FAAH inhibitor

General

Fatty acid amide hydrolase (FAAH) is not an alpha/beta hydrolase, but acts on similar compounds as other alpha/beta hydrolases and these enzymes share substrates and inhibitors
Inhibitor Main targeted enzyme families Type Structure
Cpd37-Fluoroindol-carbamate Monoglyceridelipase_lysophospholip Multitarget Carbamate Indole FAAH inhibitor Alkyl linked bis-ligand
SPB01403 Monoglyceridelipase_lysophospholip Carbamate FAAH inhibitor Multitarget Sulfur Compound
BIA-10-2474 Carb_B_Chordata ABHD6-Lip Pyridine Imidazole FAAH inhibitor Multitarget Carboxamide
AM3506 Monoglyceridelipase_lysophospholip FAAH inhibitor Sulfur Compound Sulfonyl
SCHEMBL19358888 Epoxide_hydrolase Urea derivative Benzoate FAAH inhibitor Multitarget
t-TUCB Epoxide_hydrolase Urea derivative Multitarget FAAH inhibitor
JZL195 Monoglyceridelipase_lysophospholip Carb_B_Chordata ABHD6-Lip Piperazine FAAH inhibitor Multitarget pNP Phenoxyphenyl
JZL184 Monoglyceridelipase_lysophospholip Carb_B_Chordata ABHD6-Lip Piperidine Benzodioxo FAAH inhibitor Multitarget pNP
AM6701 ABHD6-Lip Monoglyceridelipase_lysophospholip Biphenyl Urea derivative Cannabinoid-Receptor-ligand FAAH inhibitor Multitarget Carboxamide Tetrazol
EOPF Organophosphate NTE inhibitor Not A\/B H target FAAH inhibitor
Methyl-arachidonyl-fluorophosphonate CGI-58_ABHD5_ABHD4 PC-sterol_acyltransferase Monoglyceridelipase_lysophospholip Cannabinoid-Receptor-ligand Organophosphate FAAH inhibitor Multitarget
IDFP PC-sterol_acyltransferase Monoglyceridelipase_lysophospholip Organophosphate FAAH inhibitor Multitarget
IDFPen PC-sterol_acyltransferase Organophosphate Multitarget FAAH inhibitor
Phenmedipham ACHE BCHE Carbamate Herbicide Not A\/B H target FAAH inhibitor
LY2183240 Monoglyceridelipase_lysophospholip Arylacetamide_deacetylase ABHD6-Lip Cannabinoid-Receptor-ligand Biphenyl Urea derivative FAAH inhibitor Multitarget Carboxamide Tetrazol
URB597 Monoglyceridelipase_lysophospholip Carbamate Biphenyl FAAH inhibitor Multitarget