A85-Feruloyl-Esterase

Relationship

Family: A85-Feruloyl-Esterase

Block: X

Parent Family: Antigen85c

Comment

Feruloyl esterases play a key role in the degradation of the intricate structure of the plant cell wall by hydrolysing the ferulate ester groups involved in the cross-linking between hemicelluloses and between hemicellulose and lignin. It belongs to a supramolecular assembly termed a cellulosome. This multienzyme complex possesses in addition to its well-described cellulolytic activity an apparatus specific for xylan degradation. Feruloyl esterases, Cinnamic acid esterases hydrolyze the ferulate groups involved in the crosslinking of arabinoxylans to lignin and thus play a key role in the degradation of the plant cell wall. clotm-xyny corresponds to the feruloyl esterase module from a 5 domain xylanase Xyn10B. This family contains enzymes corresponding to a subset of the Carbohydrate Esterase family CE1 in CAZy - Carbohydrate-Active enZYmes database (CE_1) with Ser His Asp catalytic triad. Here most of the A85-Feruloyl-Esterase are bacterial enzymes but there are few fungi proteins that belong to this family and are farther related to the other fungi feruloyl esterase belonging to other families (Tannase (Aspergillus Niger FaeB) ; 6_AlphaBeta_hydrolase, Lipase_3 (Aspergillus Niger FaeA); Esterase_phb (Penicillium funiculosum FaeB Piromyces equi ESTA). Feruloyl esterases are distributed in different sub-classes type-A B C,D and E and fall respectively in the following families. Type-A in Lipase_3, Type-B in Esterase_phb (PHB depolymerase), Type-C in Tannase, Type-D in FaeC, Type-E in A85-Feruloyl-Esterase, Type-F in BD-FAE

Database

Interpro : IPR000801 Esterase_put

PIRSF : No PIRSF

Pdoc : No Pdoc

Pfam : PF00756 Esterase

Prints : No Print

EC Number : No EC Number

Sequences

Peptide in Fasta
Nucleotide in Fasta
Alignment with Multalin Text only
Seed alignment with MAFFT No colour
Alignment with MAFFT No colour
Dendrogram The dnd file

Structures (28)

Genes Proteins in A85-Feruloyl-Esterase family (302)

Fragments of genes in A85-Feruloyl-Esterase family (18)

Structures in A85-Feruloyl-Esterase family (28)

Substrates in A85-Feruloyl-Esterase family (11)

Inhibitors in A85-Feruloyl-Esterase family (1)

References (5)

Title : Contributions of a unique beta-clamp to substrate recognition illuminates the molecular basis of exolysis in ferulic acid esterases - Gruninger_2016_Biochem.J_473_839
Author(s) : Gruninger RJ , Cote C , McAllister TA , Abbott DW
Ref : Biochemical Journal , 473 :839 , 2016
PubMedID: 27026397
Gene_locus related to this paper: 9fung-f2ycb6

Title : Review on technological and scientific aspects of feruloyl esterases: A versatile enzyme for biorefining of biomass - Gopalan_2015_Bioresour.Technol_193_534
Author(s) : Gopalan N , Rodriguez-Duran LV , Saucedo-Castaneda G , Nampoothiri KM
Ref : Bioresour Technol , 193 :534 , 2015
PubMedID: 26159377

Title : Isolation and characterization of a ferulic acid esterase (Fae1A) from the rumen fungus Anaeromyces mucronatus - Qi_2011_J.Appl.Microbiol_110_1341
Author(s) : Qi M , Wang P , Selinger LB , Yanke LJ , Forster RJ , McAllister TA
Ref : J Appl Microbiol , 110 :1341 , 2011
PubMedID: 21362116
Gene_locus related to this paper: 9fung-f2ycb6

Title : Molecular determinants of substrate specificity in the feruloyl esterase module of xylanase 10B from Clostridium thermocellum - Tarbouriech_2005_Acta.Crystallogr.D.Biol.Crystallogr_61_194
Author(s) : Tarbouriech N , Prates JA , Fontes CM , Davies GJ
Ref : Acta Crystallographica D Biol Crystallogr , 61 :194 , 2005
PubMedID: 15681871
Gene_locus related to this paper: clotm-xyny

Title : The Structure of the Feruloyl Esterase Module of Xylanase 10B from Clostridium thermocellum Provides Insights into Substrate Recognition - Prates_2001_Structure_9_1183
Author(s) : Prates JA , Tarbouriech N , Charnock SJ , Fontes CM , Ferreira LM , Davies GJ
Ref : Structure , 9 :1183 , 2001
PubMedID: 11738044
Gene_locus related to this paper: clotm-xyny