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Author Report for: Sharma A

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    Title: Design, Synthesis, and Pharmacological Evaluation of Embelin-Aryl/alkyl Amine Hybrids as Orally Bioavailable Blood-Brain Barrier Permeable Multitargeted Agents with Therapeutic Potential in Alzheimer's Disease: Discovery of SB-1448
    Nuthakki VK, Choudhary S, Reddy CN, Bhatt S, Jamwal A, Jotshi A, Raghuvanshi R, Sharma A, Thakur S and Bharate SB <4 more author(s)>
    Ref: ACS Chem Neurosci, :, 2023 : PubMed


    Title: Acridine: A Scaffold for the development of drugs for Alzheimer's disease
    Sharma A, Piplani P
    Ref: Curr Top Med Chem, :, 2023 : PubMed


    Title: Synthesis and Biological Evaluation of Coumarin Triazoles as Dual Inhibitors of Cholinesterases and beta-Secretase
    Sharma A, Bharate SB
    Ref: ACS Omega, 8:11161, 2023 : PubMed


    Title: Discovery of blood-brain barrier permeable and orally bioavailable caffeine-based amide derivatives as acetylcholinesterase inhibitors
    Sharma M, Sharma A, Thakur S, Nuthakki VK, Jamwal A, Nandi U, Jadhav HR, Bharate SB
    Ref: Bioorg Chem, 139:106719, 2023 : PubMed


    Title: Nano polystyrene induced changes in anxiety and learning behaviour are mediated through oxidative stress and gene disturbance in mouse brain regions
    Sharma A, Kaur M, Sharma K, Bunkar SK, John P, Bhatnagar P
    Ref: Neurotoxicology, 99:139, 2023 : PubMed


    Title: Pathogenesis of Alzheimer's Disease and Diversity of 1,2,3-Triazole Scaffold in Drug Development: Design Strategies, Structural Insights, and Therapeutic Potential
    Singh A, Singh K, Kaur J, Kaur R, Sharma A, Kaur U, Chadha R, Bedi PMS
    Ref: ACS Chem Neurosci, :, 2023 : PubMed


    Title: Unravelling consensus genomic regions associated with quality traits in wheat using meta-analysis of quantitative trait loci
    Gudi S, Saini DK, Singh G, Halladakeri P, Kumar P, Shamshad M, Tanin MJ, Singh S, Sharma A
    Ref: Planta, 255:115, 2022 : PubMed


    Title: Mechano-chemical and biological energetics of immobilized enzymes onto functionalized polymers and their applications
    Sharma T, Xia C, Sharma A, Raizada P, Singh P, Sharma S, Sharma P, Kumar S, Lam S, Nadda AK
    Ref: Bioengineered, 13:10518, 2022 : PubMed


    Title: A Coumarin-donepezil Hybrid as a Blood-brain Barrier Permeable Dual Cholinesterase Inhibitor: Isolation, Synthetic Modifications and Biological Evaluation of Natural Coumarins
    Sharma A, Nuthakki VK, Gairola S, Singh B, Bharate SB
    Ref: ChemMedChem, :, 2022 : PubMed


    Title: Design, synthesis, and structure-activity relationship of caffeine-based triazoles as dual AChE and BACE-1 inhibitors
    Sharma M, Sharma A, Nuthakki VK, Bhatt S, Nandi U, Bharate SB
    Ref: Drug Dev Res, :, 2022 : PubMed


    Title: Donepezil-Inspired Multitargeting Indanone Derivatives as Effective Anti-Alzheimer's Agents
    Singh JV, Thakur S, Kumar N, Singh H, Mithu VS, Bhagat K, Gulati HK, Sharma A, Sharma S, Bedi PMS
    Ref: ACS Chem Neurosci, :, 2022 : PubMed


    Title: Synthesis and evaluation of small organic molecule as reactivator of organophosphorus inhibited acetylcholinesterase
    Thakur A, Patwa J, Pant S, Jeet Singh Flora S, Sharma A
    Ref: Drug & Chemical Toxicology, :1, 2022 : PubMed


    Title: Clinical Evidence of Evogliptin plus Metformin in Management of Type 2 Diabetes mellitus
    Bajaj S, Aiwale A, Trailokya A, Sharma A
    Ref: J Assoc Physicians India, 69:25, 2021 : PubMed


    Title: Purification of high molecular weight thermotolerant esterase from Serratia sp. and its characterization
    Bhardwaj KK, Kishen S, Mehta A, Sharma A, Gupta R
    Ref: 3 Biotech, 11:308, 2021 : PubMed


    Title: Organic-Molecule-Based Fluorescent Chemosensor for Nerve Agents and Organophosphorus Pesticides
    Gori M, Thakur A, Sharma A, Flora SJS
    Ref: Top Curr Chem (Cham), 379:33, 2021 : PubMed


    Title: Oxidative damage in the liver and brain of the rats exposed to frequency-dependent radiofrequency electromagnetic exposure: Biochemical and histopathological evidence
    Sharma A, Shrivastava S, Shukla S
    Ref: Free Radical Research, :1, 2021 : PubMed


    Title: Binary Prodrug of Dichloroacetic Acid and Doxorubicin with Enhanced Anticancer Activity
    Sharma A, Chun J, Ji MS, Lee S, Kang C, Kim JS
    Ref: ACS Appl Bio Mater, 4:2026, 2021 : PubMed


    Title: Therapeutic effects of biochanin A, phloretin, and epigallocatechin-3-gallate in reducing oxidative stress in arsenic-intoxicated mice
    Singh G, Thaker R, Sharma A, Parmar D
    Ref: Environ Sci Pollut Res Int, :, 2021 : PubMed


    Title: Synthesis, Molecular Docking, BSA, and in-vitro reactivation study of imidazopyridine oxime against paraoxon inhibited acetylcholinesterase
    Thakur A, Patwa J, Sharma A, Flora SJ
    Ref: Med Chem, :, 2021 : PubMed


    Title: Exploring the Multifaceted Therapeutic Potential of Withaferin A and Its Derivatives
    Behl T, Sharma A, Sharma L, Sehgal A, Zengin G, Brata R, Fratila O, Bungau S
    Ref: Biomedicines, 8:, 2020 : PubMed


    Title: Biomarkers for the toxicity of sublethal concentrations of triclosan to the early life stages of carps
    Dar OI, Sharma S, Singh K, Sharma A, Bhardwaj R, Kaur A
    Ref: Sci Rep, 10:17322, 2020 : PubMed


    Title: Monoisoamyl DMSA reduced copper-induced neurotoxicity by lowering 8-OHdG level, amyloid beta and Tau protein expressions in Sprague-Dawley rats
    Patwa J, Thakur A, Sharma A, Flora SJS
    Ref: Metallomics, 12:1428, 2020 : PubMed


    Title: Efficacy of Bacopa Monnieri (Brahmi) and Donepezil in Alzheimer's Disease and Mild Cognitive Impairment: A Randomized Double-Blind Parallel Phase 2b Study
    Prabhakar S, Vishnu VY, Modi M, Mohanty M, Sharma A, Medhi B, Mittal BR, Khandelwal N, Goyal MK and Avasthi A <3 more author(s)>
    Ref: Ann Indian Acad Neurol, 23:767, 2020 : PubMed


    Title: Necrosis and necroptosis in germ cell depletion from mammalian ovary
    Chaudhary GR, Yadav PK, Yadav AK, Tiwari M, Gupta A, Sharma A, Sahu K, Pandey AN, Pandey AK, Chaube SK
    Ref: Journal of Cellular Physiology, 234:8019, 2019 : PubMed


    Title: Synthesis and biological evaluation of indoloquinoline alkaloid cryptolepine and its bromo-derivative as dual cholinesterase inhibitors
    Nuthakki VK, Mudududdla R, Sharma A, Kumar A, Bharate SB
    Ref: Bioorg Chem, 90:103062, 2019 : PubMed


    Title: Identification of embelin, a 3-undecyl-1,4-benzoquinone from Embelia ribes as a multitargeted anti-Alzheimer agent
    Nuthakki VK, Sharma A, Kumar A, Bharate SB
    Ref: Drug Dev Res, 80:655, 2019 : PubMed


    Title: Comprehensive genomic and transcriptomic analysis of polycyclic aromatic hydrocarbon degradation by a mycoremediation fungus, Dentipellis sp. KUC8613
    Park H, Min B, Jang Y, Kim J, Lipzen A, Sharma A, Andreopoulos B, Johnson J, Riley R and Choi IG <5 more author(s)>
    Ref: Applied Microbiology & Biotechnology, 103:8145, 2019 : PubMed


    Title: Mobile phone induced cognitive and neurochemical consequences
    Sharma A, Sharma S, Shrivastava S, Singhal PK, Shukla S
    Ref: Journal of Chemical Neuroanatomy, :101684, 2019 : PubMed


    Title: Characterization of ML0314c of Mycobacterium leprae and deciphering its role in the immune response in leprosy patients
    Kaur G, Sharma A, Narang T, Dogra S, Kaur J
    Ref: Gene, 643:26, 2018 : PubMed


    Title: Design, synthesis and pharmacological evaluation of some novel indanone derivatives as acetylcholinesterase inhibitors for the management of cognitive dysfunction
    Piplani P, Jain A, Devi D, Anjali, Sharma A, Silakari P
    Ref: Bioorganic & Medicinal Chemistry, 26:215, 2018 : PubMed


    Title: Molecular characterization and bioinformatics studies of a lipase from Bacillus thermoamylovorans BHK67
    Sharma A, Meena KR, Kanwar SS
    Ref: Int J Biol Macromol, 107:2131, 2018 : PubMed


    Title: Jasmonic Acid Seed Treatment Stimulates Insecticide Detoxification in Brassica juncea L
    Sharma A, Kumar V, Yuan H, Kanwar MK, Bhardwaj R, Thukral AK, Zheng B
    Ref: Front Plant Sci, 9:1609, 2018 : PubMed


    Title: Advances in Multi-Functional Ligands and the Need for Metal-Related Pharmacology for the Management of Alzheimer Disease
    Sharma A, Pachauri V, Flora SJS
    Ref: Front Pharmacol, 9:1247, 2018 : PubMed


    Title: Arsenic-induced oxidative stress, cholinesterase activity in the brain of Swiss albino mice, and its amelioration by antioxidants Vitamin E and Coenzyme Q10
    Sharma A, Kshetrimayum C, Sadhu HG, Kumar S
    Ref: Environ Sci Pollut Res Int, 25:23946, 2018 : PubMed


    Title: mesT, a unique epoxide hydrolase, is essential for optimal growth of Mycobacterium tuberculosis in the presence of styrene oxide
    Chownk M, Sharma A, Singh K, Kaur J
    Ref: Future Microbiol, 12:527, 2017 : PubMed


    Title: Demodex canis regulates cholinergic system mediated immunosuppressive pathways in canine demodicosis
    Kumari P, Nigam R, Singh A, Nakade UP, Sharma A, Garg SK, Singh SK
    Ref: Parasitology, :1, 2017 : PubMed


    Title: 24-epibrassinolide stimulates imidacloprid detoxification by modulating the gene expression of Brassica juncea L
    Sharma A, Thakur S, Kumar V, Kesavan AK, Thukral AK, Bhardwaj R
    Ref: BMC Plant Biol, 17:56, 2017 : PubMed


    Title: The prostate metastasis suppressor gene NDRG1 differentially regulates cell motility and invasion
    Sharma A, Mendonca J, Ying J, Kim HS, Verdone JE, Zarif JC, Carducci M, Hammers H, Pienta KJ, Kachhap S
    Ref: Mol Oncol, 11:655, 2017 : PubMed


    Title: Design and synthesis of some acridine-piperazine hybrids for the improvement of cognitive dysfunction
    Sharma A, Piplani P
    Ref: Chemical Biology Drug Des, 90:926, 2017 : PubMed


    Title: Functional characterization of hypothetical proteins of Mycobacterium tuberculosis with possible esterase/lipase signature: A Cumulative in silico and in vitro approach
    Kumar A, Sharma A, Kaur G, Makkar P, Kaur J
    Ref: J Biomol Struct Dyn, 35:1226, 2016 : PubMed


    Title: Potential association of reduced cholinesterase activity with Trypanosoma evansi pathogenesis in buffaloes
    Singh SK, Singh VK, Yadav BK, Nakade UP, Kumari P, Srivastava MK, Sharma A, Choudhary S, Swain D, Garg SK
    Ref: Vet Parasitol, 225:29, 2016 : PubMed


    Title: Evaluation of pesticide residues in human blood samples from Punjab (India)
    Bedi JS, Gill JP, Kaur P, Sharma A, Aulakh RS
    Ref: Vet World, 8:66, 2015 : PubMed


    Title: NDRG1 links p53 with proliferation-mediated centrosome homeostasis and genome stability
    Croessmann S, Wong HY, Zabransky DJ, Chu D, Mendonca J, Sharma A, Mohseni M, Rosen DM, Scharpf RB and Park BH <12 more author(s)>
    Ref: Proc Natl Acad Sci U S A, 112:11583, 2015 : PubMed


    Title: Genome sequencing of four Aureobasidium pullulans varieties: biotechnological potential, stress tolerance, and description of new species
    Gostincar C, Ohm RA, Kogej T, Sonjak S, Turk M, Zajc J, Zalar P, Grube M, Sun H and Gunde-Cimerman N <7 more author(s)>
    Ref: BMC Genomics, 15:549, 2014 : PubMed


    Title: Genome analysis of a major urban malaria vector mosquito, Anopheles stephensi
    Jiang X, Peery A, Hall AB, Sharma A, Chen XG, Waterhouse RM, Komissarov A, Riehle MM, Shouche Y and Tu Z <25 more author(s)>
    Ref: Genome Biol, 15:459, 2014 : PubMed


    Title: Structural basis of malaria parasite lysyl-tRNA synthetase inhibition by cladosporin
    Khan S, Sharma A, Belrhali H, Yogavel M
    Ref: J Struct Funct Genomics, 15:63, 2014 : PubMed


    Title: Effect of ethanolic extract of Acacia auriculiformis leaves on learning and memory in rats
    Sharma A, Shetty M, Parida A, Adiga S, Kamath S, Sowjanya
    Ref: Pharmacognosy Res, 6:246, 2014 : PubMed


    Title: Role of Medium Chain Triglycerides (Axona(R)) in the Treatment of Mild to Moderate Alzheimer's Disease
    Sharma A, Bemis M, Desilets AR
    Ref: Am J Alzheimers Dis Other Demen, 29:409, 2014 : PubMed


    Title: Draft Genome Sequence of Arthrobacter crystallopoietes Strain BAB-32, Revealing Genes for Bioremediation
    Joshi MN, Pandit AS, Sharma A, Pandya RV, Desai SM, Saxena AK, Bagatharia SB
    Ref: Genome Announc, 1:, 2013 : PubMed


    Title: Draft Genome Sequence of the Halophilic Bacterium Halobacillus sp. Strain BAB-2008
    Joshi MN, Pandit AS, Sharma A, Pandya RV, Saxena AK, Bagatharia SB
    Ref: Genome Announc, 1:, 2013 : PubMed


    Title: Draft Genome Sequence of Brevibacillus sp. Strain BAB-2500, a Strain That Might Play an Important Role in Agriculture
    Joshi MN, Sharma A, Pandit AS, Pandya RV, Saxena AK, Bagatharia SB
    Ref: Genome Announc, 1:e00021, 2013 : PubMed


    Title: Draft Genome Sequence of Sphingobium quisquiliarum Strain P25T, a Novel Hexachlorocyclohexane (HCH)-Degrading Bacterium Isolated from an HCH Dumpsite
    Kumar Singh A, Sangwan N, Sharma A, Gupta V, Khurana JP, Lal R
    Ref: Genome Announc, 1:, 2013 : PubMed


    Title: Acetylcholinesterase Inhibitors from QSAR Point of View: How Close are We?
    Sharma A, Piplani P
    Ref: Cent Nerv Syst Agents Med Chem, 13:71, 2013 : PubMed


    Title: Molecular docking and receptor-specific 3D-QSAR studies of acetylcholinesterase inhibitors
    Deb PK, Sharma A, Piplani P, Akkinepally RR
    Ref: Mol Divers, 16:803, 2012 : PubMed


    Title: Organochlorine pesticide, endosulfan induced cellular and organismal response in Drosophila melanogaster
    Sharma A, Mishra M, Shukla AK, Kumar R, Abdin MZ, Chowdhuri DK
    Ref: J Hazard Mater, 221-222:275, 2012 : PubMed


    Title: The B73 maize genome: complexity, diversity, and dynamics
    Schnable PS, Ware D, Fulton RS, Stein JC, Wei F, Pasternak S, Liang C, Zhang J, Fulton L and Wilson RK <147 more author(s)>
    Ref: Science, 326:1112, 2009 : PubMed


    Title: Optimization of physical parameters for lipase production from Arthrobacter sp. BGCC#490
    Sharma A, Bardhan D, Patel R
    Ref: Indian J Biochem Biophys, 46:178, 2009 : PubMed


    Title: A high performance lipase preparation: characterization and atomic force microscopy
    Shah S, Sharma A, Varandani D, Mehta B, Gupta MN
    Ref: J Nanosci Nanotechnol, 7:2157, 2007 : PubMed


    Title: Preparation of cross-linked enzyme aggregates by using bovine serum albumin as a proteic feeder
    Shah S, Sharma A, Gupta MN
    Ref: Analytical Biochemistry, 351:207, 2006 : PubMed


    Title: Novel biotinylated phenylarsonous acids as bifunctional reagents for spatially close thiols: studies on reduced antibodies and the agonist binding site of reduced Torpedo nicotinic receptors
    Moaddel R, Sharma A, Huseni T, Jones GS, Jr., Hanson RN, Loring RH
    Ref: Bioconjug Chem, 10:629, 1999 : PubMed


    Title: Effects of BN-50730 (PAF receptor antagonist) and physostigmine (AChE inhibitor) on learning and memory in mice
    Singh N, Sharma A, Singh M
    Ref: Methods Find Exp Clin Pharmacol, 19:585, 1998 : PubMed


    Title: Pharmacological basis of drug therapy of Alzheimer's disease
    Sharma A, Parikh V, Singh M
    Ref: Indian J Exp Biol, 35:1146, 1997 : PubMed


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