Mycobacterium tuberculosis, Mycobacterium bovis, (Rv2214c, MT2270, MTCY190.25c) Probable oxidoreductase ephd gene Short-chain type dehydrogenase
N-terminus corresponds to several epoxide hydrolases of plants and M. tuberculosis e.g. MTCY9F925. PfamA Abhydrolase_1 56 296. || only n-term Pfam A Abhydrolase_6 32 293. || There are more than 1000 strains. Other Uniprot entries and list of strains can be found with the link: Other strains CDC 1551 \/ Oshkosh
Family : Epoxide_hydrolase
Block : X
Position in NCBI Life Tree : Mycobacterium tuberculosis
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms N E > Bacteria N E > Terrabacteria group N E > Actinobacteria [phylum] N E > Actinobacteria [class] N E > Corynebacteriales N E > Mycobacteriaceae N E > Mycobacterium N E > Mycobacterium tuberculosis complex N E > Mycobacterium tuberculosis N E > cellular organisms N E > Bacteria N E > Terrabacteria group N E > Actinobacteria [phylum] N E > Actinobacteria [class] N E > Corynebacteriales N E > Mycobacteriaceae N E > Mycobacterium N E > Mycobacterium tuberculosis complex N E > Mycobacterium tuberculosis N E > cellular organisms N E > Bacteria N E > Terrabacteria group N E > Actinobacteria [phylum] N E > Actinobacteria [class] N E > Corynebacteriales N E > Mycobacteriaceae N E > Mycobacterium N E > Mycobacterium tuberculosis complex N E > Mycobacterium tuberculosis N EMPATQQMSRL VDSPDGVRIA VYHEGNPDGP TVVLVHGFPD SHVLWDGVVP LLAERFRIVR YDNRGVGRSS VPKPISAYTM AHFADDFDAV IGELSPGEPV HVLAHDWGSV GVWEYLRRPG ASDRVASFTS VSGPSQDHLV NYVYGGLRRP WRPRTFLRAI SQTLRLSYMA LFSVPVVAPL LLRVALSSAA VRRNMVGDIP VDQIHHSETL ARDAAHSVKT YPANYFRSFS SSRRGRAIPI VDVPVQLIVN SQDPYVRPYG YDQTARWVPR LWRRDIKAGH FSPMSHPQVM AAAVHDFADL ADGK
| Title : Tailored phenyl ureas eradicate drug-resistant Mycobacterium tuberculosis by targeting mycolic acid cell wall assembly - Mostert_2025_Chem.Sci__ |
| Author(s) : Mostert D , Braun J , Zimmerman MD , Engelhart CA , Berndl S , Quoika PK , Kany AM , Proietto J , Penalva-Lopez S , Wallach JB , Hirsch AKH , Zacharias M , Schnappinger D , Dartois V , Sieber SA |
| Ref : Chem Sci , : , 2025 |
| Abstract : |
| PubMedSearch : Mostert_2025_Chem.Sci__ |
| PubMedID: 40313523 |
| Gene_locus related to this paper: myctu-ephd , myctu-ephF |
| Title : Tailored phenyl ureas eradicate drug-resistant Mycobacterium tuberculosis by targeting mycolic acid cell wall assembly - Mostert_2025_Chem.Sci__ |
| Author(s) : Mostert D , Braun J , Zimmerman MD , Engelhart CA , Berndl S , Quoika PK , Kany AM , Proietto J , Penalva-Lopez S , Wallach JB , Hirsch AKH , Zacharias M , Schnappinger D , Dartois V , Sieber SA |
| Ref : Chem Sci , : , 2025 |
| Abstract : |
| PubMedSearch : Mostert_2025_Chem.Sci__ |
| PubMedID: 40313523 |
| Gene_locus related to this paper: myctu-ephd , myctu-ephF |
| Title : Tailored phenyl ureas eradicate drug-resistant Mycobacterium tuberculosis by targeting mycolic acid cell wall assembly - Mostert_2025_Chem.Sci__ |
| Author(s) : Mostert D , Braun J , Zimmerman MD , Engelhart CA , Berndl S , Quoika PK , Kany AM , Proietto J , Penalva-Lopez S , Wallach JB , Hirsch AKH , Zacharias M , Schnappinger D , Dartois V , Sieber SA |
| Ref : Chem Sci , : , 2025 |
| Abstract : |
| PubMedSearch : Mostert_2025_Chem.Sci__ |
| PubMedID: 40313523 |
| Gene_locus related to this paper: myctu-ephd , myctu-ephF |
| Title : Mycobacterial Epoxide Hydrolase EphD Is Inhibited by Urea and Thiourea Derivatives - Madacki_2021_Int.J.Mol.Sci_22_ |
| Author(s) : Madacki J , Kopal M , Jackson M , Kordulakova J |
| Ref : Int J Mol Sci , 22 : , 2021 |
| Abstract : |
| PubMedSearch : Madacki_2021_Int.J.Mol.Sci_22_ |
| PubMedID: 33809178 |
| Gene_locus related to this paper: myctu-ephd |
| Title : Mycobacterial Epoxide Hydrolase EphD Is Inhibited by Urea and Thiourea Derivatives - Madacki_2021_Int.J.Mol.Sci_22_ |
| Author(s) : Madacki J , Kopal M , Jackson M , Kordulakova J |
| Ref : Int J Mol Sci , 22 : , 2021 |
| Abstract : |
| PubMedSearch : Madacki_2021_Int.J.Mol.Sci_22_ |
| PubMedID: 33809178 |
| Gene_locus related to this paper: myctu-ephd |
| Title : Mycobacterial Epoxide Hydrolase EphD Is Inhibited by Urea and Thiourea Derivatives - Madacki_2021_Int.J.Mol.Sci_22_ |
| Author(s) : Madacki J , Kopal M , Jackson M , Kordulakova J |
| Ref : Int J Mol Sci , 22 : , 2021 |
| Abstract : |
| PubMedSearch : Madacki_2021_Int.J.Mol.Sci_22_ |
| PubMedID: 33809178 |
| Gene_locus related to this paper: myctu-ephd |
| Title : Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry - Kelkar_2011_Mol.Cell.Proteomics_10_M111.011627 |
| Author(s) : Kelkar DS , Kumar D , Kumar P , Balakrishnan L , Muthusamy B , Yadav AK , Shrivastava P , Marimuthu A , Anand S , Sundaram H , Kingsbury R , Harsha HC , Nair B , Prasad TS , Chauhan DS , Katoch K , Katoch VM , Chaerkady R , Ramachandran S , Dash D , Pandey A |
| Ref : Mol Cell Proteomics , 10 :M111 011627 , 2011 |
| Abstract : |
| PubMedSearch : Kelkar_2011_Mol.Cell.Proteomics_10_M111.011627 |
| PubMedID: 21969609 |
| Gene_locus related to this paper: myctu-ephA , myctu-ephB , myctu-ephd , myctu-linb , myctu-MBTB , myctu-PKS13 , myctu-Rv1833c , myctu-RV2296 , myctu-RV2695 , myctu-RV2765 |
| Title : Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry - Kelkar_2011_Mol.Cell.Proteomics_10_M111.011627 |
| Author(s) : Kelkar DS , Kumar D , Kumar P , Balakrishnan L , Muthusamy B , Yadav AK , Shrivastava P , Marimuthu A , Anand S , Sundaram H , Kingsbury R , Harsha HC , Nair B , Prasad TS , Chauhan DS , Katoch K , Katoch VM , Chaerkady R , Ramachandran S , Dash D , Pandey A |
| Ref : Mol Cell Proteomics , 10 :M111 011627 , 2011 |
| Abstract : |
| PubMedSearch : Kelkar_2011_Mol.Cell.Proteomics_10_M111.011627 |
| PubMedID: 21969609 |
| Gene_locus related to this paper: myctu-ephA , myctu-ephB , myctu-ephd , myctu-linb , myctu-MBTB , myctu-PKS13 , myctu-Rv1833c , myctu-RV2296 , myctu-RV2695 , myctu-RV2765 |
| Title : Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry - Kelkar_2011_Mol.Cell.Proteomics_10_M111.011627 |
| Author(s) : Kelkar DS , Kumar D , Kumar P , Balakrishnan L , Muthusamy B , Yadav AK , Shrivastava P , Marimuthu A , Anand S , Sundaram H , Kingsbury R , Harsha HC , Nair B , Prasad TS , Chauhan DS , Katoch K , Katoch VM , Chaerkady R , Ramachandran S , Dash D , Pandey A |
| Ref : Mol Cell Proteomics , 10 :M111 011627 , 2011 |
| Abstract : |
| PubMedSearch : Kelkar_2011_Mol.Cell.Proteomics_10_M111.011627 |
| PubMedID: 21969609 |
| Gene_locus related to this paper: myctu-ephA , myctu-ephB , myctu-ephd , myctu-linb , myctu-MBTB , myctu-PKS13 , myctu-Rv1833c , myctu-RV2296 , myctu-RV2695 , myctu-RV2765 |