Haloperoxidase

Relationship

Family: Haloperoxidase

Block: X

Parent Family: Abhydrolase_6

Comment

Non-heme Peroxidase. Bacterial and fungi non-heme bromo- and chloro-peroxidases family. Haloperoxidases catalyze the halogenation of organic compounds in the presence of halide ions and peroxides such as H2O2. They are named after the most electronegative halide they are able to oxidize and are classified according to their cofactor dependence as heme-type, vanadium-dependent and metal-free haloperoxidases (WARNING Only metal free haloperoxidases are alpha beta hydrolases with a Ser-His-Asp catalytic triad in the active center. This family contains also homologous arylesterases.)

Database

Interpro : IPR000073 Alpha\/beta hydrolase fold-1

PIRSF : PIRSF037176 non-heme peroxidase

Pdoc : No Pdoc

Pfam : PF12697 Abhydrolase_6

Prints : No Print

EC Number : 1.11.1.10

Sequences

Peptide in Fasta
Nucleotide in Fasta
Alignment with Multalin Text only
Seed alignment with MAFFT No colour
Alignment with MAFFT No colour
Dendrogram The dnd file

Structures (29)

Genes Proteins in Haloperoxidase family (438)

Fragments of genes in Haloperoxidase family (12)

Structures in Haloperoxidase family (29)

Substrates in Haloperoxidase family (8)

Inhibitors in Haloperoxidase family (3)

References (7)

Title : Different active-site loop orientation in serine hydrolases versus acyltransferases - Jiang_2011_Chembiochem_12_768
Author(s) : Jiang Y , Morley KL , Schrag JD , Kazlauskas RJ
Ref : Chembiochem , 12 :768 , 2011
PubMedID: 21351219
Gene_locus related to this paper: psefl-este

Title : Switching catalysis from hydrolysis to perhydrolysis in Pseudomonas fluorescens esterase - Yin_2010_Biochemistry_49_1931
Author(s) : Yin DL , Bernhardt P , Morley KL , Jiang Y , Cheeseman JD , Purpero V , Schrag JD , Kazlauskas RJ
Ref : Biochemistry , 49 :1931 , 2010
PubMedID: 20112920
Gene_locus related to this paper: psefl-este

Title : Stereoselective esterase from Pseudomonas putida IFO12996 reveals alpha\/beta hydrolase folds for D-beta-acetylthioisobutyric acid synthesis - Elmi_2005_J.Bacteriol_187_8470
Author(s) : Elmi F , Lee HT , Huang JY , Hsieh YC , Wang YL , Chen YJ , Shaw SY , Chen CJ
Ref : Journal of Bacteriology , 187 :8470 , 2005
PubMedID: 16321951
Gene_locus related to this paper: psepu-bpest

Title : The crystal structure of a (-) gamma-lactamase from an Aureobacterium species reveals a tetrahedral intermediate in the active site - Line_2004_J.Mol.Biol_338_519
Author(s) : Line K , Isupov MN , Littlechild JA
Ref : Journal of Molecular Biology , 338 :519 , 2004
PubMedID: 15081810
Gene_locus related to this paper: uncmi-Q8GJP7

Title : Structure of an aryl esterase from Pseudomonas fluorescens - Cheeseman_2004_Acta.Crystallogr.D.Biol.Crystallogr_60_1237
Author(s) : Cheeseman JD , Tocilj A , Park S , Schrag JD , Kazlauskas RJ
Ref : Acta Crystallographica D Biol Crystallogr , 60 :1237 , 2004
PubMedID: 15213385
Gene_locus related to this paper: psefl-este

Title : Structural investigation of the cofactor-free chloroperoxidases - Hofmann_1998_J.Mol.Biol_279_889
Author(s) : Hofmann B , Tolzer S , Pelletier I , Altenbuchner J , van Pee KH , Hecht HJ
Ref : Journal of Molecular Biology , 279 :889 , 1998
PubMedID: 9642069
Gene_locus related to this paper: psefl-cpoF , strau-brpa2 , strau-cpoT , strli-cpoL

Title : The metal-ion-free oxidoreductase from Streptomyces aureofaciens has an alpha\/beta hydrolase fold - Hecht_1994_Nat.Struct.Biol_1_532
Author(s) : Hecht HJ , Sobek H , Haag T , Pfeifer O , van Pee KH
Ref : Nat Struct Biol , 1 :532 , 1994
PubMedID: 7664081
Gene_locus related to this paper: strau-brpa2