence type 239 (TW) - Holden_2010_J.Bacteriol_192_888
Author(s) : Holden MT , Lindsay JA , Corton C , Quail MA , Cockfield JD , Pathak S , Batra R , Parkhill J , Bentley SD , Edgeworth JD
Ref : Journal of Bacteriology , 192 :888 , 2010
Abstract :
PubMedSearch : Holden_2010_J.Bacteriol_192_888
PubMedID: 19948800
Gene_locus related to this paper: staau-LIP , staau-MW0741 , staau-MW2456 , staau-q6gfm6 , staau-SA0569 , staau-SA0572 , staau-SA0897 , staau-SA1143 , staau-SA2240 , staau-SA2306 , staau-SA2422 , staau-SAV0321 , staau-SAV0446 , staau-SAV0457 , staau-SAV0655 , staau-SAV1014 , staau-SAV1765 , staau-SAV1793 , staau-SAV2188 , staau-SAV2350 , staau-SAV2594

Title : Genome sequencing and analysis reveals possible determinants of Staphylococcus aureus nasal carriage - Sivaraman_2008_BMC.Genomics_9_433
Author(s) : Sivaraman K , Venkataraman N , Tsai J , Dewell S , Cole AM
Ref : BMC Genomics , 9 :433 , 2008
Abstract :
PubMedSearch : Sivaraman_2008_BMC.Genomics_9_433
PubMedID: 18808706
Gene_locus related to this paper: staau-lipas , staau-MW0741 , staau-q6gfm6 , staau-SA0011 , staau-SA0569 , staau-SA0572 , staau-SA0897 , staau-SA1143 , staau-SA2240 , staau-SA2306 , staau-SA2367 , staau-SA2422 , staau-SAV0321 , staau-SAV0446 , staau-SAV0457 , staau-SAV0655 , staau-SAV1014 , staau-SAV1765 , staau-SAV1793 , staau-SAV2188 , staau-SAV2350 , staau-SAV2594

Title : Mutated response regulator graR is responsible for phenotypic conversion of Staphylococcus aureus from heterogeneous vancomycin-intermediate resistance to vancomycin-intermediate resistance - Neoh_2008_Antimicrob.Agents.Chemother_52_45
Author(s) : Neoh HM , Cui L , Yuzawa H , Takeuchi F , Matsuo M , Hiramatsu K
Ref : Antimicrobial Agents & Chemotherapy , 52 :45 , 2008
Abstract :
PubMedSearch : Neoh_2008_Antimicrob.Agents.Chemother_52_45
PubMedID: 17954695
Gene_locus related to this paper: staau-LIP , staau-lipas , staau-MW0741 , staau-MW2456 , staau-q6gfm6 , staau-SA0011 , staau-SA0569 , staau-SA0572 , staau-SA0897 , staau-SA1143 , staau-SA2240 , staau-SA2306 , staau-SA2367 , staau-SA2422 , staau-SAV0321 , staau-SAV0446 , staau-SAV0457 , staau-SAV0655 , staau-SAV1014 , staau-SAV1765 , staau-SAV1793 , staau-SAV2188 , staau-SAV2350 , staau-SAV2484 , staau-SAV2594

Title : Genome sequence of Staphylococcus aureus strain Newman and comparative analysis of staphylococcal genomes: polymorphism and evolution of two major pathogenicity islands - Baba_2008_J.Bacteriol_190_300
Author(s) : Baba T , Bae T , Schneewind O , Takeuchi F , Hiramatsu K
Ref : Journal of Bacteriology , 190 :300 , 2008
Abstract :
PubMedSearch : Baba_2008_J.Bacteriol_190_300
PubMedID: 17951380
Gene_locus related to this paper: staau-LIP , staau-lipas , staau-MW0741 , staau-MW2456 , staau-q6gfm6 , staau-SA0011 , staau-SA0569 , staau-SA0572 , staau-SA0897 , staau-SA1143 , staau-SA2306 , staau-SA2367 , staau-SA2422 , staau-SAV0321 , staau-SAV0446 , staau-SAV0457 , staau-SAV0655 , staau-SAV1014 , staau-SAV1765 , staau-SAV1793 , staau-SAV2188 , staau-SAV2350 , staau-SAV2484 , staau-SAV2594

Title : Subtle genetic changes enhance virulence of methicillin resistant and sensitive Staphylococcus aureus - Highlander_2007_BMC.Microbiol_7_99
Author(s) : Highlander SK , Hulten KG , Qin X , Jiang H , Yerrapragada S , Mason EO, Jr. , Shang Y , Williams TM , Fortunov RM , Liu Y , Igboeli O , Petrosino J , Tirumalai M , Uzman A , Fox GE , Cardenas AM , Muzny DM , Hemphill L , Ding Y , Dugan S , Blyth PR , Buhay CJ , Dinh HH , Hawes AC , Holder M , Kovar CL , Lee SL , Liu W , Nazareth LV , Wang Q , Zhou J , Kaplan SL , Weinstock GM
Ref : BMC Microbiol , 7 :99 , 2007
Abstract :
PubMedSearch : Highlander_2007_BMC.Microbiol_7_99
PubMedID: 17986343
Gene_locus related to this paper: staa3-q2fkj0 , staau-LIP , staau-lipas , staau-MW0741 , staau-MW2456 , staau-q6gfm6 , staau-SA0011 , staau-SA0569 , staau-SA0572 , staau-SA0897 , staau-SA1143 , staau-SA2240 , staau-SA2306 , staau-SA2367 , staau-SA2422 , staau-SAV0321 , staau-SAV0446 , staau-SAV0457 , staau-SAV0655 , staau-SAV1014 , staau-SAV1765 , staau-SAV1793 , staau-SAV2188 , staau-SAV2350 , staau-SAV2594

Title : Complete genome sequence of USA300, an epidemic clone of community-acquired meticillin-resistant Staphylococcus aureus - Diep_2006_Lancet_367_731
Author(s) : Diep BA , Gill SR , Chang RF , Phan TH , Chen JH , Davidson MG , Lin F , Lin J , Carleton HA , Mongodin EF , Sensabaugh GF , Perdreau-Remington F
Ref : Lancet , 367 :731 , 2006
Abstract :
PubMedSearch : Diep_2006_Lancet_367_731
PubMedID: 16517273
Gene_locus related to this paper: staa3-q2fkj0 , staau-LIP , staau-lipas , staau-MW0741 , staau-MW2456 , staau-q6gfm6 , staau-SA0011 , staau-SA0569 , staau-SA0572 , staau-SA0897 , staau-SA1143 , staau-SA2240 , staau-SA2306 , staau-SA2367 , staau-SA2422 , staau-SAV0321 , staau-SAV0446 , staau-SAV0457 , staau-SAV0655 , staau-SAV1014 , staau-SAV1765 , staau-SAV1793 , staau-SAV2188 , staau-SAV2350 , staau-SAV2594

Title : Insights on evolution of virulence and resistance from the complete genome analysis of an early methicillin-resistant Staphylococcus aureus strain and a biofilm-producing methicillin-resistant Staphylococcus epidermidis strain - Gill_2005_J.Bacteriol_187_2426
Author(s) : Gill SR , Fouts DE , Archer GL , Mongodin EF , DeBoy RT , Ravel J , Paulsen IT , Kolonay JF , Brinkac L , Beanan M , Dodson RJ , Daugherty SC , Madupu R , Angiuoli SV , Durkin AS , Haft DH , Vamathevan J , Khouri H , Utterback T , Lee C , Dimitrov G , Jiang L , Qin H , Weidman J , Tran K , Kang K , Hance IR , Nelson KE , Fraser CM
Ref : Journal of Bacteriology , 187 :2426 , 2005
Abstract :
PubMedSearch : Gill_2005_J.Bacteriol_187_2426
PubMedID: 15774886
Gene_locus related to this paper: staau-LIP , staau-lipas , staau-MW0741 , staau-MW2456 , staau-q6gfm6 , staau-SA0011 , staau-SA0569 , staau-SA0572 , staau-SA0897 , staau-SA1143 , staau-SA2240 , staau-SA2306 , staau-SA2367 , staau-SA2422 , staau-SAV0321 , staau-SAV0446 , staau-SAV0457 , staau-SAV0655 , staau-SAV1014 , staau-SAV1765 , staau-SAV1793 , staau-SAV2188 , staau-SAV2350 , staau-SAV2484 , staau-SAV2594 , staep-lipas , staep-SE0011 , staep-SE0226 , staep-SE0386 , staep-SE0389 , staep-SE0424 , staep-SE0564 , staep-SE0714 , staep-SE0745 , staep-SE0980 , staep-SE1436 , staep-SE1460 , staep-SE1510 , staep-SE1780 , staep-SE1929 , staep-SERP2035 , staep-SE2050 , staep-SE2095 , staep-SE2213 , staep-SE2328

Title : Complete genomes of two clinical Staphylococcus aureus strains: evidence for the rapid evolution of virulence and drug resistance - Holden_2004_Proc.Natl.Acad.Sci.U.S.A_101_9786
Author(s) : Holden MT , Feil EJ , Lindsay JA , Peacock SJ , Day NP , Enright MC , Foster TJ , Moore CE , Hurst L , Atkin R , Barron A , Bason N , Bentley SD , Chillingworth C , Chillingworth T , Churcher C , Clark L , Corton C , Cronin A , Doggett J , Dowd L , Feltwell T , Hance Z , Harris B , Hauser H , Holroyd S , Jagels K , James KD , Lennard N , Line A , Mayes R , Moule S , Mungall K , Ormond D , Quail MA , Rabbinowitsch E , Rutherford K , Sanders M , Sharp S , Simmonds M , Stevens K , Whitehead S , Barrell BG , Spratt BG , Parkhill J
Ref : Proc Natl Acad Sci U S A , 101 :9786 , 2004
Abstract :
PubMedSearch : Holden_2004_Proc.Natl.Acad.Sci.U.S.A_101_9786
PubMedID: 15213324
Gene_locus related to this paper: staau-d2feb3 , staau-d2uin3 , staau-LIP , staau-lipas , staau-MW0741 , staau-MW2456 , staau-q6gfm6 , staau-SA0011 , staau-SA0569 , staau-SA0572 , staau-SA0897 , staau-SA1143 , staau-SA2240 , staau-SA2306 , staau-SA2367 , staau-SA2422 , staau-SAV0321 , staau-SAV0446 , staau-SAV0457 , staau-SAV0655 , staau-SAV1014 , staau-SAV1765 , staau-SAV1793 , staau-SAV2188 , staau-SAV2350 , staau-SAV2594

Title : Genome and virulence determinants of high virulence community-acquired MRSA - Baba_2002_Lancet_359_1819
Author(s) : Baba T , Takeuchi F , Kuroda M , Yuzawa H , Aoki K , Oguchi A , Nagai Y , Iwama N , Asano K , Naimi T , Kuroda H , Cui L , Yamamoto K , Hiramatsu K
Ref : Lancet , 359 :1819 , 2002
Abstract :
PubMedSearch : Baba_2002_Lancet_359_1819
PubMedID: 12044378
Gene_locus related to this paper: staau-d2uin3 , staau-LIP , staau-lipas , staau-MW0741 , staau-MW2456 , staau-q6gfm6 , staau-SA0011 , staau-SA0569 , staau-SA0572 , staau-SA0897 , staau-SA1143 , staau-SA2240 , staau-SA2306 , staau-SA2367 , staau-SA2422 , staau-SAV0321 , staau-SAV0446 , staau-SAV0457 , staau-SAV0655 , staau-SAV1014 , staau-SAV1765 , staau-SAV1793 , staau-SAV2188 , staau-SAV2350

Title : Whole genome sequencing of meticillin-resistant Staphylococcus aureus - Kuroda_2001_Lancet_357_1225
Author(s) : Kuroda M , Ohta T , Uchiyama I , Baba T , Yuzawa H , Kobayashi I , Cui L , Oguchi A , Aoki K , Nagai Y , Lian J , Ito T , Kanamori M , Matsumaru H , Maruyama A , Murakami H , Hosoyama A , Mizutani-Ui Y , Takahashi NK , Sawano T , Inoue R , Kaito C , Sekimizu K , Hirakawa H , Kuhara S , Goto S , Yabuzaki J , Kanehisa M , Yamashita A , Oshima K , Furuya K , Yoshino C , Shiba T , Hattori M , Ogasawara N , Hayashi H , Hiramatsu K
Ref : Lancet , 357 :1225 , 2001
Abstract :
PubMedSearch : Kuroda_2001_Lancet_357_1225
PubMedID: 11418146
Gene_locus related to this paper: staau-LIP , staau-lipas , staau-MW0741 , staau-MW2456 , staau-q6gfm6 , staau-SA0011 , staau-SA0569 , staau-SA0572 , staau-SA0897 , staau-SA1143 , staau-SA2240 , staau-SA2306 , staau-SA2367 , staau-SA2422 , staau-SAV0321 , staau-SAV0446 , staau-SAV0457 , staau-SAV0655 , staau-SAV1014 , staau-SAV1765 , staau-SAV1793 , staau-SAV2188 , staau-SAV2350 , staau-SAV2484 , staau-SAV2594