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ABHD10

Relationship

Family: ABHD10

Block: X

Parent Family: Hydrolase_4

Comment

Abhydrolase domain-containing protein 10, Mycophenolic acid acyl-glucuronide esterase, mitochondrial. Mycophenolic acid (MPA), the active metabolite of the immunosuppressant mycophenolate mofetil (MMF), is primarily metabolized by glucuronidation to a phenolic glucuronide (MPAG) and an acyl glucuronide (AcMPAG Mycophenolic-acid-acyl-glucuronide). AcMPAG, may be an immunotoxic, and is deglucuronidated by ABBHD10. ABHD10 is an S-depalmitoylase affecting redox homeostasis through peroxiredoxin-5 (Cao et al.). The name of this family should not be confounded with family Abhydrolase_10 which is quite far related and contains only sequences from bacteria and fungi

Database

Interpro : No interpro

PIRSF : No PIRSF

Pdoc : No Pdoc

Pfam : No Pfam

Prints : No Print

EC Number : No EC Number

Sequences

Peptide in Fasta
Nucleotide in Fasta
Alignment with Multalin Text only
Seed alignment with MAFFT No colour / coloured with Mview
Alignment with MAFFT No colour / coloured with Mview
Dendrogram The dnd file

Structure Name Proteins
6NY9 Alpha\/beta hydrolase domain-containing protein 10 from mouse mouse-abhda

Gene_locus Name Species
bovin-ABHDA Bos taurus (Bovine)\; Bos mutus (wild yak) abhydrolase domain containing 10 Bos taurus
danre-ABHD10a Danio rerio (Zebrafish) (Brachydanio rerio) Abhydrolase domain-containing 10a (abhd10) Danio rerio
danre-ABHD10b Danio rerio (Zebrafish) (Brachydanio rerio). Uncharacterized protein ABHD10b Danio rerio
human-ABHD10 Homo sapiens (Human) ABHDA ABHD10 Abhydrolase domain-containing protein 10, Mycophenolic acid acyl-glucuronide esterase, S-depalmitoylase of peroxiredoxin-5, mitochondrial Homo sapiens
mouse-abhda Mus musculus (Mouse) Abhydrolase domain-containing protein 10, mitochondrial Mus musculus
ponab-abhda Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) Alpha\/beta hydrolase domain-containing protein 10 Pongo abelii
rat-abhda Rattus norvegicus (Rat) Abhydrolase domain-containing protein 10, mitochondrial Rattus norvegicus
tetng-q4s578 Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon nigroviridis) chromosome 6 scaf14737, whole genome shotgun sequence Tetraodon nigroviridis
panpa-a0a2r8zvr0 Pan paniscus (Pygmy chimpanzee) (Bonobo). Abhydrolase domain containing 10 Pan paniscus
pantr-h2qn34 Pan troglodytes (Chimpanzee). Abhydrolase domain containing 10 Pan troglodytes
gorgo-g3rhg1 Gorilla gorilla gorilla (Western lowland gorilla). Abhydrolase domain containing 10 Gorilla gorilla gorilla
nomle-a0a2i3gyd4 Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys). Abhydrolase domain containing 10 Nomascus leucogenys
macne-a0a2k6avf3 Macaca nemestrina (Pig-tailed macaque). Abhydrolase domain containing 10 Macaca nemestrina
macfa-a0a2k5wkd0 Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey). Abhydrolase domain containing 10 Macaca fascicularis
manle-a0a2k5ypx1 Mandrillus leucophaeus (Drill) (Papio leucophaeus). Abhydrolase domain containing 10 Mandrillus leucophaeus
cerat-a0a2k5me28 Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys). Abhydrolase domain containing 10 Cercocebus atys
macmu-h9zaw9 Macaca mulatta (Rhesus macaque). Abhydrolase domain-containing protein 10, mitochondrial Macaca mulatta
papan-a0a096ms98 Papio anubis (Olive baboon). Abhydrolase domain containing 10 Papio anubis
rhiro-a0a2k6nj56 Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana). Abhydrolase domain containing 10 Rhinopithecus roxellana
chlsb-a0a0d9r2l6 Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus). Abhydrolase domain containing 10 Chlorocebus sabaeus
colap-a0a2k5k737 Colobus angolensis palliatus (Peters' Angolan colobus). Abhydrolase domain containing 10 Colobus angolensis palliatus
rhibe-a0a2k6mu25 Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti). Abhydrolase domain containing 10 Rhinopithecus bieti
aotna-a0a2k5ei86 Aotus nancymaae (Ma's night monkey). Abhydrolase domain containing 10 Aotus nancymaae
saibb-a0a2k6s303 Saimiri boliviensis boliviensis (Bolivian squirrel monkey). Abhydrolase domain containing 10 Saimiri boliviensis boliviensis
calja-u3cmb7 Callithrix jacchus (White-tufted-ear marmoset). Alpha\/beta hydrolase domain-containing protein 10, mitochondrial isoform 1 Callithrix jacchus
cebca-a0a2k5rq06 Cebus capucinus imitator. Abhydrolase domain containing 10 Cebus capucinus imitator
proco-a0a2k6etc6 Propithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi coquereli). Abhydrolase domain containing 10 Propithecus coquereli
tarsy-a0a1u7uhk2 Tarsius syrichta (Philippine tarsier). mycophenolic acid acyl-glucuronide esterase, mitochondrial isoform X1 Tarsius syrichta
icttr-i3lyc1 Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus tridecemlineatus). Abhydrolase domain containing 10 Ictidomys tridecemlineatus
rabit-g1skt3 Oryctolagus cuniculus (Rabbit). Abhydrolase domain containing 10 Oryctolagus cuniculus
phycd-a0a2y9sby1 Physeter catodon (Sperm whale) (Physeter macrocephalus)\; Eschrichtius robustus (California gray whale) (Eschrichtius gibbosus). mycophenolic acid acyl-glucuronide esterase, mitochondrial Physeter catodon
lipve-a0a340y7m5 Lipotes vexillifer (Yangtze river dolphin). mycophenolic acid acyl-glucuronide esterase, mitochondrial Lipotes vexillifer
turtr-a0a2u4abh8 Tursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus). mycophenolic acid acyl-glucuronide esterase, mitochondrial isoform X1 Tursiops truncatus
9ceta-a0a341amk9 Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise). mycophenolic acid acyl-glucuronide esterase, mitochondrial isoform X1 Neophocaena asiaeorientalis asiaeorientalis
delle-a0a2y9qi19 Delphinapterus leucas (Beluga whale). mycophenolic acid acyl-glucuronide esterase, mitochondrial Delphinapterus leucas
trima-a0a2y9qmf8 Trichechus manatus latirostris (Florida manatee). mycophenolic acid acyl-glucuronide esterase, mitochondrial isoform X1 Trichechus manatus latirostris
sheep-w5qd48 Ovis aries (Sheep). Abhydrolase domain containing 10 Ovis aries
ursma-a0a384dcs9 Ursus maritimus (Polar bear) (Thalarctos maritimus). mycophenolic acid acyl-glucuronide esterase, mitochondrial Ursus maritimus
pig-a0a287al53 Sus scrofa (Pig). Abhydrolase domain containing 10 Sus scrofa
balas-a0a384a444 Balaenoptera acutorostrata scammoni (North Pacific minke whale) (Balaenoptera davidsoni). mycophenolic acid acyl-glucuronide esterase, mitochondrial isoform X1 Balaenoptera acutorostrata scammoni
odoro-a0a2u3vb18 Odobenus rosmarus divergens (Pacific walrus). mycophenolic acid acyl-glucuronide esterase, mitochondrial Odobenus rosmarus divergens
lepwe-a0a2u3yb99 Leptonychotes weddellii (Weddell seal). mycophenolic acid acyl-glucuronide esterase, mitochondrial Leptonychotes weddellii
neosc-a0a2y9hes2 Neomonachus schauinslandi (Hawaiian monk seal) (Monachus schauinslandi). mycophenolic acid acyl-glucuronide esterase, mitochondrial Neomonachus schauinslandi
cascn-a0a250xy53 Castor canadensis (American beaver). Mycophenolic acid acyl-glucuronide esterase, mitochondrial Castor canadensis
horse-f6zna7 Equus caballus (Horse). Abhydrolase domain containing 10 Equus caballus
gulgu-a0a3p4lda9 Gulo gulo (Wolverine) (Gluton). Uncharacterized protein Gulo gulo
ailme-g1mik5 Ailuropoda melanoleuca (Giant panda). Abhydrolase domain containing 10 Ailuropoda melanoleuca
canlf-j9p8h1 Canis lupus familiaris (Dog) (Canis familiaris). Abhydrolase domain containing 10 Canis lupus familiaris
neovi-u6cv13 Neovison vison (American mink) (Mustela vison). Abhydrolase domain-containing protein 10, mitochondrial Neovison vison
enhlu-a0a2y9jyx5 Enhydra lutris kenyoni (northern sea otter). mycophenolic acid acyl-glucuronide esterase, mitochondrial Enhydra lutris kenyoni
hetga-a0a0p6jw61 Heterocephalus glaber (Naked mole rat). Abhydrolase domain-containing protein 10, mitochondrial Heterocephalus glaber
erieu-a0a1s2zah9 Erinaceus europaeus (Western European hedgehog). mycophenolic acid acyl-glucuronide esterase, mitochondrial Erinaceus europaeus
felca-m3x2j4 Felis catus (Cat) (Felis silvestris catus). Uncharacterized protein Felis catus
camfr-s9w5f6 Camelus ferus (Wild bactrian camel) (Camelus bactrianus ferus). Mycophenolic acid acyl-glucuronide esterase, mitochondrial Camelus ferus
pteal-l5l537 Pteropus alecto (Black flying fox). Abhydrolase domain-containing protein 10, mitochondrial Pteropus alecto
dipor-a0a1s3g5m2 Dipodomys ordii (Ord's kangaroo rat). mycophenolic acid acyl-glucuronide esterase, mitochondrial Dipodomys ordii
myolu-g1nzg3 Myotis lucifugus (Little brown bat). Abhydrolase domain containing 10 Myotis lucifugus
otoga-h0wzg1 Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby). Abhydrolase domain containing 10 Otolemur garnettii
mesau-a0a1u7qam6 Mesocricetus auratus (Golden hamster). mycophenolic acid acyl-glucuronide esterase, mitochondrial Mesocricetus auratus
cavpo-h0v5z0 Cavia porcellus (Guinea pig). Abhydrolase domain containing 10 Cavia porcellus
crigr-g3h083 Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus). Abhydrolase domain-containing protein 10, mitochondrial Cricetulus griseus
cereh-a0a212c355 Cervus elaphus hippelaphus (European red deer). ABHD10 Cervus elaphus hippelaphus
mondo-f7fg39 Monodelphis domestica (Gray short-tailed opossum). Abhydrolase domain containing 10 Monodelphis domestica
sarha-g3wtu4 Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius). Abhydrolase domain containing 10 Sarcophilus harrisii
myods-l5lwe4 Myotis davidii (David's myotis). Abhydrolase domain-containing protein 10, mitochondrial Myotis davidii
patfa-a0a1v4jb02 Patagioenas fasciata monilis. Mycophenolic acid acyl-glucuronide esterase, mitochondrial Patagioenas fasciata monilis
allsi-a0a3q0hdl7 Alligator sinensis (Chinese alligator). mycophenolic acid acyl-glucuronide esterase, mitochondrial Alligator sinensis
colli-a0a2i0mlj2 Columba livia (Rock dove). Abhydrolase domain containing 10 Columba livia
allmi-a0a151mdb6 Alligator mississippiensis (American alligator). Abhydrolase domain containing 10 Alligator mississippiensis
pelsi-k7gh41 Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis). Abhydrolase domain containing 10 Pelodiscus sinensis
pelcr-a0a091tm85 Pelecanus crispus (Dalmatian pelican). Uncharacterized protein Pelecanus crispus
anapl-u3i5h5 Anas platyrhynchos (Mallard) (Anas boschas). Abhydrolase domain containing 10 Anas platyrhynchos
strca-a0a093jrz9 Struthio camelus australis. Uncharacterized protein Struthio camelus australis
nipni-a0a091v6s5 Nipponia nippon (Crested ibis) (Ibis nippon)\; Phalacrocorax carbo (Great cormorant) (Pelecanus carbo)\; Cathartes aura (Turkey vulture) (Vultur aura)\; Gavia stellata (Red-throated diver) (Red-throated loon)\; Egretta garzetta (Little egret)\; Eurypyga helias (Sunbittern). Uncharacterized protein Nipponia nippon
taegu-h0ztq1 Taeniopygia guttata (Zebra finch) (Poephila guttata). Abhydrolase domain containing 10 Taeniopygia guttata
chavo-a0a0a0aqh2 Charadrius vociferus (Killdeer) (Aegialitis vocifera)\; Manacus vitellinus (golden-collared manakin)\; Haliaeetus albicilla (White-tailed sea-eagle)\; Fulmarus glacialis (Northern fulmar)\; Calypte anna (Anna's hummingbird) (Archilochus anna)\; Tinamus guttatus (White-throated tinamou)\; Cariama cristata (Red-legged seriema)\; Tyto alba (Barn owl)\; Limosa lapponica baueri. Uncharacterized protein Charadrius vociferus
hirru-a0a3m0kfp7 Hirundo rustica rustica. Uncharacterized protein Hirundo rustica rustica
chick-a0a1d5pj73 Gallus gallus (Chicken). Abhydrolase domain containing 10 Gallus gallus
aptfo-a0a087qt38 Aptenodytes forsteri (Emperor penguin). Uncharacterized protein Aptenodytes forsteri
pygad-a0a093nqa9 Pygoscelis adeliae (Adelie penguin). Uncharacterized protein Pygoscelis adeliae
nesno-a0a091rwi3 Nestor notabilis (Kea)\; Mesitornis unicolor (brown roatelo)\; Podiceps cristatus (Great crested grebe)\; Cuculus canorus (common cuckoo)\; Phoenicopterus ruber ruber\; Opisthocomus hoazin (Hoatzin) (Phasianus hoazin)\; Tauraco erythrolophus (Red-crested turaco)\; Merops nubicus (Northern carmine bee-eater)\; Dryobates pubescens (Downy woodpecker) (Picoides pubescens). Uncharacterized protein Nestor notabilis
anoca-g1kqp8 Anolis carolinensis (Green anole) (American chameleon). Abhydrolase domain containing 10 Anolis carolinensis
corbr-a0a091f6y9 Corvus brachyrhynchos (American crow). Uncharacterized protein Corvus brachyrhynchos
chlgu-a0a3l8sk00 Chloebia gouldiae (Gouldian finch) (Erythrura gouldiae). Uncharacterized protein Chloebia gouldiae
xentr-f7eue5 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis). Abhydrolase domain-containing 10 Xenopus tropicalis
9pase-a0a218ujv2 Lonchura striata domestica (Bengalese finch). Mycophenolic acid acyl-glucuronide esterase, mitochondrial Lonchura striata domestica
amaae-a0a0q3pme8 Amazona aestiva (Blue-fronted Amazon parrot). Mycophenolic acid acyl-glucuronide esterase Amazona aestiva
fical-u3jv12 Ficedula albicollis (Collared flycatcher) (Muscicapa albicollis). Abhydrolase domain containing 10 Ficedula albicollis
latch-h3av70 Latimeria chalumnae (West Indian ocean coelacanth). Uncharacterized protein Latimeria chalumnae
oreni-i3k9m0 Oreochromis niloticus (Nile tilapia) (Tilapia nilotica). Uncharacterized protein Oreochromis niloticus
oryla-a0a3p9kz03 Oryzias latipes (Japanese rice fish) (Japanese killifish). Uncharacterized protein Oryzias latipes
oryme-a0a3b3bnt1 Oryzias melastigma (Marine medaka).Abhydrolase domain containing 10 Oryzias melastigma
9tele-a0a0p7xhe1 Scleropages formosus (Asian bonytongue). Mycophenolic acid acyl-glucuronide esterase, mitochondrial-like Scleropages formosus
ophha-v8p430 Ophiophagus hannah (King cobra) (Naja hannah)\; Micrurus lemniscatus lemniscatus\; Micrurus corallinus (Brazilian coral snake). Abhydrolase domain-containing protein 10, mitochondrial Ophiophagus hannah
cynse-a0a3p8wch2 Cynoglossus semilaevis (Tongue sole). . Abhydrolase domain-containing protein 10, mitochondrial Cynoglossus semilaevis
xenla-a0a1l8hei7 Xenopus laevis (African clawed frog). Uncharacterized protein Xenopus laevis
9tele-a0a3b4z349 Stegastes partitus (bicolor damselfish). Uncharacterized protein Stegastes partitus
pygna-a0a3b4ddu9 Pygocentrus nattereri (Red-bellied piranha). Abhydrolase domain containing 10a Pygocentrus nattereri
xipma-m4a5i1 Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus). Abhydrolase domain containing 10 Xiphophorus maculatus
poefo-a0a087xju7 Poecilia formosa (Amazon molly) (Limia formosa)\; P. reticulata (Guppy) (Acanthophacelus reticulatus)\; P. mexicana\; P. latipinna (sailfin molly). Abhydrolase domain containing 10 Poecilia formosa
notfu-a0a1a7zh85 Nothobranchius furzeri (Turquoise killifish)\; N. kuhntae (Beira killifish)\; N. pienaari\; N. rachovii (bluefin notho)\; N. kadlec\; N korthausa. Abhydrolase domain containing 10b Nothobranchius furzeri
9cich-a0a3b4f2h8 Pundamilia nyererei. Abhydrolase domain containing 10 Pundamilia nyererei
serll-a0a3b4wpd5 Seriola lalandi dorsalis. Abhydrolase domain containing 10 Seriola lalandi dorsalis
9cich-a0a3p9d5c0 Maylandia zebra (zebra mbuna). Abhydrolase domain containing 10 Maylandia zebra
9tele-a0a1a7wf21 Iconisemion striatum. Abhydrolase domain containing 10b Iconisemion striatum
9gobi-a0a3b4biy6 Periophthalmus magnuspinnatus. Abhydrolase domain containing 10 Periophthalmus magnuspinnatus
pygna-a0a3b4d7m6 Pygocentrus nattereri (Red-bellied piranha). Abhydrolase domain containing 10b Pygocentrus nattereri
takru-a0a3b5k333 Takifugu rubripes (Japanese pufferfish) (Fugu rubripes). Abhydrolase domain containing 10 Takifugu rubripes
oncmy-a0a060xym5 Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri). Uncharacterized protein Oncorhynchus mykiss
amppe-a0a3p8tr77 Amphiprion percula (Orange clownfish) (Lutjanus percula).Abhydrolase domain containing 10 Amphiprion percula
poere-a0a3p9q5a0 Poecilia reticulata (Guppy) (Acanthophacelus reticulatus).Abhydrolase domain containing 10 Poecilia reticulata
9tele-a0a3b3sv81 Paramormyrops kingsleyae. Abhydrolase domain containing 10 Paramormyrops kingsleyae
astca-a0a3p8r9z3 Astatotilapia calliptera (Eastern happy) (Chromis callipterus).Abhydrolase domain containing 10 Astatotilapia calliptera
astmx-a0a3b1it79 Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus).Abhydrolase domain containing 10 Astyanax mexicanus
oncmy-a0a060xqc7 Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri). Uncharacterized protein Oncorhynchus mykiss
gasac-g3nf40 Gasterosteus aculeatus (Three-spined stickleback). Abhydrolase domain-containing protein 10 Gasterosteus aculeatus
anaga-a0a3n0ye42 Anabarilius grahami (Kanglang fish) (Barilius grahami). Mycophenolic acid acyl-glucuronide esterase, mitochondrial Anabarilius grahami
dicla-e6zir2 Dicentrarchus labrax (European seabass) (Morone labrax). Abhydrolase domain-containing protein 10, mitochondrial Dicentrarchus labrax
gamaf-a0a315v3l0 Gambusia affinis (Western mosquitofish) (Heterandria affinis). Uncharacterized protein Gambusia affinis
salsa-a0a1s3nid3 Salmo salar (Atlantic salmon). mycophenolic acid acyl-glucuronide esterase, mitochondrial Salmo salar
funhe-a0a146zwf5 Fundulus heteroclitus (Killifish) (Mummichog). Mycophenolic acid acyl-glucuronide esterase, mitochondrial Fundulus heteroclitus
serdu-a0a3b4una4 Seriola dumerili (Mediterranean greater amberjack) (Caranx dumerili).Abhydrolase domain containing 10 Seriola dumerili
esolu-a0a3p8z2a3 Esox lucius (Northern pike). Abhydrolase domain containing 10a Esox lucius
salsa-b5x2x7 Salmo salar (Atlantic salmon). mycophenolic acid acyl-glucuronide esterase, mitochondrial-like Salmo salar
calmi-v9ki07 Callorhinchus milii (Ghost shark). Abhydrolase domain-containing 10 Callorhinchus milii
esolu-a0a3p9a4q6 Esox lucius (Northern pike).Abhydrolase domain containing 10 Esox lucius
melga-g1nnl1 Meleagris gallopavo (Wild turkey). Abhydrolase domain containing 10 Meleagris gallopavo
oncmy-a0a060xjn9 Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri). Uncharacterized protein Oncorhynchus mykiss
oncmy-a0a060wwr6 Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri). Uncharacterized protein Oncorhynchus mykiss
ictpu-w5u6h4 Ictalurus punctatus (Channel catfish) (Silurus punctatus). Mycophenolic acid acyl-glucuronide esterase, mitochondrial Ictalurus punctatus
9tele-a0a2i4aqg1 Austrofundulus limnaeus. mycophenolic acid acyl-glucuronide esterase, mitochondrial Austrofundulus limnaeus
salsa-a0a1s3l1l0 Salmo salar (Atlantic salmon). mycophenolic acid acyl-glucuronide esterase, mitochondrial-like Salmo salar
ictpu-a0a2d0qam4 Ictalurus punctatus (Channel catfish) (Silurus punctatus). mycophenolic acid acyl-glucuronide esterase, mitochondrial-like Ictalurus punctatus
9tele-a0a0s7hi29 Poeciliopsis prolifica (blackstripe livebearer). ABHDA Poeciliopsis prolifica
anaga-a0a3n0xym7 Anabarilius grahami (Kanglang fish) (Barilius grahami). Acyl-coenzyme A thioesterase 9, mitochondrial Anabarilius grahami
latch-h3bhd6 Latimeria chalumnae (West Indian ocean coelacanth). Uncharacterized protein Latimeria chalumnae
scomx-a0a2u9cx05 Scophthalmus maximus (Turbot) (Psetta maxima). Abhydrolase domain-containing protein 10 mitochondrial isoform 5 Scophthalmus maximus
lepoc-w5mac0 Lepisosteus oculatus (Spotted gar).Abhydrolase domain containing 10 Lepisosteus oculatus
chemy-m7c0i8 Chelonia mydas (Green sea-turtle) (Chelonia agassizi). Abhydrolase domain-containing protein 10 Chelonia mydas
calmi-k4fsh3 Callorhinchus milii (Ghost shark). Abhydrolase domain-containing protein 10, mitochondrial Callorhinchus milii
colvi-a0a226nwe6 Colinus virginianus (Northern bobwhite) (Tetrao virginianus). Uncharacterized protein Colinus virginianus
calsu-a0a226nc51 Callipepla squamata (Scaled quail). Uncharacterized protein Callipepla squamata
esolu-a0a3p9a519 Esox lucius (Northern pike).Abhydrolase domain containing 10 Esox lucius
brafl-c3zj72 Branchiostoma floridae (Florida lancelet) (Amphioxus). Uncharacterized protein Branchiostoma floridae
9cnid-a0a3m6tea2 Pocillopora damicornis. Uncharacterized protein Pocillopora damicornis
nemve-a7rvd5 Nematostella vectensis (Starlet sea anemone). Predicted protein Nematostella vectensis
stypi-a0a2b4ssu6 Stylophora pistillata (Smooth cauliflower coral). Predicted protein Stylophora pistillata
chemy-m7bsp5 Chelonia mydas (Green sea-turtle) (Chelonia agassizi). Abhydrolase domain-containing protein 10 Chelonia mydas
linun-a0a1s3hjn7 Lingula unguis. mycophenolic acid acyl-glucuronide esterase, mitochondrial-like Lingula unguis
linun-a0a1s3hlk0 Lingula unguis. mycophenolic acid acyl-glucuronide esterase, mitochondrial-like Lingula unguis
strpu-w4ymz7 Strongylocentrotus purpuratus (Purple sea urchin). Uncharacterized protein Strongylocentrotus purpuratus

Gene_locus_frgt Name Species
muspf-m3xmu1 Mustela putorius furo (European domestic ferret) (Mustela furo). Abhydrolase domain containing 10 Mustela putorius furo
loxaf-g3t6f8 Loxodonta africana (African elephant). Abhydrolase domain containing 10 Loxodonta africana
tupch-l9kbh3 Tupaia chinensis (Chinese tree shrew). Abhydrolase domain-containing protein 10, mitochondrial Tupaia chinensis
myobr-s7pub8 Myotis brandtii (Brandt's bat). Abhydrolase domain-containing protein 10, mitochondrial Myotis brandtii
fukda-a0a091dki3 Fukomys damarensis (Damaraland mole rat) (Cryptomys damarensis). Abhydrolase domain-containing protein 10, mitochondrial Fukomys damarensis
astmx-a0a3b1jri1 Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus). Abhydrolase domain containing 10a Astyanax mexicanus
neole-a0a1a6h6y0 Neotoma lepida (Desert woodrat). Uncharacterized protein Neotoma lepida
ornan-f6qiu7 Ornithorhynchus anatinus (Duckbill platypus). Uncharacterized protein Ornithorhynchus anatinus
salsa-a0a1s3qwe4 Salmo salar (Atlantic salmon). mycophenolic acid acyl-glucuronide esterase, mitochondrial-like Salmo salar
litct-a0a2g9s2w3 Lithobates catesbeiana (American bullfrog) (Rana catesbeiana). Uncharacterized protein Lithobates catesbeiana
tupch-l9l8w9 Tupaia chinensis (Chinese tree shrew). Abhydrolase domain-containing protein 10, mitochondrial Tupaia chinensis

Substrate Chemical Nomenclature Proteins
Depalmitoylation-probe-5 4-[4-[6'-[[(2R)-3-hexadecanoylsulfanyl-1-(methylamino)-1-oxopropan-2-yl]-methylcarbamoyl]oxy-3-oxospiro[2-benzofuran-1,9'-xanthene]-3'-yl]piperazin-1-yl]-4-oxobutanoic acid mouse-abhda    human-ABHD10    human-LYPLA1    human-LYPLA2
Depalmitoylation-probe-2 S-[(2R)-2-[[6'-(dimethylamino)-3-oxospiro[2-benzofuran-1,9'-xanthene]-3'-yl]oxycarbonyl-methylamino]-3-(methylamino)-3-oxopropyl] octanethioate human-LYPLA1    human-LYPLA2    human-ABHD17A    human-ABHD10    mouse-abhda
mitoDPP-2 [3-[4-[6'-[methyl-[(2R)-1-(methylamino)-3-octanoylsulfanyl-1-oxopropan-2-yl]carbamoyl]oxy-3-oxospiro[2-benzofuran-1,9'-xanthene]-3'-yl]piperazin-1-yl]-3-oxopropyl]-triphenylphosphanium mouse-abhda    human-ABHD10
Probenecid-glucuronide (2S,3S,4S,5R,6S)-6-[4-(dipropylsulfamoyl)benzoyl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid human-ABHD10
Mycophenolic-acid-acyl-glucuronide (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[(E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoyl]oxyoxane-2-carboxylic acid human-ABHD10

Inhibitor Chemical Nomenclature Proteins
mitoFP 4-[fluoro(octoxy)phosphoryl]butyl-triphenylphosphanium\;fluoride mouse-abhda    human-ABHD10    human-LYPLA1
ABL-303 dipropan-2-yl 3-ethyl-3-(4-methylphenyl)-4-oxodiazetidine-1,2-dicarboxylate human-ABHD10
Rocaglate-Derived-beta-Lactone-5 (1S,9R,10S,11R,14R)-1-hydroxy-3,5-dimethoxy-9-(4-methoxyphenyl)-10-phenyl-8,13-dioxatetracyclo[7.5.0.02,7.011,14]tetradeca-2(7),3,5-trien-12-one human-ABHD10    human-SCPEP1    human-ACOT1    human-ACOT2    human-CTSA
2-methyl-pentane-2,4-diol (4S)-2-methylpentane-2,4-diol human-MGLL    manes-hnl    mouse-abhda    bactn-BT4077    orysj-q10j20
PMSF Phenylmethylsulfonyl fluoride theet-q3ch51    emeni-q5avy9    human-ABHD10    human-PREPL    myctu-Rv1430    psefl-cxest    9bact-E40    thefu-q6a0i4    ecoli-Aes    orysj-Q10QA5    bac25-mglp    9bact-Q0GMU2    bacsu-FENB    psepu-clcd1    thema-TM0077    bacsu-RsbQ    ecoli-bioh    drome-CG9542    human-FAP    tubmm-TmEst2    human-NOTUM    cutac-e6dae5    9gamm-urc15994    9baci-EstD9    geost-est30    pholl-AntI

References (7)

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Author(s) : Cao Y , Qiu T , Kathayat RS , Azizi SA , Thorne AK , Ahn D , Fukata Y , Fukata M , Rice PA , Dickinson BC
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Abstract :
PubMedSearch : Cao_2019_Nat.Chem.Biol_15_1232
PubMedID: 31740833
Gene_locus related to this paper: human-ABHD10 , mouse-abhda

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Author(s) : Fukami T
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Abstract :
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Gene_locus related to this paper: human-ABHD10

Title : An Orphan Esterase ABHD10 Modulates Probenecid Acyl Glucuronidation in Human Liver - Ito_2014_Drug.Metab.Dispos_42_2109
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Abstract :
PubMedSearch : Ito_2014_Drug.Metab.Dispos_42_2109
PubMedID: 25217485
Gene_locus related to this paper: human-ABHD10 , mouse-abhda

Title : Remodeling natural products: chemistry and serine hydrolase activity of a rocaglate-derived beta-lactone - Lajkiewicz_2014_J.Am.Chem.Soc_136_2659
Author(s) : Lajkiewicz NJ , Cognetta AB, 3rd , Niphakis MJ , Cravatt BF , Porco JA, Jr.
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PubMedSearch : Lajkiewicz_2014_J.Am.Chem.Soc_136_2659
PubMedID: 24447064
Gene_locus related to this paper: human-ABHD10 , human-ACOT1 , human-ACOT2 , human-CTSA , human-SCPEP1 , mouse-abhda

Title : Human alpha\/beta hydrolase domain containing 10 (ABHD10) is responsible enzyme for deglucuronidation of mycophenolic acid acyl-glucuronide in liver - Iwamura_2012_J.Biol.Chem_287_9240
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Ref : Journal of Biological Chemistry , 287 :9240 , 2012
Abstract :
PubMedSearch : Iwamura_2012_J.Biol.Chem_287_9240
PubMedID: 22294686
Gene_locus related to this paper: human-ABHD10 , mouse-abhda

Title : Competitive activity-based protein profiling identifies aza-beta-lactams as a versatile chemotype for serine hydrolase inhibition - Zuhl_2012_J.Am.Chem.Soc_134_5068
Author(s) : Zuhl AM , Mohr JT , Bachovchin DA , Niessen S , Hsu KL , Berlin JM , Dochnahl M , Lopez-Alberca MP , Fu GC , Cravatt BF
Ref : J Am Chem Soc , 134 :5068 , 2012
Abstract :
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Gene_locus related to this paper: human-ABHD10

Title : The emerging role of human esterases - Fukami_2012_Drug.Metab.Pharmacokinet_27_466
Author(s) : Fukami T , Yokoi T
Ref : Drug Metab Pharmacokinet , 27 :466 , 2012
Abstract :
PubMedSearch : Fukami_2012_Drug.Metab.Pharmacokinet_27_466
PubMedID: 22813719
Gene_locus related to this paper: human-ABHD10